UA95769C2 - N-substituted piperidines and their use as pharmaceuticals - Google Patents
N-substituted piperidines and their use as pharmaceuticalsInfo
- Publication number
- UA95769C2 UA95769C2 UAA200700714A UAA200700714A UA95769C2 UA 95769 C2 UA95769 C2 UA 95769C2 UA A200700714 A UAA200700714 A UA A200700714A UA A200700714 A UAA200700714 A UA A200700714A UA 95769 C2 UA95769 C2 UA 95769C2
- Authority
- UA
- Ukraine
- Prior art keywords
- pharmaceuticals
- substituted piperidines
- diseases associated
- dehydrogenase type
- steroid dehydrogenase
- Prior art date
Links
- -1 N-substituted piperidines Chemical class 0.000 title abstract 3
- 239000003814 drug Substances 0.000 title 1
- 101710088194 Dehydrogenase Proteins 0.000 abstract 2
- 102000003979 Mineralocorticoid Receptors Human genes 0.000 abstract 2
- 108090000375 Mineralocorticoid Receptors Proteins 0.000 abstract 2
- 201000010099 disease Diseases 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- PQSUYGKTWSAVDQ-ZVIOFETBSA-N Aldosterone Chemical compound C([C@@]1([C@@H](C(=O)CO)CC[C@H]1[C@@H]1CC2)C=O)[C@H](O)[C@@H]1[C@]1(C)C2=CC(=O)CC1 PQSUYGKTWSAVDQ-ZVIOFETBSA-N 0.000 abstract 1
- PQSUYGKTWSAVDQ-UHFFFAOYSA-N Aldosterone Natural products C1CC2C3CCC(C(=O)CO)C3(C=O)CC(O)C2C2(C)C1=CC(=O)CC2 PQSUYGKTWSAVDQ-UHFFFAOYSA-N 0.000 abstract 1
- 229960002478 aldosterone Drugs 0.000 abstract 1
- 239000005557 antagonist Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Abstract
The present invention relates to inhibitors of 11-β hydroxyl steroid dehydrogenase type 1, antagonists of the mineralocorticoid receptor (MR), and pharmaceutical compositions thereof. The compounds of the invention can be useful in the treatment of various diseases associated with expression or activity of 11-β hydroxyl steroid dehydrogenase type 1 and/or diseases associated with aldosterone excess.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US58255704P | 2004-06-24 | 2004-06-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA95769C2 true UA95769C2 (en) | 2011-09-12 |
Family
ID=38091634
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UAA200700714A UA95769C2 (en) | 2004-06-24 | 2005-06-23 | N-substituted piperidines and their use as pharmaceuticals |
Country Status (3)
| Country | Link |
|---|---|
| CN (1) | CN1993128A (en) |
| NO (1) | NO20070371L (en) |
| UA (1) | UA95769C2 (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102009014484A1 (en) * | 2009-03-23 | 2010-09-30 | Bayer Schering Pharma Aktiengesellschaft | Substituted piperidines |
| DE102009022896A1 (en) * | 2009-05-27 | 2010-12-02 | Bayer Schering Pharma Aktiengesellschaft | Substituted piperidines |
| WO2013020440A1 (en) * | 2011-08-09 | 2013-02-14 | 上海医药集团股份有限公司 | Amide derivate, and preparation method therefor, pharmaceutical composition and use thereof |
-
2005
- 2005-06-23 UA UAA200700714A patent/UA95769C2/en unknown
- 2005-06-23 CN CN 200580021164 patent/CN1993128A/en active Pending
-
2007
- 2007-01-19 NO NO20070371A patent/NO20070371L/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CN1993128A (en) | 2007-07-04 |
| NO20070371L (en) | 2007-03-08 |
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