UA39163C2 - Похідні фосфоліпідів, що мають протипухлинну та/або антипротозойну активність, спосіб їх одержання, фармацевтична композиція на їх основі та спосіб одержання фармацевтичної композиції - Google Patents

Похідні фосфоліпідів, що мають протипухлинну та/або антипротозойну активність, спосіб їх одержання, фармацевтична композиція на їх основі та спосіб одержання фармацевтичної композиції

Info

Publication number: UA39163C2
Authority: UA; Ukraine
Prior art keywords: pharmaceutical composition; preparation; antitumor; phospholipid derivatives; antiprotozoal activity
Prior art date: 1992-10-01

Application number

UA93002238A

Other languages

English (en)

Russian (ru)

Ukrainian (uk)

Inventor

Герхард НЬОСНЕР

Герхард НЕСНЕР

Юрій СТЕКАР

Юрий СТЕКАР

Петер Хільгард

Петер Хильгард

Бернхард Кутшер

Юрген ЕНГЕЛЬ

Юрген Энгель

Original Assignee

Аста Медіка Акціенгезельшафт

Аста Медика Акциенгезельшафт

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-10-01

Filing date

1993-09-30

Publication date

2001-06-15

1993-09-30 Application filed by Аста Медіка Акціенгезельшафт, Аста Медика Акциенгезельшафт filed Critical Аста Медіка Акціенгезельшафт

2001-06-15 Publication of UA39163C2 publication Critical patent/UA39163C2/uk

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/54—Quaternary phosphonium compounds
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/54—Quaternary phosphonium compounds
- C07F9/5407—Acyclic saturated phosphonium compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/66—Arsenic compounds
- C07F9/70—Organo-arsenic compounds
- C07F9/72—Aliphatic compounds

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Molecular Biology (AREA)
Physical Education & Sports Medicine (AREA)
Biochemistry (AREA)
Oncology (AREA)
Rheumatology (AREA)
Diabetes (AREA)
Orthopedic Medicine & Surgery (AREA)
Hematology (AREA)
Communicable Diseases (AREA)
Virology (AREA)
Tropical Medicine & Parasitology (AREA)
Immunology (AREA)
Epidemiology (AREA)
Obesity (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Fats And Perfumes (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Cephalosporin Compounds (AREA)
Inorganic Compounds Of Heavy Metals (AREA)
Compounds Of Unknown Constitution (AREA)

UA93002238A 1992-10-01 1993-09-30 Похідні фосфоліпідів, що мають протипухлинну та/або антипротозойну активність, спосіб їх одержання, фармацевтична композиція на їх основі та спосіб одержання фармацевтичної композиції UA39163C2 (uk)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE4233044A DE4233044A1 (de)	1992-10-01	1992-10-01	Phospholipidderivate, die höhere Elemente der V. Hauptgruppe enthalten

Publications (1)

Publication Number	Publication Date
UA39163C2 true UA39163C2 (uk)	2001-06-15

Family

ID=6469408

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
UA93002238A UA39163C2 (uk)	1992-10-01	1993-09-30	Похідні фосфоліпідів, що мають протипухлинну та/або антипротозойну активність, спосіб їх одержання, фармацевтична композиція на їх основі та спосіб одержання фармацевтичної композиції

Country Status (23)

