UA72741C2 - Method of controlling weed plants and an herbicidal agent (variants) - Google Patents

Abstract

In order to control weeds in corn cultures consisting of tolerant or resistant mutants or transgenic corn plants, herbicide combinations (A) + (B), optionally in the presence of safeners, are particularly suitable, said combinations having an active content of; (A) herbicides exhibiting broad-spectrum effectiveness from group (A1) glufosinate(salts) and allied compounds; (A2) glyphosate(salts) and allied compounds such as sulfosate and (A3) imidazolinones, (A4) herbicidal azoles from the group of protoporphyrinogen oxidase inhibitors (PPO inhibitors) (A5) cyclohexanedion herbicides and (A6) heteroaryloxyphenoxy propionic acid herbicides and (B) one or more herbicides from the group of compounds consisting of (B0) one or more herbicides structurally different from the above-mentioned group (A), or (BI) herbicides exhibiting activity against monocotyledonous and dicotyledonous weeds with an effect on both the foliage and the soil or (B2) herbicides which can be selectively used in corn against dicotyledonous weeds, (B3) herbicides having an effect on both the foliage and the soil and which can be selectively used in corn primarily against dicotyledonous weeds or herbicides from several groups consisting of (B0) to (B3) and the corn cultures exhibiting tolerance in relation to the herbicides (A) and (B), optionally in the presence of safeners, contained in said combination.

Description

Description of the invention

The invention relates to the field of plant protection products that can be used to control 2 weedy plants in tolerant or resistant corn crops and contain a combination of two or more herbicides as an active herbicidal component.

With the introduction of tolerant or resistant varieties and lines of corn crops, in particular, transgenic varieties and lines of corn crops, the well-known system of weed control is replenished with new active substances that are not selective in themselves in conventional varieties of corn. The active substances are, for example, 70 known broad-spectrum herbicides, such as glyphosates, sulfosates, glufosinates, bialaphos and herbicides - imidazolinone derivatives (herbicides (A)), which can now be used for tolerant crops developed for them. The effectiveness of these herbicides in relation to weedy plants (weeds) in tolerant crops is at a high level, but still depends - similarly, as in the case of treatment with other herbicides - on the type of herbicide used, its consumption rates (amounts that are introduced) , the current 12th form of the composition, from the type of weeds that are eradicated, from the climate and soil condition, and so on. In addition, there are cases when herbicides show weak activity (or no activity at all) in relation to certain types of weeds.

The next criterion is the duration of action, respectively, the rate of disintegration of the herbicide. In some cases, it is also worth taking into account changes in the sensitivity of weeds, which may occur with long-term use of herbicides or in the case of geographic specificity (geographical restrictions).

The loss of activity in relation to individual plants can be compensated only conditionally, if at all possible, due to the large amounts of herbicides used. In addition, there is always a need for methods that make it possible to achieve the effectiveness of herbicides with smaller amounts of active substances. When using smaller quantities, not only the amount of active substance required for administration decreases, but also, as a rule, the amount of necessary auxiliary means decreases. Both factors reduce economic costs and improve environmental conditions (tolerability) when treated with herbicides. Gee)

The possibility of improving the profile (character) of the use of the herbicide may consist in the combination of the active substance with one or more other active substances that bring the desired additional properties.

However, with the combined use of several substances, phenomena of physical and biological incompatibility are often detected, for example, - insufficient stability of the combined composition, decomposition of the active substance or antagonism of the active substances. "f

In contrast, combinations of active substances with a favorable profile of action, high stability and, if possible, with an enhanced effect due to synergism, which allow for a reduction in the quantities that are introduced, compared to the use of the combined active substances individually, are desirable. Gee!

It was strikingly found that the active substances from the group of the above-mentioned broad-spectrum herbicides (A).

Acting in combination with other herbicides from group (A) and in some cases with certain herbicides (B) together, they act in a particularly favorable way when they are used in corn crops that are suitable for the selective use of the first of the above-mentioned herbicides.

The subject of the invention is the use of a combination of herbicides for the control of weeds in corn crops, which is characterized by the fact that the corresponding combination of herbicides contains the following components, which act synergistically: c (A) a broad-spectrum herbicide from the group of compounds that consists of "from (AT) compounds of the formulas (А1) (АТ) 'Іre o -i perra ka (lu) kono Na Mne -I і" 20 where 7 means a residue of the formula -OH or a peptide residue of the formula -МНСН( СНЗСОМнеН(СНУЗ)СООН or т -МНЕСН(СНЗСОМнеНИСНоН(СНУЗИ)|СООН, and their esters and salts, mainly glufosinate and its salts with acids and bases, in particular, ammonium glufosinate, I-glufosinate and their salts, bidalafos and its salts with acids and bases and other derivatives of phosphinothricin, 29 (A2) compounds of the formula (A2) and their esters and salts,

Ф) о о (АТ) их ю и И во во во Тон (42) no No No mainly glyphosates and their salts with alkali metals and salts with amines, in particular, isopropylammonium glyphosates, and sulfosates, 6E (AZ) imdazolinones, mainly imazetapur, imazapur, imazametabenz, imazametabenzmethyl, imazaquin, imazamox, imazapic (AS 263 222) and their salts, and

(A4) azoles, which have herbicidal properties, from the group of proto-porphyrinogen oxidase inhibitors (PPO inhibitors), for example, UUS 9717 (-СОА276854), and (AB) herbicides - derivatives of cyclohexanedione, and if necessary, also (Аб) herbicides - derivatives of heteroaryloxyphenoxypropionic acid, and (B) one or more herbicides from the group of compounds, which consists of (BO) one or more structurally different herbicides from the aforementioned group (A) and/or (B1) herbicides that act against monocotyledons and dicotyledons of weedy plants, with foliar and soil action, and/or 70 (82) herbicides used selectively in corn crops against dicotyledonous weeds, and/or (83) foliar and per-pound herbicides that can be used selectively in corn crops mainly against dicotyledonous weeds, and corn crops are tolerant to herbicides (A) and (B), which are contained in a combination, in some cases in the presence of substances that promote safety.

With "structurally different herbicides from the named group (A)" in group (BO) only herbicides are considered, which are covered by the definition of group (A), but still are not contained in the corresponding combinations as a component (A).

Along with the combinations of herbicides that are claimed, other active substances from plant protection agents and auxiliaries, usually used for plant protection, and auxiliaries can be used in the composition.

Synergistic effects are observed when active substances (A) and (B) are used together, but they can still be detected also when used separately in time (separation into parts). It is also possible to apply herbicides or combinations of herbicides in several portions (sequential application), for example, pre-emergent application followed by post-emergent application, or early post-emergent application followed by mid- or late post-emergent application. In this case, it is preferable to simultaneously introduce the active substances of the current drug combination, in some cases in several portions. But it is also possible to introduce individual active substances of the combination divided in time, and in a certain case this can be beneficial. With such systemic i) application, other plant protection agents, such as fungicides, insecticides, acaricides and the like and/or various auxiliary substances, additives and/or fertilizers, can also be combined together (integrated).

Synergistic effects make it possible to reduce the used quantities of individual active components, to increase the effectiveness of the action against the same type of weedy plants at the same used quantities, to control species not previously covered (gaps), to expand the temporal space during application and/or as a result for users who apply - economically and environmentally beneficial weed control systems. uh-

For example, thanks to the combinations that are claimed, with (A)(B), synergistic increases in efficiency become possible, which are much and unexpectedly superior to the efficiency achieved with individual c

Зз5 active components (A) and (B). uh-

International application UUO-A-98/09525 describes a method of weed control in transgenic crops that are resistant to phosphorus-containing herbicides such as glufosinate or glyphosate, while using combinations of herbicides that contain glufosinate or glyphosate and at least one herbicide from the group that includes prosulfuron, primisulfuron, dicamba, pyridate, dimethenamid, metolachlor, flumeturon, "propahizafop, atrazine, clodinafop, norflurazon, ametryn, terbuthylazine, simazine, promethrin, MOA-402989 nt") with (Z-phenyl-4 -hydroxy-b6-chloropyridazine), a compound of the formula oh

M 8 in - 45 I. t where K means 4-chloro-2-fluoro-5-(methoxycarbonylmethylthio)phenyl, (known from the US patent I5-A-4671819),

СОА276854-1-allyloxycarbonyl-1-methylethyl ether -and 2-chloro-5-(3-methyl-2,6-dioxo-4-trifluoromethyl-3,6-dihydro-2H-pyrimidin-1-yl)benzoic acid ( - MUC9717, 1" 50 known from the US patent O5-A-5183492) and 4-oxetanyl ether 2-(M-(M-(4,6-dimethylpyrimidin-2-yl)aminocarbonyl|aminosulfonyl/benzoic acids) (known from the European -. and patent applications EP-A-496701). Details about the possible and those that are actually achieved effects can be read in the international application MUUO-A-98/09525. There are no examples of synergistic effects or conducting an experiment in certain cultures, as well as and specific combinations of two, three or more herbicides.

From the German patent application OE-A-2856260, some combinations of herbicides with glufosinate or

Y-glufosinate and other herbicides, such as allocsidim, linuron, MCPA, 2,4-O, dicamba, trichlopur,

IF) 2,4,5-T, MSRV and others. name) From the international application MUO-A-98/08353 and the European patent application EP-A 0 252 237, some combinations of herbicides with glufosin or glyphosate and other herbicides from a number of sulfonylurea(s), such as metsulforonmethyl, nicosulforon, primisulforon, are already known , rimsulforon and so on.

The use of combinations for the control of weed plants in the literature is shown only on a small number of plant species, but is not even shown on the examples.

Based on own experiments, it was established that there is a strikingly large difference between the applicability of combinations of herbicides mentioned in the international application UMO-A-08/09525 and in other sources, and other combinations of 65 herbicides of a new type in plant cultures.

According to the invention, combinations of herbicides are patented, which can be especially advantageously used in tolerant corn crops.

Compounds of formulas (A1)-(A4) are known or can be obtained by analogy with known methods.

The formula (Ai1) includes all stereoisomers and their mixtures, in particular, the racemate and, accordingly, the biologically active enantiomer, for example, I-glufosinate and its salts. Examples of active substances of the formula (A1) are the following: (A1.1) Glufosinate in the narrow sense, i.e. O, -2-amino-4-Hydroxy(methyl)phosphinylbutanoic acid, (A1.2) Glufosinate monoammonium salt, (A1 .3) I -Glufosinate, I - or (25)-2-amino-4-Hydroxy(methyl)phosphinyl|butanoic acid (Phosphinothricin) 70 (A1.4) | -lufosinate-monoammonium salt, (A1.5) Bialafos (or Bilanafos), i.e., I1-2-amino-4-Hydroxy(methyl)phosphine|butanoyl-i! -alanyl-I -alanine, in particular, its sodium salt.

