TW238300B - - Google Patents

Info

Publication number: TW238300B
Authority: TW; Taiwan
Prior art keywords: alkyl; hydrogen; butoxy; chem; tert
Prior art date: 1991-10-04

Application number

TW081107817A

Other languages

English (en)

Original Assignee

Nissan Chemical Ind Ltd

Kyowa Kk

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-10-04

Filing date

1992-10-01

Publication date

1995-01-11

1992-10-01 Application filed by Nissan Chemical Ind Ltd, Kyowa Kk filed Critical Nissan Chemical Ind Ltd

1995-01-11 Application granted granted Critical

1995-01-11 Publication of TW238300B publication Critical patent/TW238300B/zh

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pyridine Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Quinoline Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

TW081107817A 1991-10-04 1992-10-01 TW238300B (zh)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP03257870A JP3130342B2 (ja)	1991-10-04	1991-10-04	動脈硬化性血管内膜肥厚抑制薬

Publications (1)

Publication Number	Publication Date
TW238300B true TW238300B (zh)	1995-01-11

Family

ID=17312323

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
TW081107817A TW238300B (zh)	1991-10-04	1992-10-01

Country Status (18)

Country	Link
US (1)	US6162798A (zh)
EP (1)	EP0535548B1 (zh)
JP (1)	JP3130342B2 (zh)
KR (1)	KR100264543B1 (zh)
AT (1)	ATE209035T1 (zh)
AU (1)	AU652669B2 (zh)
CA (1)	CA2079706C (zh)
CZ (1)	CZ281786B6 (zh)
DE (1)	DE69232217T2 (zh)
DK (1)	DK0535548T3 (zh)
HU (1)	HU214624B (zh)
MX (1)	MX9205659A (zh)
NO (1)	NO302452B1 (zh)
NZ (1)	NZ244555A (zh)
RU (1)	RU2114620C1 (zh)
SK (1)	SK279277B6 (zh)
TW (1)	TW238300B (zh)
UA (1)	UA39095C2 (zh)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1995011898A1 (en) *	1992-05-12	1995-05-04	Nissan Chemical Industries Ltd.	Condensed pyridine type mevalonolactone intermediate and process for its production
ATE243034T1 (de) *	1996-01-17	2003-07-15	Taiho Pharmaceutical Co Ltd	Intimale verdickungsinhibitoren
US6335449B1 (en) *	1998-07-23	2002-01-01	Nissan Chemical Industries, Ltd.	Process for the preparation of quinoline derivative and intermediate therefor
AU754977B2 (en)	1999-01-14	2002-11-28	Nissan Chemical Industries Ltd.	Process for producing quinolinecarbaldehyde