Country	Link
US (2)	US5449798A (hu)
EP (1)	EP0594999B1 (hu)
JP (1)	JP3688304B2 (hu)
KR (1)	KR100331367B1 (hu)
CN (1)	CN1055697C (hu)
AT (1)	ATE174030T1 (hu)
AU (1)	AU661795B2 (hu)
BR (1)	BR9303990A (hu)
CA (1)	CA2107439C (hu)
DE (2)	DE4233044A1 (hu)
DK (1)	DK0594999T3 (hu)
EG (1)	EG20258A (hu)
ES (1)	ES2125935T3 (hu)
FI (1)	FI111261B (hu)
GR (1)	GR3029423T3 (hu)
HU (1)	HU220593B1 (hu)
IL (1)	IL107141A (hu)
MX (1)	MX9306076A (hu)
NO (1)	NO305911B1 (hu)
PH (1)	PH29951A (hu)
RU (1)	RU2126413C1 (hu)
UA (1)	UA39163C2 (hu)
ZA (1)	ZA937282B (hu)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AUPP026997A0 (en)	1997-11-07	1997-12-04	Resmed Limited	Administration of cpap treatment pressure in presence of apnea
WO2004062594A2 (en) *	2003-01-09	2004-07-29	Zeneus Pharma Limited	Antineoplastic ether lipid compounds with modifications at the sn-3 carbon
AU2006328479B2 (en)	2005-12-19	2012-03-08	Aeterna Zentaris Gmbh	Alkyl phospholipid derivatives with reduced cytotoxicity and uses thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4177216A (en) *	1974-06-21	1979-12-04	The Dow Chemical Company	Novel tributyl (2,5-dihydroxyphenyl)phosphonium hydroxide inner salts
US4177716A (en) *	1978-02-21	1979-12-11	Gerald J. Bowe	Automatic energy saver and fire damper for exhaust systems
JPS5984824A (ja) *	1982-11-08	1984-05-16	Takeda Chem Ind Ltd	抗腫瘍剤
EP0916343A1 (de) *	1989-09-27	1999-05-19	ASTA Medica Aktiengesellschaft	Verwendung von Alkylphosphorsäure-Verbindungen zur Bekämpfung von Psoriasis-Erkrankungen
DE3942933A1 (de) *	1989-12-23	1991-06-27	Boehringer Mannheim Gmbh	Verwendung von alkylphospholipiden als antivirale arzneimittel und neue phospholipid-derivate
DE4111105A1 (de) *	1991-04-05	1992-10-08	Max Planck Gesellschaft	Neue erucyl-, brassidyl- und nervonylderivate

1992
- 1992-10-01 DE DE4233044A patent/DE4233044A1/de not_active Withdrawn
1993
- 1993-06-25 EG EG92893A patent/EG20258A/xx active
- 1993-09-13 DK DK93114671T patent/DK0594999T3/da active
- 1993-09-13 AT AT93114671T patent/ATE174030T1/de not_active IP Right Cessation
- 1993-09-13 EP EP93114671A patent/EP0594999B1/de not_active Expired - Lifetime
- 1993-09-13 DE DE59309182T patent/DE59309182D1/de not_active Expired - Fee Related
- 1993-09-13 ES ES93114671T patent/ES2125935T3/es not_active Expired - Lifetime
- 1993-09-22 US US08/124,492 patent/US5449798A/en not_active Expired - Lifetime
- 1993-09-28 IL IL107141A patent/IL107141A/en not_active IP Right Cessation
- 1993-09-28 CN CN93118218A patent/CN1055697C/zh not_active Expired - Fee Related
- 1993-09-28 KR KR1019930020113A patent/KR100331367B1/ko not_active Expired - Fee Related
- 1993-09-30 UA UA93002238A patent/UA39163C2/uk unknown
- 1993-09-30 NO NO933505A patent/NO305911B1/no unknown
- 1993-09-30 MX MX9306076A patent/MX9306076A/es unknown
- 1993-09-30 BR BR9303990A patent/BR9303990A/pt not_active Application Discontinuation
- 1993-09-30 ZA ZA937282A patent/ZA937282B/xx unknown
- 1993-09-30 AU AU48747/93A patent/AU661795B2/en not_active Ceased
- 1993-09-30 RU RU93054776A patent/RU2126413C1/ru not_active IP Right Cessation
- 1993-09-30 PH PH46986A patent/PH29951A/en unknown
- 1993-09-30 FI FI934297A patent/FI111261B/fi active
- 1993-09-30 HU HU9302772A patent/HU220593B1/hu not_active IP Right Cessation
- 1993-09-30 CA CA002107439A patent/CA2107439C/en not_active Expired - Fee Related
- 1993-10-01 JP JP24683293A patent/JP3688304B2/ja not_active Expired - Fee Related
1995
- 1995-04-14 US US08/421,920 patent/US5637577A/en not_active Expired - Fee Related
1999
- 1999-02-17 GR GR990400506T patent/GR3029423T3/el unknown