The named herbicides (A1)-(A5) act on the green parts of plants and are known as broad-spectrum herbicides or continuous-action herbicides; they are inhibitors of glutamine synthetase enzyme in plants; see "pe Revgiiside 75 Mappspiai" 11p Eaiiop, Vgiivy Stor Rgoiesiop Soitspsi! 1997, 5. 643-645 frame. 120-121. In the event that the field of application in the post-emergence method of controlling weeds and unwanted grasses on plantations with crops and on non-cultivated land with the help of a special application technique also extends to inter-row control in agricultural field crops such as corn, cotton and similar, the use of selective herbicides in resistant transgenic cultures increases.

Glufosinate is usually used in the form of a salt, preferably an ammonium salt. Racemate glufosinate or glufosinate ammonium is usually used alone in dosages that lie between 200 and 2000 g AR/ha (-g a.i./ha- grams of active substance per hectare). At these dosages, glufosinate is effective when it acts on the green parts of plants. Because it breaks down in the soil with the help of microbes within several days, it does not have a sufficiently long effect in the soil. A similar situation also applies to the active substance Ha bialaphos sodium (identical to bialaphos sodium); see "Te Reviiside Mapa" 11 Ediiop, Vgiivy Stor o

Sociological Research 1997, 5. 120-121.

In the combinations that are declared, as a rule, clearly less active substance (At) is needed, for example, the amount used can be in the range from 20 to 800, preferably from 20 to 600 grams of the active substance - glufosinate per hectare (g AR/ha or g a.i/ha). Appropriate amounts, preferably amounts listed in moles per 7 hectares, are also suitable for glufosinate ammonium and biapaphos or bialaphos-sodium.

Combinations with foliar herbicides (A!) are used in a targeted manner in grain crops that are resistant or tolerant to compounds (At). Some tolerant grain crops, which are made by genetic engineering, are already known and used in practice, see article in the magazine "7isKegtibre" 47.

Uagdapd (1998), 5. 217 I; for obtaining transgenic plants that are resistant to glufosinate, see see European patent applications EP-A-0242246, EP-A-242236, EP-A-257542, EP-A-275967, EP-A-05130541. -

Examples of compounds (Ag) are (A2.1) Glyphosate, that is, M-(phosphonomethyl)glycine, (A2.2) Glyphosate - monoisopropylammonium salt, (A2.3) Glyphosate - sodium salt, (A2.4) Sulphosate, ie, M-(phosphonomethyl)glycine trimesium salt - - with M-(phosphonomethyl)glycine trimethylsulfoxonium salt. and Glyphosate is usually used in the form of a salt, mainly monoisopropylammonium salt, or "» trimethylsulfoxonium salt (trimesium salt - sulfosate). Based on the free acid of glyphosate, the final dosage is in the range of 0.5-5 kg AR/ha. Glyphosate from the point of view of some technical aspects similar to glufosinate, but still it, in contrast to the latter, is an inhibitor of the enzyme 5-enolpyruvylshikimate-3-phosphate-synthase in -i plants; see "The Resisiside Mapia!" 5. 646-649. with In the combinations that are claimed, the required quantities for application, as a rule, lie in the range from 20 to 1000, preferably from 20 to 800 g AR/ha of glyphosate. - For compounds (A2), also already known, made by engineering tolerant plants that are introduced into practice; iz 50 | see "LysKepire" 47. dagdapoa (1998), 5. 217 I; see also international application MO 92/00377, European patent applications ER-A-115673, ER- A-409815). "6 Examples of imidazolinone derivative herbicides (AZ) are (AZ.1) Ima zapur and its salts and ethers, (AZ.2) Imazetapur and its salts and ethers, (AZ.Z3) imazametabenz and its salts and ethers,

Gee! (AZ.4) Imazametabenz-methyl, (AZ.5) Imazamox and its salts and esters, where (AZ.6) Imazakhin and its salts and esters, for example, ammonium salt, (AZ.7) Imazapic (АС 263 222) and its salts and esters, for example, the ammonium salt. 60 Herbicides inhibit the enzyme acetolactate synthase (A! 5) and thus protein synthesis in plants; they are effective both when acting on leaves (contact action) and when applied to a pound, and show partial (partial) selectivity (selectivities) in cultures; see "Te Reviiside Mapzia!" 111 Eayop, Vgyivy Sgor Rgoiesiop

Sotspsii 1997, 5. 697-699 refer to (AZ.1), 5. 701-703 refer to (AZ.2), 5. 694-696 refer to (AZ.3) and (AZ.4), 5. 696-697 refer to (AZ.5), 5. 699-701 refer to (AZ.6) and 5. 5 and 6, referred to under AC 263 222 (refer to AZ.7). The amounts of herbicides used are usually between 0.001 and 2 kg

ArP/ha. In the combinations that are declared, they lie in the range from 10 to 200 g AR/ha.

Combinations with imidazolinones are used purposefully in corn cultures that are resistant to imidazolinones. Similar tolerant crops are already known in the European patent application

EP-A-0360750 describes, for example, the production of plants tolerant to inhibitors A! With (acetolactate synthase), by the method of selection or genetic engineering. The tolerance of plants to herbicides is caused by the increased content of A! 5 in plants. US patent IO5-A-5 198 599 describes plants tolerant to sulfonylureas and imidazolinones, which were bred by the method of selection.

Examples of PPO inhibitors (A4) are 70 (A4.1) Pyraflufen and its esters, such as pyraflufen-ethyl, (A4.2) Carfentrazone and its esters, such as carfentrazone-ethyl, (A4.3) Oxadiargyl, (A4 .4) Sulfentrazone, (A4.5) M/C9717 or СОА276854 -1-Allyloxycarbonyl-1-methylethyl ether 2-chloro-5-(3-methyl-2,6-dioxo-4-trifluoromethyl-3,6b-dihydro -2H-pyrimidin-1-yl)benzoic acid (known from the US patent O5-A-5 183 492).

These azoles are known as inhibitors of the protoporphyrinogen oxidase (PPO) enzyme in plants; see "Pe

Reswiiside Mapiai" 11 Edaiop, Vgyizp Stor Rgoiesiop Soitspsi! 1997, 5. 1048-1049 refer to (A4.1), 5. 191-193 refer to (A4.2), 5. 904-905 refer to (A4.3 ) and 5. 1126-1127 refer to (A4.4).

Tolerant plant cultures have already been described. Amounts of azoles that are introduced are, as a rule, in the range from 5 to 200 g AR/ha.

Some plants that are tolerant to PPO inhibitors are already known.

Examples of cyclohexanone (AB) derivative herbicides are: (ABY) Sethoxydim ("Reviside Mapa" 117 Ba, Vugyivy Sgor Rgoiesyop Soitspsii 1997 (hereinafter "RM", p. p. 1101-1103), i.e., (ED)-2-( 1-ethoxyimino-butyl)-5-(2-(ethylthio)propyl|-3-hydroxy-cyclohex-2-enone, o (A5.2) Cycloxidim (RM, p. 290-291), i.e., 2-( 1-ethoxyiminobutyl)-3-hydroxy-5-thian-3-ylcyclohex-2-enone, (AB.Z3) Clethodim (RM, p.250-251), i.e., 2-KE)-1-KE)-З3 -chlorallyoxyimino|-propyl)-5-(2-(ethylthio)propyl|-3-hydroxy-cyclohex-2-enone, (AB5.4) "Klefoxidim" or "VAZ 625 H" (see AO Spet. Mem Sotrotspa Chemiezhm Moii. 17.1999, 5. 26, published by ASKAMOMA) (-2-(1-(2--4-chlorophenoxy)-propoxyimino)butyl|-3-oxo-5-thion-3-yl-diclohex-1- enol), (AB.5) Tralkoxide (RM, p. 1211-1212), i.e., 3-2-I(11-(ethoxyimino)-propyl|-3-hydroxy-5--mesitylcyclohex-2-enone. -

Herbicides inhibit mitosis and thereby the synthesis of fatty acids in plants; this is especially true of foliar herbicides, and they exhibit partial crop selectivity(s). Consumption norms cm (used amounts) of herbicides usually lie between 0.2 and 1 kg AR/ha. In the combinations that are declared, they are usually in the range from 10 to 1000 g AR/ha. Combinations with cyclohexanediones are used purposefully in corn cultures that are resistant to cyclohexanediones. Similar tolerant cultures are already known. "

Examples of herbicides - derivatives of heteroarylphenoxyphenoxypropionic acid (Ab) are: (Ab.1) "Fenoxaprop-P" and its esters, such as "Fenoxa-prop-P-ethyl" ethyl ether (see RM, p. 519-520) - c (-(k)-2-I4-(6-chlorobenzoxazolyl-2-yloxy)phenoxy|propionic acid or its ethyl ester, is used as well as in the form of the racemate "Fenoxaprop-P" and its esters, such as ethyl ether, and /or "» (Ab.2) "Quizalofop-P" and its esters, such as ethyl or tefuryl ether, (see RM, p. 1089-1092) (-(K)-2-I4-(6-chloroquinoxaline -2-yloxy)phenoxy|propionic acid or its ethyl ester or tetrahydrofurfuryl ether, is also used in the form of the racemate "Quizalofop" and its esters; see - and also in the form of the special ester "Propachizafop" (compounds Ab.3), and/ or (Ab. 3) "Propakhizafop" (RM, p. 1021-1022), 2-isopropylidenaminooxyethyl ether of Khizalofop-R and/or (Ab. 4) "Fluazifop-R" and its esters, such as butyl ether, ( see RM, p. 556-557) and (-(k)-2-I4-(5-trifluoromethyl-pyrid-2-yloxy)phenoxy|-propion ova acid or its butyl ether), 1» 50 is also used in the form of racemate "Fluazifop" and its esters, and/or (Ab.5) "Haloxyfop-P" and its esters, such as methyl ether, (see RM, pp. 660-663) -. and ((k)-2-I4-(3-chloro-5-trifluoromethyl-pyrid-2-yloxy)phenoxy|propionic acid or its methyl ester), is also used in the form of racemate "Haloxyfop" and its esters, such as methyl or ethoyl ether, and/or (Ab.b) "Cyhalofop" and its esters, such as butyl ether, (see RM, p. 297-298) (-(k)-2-I4-(4-cyano -2-fluorophenoxy)phenoxy|propionic acid or its butyl ester), and/or o (Ab.7) "Clodinafop" and its esters, such as propargyl ether, (see RM, p.251-252) ime) ( -(k)-2-I4-(5-chloro-3-fluoro-pyrid-2-yloxy)phenoxy|propionic acid or its propargyl ester).