AU2001227100A1 (en) *	2000-01-24	2001-07-31	Nissan Chemical Industries Ltd.	Process for the preparation of quinolylpropenal
JP4496585B2 (ja) *	2000-01-24	2010-07-07	日産化学工業株式会社	キノリルプロペナールの製造方法
JP4496586B2 (ja) *	2000-01-24	2010-07-07	日産化学工業株式会社	キノリルアクリロニトリルの製造法及びその中間体
JP4496584B2 (ja) *	2000-01-24	2010-07-07	日産化学工業株式会社	キノリルプロペナールの製造法
AU2001232342A1 (en)	2000-02-21	2001-08-27	Kuraray Co. Ltd.	Processes for preparing quinoline derivatives and intermediates thereof
JP4867071B2 (ja) *	2000-02-21	2012-02-01	日産化学工業株式会社	キノリン誘導体の製造方法
WO2001098301A1 (fr) *	2000-06-20	2001-12-27	Japan Tobacco Inc.	Composes de pyrazolopyridine et utilisation de ces derniers en tant que medicaments
WO2003075741A2 (en) *	2002-03-04	2003-09-18	Medimmune, Inc.	METHODS OF PREVENTING OR TREATING DISORDERS BY ADMINISTERING AN INTEGRIN αvβ3 ANTAGONIST IN COMBINATION WITH AN HMG-CoA REDUCTASE INHIBITOR OR A BISPHOSPHONATE
CN100378077C (zh) *	2002-11-06	2008-04-02	日产化学工业株式会社	喹啉甲醛类的制造方法
WO2004041787A1 (ja) *	2002-11-06	2004-05-21	Nissan Chemical Industries, Ltd.	キノリンカルバルデヒド類の製造方法
US7420059B2 (en) *	2003-11-20	2008-09-02	Bristol-Myers Squibb Company	HMG-CoA reductase inhibitors and method
AR047329A1 (es)	2003-12-12	2006-01-18	Wyeth Corp	Derivados de quinolinas para el tratamiento de enfermedades cardiovasculares. composiciones farmaceuticas
ES2319797T3 (es) *	2004-07-05	2009-05-12	Astellas Pharma Inc.	Derivados de pirazolopiridina.
CN100445267C (zh) *	2005-10-21	2008-12-24	上海医药工业研究院	4-(4-氟-苯基)-3-羟甲基-2-环丙基-喹啉的制备方法
GEP201706620B (en)	2012-06-29	2017-02-10	Pfizer	NOVEL 4-(SUBSTITUTED-AMINO)-7H-PYRROLO[2,3-d]PYRIMIDINES AS LRRK2 INHIBITORS
CN103204807B (zh) *	2013-04-08	2015-12-23	黄河三角洲京博化工研究院有限公司	一种2-环丙基-4-（4-氟-苯基）-3-喹啉甲醛的合成方法
AU2014362144B2 (en) *	2013-12-13	2018-05-10	Daiichi Sankyo Company,Limited	5-hydroxy-4-(trifluoromethyl)pyrazolopyridine derivative
WO2015092592A1 (en)	2013-12-17	2015-06-25	Pfizer Inc.	Novel 3,4-disubstituted-1h-pyrrolo[2,3-b]pyridines and 4,5-disubstituted-7h-pyrrolo[2,3-c]pyridazines as lrrk2 inhibitors
CN104031034B (zh) *	2014-07-01	2017-01-04	上海信谊百路达药业有限公司	一种匹伐他汀钙原料药中间体的制备方法
EP3350178B1 (en)	2015-09-14	2021-10-20	Pfizer Inc.	Novel imidazo [4,5-c]quinoline and imidazo [4,5-c][1,5]naphthyridine derivatives as lrrk2 inhibitors

