UA94028C2 - Amido compounds and their use as pharmaceuticals - Google Patents
Amido compounds and their use as pharmaceuticalsInfo
- Publication number
- UA94028C2 UA94028C2 UAA200700717A UAA200700717A UA94028C2 UA 94028 C2 UA94028 C2 UA 94028C2 UA A200700717 A UAA200700717 A UA A200700717A UA A200700717 A UAA200700717 A UA A200700717A UA 94028 C2 UA94028 C2 UA 94028C2
- Authority
- UA
- Ukraine
- Prior art keywords
- pharmaceuticals
- amido compounds
- diseases associated
- compounds
- dehydrogenase type
- Prior art date
Links
- 125000003368 amide group Chemical group 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 101710088194 Dehydrogenase Proteins 0.000 abstract 2
- 102000003979 Mineralocorticoid Receptors Human genes 0.000 abstract 2
- 108090000375 Mineralocorticoid Receptors Proteins 0.000 abstract 2
- 201000010099 disease Diseases 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- -1 hydroxyl steroid Chemical class 0.000 abstract 2
- PQSUYGKTWSAVDQ-ZVIOFETBSA-N Aldosterone Chemical compound C([C@@]1([C@@H](C(=O)CO)CC[C@H]1[C@@H]1CC2)C=O)[C@H](O)[C@@H]1[C@]1(C)C2=CC(=O)CC1 PQSUYGKTWSAVDQ-ZVIOFETBSA-N 0.000 abstract 1
- PQSUYGKTWSAVDQ-UHFFFAOYSA-N Aldosterone Natural products C1CC2C3CCC(C(=O)CO)C3(C=O)CC(O)C2C2(C)C1=CC(=O)CC2 PQSUYGKTWSAVDQ-UHFFFAOYSA-N 0.000 abstract 1
- 229960002478 aldosterone Drugs 0.000 abstract 1
- 239000005557 antagonist Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Landscapes
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
Abstract
The present invention relates to inhibitors of 11-β hydroxyl steroid dehydrogenase type 1, antagonists of the miner-alocorticoid receptor (MR), and pharmaceutical compositions thereof. The compounds of the invention can be useful in the treatment of various diseases associated with expression or activity of 11-β hydroxyl steroid dehydrogenase type 1 and/or diseases associated with aldosterone excess.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US58255604P | 2004-06-24 | 2004-06-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA94028C2 true UA94028C2 (en) | 2011-04-11 |
Family
ID=38185392
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UAA200700717A UA94028C2 (en) | 2004-06-24 | 2005-06-23 | Amido compounds and their use as pharmaceuticals |
Country Status (3)
| Country | Link |
|---|---|
| CN (1) | CN1988908A (en) |
| UA (1) | UA94028C2 (en) |
| ZA (1) | ZA200610602B (en) |
-
2005
- 2005-06-23 CN CN 200580020965 patent/CN1988908A/en active Pending
- 2005-06-23 UA UAA200700717A patent/UA94028C2/en unknown
-
2006
- 2006-12-15 ZA ZA200610602A patent/ZA200610602B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN1988908A (en) | 2007-06-27 |
| ZA200610602B (en) | 2008-08-27 |
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