Herbicides (Ab) are known as inhibitors of fatty acid biosynthesis and are used in quantities of 5-500g 60 AR/ha. In the combinations that are declared, the amounts used can be partially reduced, for example, to 1-300 g AR/ha. Combinations of herbicides (Ab) are used purposefully in corn crops that are tolerant to herbicides; this is also observed in such cultures that are tolerant to herbicides - derivatives of cyclohexanedione (AB).

As a partner (B) in the combination, for example, the compounds of the following groups (B1)-(B4) are considered: 65 (81) Herbicides that are active both when acting on leaves and when applied to the soil, and which can be selectively used against weedy grass and dicotyledonous weeds, for example the following compounds (given data: "common name" and pages from the reference "Te Rezwiiside Mapia!"

Social media! 1997, abbreviated "RM"; (81.1) Cyanazine (RM, p. 280-283), that is, 2-(4-chloro-b-ethyl-amino-1,3,5-triazin-2-ylamino)-2-methyl-propionitrile, (81.2 ) Atrazine (RM, p. 55-57), that is, M-ethyl-M'-isopropyl-b-chloro-2,4-diamino-1,3,5-triazine, (81.3) Terbuthylazine (RM, p. 1168-1170), that is, M-ethyl-M'-tert-butyl-6-chloro-2,4-diamino-1,3,5-triazine, (81.4) Acetochlor (RM, p. 10-12), i.e., 2-chloro-M-(ethoxymethyl)-M-(2-ethyl-6-methylphenyl)-acetamide, (81.5) Metolachlor (RM, p.833-834), i.e., 2-chloro-M-(2 -ethyl-6-methylphenyl)-M-(2-methoxy-1-methylphenyl)acetamide, 70 (81.6) Alachlor (RM, p. 23-24), i.e., 2-chloro-M-(2,6-diethylphenyl )-M-(methoxymethyl)acetamide, (81.7) Terbutrin (RM, p. 1170-1172), i.e., M-(1,1-dimethylethyl)-M-ethyl-6-methylthio-2,4-diamino-1 ,3,5-triazine, (81.8) Benoxacor (RM, p. 102-103), i.e., 4-dichloro-acetyl-3,4-dihydro-3-methyl-2H-1,4-benzoxazine, (81.9) Nicosulfuron (RM, p. 877-879), that is, 2-(4,6-dimethoxypyrimidin-2-yl)-3-(3-dimethylcarbamoyl-2-pyridylsulfonyl)-urea, (81.10) Rimsulfuron (RM, p. 1095-1097), that is, 2-(4,6-dimethoxyp Irimidin-2-yl)-3-(3-ethylsulfonyl-2-pyridylsulfonyl)-urea, (81.11) Primsulfuron and its esters, such as methyl ether, (RM, p. 997-999), i.e., 2-I4, 6-bisidifluoromethoxy)-pyrimidin-2-ylcarbamoylsulfamoyl|benzoic acid or its methyl ester, (81.12) - Dimethenamid (RM, p. 409-410), i.e., 2-chloro-M-(2,4-dimethyl- 3-thienyl)-M-(2-methoxy-1-methylethyl)acetamide, (81.13) Flutiamide (VAU ROE 5043, flufenacet) (RM, p. 82-83), i.e. 4-Fluoro-M-isopropyl-2- (5-trifluoromethyl-1,3,4-thiadiazol-2-yloxy)acetanilide, (81.14) Sulcotrione (RM, p. 1124-1125), i.e., 2-(2-chloro-4-mesylbenzoyl)cyclohexane-1, 3-dione, (81.15) Simazine (RM, p. 1106-1108), i.e., b-chloro-M,M'-diethyl-2,4-diamino-1,3,5-triazine, Ha (81.16) Mesotrione , that is, 2-(4-mesyl-2-nitrobenzoyl)-cyclo-hexane-1,3-dione (2A1296, see MUUey Zsiepse zZosieiu oi Ategisa (MU55A) in M/Z5A Arbrzigasiv 1999, Va. 39, bZeye 65-66, 27ShMegp 130-132), and9) (81.17) Pentoxamide (RM, p. 1095-1097), i.e., 2-chloro-M-(2-ethoxyethyl)-M-(2-methyl) -1-phenyl-1-propenyl)acetamide (TKS-94, known from AS Spet. Mem Sotroshtspa

Chemiezh Moi.17 (1999), European patent application EP-A-206251, and in the case when the active substances from the group "h- (VI) are in the form of racemic mixtures, preferably also the active substance in the form of a pure or enriched active isomer , C (82) herbicides used selectively in corn against dicotyledonous weeds, for example, compounds: rch- (82.1) Pendimethalin (RM, p. 937-939), i.e., M-(1-ethylpropyl)-2,6 -dinitro-3,4-xylidine, (82.2) Pyridate (RM, p. 1064-1066), i.e., O-(6b-chloro-3-phenyl-pyridazin-4-yl) ether, Z-octyl ether with

Thiocarbonic acid, - (82.3) Iodosulfuron (proposed common name) and preferably methyl ether (see UUCHO 96/415371, i.e., 4-iodo-2-(4-methoxy-6-methyl-1,3,5-triazine- 2-ylcarbamoylsulfamoyl)benzoic acid or its methyl ester, known from the international application UUO 92/13845, "(82.4) Methosulam (RM, p.836-495), i.e., 2,6'-dichloro-5,7-dimethoxy- 3'-methyl-I1,2,4|triazolo|1,5a|pyrimidine-2-sulfoanilide, 8 s (82.5) Isoxaflutol (RM, p. 737-739), i.e., c (5-cyclopropyl-4-isoxazolyl )|2-methylsulfonyl-4--trifluoromethyl)-phenyl|methanone, "» (82.6) Metribuzin (RM, p.), i.e., 4-amino-6-tert-butyl-3-methylthio-1,2,4 -triazin-5(4H)-one, (82.7) Chloransulam and preferably methyl ether (RM, p. 165), that is,

3-Chloro-2-(5-ethoxy-7-fluoro-11,2,4|triazolo-|1,5-z|Ipyrimidin-2-ylsulfamido)benzoic acid or its methyl ester, (82.8) Flumetsulam ( RM, p. 573-574), that is, 2, di 6'-dichloro-5-methyl-|(1,2,4|triazolo-|1,5-3z|pyrimidine-2-sulfonanilide, -I (82.9 ) Linuron (RM, p. 751-753), i.e., 3-(3,4-dichlorophenyl)-1-methoxy-1-methyl-urea, (82.10) Florasulam, i.e., IM-(2,6-Difluorophenyl) )-8-fluoro-5-methoxy-11,2,4)gri-azolo-|1,5-z|pyrimidine-2-sulfonanilide, IOE-570, see - 7 eivspgii RIA. Kgapki RYAZsSptsi, Zopaetgriak KhMI, 527-534 81 1998), (82.11) Isoxachlorotol, i.e., (4-chloro-2-(methylsulfonyl)phenyl)(5-cyclo-propyl-4-isoxazolyl)-ketone, (European application for patent EP-A-470856) and in the case when the active substances from group (B2) are in the form of racemic mixtures, preferably also the active substance in the form of a pure or enriched active isomer,

F, (83) herbicides, which are herbicides with an effect on the leaves and with an effect on the soil and can be selectively used in corn, mainly against dicotyledonous weedy plants, for example, compounds: (83.1) Bromoxynil (RM, p. 149-151), that is, 3,5-dibromo-4-hydroxybenzonitrile, in (83.2) Dicamba (RM, p. 356-357), that is, 3,6-dichloro-o-anisic acid and its salts, (83.3 ) 2,4-O (RM, p.323-327), i.e., 2,4-dichlorophenoxyacetic acid and its salts and esters, (83.4) Clopyralid (RM, p.260-263), i.e., 3,6- dichloro-2-pyridinecarboxylic acid and its salts and esters, (83.5) Prosulfuron (RM p. 1041-1043), i.e., 1-(4-methoxy-b6-methyl-1,3,5-triazin-2-yl) -3-(2-(3,3,3-trifluoropropyl)-phenylsulfonyl|urea, 65 (83.6) Thifensulfuron and its ethers, mainly methyl ether (RM, p. 1188-1190), i.e., 3-ShSHK4-methoxy- b-methyl-1,3,5-triazin-2-yl)amino|carbonyl|-amino|sulfonyl|-2-thiophenecarboxylic acid or its methyl ester, (83.7) Carfentrazone and its salts and esters, mainly ethyl ether (PM , p.191-193), that is, 2-chloro- 3-(2-chloro-5-(4-difluoromethyl-4,5-dihydro-3-methyl-5-oxo-1H-1,2,4-triazol-1-yl)-4-fluorophenyl|propionic

The acid or its ethyl ether, while combinations with compounds (A4.2), according to the definition, do not represent herbicidal combinations of different herbicidal active substances and are thus excluded, (83.8) GAV271272 (-trisulfuron, SA Code. Mo142469-14- 5; see AOS Spegp. Mem Sotrotspa Kemiem, Moi!.17, 1999, 5.24, issued by ASKAMOMA, i.e.

IM-((4-methoxy-b6-trifluoromethyl-1,3,5-triazin-2-yl)amino|carbonyl|-2(trifluoromethyl)benzenesulfamide, and 70 (83.9) MSRA (RM, p. 767-769) , i.e., (4-chloro-2-methylphenoxy)acetic acid and its salts and esters, (83.10) Halosulfuron and its esters, such as methyl ether (RM, p.657-659), i.e., methyl ether

Z-chloro-5-(4,6-dimethoxypyrimidin-2-ylcarbamoyl-sulfamoyl)-1-methylpyrazole-4-carboxylic acid, also in the form of its salt, (83.11) Diflufenzopur (VABE 654 (0/8) H (RM, p.81-82), i.e., 2-(1-(4-(3,5-difluorophenyl)semicarbazoniethyl)-nicotinic acid and its salts, (83.12) Sulfosulfuron (RM, p.1130-1131), that is, 1--4,6-dimethoxypyrimidin-2-yl)-3-(2-ethylsulfonylimidazoi|1,2-a|pyridin-3-ylsulfonyl)-urea, and in the case when active substances from the group (BZ) are in the form of racemic mixtures, preferably also the active substance in the form of a pure or enriched active isomer.

