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UA66776C2 - Форма похідного тетрагідропіридину у вигляді мікрочастинок - Google Patents

Форма похідного тетрагідропіридину у вигляді мікрочастинок

Info

Publication number
UA66776C2
UA66776C2 UA99063520A UA99063520A UA66776C2 UA 66776 C2 UA66776 C2 UA 66776C2 UA 99063520 A UA99063520 A UA 99063520A UA 99063520 A UA99063520 A UA 99063520A UA 66776 C2 UA66776 C2 UA 66776C2
Authority
UA
Ukraine
Prior art keywords
micro
particle form
tetrahydropyridine derivative
tetrahydropyridine
derivative
Prior art date
Application number
UA99063520A
Other languages
English (en)
Russian (ru)
Inventor
Антуан КАРОН
Жан-П'єр Шамбон
Олівер Монн'є
Original Assignee
Санофі-Сінтелябо
Санофи-Синтелябо
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Санофі-Сінтелябо, Санофи-Синтелябо filed Critical Санофі-Сінтелябо
Publication of UA66776C2 publication Critical patent/UA66776C2/uk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10—Laxatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/06—Free radical scavengers or antioxidants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biochemistry (AREA)
  • Diabetes (AREA)
  • Toxicology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyridine Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Винахід відноситься до форми гідрохлориду 1-[2-(2-нафтил)етил]-4-(3-трифторметилфеніл)-1,2,3,6-тетрагідропіридину у вигляді мікрочастинок, що складається з частинок, принаймні, 55% яких мають діаметр менше 50 мікрометрів, і до фармацевтичних композицій, у яких вона присутня.
UA99063520A 1996-12-23 1997-12-23 Форма похідного тетрагідропіридину у вигляді мікрочастинок UA66776C2 (uk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9615905A FR2757510B1 (fr) 1996-12-23 1996-12-23 Forme microparticulaire d'un derive de tetrahydropyridine
PCT/FR1997/002394 WO1998028272A1 (fr) 1996-12-23 1997-12-23 Forme microparticulaire d'un derive de tetrahydropyridine

Publications (1)

Publication Number Publication Date
UA66776C2 true UA66776C2 (uk) 2004-06-15

Family

ID=9499044

Family Applications (1)

Application Number Title Priority Date Filing Date
UA99063520A UA66776C2 (uk) 1996-12-23 1997-12-23 Форма похідного тетрагідропіридину у вигляді мікрочастинок

Country Status (38)

Country Link
US (4) US20020028247A1 (uk)
EP (1) EP0950051B1 (uk)
JP (2) JP4422214B2 (uk)
KR (1) KR100455797B1 (uk)
CN (1) CN1088698C (uk)
AR (1) AR009673A1 (uk)
AT (1) ATE250032T1 (uk)
AU (1) AU730302B2 (uk)
BR (1) BR9714177A (uk)
CA (1) CA2275593C (uk)
CO (1) CO4920213A1 (uk)
CZ (1) CZ294272B6 (uk)
DE (1) DE69724999T2 (uk)
DK (1) DK0950051T3 (uk)
DZ (1) DZ2386A1 (uk)
EE (1) EE04112B1 (uk)
EG (1) EG24749A (uk)
ES (1) ES2207758T3 (uk)
FR (1) FR2757510B1 (uk)
HK (1) HK1024000A1 (uk)
HU (1) HU224348B1 (uk)
IL (1) IL129937A (uk)
IN (1) IN186977B (uk)
IS (1) IS2064B (uk)
MY (1) MY126298A (uk)
NO (1) NO311569B1 (uk)
NZ (1) NZ336129A (uk)
PL (1) PL190098B1 (uk)
PT (1) PT950051E (uk)
RU (1) RU2193031C2 (uk)
SI (1) SI0950051T1 (uk)
SK (1) SK283917B6 (uk)
TR (1) TR199901362T2 (uk)
TW (1) TW534820B (uk)
UA (1) UA66776C2 (uk)
WO (1) WO1998028272A1 (uk)
YU (1) YU49427B (uk)
ZA (1) ZA9711579B (uk)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7217431B2 (en) * 2001-07-06 2007-05-15 Lifecycle Pharma A/S Controlled agglomeration
BE1015641A4 (fr) * 2003-05-26 2005-07-05 Mariani Jean Paul Micronisation 70.
RU2472490C1 (ru) * 2011-08-05 2013-01-20 Открытое акционерное общество "Биосинтез" Средство для лечения кожных гнойных инфекций, составы и способы получения