Also Published As

Publication number	Publication date
AU661795B2 (en)	1995-08-03
DE4233044A1 (de)	1994-04-07
US5449798A (en)	1995-09-12
CA2107439A1 (en)	1994-04-02
US5637577A (en)	1997-06-10
DK0594999T3 (da)	1999-08-16
JPH06199876A (ja)	1994-07-19
FI934297A0 (fi)	1993-09-30
FI111261B (fi)	2003-06-30
BR9303990A (pt)	1994-06-14
CA2107439C (en)	2006-08-15
HU220593B1 (hu)	2002-03-28
IL107141A0 (en)	1993-12-28
EP0594999B1 (de)	1998-12-02
PH29951A (en)	1996-09-16
ZA937282B (en)	1994-04-25
EP0594999A1 (de)	1994-05-04
JP3688304B2 (ja)	2005-08-24
MX9306076A (es)	1994-05-31
KR100331367B1 (ko)	2002-11-13
RU2126413C1 (ru)	1999-02-20
HUT65681A (en)	1994-07-28
AU4874793A (en)	1994-04-14
NO933505L (no)	1994-04-05
NO305911B1 (no)	1999-08-16
GR3029423T3 (en)	1999-05-28
ES2125935T3 (es)	1999-03-16
EG20258A (en)	1998-05-31
HU9302772D0 (en)	1993-12-28
DE59309182D1 (de)	1999-01-14
FI934297L (fi)	1994-04-02
NO933505D0 (no)	1993-09-30
CN1088583A (zh)	1994-06-29
KR940009201A (ko)	1994-05-20
CN1055697C (zh)	2000-08-23
IL107141A (en)	1998-01-04
ATE174030T1 (de)	1998-12-15

Publication	Publication Date	Title
UA32546C2 (uk)	2001-02-15	1,2-заміщені 1н-імідазо[4,5-с]хінолін-4-аміни, проміжні сполуки для їх синтезу, антивірусна фармацевтична композиція, спосіб лікування інфікованих ссавців, спосіб індукування біосинтезу інтерферону у ссавців, спосіб уповільнення росту бластом
ES2130452T3 (es)	1999-07-01	Derivados de ciclobutano utilizados como inhibidores de la escualeno-sintetasa y de la farnesiltransferasa proteica.
MX9601360A (es)	1997-04-30	Mezcla estabilizante sinergistica.
AU591860B2 (en)	1989-12-14	Pyrolidineamide derivative having anti-prolyl endopeptidase
ES8706717A1 (es)	1987-07-01	Metodo de preparar esteroides
GR850472B (hu)	1985-05-31
FR2515179B1 (hu)	1985-01-18
MY110747A (en)	1999-02-27	Quinolone-and naphthyridonecarboxylic acid derivatives
GR3001441T3 (en)	1992-09-25	Pyrrolidinylamide ester derivative having anti-prolyl endopeptidase activity, its synthesis and use and a pharmaceutical composition containing it
MY105538A (en)	1994-10-31	Derivatives of thieno-triazolo-diazepine, a preparation process of the same and therapeutic compositions containing them.
AP9300561A0 (en)	1995-02-26	Antibiotic compounds.
GR3031602T3 (en)	2000-01-31	Novel 2-substituted indane-2-mercaptoacetylamide tricyclic derivatives useful as inhibitors of enkephalinase.
MX9801190A (es)	1998-04-30	Inhibidores de prolil endopeptidasa.
UA66866C2 (uk)	2004-06-15	Синтез морфолінових похідних
UA39163C2 (uk)	2001-06-15	Похідні фосфоліпідів, що мають протипухлинну та/або антипротозойну активність, спосіб їх одержання, фармацевтична композиція на їх основі та спосіб одержання фармацевтичної композиції
MX9603348A (es)	1997-12-31	Derivados de disulfuro de amida indano-2-mercaptoacetilica novedosos utiles como inhibidores de encefalinasa.
NZ212658A (en)	1988-02-29	Phenylnaphthyridine derivatives and pharmaceutical compositions
BG99313A (en)	1995-09-29	117-alkylketonesteroids as 5- -reductase inhibitors
TW371661B (en)	1999-10-11	Novel intermediates and their use to prepare N,N'-bridged bisindolylmaleimides
GB9324931D0 (en)	1994-01-26	Glutaramide derivatives
IE872578L (en)	1988-03-26	Antigestagen compositions
EP0161492A3 (en)	1986-05-07	Estrogen synthesis inhibitors
ES8602676A1 (es)	1985-10-01	Un procedimiento para la preparacion de nuevos derivados de pirrolo-(2,1-a)isoquilonina.
AU547341B2 (en)	1985-10-17	Antibiotic compounds
NZ214449A (en)	1989-01-06	13-alpha-alkylgonanes and pharmaceutical compositions