In the case of active substances based on carboxylic acids or other salts and ester-forming active substances, the name of the herbicide should in general, due to the general name of the acid, also contain salts and ethers, preferably ordinary commercial salts and ethers, in particular, commonly used ready-made forms of the active substance.

The amounts of herbicides (B) used can vary greatly from herbicide to herbicide. The following limits can be named as a rough approximation of real values:

For compounds (80): 1-3000 g AR/ha, preferably 5-2000, see data for the group of compounds (A))

For compounds (B1): 0.1-5000g AR/ha, preferably 1-5000g AR/ha, and)

For compounds (82): 0.1-5000g AR/ha, preferably 1-3000g AR/ha,

For compounds (83): 0.1-5000g AR/ha, preferably 1-3000g AR/ha.

In some cases, the following applied quantities (consumption rates) in g AR/ha are preferable: "- zo (81.1)-(81.8) 100-5000 g, preferably 200-4000, especially preferably 3000-3500 (81.9)-(81.11) 0 ,1-120, preferably 200-4000, especially preferably 1-90, - (81.12) 50-5000, preferably 1000-4000, especially preferably 3000-3500, M (VIZ) 100-2000, preferably 2000-1500, especially preferably 300-1200, (81.14) 50-1000, preferably 100-600, especially preferably 200-3500, c (81.15) 1000-5000, preferably 200-4000, especially preferably 3000-3500, i- (81.16) 10-500, preferably 25-300, especially preferably 50-200, (81.17) 5-1500, preferably 10-1000, especially preferably 200-800, (82.1) 100-3000, preferably 200-2500, especially preferably 300-2000, (82.2) 100-2500, preferably 200-2000, especially preferably 300-1500, « (82.3) 0.1-100, preferably 0.2-20, especially preferably 0.5-15, with c (82.4) 1-200, preferably 5-150, especially preferably 10-100, . (82.5) 5-300, preferably 10-200, especially preferably 20-150, and? (82.6) 10-1500, preferably 25-1000, especially preferably 50-800, (82.7) 2-200, preferably 2.5-100, especially preferably 5-80, (82.8) 5-500, preferably 10-300, especially preferably 20-200, -I (82.9) 50-2500, preferably 100-2000, especially preferably 200-1000, (82.10) 0.5-100, preferably 1-20, especially preferably 3-15, ю (82.11) 5-300, preferably 110-200, especially preferably 200-150, -I (83.1) 50-1000, preferably 100-600, especially preferably 200-500, (83.2) 5-2500, preferably 100-2000, especially preferably 200 -1500, ve (83.3) 50-3000, preferably 100-2000, especially preferably 200-1500, as (83.4) 10-300, preferably 20-250, especially preferably 40-200, (83.5) 1-100, preferably 2 -70, especially preferably 5-50, (83.6) 0.5-100, preferably 1-50, especially preferably 2-40, (83.7) 1-250, preferably 5-120, especially preferably 10-100, (83.8) 1-200, preferably 5-150, especially preferably 10-120,

F) (83.9) 50-3000, preferably 100-2000, especially preferably 200-1500, ka (83.10) 1-200, preferably 5-150, especially preferably 10-50, (83.11) 5-1000, preferably 10-500 , especially preferably 20-80, in (83.12) 1-150, preferably 5-100, especially preferably 5-80,

Quantitative ratios of compounds (A) and (B) are taken from the above applied amounts for individual substances, and the following quantitative ratios are of particular interest: (A): (B) in the range from 18000:1 to 1:5000, preferably from 2000:1 up to 1:1000, especially preferably from 200:1 to 1:100, 65 (A):(80) in the range from 1000:1 to 1:400, preferably from 400:1 to 1:400, especially preferably from 200: 1 to 1:200,

(AT):(B1) in the range from 1500:1 to 1:300, preferably from 400:1 to 1:250, especially preferably from 200:1 to 1:100, (A1):(82) in the range from 10000 :1 to 1:300, preferably from 1500:1 to 1:250, especially preferably from 1000:1 to 1:100, quite preferably from 200:1 to 1:100, (A1):(83) within 2000 :1 to 1:300, preferably from 1500:1 to 1:250, especially preferably from 200:1 to 1:100, (A2):(B1) in the range from 2500:1 to 1:100, preferably from 20001 to 1 :50, especially preferably 300 1 to 1:20, 70 (A2):(82) in the range from 18000:1 to 1:100, preferably from 20001 to 1:50, especially preferably from 300:1 to 1:20, (A2):(83) in the range from 3000:1 to 1:100, preferably from 20001 to 1:50, especially preferably from 300:1 to 1:20, (AZ):(B1) in the range from 1000:1 up to 1:1000, preferably from 200:1 to 1:500, especially preferably from 100:1 to 1:200," (AZ):(82) in the range from 5000:1 to 1:1000, preferably from 800:1 up to 1:500, especially preferably from 200:1 to 1:500, quite preferably from 100:1 to 1:200, (AZ):(83) in the range from 500:1 to 1:800, preferably from 200:1 to 1:500, Fr sour cream preferably from 100:1 to 1:200, (A4):(B1) in the range from 1000:1 to 1:5000, preferably from 200:1 to 1:1000, especially preferably from 100:1 to 1:250, (A4):(82) in the range from 10000:1 to 1:5000, preferably from 2000:1 to 1:1000, especially preferably from 1000:1 to 1:400, quite preferably from 500:1 to 1:250, ( A4):(83) in the range from 1000:1 to 1:2000, preferably from 200:1 to 1:1000, especially preferably from 100:1 to 1:250, (AB):(B1) in the range from 1500 :1 to 1:1000, preferably from 1000:1 to 1:500, (8) especially preferably from 200:1 to 1:100, (AB5):(82) in the range from 10000:1 to 1:2000, preferably from 1000:1 to 1:500, especially preferably from 200:1 to 1:100, «- zo (AB):(83) in the range from 1500:1 to 1:1000, preferably from 1000:1 to 1:500 , especially preferably from 200:1 to 1:100, " (Ab):(B1) in the range from 200021 to 1:2000, preferably from 1000:1 to 1:1000, M especially preferably from 200:1 to 1:200 , (Ab):(82) in the range from 500021 to 1:2000, preferably from 2000:1 to 1:1000, with especially preferably from 200:1 to 1:100, і- (Ab):(83) in the range you d 1000:1 to 1:1000, preferably from 500:1 to 1:500, especially preferably from 100:1 to 1:100.

Of particular interest is the use of combinations (A1.1)4(81.1), (A1.1)4(81.2), (A1.1)4(81.3), (A1.1)4(81.4), (A1.1) 4(81.5), (А1.1)4(81.6), (А1.1)4(81.7), (А1.1)4(81.8), (А1.1)4(81.9), (А1.1 )4(81.10), in c (A1.1)4(81.11), (A1.1)4(81.12), (A1.1)4(81.13), (A1.1)4(81.14),

And (A1.1)4(81.15), (A1.1)4(81.16), (A1.1)4(81.17), and (A1.2)4(81.1), (A1.2)4(81.2 ), (А1.2)4(81.3), (А1.2)4(81.4), (А1.2)4(81.5), (А1.2)4(81.6), (А1.2)4(81.7 ), (А1.2)(81.8), (А1.2)4(81.9), (А1.2)4(81.10), (А1.2)4(81.11), (А1.2)4(81.12) , (A1.2)4(81.13), (A1.2)4(81.14), -And (A1.2)4(81.15), (A1.2)4(81.16), (A1.2)4( 81.17), (А1.1)4(82.1), (А1.1)4(82.2), (А1.1)4(82.3), (А1.1)4(82.4), (А1.1)4( 82.5), co (A1.1)4(82.6), (A1.1)4(82.7), (A1.1)4(82.8), (A1.1)4(82.9), -I (A1.1 )4(82.10), (А1.1)4(82.11), (А1.2)4(82.1), (А1.2)4(82.2), (А1.2)4(82.3), (А1.2 )4(82.4), (A1.2)4(82.5), and (A1.2)4(82.6), (A1.2)4(82.7), (A1.2)4(82.8), (A1. 2)4(82.9), shk (А1.2)4(82.10), (А12)4(82.11), (А1.1)4(83.1), (А1.1)4(83.2), (А1.1 )4(83.3), (А1.1)4(83.4), (А1.1)4(83.5), (А1.1)4(83.6), (А1.1)4(83.7), (А1.1 )4(83.8), (A1.1)4(83.9), 5B (A1.1)4(83.10), (A1.1)4(83.11), (A1.1)4(83.12), (A1. 1)4(83.13), (A1.2)4(83.1), (A1.2)4(83.2), (A1.2)4(83.3), (A1.2)4(83.4), (A1. 2)4(83.5),

F) (А1.2)4(83.6), (А1.2)4(83.7), (А1.2)4(83.8), (А1.2)4(83.9), ka (А1.2)4( 83.10), (A1.2)4(83.11), (A1.2)4(83.12), (A1.2)4(83.13), (A2.2)4(81.1), (A2.2)4( 81.2), (A2.2)4(81.3), (A2.2)4(81.4), (A2.2)4(81.5), 60 (A2.2)4(81.6), (A2.2)34 (81.7), (A2.2)(81.8), (A2.2)4(81.9), (A2.2)4(81.10), (A2.2)4(81.11), (A2.2)34( 81.12), (A2.2)4(81.13), (A2.2)45(81.14), (A2.2)4(81.15), (A2.2)4(81.16), (A2.2)4( 81.17), (A2.2)4(82.1), (A2.2)4(82.2), (A2.2)4(82.3), (A2.2)4(82.4), (A2.2)4( 82.5)), (A2.2)4(82.6), (A2.2)4(82.7), (A2.2)4(82.8), (A2.2)4(82.9), 65 (A2.2) 4(82.10), (A2.2)4(82.11), (A2.2)4(83.1), (A2.2)4(83.2), (A2.2)44(83.3), (A2.2) 4(83.4), (A2.2)(83.5),

(A2.2)4(83.6), (A2.2)4(83.7), (A2.2)44(83.8), (A2.2)(B83.9), (A2.2)4(83.10) , (A2.2)4(83.11), (A2.2)4(83.12), (A2.2)(83.13).