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US562883A (en) * 1896-06-30 Thill-coupling
FR2531707A1 (fr) * 1982-08-16 1984-02-17 Midy Spa Trifluoromethylphenyltetrahydropyridines substituees a activite anorexigene, un procede de preparation et compositions pharmaceutiques
US4826689A (en) * 1984-05-21 1989-05-02 University Of Rochester Method for making uniformly sized particles from water-insoluble organic compounds
FR2627696B1 (fr) * 1988-02-26 1991-09-13 Fournier Innovation Synergie Nouvelle forme galenique du fenofibrate
FR2639226B1 (fr) * 1988-11-18 1993-11-05 Sanofi Utilisation de trifluoromethylphenyltetrahydropyridines pour la preparation de medicaments destines a combattre les troubles anxio-depressifs
FR2662355B1 (fr) * 1990-05-22 1994-11-10 Sanofi Sa Utilisation de la 1-[2-(2-naphtyl)ethyl]-4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridine pour la preparation de medicaments destines au traitement de troubles cerebraux et neuronaux.
HU221308B1 (en) * 1992-10-26 2002-09-28 Sanol Arznei Schwarz Gmbh Process for producing microcapsules
US5662883A (en) * 1995-01-10 1997-09-02 Nanosystems L.L.C. Microprecipitation of micro-nanoparticulate pharmaceutical agents
US5560932A (en) * 1995-01-10 1996-10-01 Nano Systems L.L.C. Microprecipitation of nanoparticulate pharmaceutical agents
US6489334B2 (en) * 1996-12-23 2002-12-03 Sanofi-Synthelabo Method for the crystallization of a tetrahydropyridin derivative and resulting crystalline forms
FR2763847B1 (fr) * 1997-05-28 2003-06-06 Sanofi Sa Utilisation de tetrahydropyridines 4-substituees pour fabriquer des medicaments agissant sur le tgf-beta-1
US20020147216A1 (en) * 2000-01-31 2002-10-10 Yuhong Zhou Mucin synthesis inhibitors

Also Published As

Publication number Publication date
KR20000069503A (ko) 2000-11-25
ZA9711579B (en) 1998-06-25
IL129937A0 (en) 2000-02-29
SK283917B6 (sk) 2004-05-04
AU5668598A (en) 1998-07-17
CA2275593C (en) 2005-12-20
NO993077D0 (no) 1999-06-22
US20080255365A1 (en) 2008-10-16
FR2757510A1 (fr) 1998-06-26
DE69724999D1 (de) 2003-10-23
SK82999A3 (en) 1999-12-10
CA2275593A1 (en) 1998-07-02
HK1024000A1 (en) 2000-09-29
BR9714177A (pt) 2000-02-29
CN1241179A (zh) 2000-01-12
IS5077A (is) 1999-06-10
JP2001507013A (ja) 2001-05-29
EP0950051B1 (fr) 2003-09-17
DK0950051T3 (da) 2004-01-26
NZ336129A (en) 2000-11-24
AR009673A1 (es) 2000-04-26
ATE250032T1 (de) 2003-10-15
WO1998028272A1 (fr) 1998-07-02
ES2207758T3 (es) 2004-06-01
EG24749A (en) 2010-07-20
IS2064B (is) 2005-11-15
HUP0001181A3 (en) 2003-03-28
AU730302B2 (en) 2001-03-01
TW534820B (en) 2003-06-01
CZ229199A3 (cs) 1999-09-15
KR100455797B1 (ko) 2004-11-06
IL129937A (en) 2002-09-12
MY126298A (en) 2006-09-29
TR199901362T2 (xx) 1999-09-21
EE9900263A (et) 2000-02-15
HUP0001181A2 (hu) 2000-11-28
JP2009280581A (ja) 2009-12-03
PL190098B1 (pl) 2005-10-31
US20020192292A1 (en) 2002-12-19
CO4920213A1 (es) 2000-05-29
NO311569B1 (no) 2001-12-10
PT950051E (pt) 2004-02-27
CN1088698C (zh) 2002-08-07
FR2757510B1 (fr) 2000-01-07
DZ2386A1 (fr) 2002-12-28
HU224348B1 (hu) 2005-08-29
SI0950051T1 (en) 2004-02-29
US20100021541A1 (en) 2010-01-28
IN186977B (uk) 2001-12-22
US20020028247A1 (en) 2002-03-07
PL334276A1 (en) 2000-02-14
EP0950051A1 (fr) 1999-10-20
CZ294272B6 (cs) 2004-11-10
YU28899A (sh) 2000-03-21
NO993077L (no) 1999-06-22
EE04112B1 (et) 2003-08-15
DE69724999T2 (de) 2004-07-22
YU49427B (sh) 2006-01-16
JP4422214B2 (ja) 2010-02-24
RU2193031C2 (ru) 2002-11-20

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