In the case of a combination of compound (A) with one or more compounds (BO), it is, according to the definition, a combination of two or more compounds from group (A). Due to broad-spectrum herbicides (A), such a combination is envisaged that transgenic plants or mutants are resistant in all directions to different herbicides (A).

Similar resistances in all directions (Kreutz resistances) are already known for transgenic plants; see international application UUO-A-98/20144. 70 In some cases, it makes sense to combine one or more compounds (A) with several compounds (B), preferably from classes (B1), (B2) and (83).

In addition, the claimed combinations can be used together with other active substances from the group of substances that promote safety, fungicides, insecticides and plant growth regulators or from the group of conventional plant protection additives and auxiliary compounds. Additives are, for example, fertilizers or /5 dyes.

Herbicidal combinations of one or more compounds (A) with one or more compounds of group (B1) or (82) or (83) are preferred.

In addition, combinations of herbicides from one or more compounds (A), for example, (A1.2)(A2.2), preferably compounds (A) with one or more compounds (B) according to the scheme: (A)(B1) are preferred )4(B2), (А)Ж(В1)К(ВЗ), (МУКВ2)НВЗ).

At the same time, according to the invention, such combinations can also be made, to which one or more other active substances of a different structure (Active substance (C)) are added, such as, for example, (A)H(B1)(C), ( A) HB2UKS) or (UNIV) KS), (DNIV K(B2 KS) or (DUNV KV KS) or (A)HB2uUKVZIX).

For combinations of the last aforementioned type with three or more active substances, the more favorable conditions explained below, primarily for the double combinations that are claimed, are also valid in the first place, since the double combinations that are claimed are contained in them, and the said combinations have (8 ) is directly related to double combinations.

As an active substance (C), those that have a preserving effect on corn crops are preferred, especially substances that promote preservation, which in combination with herbicides (B) reduce or eliminate the phytotoxic side effect of herbicides in corn plants.

Of particular interest is also the application of combinations, which is claimed, with one herbicide from the group - (A), preferably (A1.2) or (A2.2), especially (A1.2), and with one or more herbicides, preferably with one M herbicide, from group (B1) cyanazine, acetochlor, alachlor, terbutrin, benoxacor, fluthiamide, sulcotrione, mesotrione and pentoxamide or c (82) pendimethalin, iodosulfuron, methosulam, isoxaflutol, metribuzin, cloransulam, i-flumetsulam and also florasulam and isoxachlortol or (83) bromoxynil, clopirapid, carfentrazone and Gar271272 as well as halosulfuron, diflufenzopur and sulfosulfuron or herbicides from several groups (B1) - (83). "

Combinations of the corresponding components (A) with one or more herbicides from the group pl») with (VT), (82) or (83) are the best. . In addition, the best combinations are (А)Ж(В14(82), (А)Н(В1У4(83) or (А)Н(В2)4(83. and?) ) exhibit excellent herbicidal activity against a wide range of economically important monocotyledonous and dicotyledonous weedy plants.

Those that give sprouts from rhizomes, root stumps or other long-lived organs are also well destroyed with the help of active substances. At the same time, it is equally important whether the substances are applied before sowing, before germination (during the period of swelling) or after germination. It is better to use in the post-emergence method or in the early period after sowing, where - before the seedlings. -I It is worth mentioning separately, for example, some representatives of monocotyledonous and dicotyledonous flora of weeds, which can be controlled with the help of compounds that are declared, at the same time, due to the name, restrictions should not be imposed on certain species. as Monocotyledonous weeds are strongly affected, for example, Espipospisa spp., Zeiagia spp., Oidnagia spp.,

Vgaspiyivia spp., Rapisit spp., Adgorugop spp., species of wild grasses and Zogupyit spp., as well as Amepa spp.,

AIoresigiz group, and Supodop group, I oiisht group, Riaagiz group, Roa group, as well as Suregiz and Itregaiia species.

For dicotyledonous weeds, the spectrum of action is extended to species such as Speporodit spp., Atagapipis spp., Zoiiapit spp., YuOaishga spp., Abshiyop spp., Irotoea spp., Roiiudopyt spp., Hapipisht spp., Z(eiYagia Ltd.,

F) Cospia Co., Ltd. and Misoia sr., as well as SPpguzapipetit sr., Mapisagia sr., Megopisa sr., Apipetiv sr., TPIazri ka sr., Saiisht sr., Iatisht sr., RIagryz ovr. Bida Co., Ltd., Zipariv Co., Ltd., SyrzeMya Co., Ltd., Sigvisht. egrr.,

Sopumoimtsiz zrr., Kiteh and Agietivia. 60 If the claimed compounds are applied to the soil surface before germination, then either the sprouting weed seedlings are completely suppressed, or the weeds grow to the stage of the sprouted leaf, but then still stop growing and, ultimately, completely die off after three to four weeks.

When the active substances are applied to the green parts of the plants according to the post-emergence method, a sharp stoppage of growth also occurs very quickly after treatment, and the weedy plants stop at the growth stage, which is at the 65th point, which corresponds to the time of application, and after a certain time completely die off, and in this way, the competition of weeds that harm cultivated plants is eliminated very early and for a long time.

Herbicidal means, which are declared, in comparison with individual preparations, differ in herbicidal action, which occurs faster and lasts longer. The resistance of active substances to rain in the combinations that are claimed is usually sufficient. The gain in weight is especially beneficial: effective and used in combination dosages of compounds (A) and (B) can be set quite small, and at the same time their effect on the soil is optimal.

Thus, their use is possible not only in sensual cultures, but combinations based on water should be avoided in practice. Due to the combinations of active substances that are declared, it is possible to significantly reduce the required amounts of active substances.

When herbicides of type (A)X(B) are used together, a non-additive effect is revealed (synergistic effect - /o binergism). At the same time, the effectiveness of the combination is higher than the effectiveness of the expected total effect of individual herbicides. Synergistic effects allow for reduced application rates, control of a wide range of weeds and grasses, allow for faster onset and longer duration of action of herbicides, allow for enhanced weed control with only one or fewer applications, and also allow expand the time frame of possible use. Partly due to the use of /5 agent in plant cultures, the amount of harmful ingredients, such as nitrogen or butyric acid, is also reduced.

The mentioned properties and advantages are necessary in the practical fight against weeds, in order to free agricultural crops from unwanted competitive plants and thereby quantitatively and qualitatively guarantee the harvest at the proper level and/or increase it. Thanks to the specified new combinations, the norms of technical standards regarding the described properties are clearly exceeded.

Despite the fact that the claimed compounds exhibit excellent herbicidal activity against monocotyledonous and dicotyledonous weeds, tolerant or Kreutz-tolerant corn plants are damaged only to a minor degree or not at all.

Moreover, the claimed agents sometimes show excellent growth-regulating properties in corn plants. They intervene in the plant's own metabolism in a regulatory way and can be used for separate effects on the constituent parts of plants. In addition, they are also suitable for general control and inhibition of unwanted vegetative growth, without causing the plants to die. and)

Inhibition of vegetative growth plays a large role in many monocotyledonous and dicotyledonous crops, because growth can thereby be reduced or can be completely averted.

On the basis of their herbicidal and plant growth-regulating properties, the products are used for the control of harmful plants in known tolerant or Kreuz-tolerant corn crops or in not yet developed tolerant or genetically modified corn crops. Transgenic plants, as a rule, differ - especially in advantageous properties, so, along with resistance to the means that are declared, they possess, for example, resistance to plant diseases or plant pathogens, such as certain insecticides or microorganisms, for example, fungi, bacteria or viruses. Other distinctive properties of c refer, for example, to fruits (harvest) - to their quantity, quality, ability to preserve, composition and special ingredients. Thus, transgenic plants with increased oil content or increased quality, for example, with a different composition of fatty acids in fruits, are known.

The usual ways of obtaining new plants, which, in comparison with previously known ones, have modified properties, consist, for example, in the classical method of selection and in the production of mutants. Alternatively, new plants with changed properties can be bred using a genetic engineering method (see, for example, European patent applications EP-A-0221044, EP-A-0131624). In many cases, for example, genetic engineering changes in plant cultures with the aim of modifying the starch synthesized in plants are described (for example, "from" international applications UUHO 92/11376, UHO 92/14827, MO 91/198061, - transgenic plant cultures that have resistance to other herbicides, for example, bullphonylurea (European patent application EP-A-0257993, US patent 05-A-50136591, -I - transgenic plant cultures that have the ability to make Thuringian toxins (Vi-toxins), which plants make resistant to specified pests (European patent applications EP-A-0142924, EU EP-A-01932591, -I - transgenic plant cultures with a modified composition of fatty acids, international application UUO 91/139721.

Numerous molecular biological technologies, with the help of which new transgenic plants with changed properties can be obtained, are known in principle; see, for example, Zatrgook ei ai., 1989, MoiIesshag as Siopipu, A Iarogaigu Mapia!i, 2. Ai. Soy Zrgipda Nagrog I aroghaiogu Rgez5z, Soy Zrgipd Nagrog, MM; or

MUippasKeg "Sepe pa Kiope7 MSN MUeippeit 2. Ashiade 1996 or SpPgivoyoi, "Tgepaz ip Riapi Zsiepse" 1 (1996)423-431).

For similar genetic engineering manipulations, nucleic acid molecules can be embedded in. plasmids that enable mutagenesis or sequence change due to recombination of DNA sequences. According to (F), with the help of the above-mentioned standard methods, for example, base exchanges can occur, parts of sequences can be removed or natural or synthetic sequences can be added. To bind DNA fragments one under the other, adapters or linkers can be connected to the fragments. 60 Production of plant cells with reduced activity of the gene product can be achieved, for example, due to the expression of at least one appropriate antisense RNA, one sense RNA to achieve a cosuppressive effect, or the expression of at least one suitably constructed ribosome, which is specifically cleaves the transcript of the aforementioned gene product.

For this, DNA molecules that include the general coding sequence of the 65 gene product, including randomly present flanking sequences, as well as DNA molecules that include only parts of the coding sequence can be used, while the specified parts must be of sufficient length to cause antisense in cells effect. It is also possible to use DNA sequences that have a high degree of homology to the coding sequences of the gene product, but are not completely identical.

During the expression of nucleic acid molecules in plants, the synthesized protein can be localized in any compartment. In order to achieve localization in a defined compartment, coding sequences can be linked, for example, to DNA sequences that guarantee localization in a defined compartment. Similar sequences are known to specialists | see, for example, Vgatsp ei ai., EMVO 4. 11 (1992), 3219-3227; MoTseg eyi ai., Rgos. May). Aside. All together. OBA 85 (1988), 846-850; Zoppemaiia ei a/!., RiIapi U. 1 (1991), 95-106).

Transgenic plant cells can be regenerated using known technologies into whole plants. With 7/0 transgenic plants, we can basically talk about plants of any kind, that is, both monocotyledonous and dicotyledonous plants.

Thus, transgenic plants can be obtained that exhibit altered properties due to overexpression, suppression, or inhibition of homologous ("natural") genes or gene sequences or expression of heterologous (foreign) genes or gene sequences.

In connection with this subject of the invention, there is also a method of combating unwanted plant growth in tolerant cereal crops, which differs in that one or more herbicides of type (A) with one or more herbicides of type (B) are applied to weedy plants, parts of these plants or on the treated surface.

The subject of the invention are also new combinations of compounds (A) ZK(B) and herbicides containing these combinations.

The combinations of active substances that are claimed can also be in the form of mixed compositions of two Components, in some cases with other active substances, additives and/or conventional auxiliaries, said mixed compositions are then diluted in the usual way with water and used, or the combinations that are claimed, are produced in the form of so-called tank (tanker) mixtures using a general dilution of separately composed or partially separately composed components.

Compounds (A) and (B) or their combinations can be composed in different ways, depending on which biological or physicochemical parameters are set. As general possibilities for (type of) compositions are considered, for example: powder for spraying (MUR), emulsifiable concentrates (EC), aqueous solutions (51), and) emulsions (EMU), such as emulsions "oil in water" or "water in oil" sprayable solutions or emulsions, oil-based or water-based dispersions, suspoemulsions, powdered (dusty) agents (OR), etching agents, granulates for application in a pound or for scattering or water-dispersible granules (MUR), "-

Mi M compositions, microcapsules or waxes.

Separate types of compositions are in principle known and described, for example, in: MUUippasKeg-Koispieg, "Spetizspe -

Tesppoiodieye"? Vapa 7, S. Naiveg Mepad Mipspep, 4. Ashyi. 1986; map of MaiYiKeprigu, "Reziiside Rogtshiiaiopv", M

Mags! OekKeg M.U., 1973; K. Magpepv, "Zrgau Oguipd Naparsok", Z'YA Ed. 1979, S. Soodymip TSI. And opdop.

Necessary auxiliaries such as inert materials, surfactants, solvents and other additives are also known and described, for example; in; UMaikipz, "Napadrsok oi Ipsesiiside Bizi Oiisepiv apa Sagtiegv", pa -

Ea., Oapapa Vookv, Saiduei! M.9U.; N.m.OiIrpep, "Ipigodisiop o SiIau Sopoiiy Spetivigu", 2794 Ed, U. Mieu b Bopv,

M.M. Magedep, "ZoiYimepi diyide", 274 Edy., Ipiegvsiepse, M.M. 1950; MeSiispeop'v, "Oefegdepiv apa Etiiiviyegv

Apptsuai!" MOSS RybBiI. Sogr., Kidedejooi M.).; Zivieu apa MUsod, "Epsusioredia oi bZypase Asiime Adepiv", "

Riri sings. Co. Ips., M.M. 1964; 5spbpieiai, ,geplPaspepakime AgPuiepokhidadatskie", MUizv. Mepgiadzdezeivsnaiy, eiShNdaga 1976; M/ippaskeg-Koaspieg, "Spetivspe Tesppoiodie", Vapa 7, S. Nayzeg Megiad Moipspep, 4. Atsii. 1986. - c On the basis of the indicated compositions can also be obtained combinations with other substances that have h pesticidal activity, such as, for example, other herbicides, fungicides or insecticides, as well as with » substances that promote the preservation, fertilizers and/or plant growth regulators, for example, in the form of a solid composition or tanker (tank ) mixtures.

Powders for spraying (wettable powders) are preparations that are evenly dispersed in water - which, along with the active substance, in addition to a diluent and an inert substance, also contain surface-active substances of the ionic and non-ionic type (wetting agents, dispersants), for example, polyoxyethylated alkylphenols, polyoxyethylated fatty alcohols or fatty amines, alkanesulfonates or alkylbenzenesulfonates, sodium salt - lignin-sulfonic acids, sodium salt of 2,2'-dinaphthylmethane-6,6'-disulfonic acids or sodium oleoylmethyltauric acid.

Emulsifiable concentrates are obtained by dissolving the active substance in an organic solvent, for example, with butanol, cyclohexanone, dimethylformamide, or xylene, as well as in high-boiling aromatic compounds or hydrocarbons with the addition of one or more ionic or nonionic surfactants (emulsifiers). Emulsifiers can be used, for example: calcium salts of alkylarylsulfonic acids, such as calcium dodecylbenzenesulfonate, or nonionic emulsifiers, such as

Gee! polyglycol ethers of fatty acids, alkylarylpolyglycol ethers, polyglycol ethers of fatty alcohols, condensation products of propylene oxide-ethylene oxide mixtures, alkylpropyl ethers, sorbitan-fatty acid esters, where polyoxyethylene sorbitan-fatty acid esters or polyoxyethylene sorbitan esters.

Powdered agents are obtained by grinding the active substance with finely divided solids such as talc, natural clays such as kaolin, bentonite and pyrophyllite, or diatomaceous earth. Granules can be obtained either by spraying the active substance with the help of a nozzle onto a granular inert material capable of adsorption, or by applying concentrates of active substances with the help of adhesives, for example, polyvinyl alcohol, sodium salt of polyacrylic acid, or also with the help of mineral oils on the surface of carriers, such as sand, kaolinites, or on the surface of granulated b5 inert material. Suitable active substances can also be granulated by the usual method for obtaining granulated fertilizers by the T method, if desired, in a mixture with fertilizers. Water-dispersible granulates are usually obtained by methods such as spray drying, fluidized bed granulation, plate granulation, mixing in high-speed mixers, and extrusion without solid inert material.

Agrochemical compositions contain, as a rule, from 0.1 to 99% by weight, in particular from 2 to 95% by weight of active substances of types A and/or B, while, depending on the type of composition, the following concentrations are usually used. In powders for spraying, the concentration of active substances is, for example, from approximately 10 to OBwag.9o, the balance up to 1OOwag.9o consists of ordinary components. In the case of emulsifying concentrates, the concentration of active substances can be, for example, from 5 to 8Ovag.9r.

Powder-like compositions mostly contain from 5 to 2O0wag.9o of the active substance, solutions that are sprayed, approximately from 0.2 to 25wag.9o of the active substance.

In the case of granules, such as dispersible granules, the content of the active substance depends on whether the active compound is in liquid or solid form and which granulating agents and fillers are used. As a rule, for water-dispersible granules, the content of the active substance is between 10 and

ZOvag.Oo.

In addition, said compositions with active substances in some cases contain currently conventional agents that improve adhesion, wetting agents, dispersing agents, emulsifiers, preservatives, agents that protect against freezing, and solvents, fillers, dyes and carriers, antifoams, substances, that prevent evaporation, and agents that affect the pH value and viscosity.

For example, it is known that the action of glufosinate ammonium (A1.2), as well as its I -enantiomers, can become more effective due to surface-active substances, mainly due to wetting agents from a series of sulfates of alkyl-polyglycol ethers, which contain, for example , from 10 to 18 carbon atoms, and are used in the form of their salts with alkali metals or ammonium salts, as well as in the form of magnesium salts, for example, such as sodium salts of sulfates of mixed ethers of fatty alcohols with diglycols (bSeparo! KO, Noespz|); see European patent applications EP-A-0476555, EP-A-0336151 or US patent I5-A-4 400 196, as well as Rgos. EMUK5 sch ov Tomorrow. "Rasiogz AbPesiipu Negrisida! Asnmyu apa zZeiesiimnu"» 227-232 (1988). In addition, alkylpolyglycol ether sulfates, as well as penetration enhancers and enhancers, (8) are known to be useful for a number of other herbicides, including imidazolinone herbicides, see European patent application EP-A-0502014.

For use, the usual commercial forms of the presented compositions are in some cases diluted - in the usual way, for example, in the case of spray powders, emulsifying concentrates, dispersions and water-dispersible granules - with water. Powdered compositions, granulates placed in a pound, and granulates - which crumble, as well as solutions which are sprayed, are usually not further diluted before their use with other inert substances.

Active substances can be applied to plants, to parts of plants, to plant seeds or to cultivated surfaces (arable land), mainly to green plants or parts of plants and in some cases additionally to arable land.

Also possible is an application that involves the joint use of active substances in the form of tank mixes, whereby optimally prepared concentrated compositions of individual active substances are mixed together in a vessel with water, and the resulting spray mixture is used as a herbicide. "

The claimed general herbicidal combination of individual active substances (A) and (B) has an advantage from the point of view of ease of use, because the number of components is already in the correct ratio. each other. In addition, the auxiliary means in the composition are optimally matched to each other, while as a tank mix of different compositions may contain an undesirable combination of excipients.

А Examples of compositions of the general type a) The powder-like agent is obtained by mixing 1Ovag. parts of the active substance/mixture of active substances and -I Z9Ovag. parts of talc as an inert substance and crushing the resulting mixture in an impact mill. c) The powder, which is wettable and is easily dispersed in water, is obtained by mixing 25 wt. parts of the active substance/mixture of active substances from b4wag. parts of kaolin-retaining quartz as an inert substance, -I 1Ovag. parts of the potassium salt of lignin-sulfonic acid and yoga. parts of the sodium salt of oleoyl-methyl-taurine 5or Acids as a wetting and dispersing agent and by grinding the resulting mixture in a rod mill, weight c) Easily dispersible in water, the dispersion concentrate is obtained by mixing 2Ovag. parts of the active substance/mixture of active substances from bvag. parts of alkylphenol polyglycol ether (Top X 207), Weight. parts of isotridecanol polyglycol ether (8 EC) and 71 wt. parts of paraffinic mineral oil (boiling range, for example, from about 255 to 2772) and grinding the resulting mixture in a ball mill to a fineness of less than 5 microns. a) The emulsifying concentrate is obtained from 15 kg. parts of the active substance/mixture of active substances, 75 kg. iF) parts of cyclohexanone as a solvent and 1Ovag. parts of oxyethylated nonylphenol as an emulsifier, which e) Water-dispersible granulate is obtained by mixing 75 wt. parts of the active substance/mixture of active substances, in 1Ovag. parts of the calcium salt of lignin-sulfonic acid, 5 kg. parts of sodium lauryl sulfate,

Weight parts of polyvinyl alcohol and 7 wt. parts of kaolin, by grinding the resulting mixture in a rod mill and granulating the powder in a vortex layer using spraying with water as a granulating liquid.

І) The water-dispersible granulate is obtained in such a way that 25 wt. parts of the active substance/mixture of active substances, 5 kg. parts of the sodium salt of 2,2'-dinaphthylmethane-6b,6b'-disulfonic acid, 2 wt. parts of the sodium salt of oleoyl-methyl-tauric acid,

Ziwag parts of polyvinyl alcohol, 17 kg. parts of calcium carbonate and

Bovage parts of water on a colloidal mill and pre-crushed, then ground on a bead mill, the suspension obtained in this way is sprayed in a sprayer using a nozzle and dried. 70 Biological examples 1. Effect on weeds before germination

Seeds or rhizomes of monocotyledonous and dicotyledonous weed plants are planted in cardboard pots in sandy loam soil and covered with earth. Means prepared earlier in the form of concentrated aqueous solutions, wettable powders, or emulsion concentrates are then applied in the form of an aqueous solution, /5 bus suspension or emulsion in water, the amount of which is taken at the rate of 600-80Ol/ha, in various dosages on the surface land After processing, the pots are placed in a greenhouse and kept in conditions favorable for the growth of weeds. Visual observation of damage to plants or seedlings (shoots) is done after germination of the tested plants 3-4 weeks after the start of the experiment in comparison with untreated control plants. As the results of the observation show, the claimed means show high herbicidal efficiency in the pre-emergent period against a wide range of weedy cereals and grasses.

At the same time, often for the combinations that are declared, efficiencies are observed that exceed the formal sum of efficiencies when herbicides are used separately (-synergistic action).

When the observed efficacy values exceed the formal sum of the values in experiments in which the active substances are used separately, then they also exceed the expected Kolby value, which is calculated according to the following formula and is also considered as evidence of synergism (see 5.K SoiiBu, in M/eeaz 15 (1967) 8. 20-221; i)

EAzhV-(А.В/100)

At the same time, the following designations are used: A, B - The effectiveness of active substances A, respectively, B in 95 at a or 5 in g AR/ha. "--

E:- expected value in 9o at av in g AR/ha.

The values observed in the experiments indicate that at suitable low doses, the effectiveness of C combinations is higher than the expected values according to Kolby. ch 2. Action on weeds in the post-emergence period

Seeds or shoots of rhizomes of monocotyledonous and dicotyledonous weedy plants are planted in cardboard pots in

A sandy loam pound, covered with earth and germinated in a greenhouse under favorable conditions for growth. Three weeks after planting, experimental plants at the stage of the third leaf are treated with the means that are declared.

Means that are applied, prepared in the form of powders for spraying or emulsion concentrates, in different dosages are sprayed with water, the amount of which is taken at the rate of 600-800 l/ha, on the green parts of plants.

Approximately 3-4 weeks after the experimental plants have been in the greenhouse under optimal conditions for growth, the effect of the drugs is assessed visually in comparison with untreated control plants. Means that are applied, in the post-emergence period, also show high herbicidal activity against a wide and spectrum of economically important weedy cereals and weedy plants. At the same time, there are often observed "" effectiveness of combinations, which are declared, which exceed the formal sum of effectiveness when using herbicides individually.

The observed values in the experiments indicate that at suitable low doses the efficacy of the -i combinations lies above the expected Kolby values (see the estimate in Example 1). 3. Herbicidal action and compatibility with plant crops (field experiment) where plants of transgenic corn crops, with resistance to one or more herbicides (A), -I were grown together with typical weedy plants in an open pound on plots measuring 2 x 5 m in 5 about natural conditions of open ground; alternatively, when growing corn plants, natural overgrowth with weeds was established. Treatment with the claimed means and separate treatment in the control experiment using only one of the components of the active substances were done in parallel under standard conditions, using a special device for spraying (on parcels) with a water consumption of 200-300 liters per hectare, according to the scheme from Table 1, that is, in the periods before sowing - before germination, after sowing - before germination or after germination at an early, middle or late stage. o yu re NIY ET i PO POLO NO

TUE MON POLO MEANS NOYA POLO PO no on 1 b5 Follow-up 00001111 " (A) (c)

I in her ves yavna her in in 111 on her ganei11111111jan111і1 janvan jan to nn nn nanny) 11 anger nn 111ne 5 11111111

At intervals of 2, 4, 6 and 8 weeks after application, the herbicidal efficacy of active substances or mixtures of active substances was assessed visually on treated plots in comparison with control untreated plots. At the same time, damage and development of all aerial parts of plants were taken into account. The assessment was made on a 20 percent scale (10095 efficiency - all plants died; 5095 efficiency - 5095 plants and green parts of plants died; 095 efficiency - no noticeable effect - as in the control plots). In each case, the scores for 4 parcels were averaged.

The comparison showed that the claimed combinations, in most cases, show greater, and in some cases significantly greater, effectiveness than the sum of the effectiveness of individual herbicides (E 7). c 25 Efficiencies during significant periods of observation time lie above the expected values according to Kolby o (EU) (see explanation in example 1) and therefore indicate synergism. Corn plants, in contrast, are not damaged or slightly damaged by processing. Further results of the experiments are given in the following table.

Abbreviations used in the general case in the following tables: gAR/gram of active -- 30 substances (100905th active substance) per hectare "

ЭХ is the sum of herbicide effectiveness when herbicides are used individually

ES - expected value according to Colby (see explanation to table 1) - "Maize 11" - FI irepu-Iipk-Maize (maize), which is tolerant or resistant to ammonium glufosinate. 35 and - : (12) 200 2 o 8 unknown write M SHI xz bo Z zo 92 " vza. 71311161 (A1.2)4(8.3.2) 200-300 Z 9A(E-88) 75(EL- C) and we: WE Ne She: c

Abbreviations to table 2: ko 1)- Application at the 5-6 leaf stage -1 2)- Observation 11 days after application 3)- in Irepa-Hipk-Maiz - corn, which is resistant to glufosinate ammonium, i" 20 ( A1.2)- Ammonium glufosinate (83.2)- Dicamba - st

Active substance(s) Dose 1) g ARIha|Herbicidal efficiency? (96) vs| Damage at 95 on GI corn. at p.m

AND

Zoo o 72 va 2 400 11 69 82 5 bo boo 15 69 87 Z 1000 74 74 85 4 viyu |v 1030100001100 (A1.2)4(81.2) 20041500 32 oB(EC-89) | 87(Е-68) З 40041500 68 о7(ЕС-75) | B8 (EA-85) 4 b5

Abbreviations to table 3: 1)- Application at the stage of 2-4 leaves 2)- observation after 3 weeks after application (A1.2)- Glufosinate ammonium (81.2)- Atrazine

ASKKE- Adgorugop herep5

ZETMI- Zeiagia migidiv

AMAKE- Atagapiipiv geygoPyekhiv

Table 4

Herbicidal efficacy in a field experiment on corn

Active substance) |Dose 7!) g AR/ha Herbicidal efficiency?) (95) against ERNNI (Damage in 95 on corn C 00 45 (81.16) 50 bo 100 58 150 70 (A1.2)4(81.16) 30050 83 (EC-78) 10 zo0-100 95 (EC-tt) 10

Abbreviations to Table 4: 1)- Application at the 4th leaf stage 2)- Observation after b weeks after application (A1.2)- Glufosinate ammonium c (81.16)- Mesotrione

ERNNEY- Eirpogria. peiehorputsa o

Table 5

Herbicidal efficiency in a field experiment on corn

Active substance) Dose 7!) g AR/ha Damage in 95 on GI corn. Herbicidal efficiency?) 96 against Eirpogria pes(egorpuia " (A1.2) 400 bo 200 50 - 100 37 (8119 400 75 s 00 68 200 vo v. (A1.2)4(B1.14) 100-200 99( E A-97) 4004200 99 (E C-84)

Abbreviations to Table 5: "1) - Application at the stage of 6 leaves of sshh c 2) observation 44 days after application (A1.2) - Glufosinate ammonium h (81.14) - Sulcotrion and?

Table 6 - I Herbicidal efficiency in a field experiment on corn 7 Active substance(s)| Dose !) g AR/ha Herbicidal efficiency) (95) vs

Radorugop Ezshepisht GG oiisht tiykyogit -i (12) BOO 55 78 330 20 15 ve 200 1o about her in (A1.2)4(8.2.3) 33082.5 9Z(E S.-vV) OO(E 2-87 )

Abbreviations to table 6: 1)- entry at stage 2-4 of the sheet

GF) 2)- Observation 26 days after application (A1.2)- Glufosinate ammonium ko (82.3)-. Iodosulfuron-methyl 60

Table 7

Herbicidal efficacy in a field experiment on corn

Active substance) Dose 7!) gAR/ha Herbicidal effectiveness?) (95) vs

Rogishasa oiegasea 65 (A1.2) 450 50 50 00 48 43 tv) two (A1.2)4(8.1.5) zZo0-1680 o8(E 2-88) oB(EA-78) (vl) 2242 (A1 .2)4(8.1.1) Z002242 Vb(E-83) 93(E-88) 837 (A1.2)4(8.3.1) zoo-360 63 (EA-B8) bB(EA-60)

Abbreviations to table 7: 1)- Application at the 2-4 leaf stage 2)- Observation 28 days after application (A1.2)- Glufosinate ammonium (81.53- Metolachlor (83.1)- Bromoxynil

Table 8

Herbicidal efficacy in a field experiment on corn

Active substance) Dose )) g AR/ha Herbicidal efficiency?) (96) against Zogapyt Ppaierepze (A1.2) 500 53 00 15 (81.11) 20 93 10 v2 (A1.2)4(B1.11) 300-110 78 (EL-77)

Abbreviations to Table 8: c 1) - application at the stage of 4 leaves of He) 2) - observation 28 days after application (A1.2) - Glufosinate ammonium (B 1.11) - Primisulfuron-methyl h

Table 9 ch;E

Herbicidal effectiveness in a field experiment on corn in

Active substance) Dose !) g AR/ha Herbicidal efficiency?) (95) against Savzvia orishvitoia tyuyu sch 827 she nn zi i - (A1.T)H(B.2.1) 400-925 BB(E 1-60)

Abbreviations to table 9: 1)- application at the stage of the C leaf "2)- Observation 21 days after application (A1.2)- Glufosinate ammonium - with (82.1)- Pendimethalin. and?

Table 10

Herbicidal efficacy in a field experiment on corn - Active substance(s)) Dose 7/ g ha Herbicidal efficacy o) against Vgaspiagia riapiadipea

A (a) | Dose 7) g AR/ha IHerbi f ist?) (96) Vgasnpiagia riapiadi (A1.2) Г510)8) 70 ke 00 45 150 5 - тв) t5o iz 50 (A1.2)(В1.5) 15041500 oB (EA-75) - Abbreviation to Table 10: 1)- application at stage 2 of the leaf 2)- Observation 28 days after application (А1.2)- Glufosinate ammonium (81.5)- Metolach lor ime) Table 11

Herbicidal efficacy in a field experiment on corn (active substance(s) Dose") g AR/ha Corn I. Herbicidal efficacy?) (90) against Vgaspigia riapiadipea (A1.2) Г510)8) (9) 82 00 (9) 63 200 (9) 60.0 100 9) 431 dv with 160000 (А1.2)Н(AZ.233) 100-100 (about 92(Е A-86)

tu) yayu 175010 (А 2uk(IV1 8) 10021920 С 83(EA-8О)

Abbreviations to table 11: 1)- application at the C leaf stage 2)- Observation 42 days after application 3)- The second active substance is applied 10 days after the first active substance (A1.2)- Glufosinate ammonium (AZ.2)- Imazetapur (81.6) - Alachlor

Table 12

Herbicidal efficacy in a field experiment on corn

Active ingredient) Dose !) g AR/ha Herbicidal efficiency?) (95) against Rohitsias oiegasea (A1.2) 500 bo 250 35 37 (A1.2)4(83.1) 250-360 v5B(E A-60)

Abbreviations to table 12: 1)- application at the b leaf stage 2)- Observation after 26 days after application (A1.2)- Glufosinate ammonium (83.1)- Bromoxynil 6)

Table 13

Herbicidal efficacy in a field experiment on corn

Active substance) Dose 1) g AR/ha Herbicidal efficiency?) (95) against Zipar aguepvs 230 45 « zo) (A1.2uch(83.6) 230415 o9(E C--85) s-s

Abbreviations to table 13: 1)- Application at the 4-5 leaf stage in 2)- Observation 28 days after application (A1.2)- Glufosinate ammonium (83.6)- Thifensulfuron-methyl

Table 14 - c Herbicidal effectiveness in a field experiment on corn "» Active substance) Dose 7!) g AR/ha Corn TSI | Herbicidal effectiveness?) (95) against n Espiposnpis sgiv-da 111 200 35 -I 8 65 5 40 to (AT 2u(B2 8) goyu 16 VB(EA-TB) - 32 165 (A! 2uk(IV3.4) 2004100 vB(EA-BO)

ЧК» shk Abbreviations to table 14: 1)- application at the C leaf stage 2) Observation 21 days after application (A1.2)- Glufosinate ammonium (82.8)- Flumetsulam (83.4)-. Clopyralid name)

Table 15

Herbicidal efficiency in a field experiment on corn 60

Active substance) Dose 7) g AR/ha Herbicidal efficiency?) (95) against (site aragipe|Radorugyt ezsshepit (A1.2) 500 65 55 250 45 20 125 zo 10 b5

(83.8) bo 85 78 zo 65 bo 45 zo (А1.2)4(83.8) 2504-15 ВБ(ЕС-72) бБ(Е А-5О) 9 125130 в3(ЕС-Т5) TB(EA-TO)

Abbreviations to table 15: 1)- Application at the 3-4 leaf stage 2)- observation 24 days after application (A1.2)- Glufosinate ammonium 70 (83.8)- Tritosulfuron

Table 16

Herbicidal effectiveness in a field experiment on corn 15 Active substance(s) Dose ) g AR/ha Herbicidal effectiveness?) (95) against Zogapyt risoiog (82.53) 100 75 50 40 25 20 (12332) BOO 85 250 50 125 zo (A1. 2)2)(Bv2.5) 7) 5Og250 oB(EA-90) 25250 VO A-70)

Abbreviations to table 16: c 1)- introduction before the stairs o 2)- introduction at stage 4 leaves 18 days after introduction 1) before the stairs

C) - observation 46 days after application before emergence, respectively, 28 days after the second application after emergence (A1.2) - Glufosinate ammonium (82.5) - Isoxaflutol h "

Table 17

Herbicidal efficiency in a field experiment on corn

Active ingredient) Dose 1) g AR/ha Herbicidal effectiveness?) (95) against Espipospis sgiv-oaii ch (A1.2) 500 74 250 45 - 125 25 (81.13) 500 55 250 zo 125 25 « (A1.2) 4(B1.13) 2504125 VB(EL-55) 5BOOni25 100(EA-98) - with 1254500 oZ(EA-80) ;" и Abbreviations to Table 17: 1)- application at the C leaf stage 2)- observation 28 days after application - (A1.2)- Glufosinate ammonium (81.13)- Flutiamide ime) -I Table 18» 50 Herbicidal efficiency in the field experiments on corn

Active substance(s) Dose 7) g AR/ha Herbicidal efficiency" (95) against Espiposnis sgiv-daiii -. (412) BOO 78 250 65 125 45 (81.4) 1500 45 99 750 40

GF) 375 10 (A1.2)4(81.4) 1254750 9З(Е-85) ko 1254-1500 97(Е A-90) 500375 o2(EA-88) 60

Abbreviations to table 18: 1)- Application at the 3-4 leaf stage 2) observation 42 days after application (A1.2)- Ammonium glufosinate (81.4)- Acetochlor b5

Herbicidal efficiency?) (90) against Gatisht atriekhisashcie (Ag) bo 90 400 75 otukva, 70 Abbreviations to table 19: 1)- Applying at stage 1 leaf 2) observation 17 days after application (A2.1)- isopropylammonium-glyphosate (82.3)-. Iodosulfuron-methyl

Herbicidal effectiveness?) (95) against Sopmomiyiv agepviv (Ag) 400 20 200 o (At2unv 00001569 (lt huk) sch vav

GOETHE NIZYN PO ZVI -

Abbreviations to table 20: 1)- Application at the stage of 3-4 leaves « 2) - observation 28 days after application of i- (A2.1)- Isopropylammonium-glyphosate (83.3)-2,4-0 (83.9)- MSRA c (82.2)- Pyridate rch- (81.12)- Dimethenamid

Claims (5)

The formula of the invention "- c 1. A method of weed control in tolerant corn crops by means of joint or separate pre-emergence or post-emergence or pre- and post-emergence application of herbicides to plants, plant parts, plant seeds or to the cultivated surface, which differs in that as herbicides use (A) one or more broad-spectrum herbicides from the group of compounds consisting of - 45 (AT) compounds of formulas (A1) o ; (AT) t Her » i nyu--y -1 / Mr rya no y n. C" MH, where 7 means a residue of the formula -OH or a peptide residue of the formula -"CHNH(СНУСОМНСН(СНЗИСОоОН) or -МНСН(ИНЗСУСОМНСНОСН(СНУ»)И|COOH, and their esters and salts and other derivatives of phosphinothricin, (A2) compounds of the formula (AZ) and their esters and salts, o! ; (Аг) no no Ге) / - ра и з хо цно s 60 n, n. (B) one or more herbicides from the group of compounds consisting of (81) herbicides from the group of cyanazine, alachlor, nicosulfuron, rimsulfuron, flutiamide, sulcotrione, mesotrione and pentoxamide, b (82) herbicides from the group pendimethalin, methosulam, isoxaflutol, metribuzin, cloransulam, flumetsulam, linuron, florasulam and isoxachlortol and (83) herbicides from the group of bromoxynil, 2,4-O, chlorpyralid, thifensulfuron, carfentrazone, tritosulfuron (ar 271272), MSRA, halosulfuron and sulfosulfuron, while components (A) and (B) are taken in a synergistically effective ratio, and the use of a combination herbicides containing a combination of (Ai7) glufosinate and (B) pendimethalin, nicosulfuron, isoxaflutol, flumetsulam, bromoxynil or clopyralid are excluded from harassment. 2. The method according to claim 1, which differs in that ammonium glufosinate is used as the active substance (A). C. The method according to claim 1, which differs in that isopropylammonium glyphosate is used as the active substance (A). 70 4. The method according to one of claims 1-3, which differs in that the process is carried out in the presence of auxiliary substances common in plant protection. 5. Herbicidal agent containing two herbicides and, if necessary, additives and auxiliary substances usual for herbicide agents, which differs in that as herbicides it contains (A) a broad-spectrum herbicide of the formula (A1) /5 Its ! (A) Nn y y y y ke ka ; n, Mn; where 7 means a residue of the formula -OH or a peptide residue of the formula -"ЧНСН(СНУСОМНСН(СНЗИСОоОН or -МНСН(ИНЗСУСОМНСНОСН(СНУ»)|СООН), and (B) a herbicide from the group of compounds consisting of (B1) herbicides of the cyanazine group, alachlor , flutiamide, sulcotrione, mesotrione and pentoxamide, c (82) herbicides of the methosulam, metribuzin, cloransulam, florasulam and isoxachlortol and o (83) herbicides of the carfentrazone, tritosulfuron (I ab 271272), halosulfuron and sulfosulfuron group, while components (A) and (B) taken in a synergistically effective ratio. b. A herbicide containing two herbicides and, if necessary, additives and auxiliary substances common to herbicides, which differs in that it contains, as herbicides - (A) a broad-spectrum herbicide of the formula (Ag) « o ; (Ag) about M | (B) herbicide from the group of compounds consisting of (B1) herbicides of the cyanazine group, alachlor, nicosulfuron, flutiamide, sulcotrione, mesotrione and pentoxamide, (82) herbicides of the pendimethalin group, methosulam, isoxaflutol, metribuzin, cloransulam, - with flumetsulam, linuron, florasulam and isoxachlortol, "from (83) herbicides of the bromoxynil group, 2,4-O, chlorpyralid, thifensulfuron, carfentrazone, tritosulfuron" (ar 271272), MSRA, halosulfuron, diflufenzopyr and sulfosulfuron, while components (A) and (B) are taken in a synergistically effective ratio. - and the Official Bulletin "Industrial Property". Book 1 "Inventions, useful models, topographies of integrated microcircuits", 2005, M 4, 15.04.2005. State Department of Intellectual Property of the Ministry of Education and Science of Ukraine. -I iz 50 - F) ime) 60 b5