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA1336714C (en) *	1987-08-20	1995-08-15	Yoshihiro Fujikawa	Quinoline type mevalonolactone inhibitors of cholesterol biosynthesis
JP2569746B2 (ja) *	1987-08-20	1997-01-08	日産化学工業株式会社	キノリン系メバロノラクトン類
US4761419A (en) *	1987-12-07	1988-08-02	Warner-Lambert Company	6-(((substituted)quinolinyl)ethyl)-and ethenyl)tetrahydro-4-hydroxypyran-2-one inhibitors of cholesterol biosynthesis
US4822799A (en) *	1988-01-27	1989-04-18	Sandoz Pharm. Corp.	Pyrazolopyridine analogs of mevalonolactone and derivatives thereof useful for inhibiting cholesterol biosynthesis in mammals
US5024999A (en) *	1988-04-26	1991-06-18	Nissan Chemical Industries Ltd.	Pyrazolopyridine type mevalonolactones useful as pharmaeuticals
JP2890448B2 (ja) *	1988-04-26	1999-05-17	日産化学工業株式会社	ピラゾロピリジン系メバロノラクトン類
US5026698A (en) *	1988-11-02	1991-06-25	Nissan Chemical Industries, Ltd.	Thienopyridine type mevalonolactones

1991
- 1991-10-04 JP JP03257870A patent/JP3130342B2/ja not_active Expired - Fee Related
1992
- 1992-09-24 EP EP92116417A patent/EP0535548B1/en not_active Expired - Lifetime
- 1992-09-24 DE DE69232217T patent/DE69232217T2/de not_active Expired - Lifetime
- 1992-09-24 DK DK92116417T patent/DK0535548T3/da active
- 1992-09-24 AT AT92116417T patent/ATE209035T1/de not_active IP Right Cessation
- 1992-09-28 AU AU26012/92A patent/AU652669B2/en not_active Ceased
- 1992-09-30 US US07/953,716 patent/US6162798A/en not_active Expired - Fee Related
- 1992-09-30 NZ NZ244555A patent/NZ244555A/en not_active IP Right Cessation
- 1992-10-01 TW TW081107817A patent/TW238300B/zh not_active IP Right Cessation
- 1992-10-02 RU SU5052949A patent/RU2114620C1/ru active
- 1992-10-02 CA CA002079706A patent/CA2079706C/en not_active Expired - Fee Related
- 1992-10-02 MX MX9205659A patent/MX9205659A/es unknown
- 1992-10-02 KR KR1019920018157A patent/KR100264543B1/ko not_active IP Right Cessation
- 1992-10-02 HU HU9203138A patent/HU214624B/hu not_active IP Right Cessation
- 1992-10-02 NO NO923858A patent/NO302452B1/no not_active IP Right Cessation
- 1992-10-02 CZ CS923027A patent/CZ281786B6/cs not_active IP Right Cessation
- 1992-10-02 SK SK3027-92A patent/SK279277B6/sk not_active IP Right Cessation
1993
- 1993-04-22 UA UA93002706A patent/UA39095C2/uk unknown

Also Published As

Publication number	Publication date
JP3130342B2 (ja)	2001-01-31
KR100264543B1 (ko)	2001-10-24
CZ281786B6 (cs)	1997-01-15
CA2079706C (en)	2004-03-30
NO923858L (no)	1993-04-05
DE69232217T2 (de)	2002-05-23
CA2079706A1 (en)	1993-04-15
DK0535548T3 (da)	2002-05-13
CZ302792A3 (en)	1993-10-13
EP0535548B1 (en)	2001-11-21
HU214624B (hu)	1998-04-28
KR930007449A (ko)	1993-05-20
NZ244555A (en)	2000-06-23
NO302452B1 (no)	1998-03-09
DE69232217D1 (de)	2002-01-03
MX9205659A (es)	1993-04-01
NO923858D0 (no)	1992-10-02
SK279277B6 (sk)	1998-09-09
RU2114620C1 (ru)	1998-07-10
AU2601292A (en)	1993-04-08
EP0535548A1 (en)	1993-04-07
AU652669B2 (en)	1994-09-01
HUT62794A (en)	1993-06-28
ATE209035T1 (de)	2001-12-15
SK302792A3 (en)	1995-11-08
US6162798A (en)	2000-12-19
UA39095C2 (uk)	2001-06-15
JPH06329540A (ja)	1994-11-29

Publication	Publication Date	Title
TW238300B (zh)	1995-01-11
ATE114645T1 (de)	1994-12-15	Mevalonolaktone vom chinolin-typ.
IL104614A (en)	1997-04-15	4-benzoylisoxazole derivatives and herbicidal compositions comprising them
SI2270010T1 (sl)	2012-05-31	hidroksi H pirolo c benzodiazepin onski derivati kot ključni intermediati za pripravo C substituiranih pirolobenzodiazepinov
MY110447A (en)	1998-05-30	New herbicides
MY153023A (en)	2014-12-31	Tropane derivatives useful in therapy
BR8305546A (pt)	1984-05-15	Processo para a preparacao de derivados substituidos de 1-hidroxietil-triazolilo, composicoes de protecao as plantas e fungicidas e processos para o combate a fungos, para a protecao de plantas e para a preparacao de composicoes
MX9710375A (es)	1998-07-31	Cetales y espirociclicos herbicidas.
FI943508A0 (fi)	1994-07-26	Pyridiinikarboksimidamidiyhdisteet ja niiden käyttö
ES8304579A1 (es)	1983-03-01	Un procedimiento para la preparacion de orto (sulfonil) oxibenceno-sulfonamidas.
DE69018335D1 (de)	1995-05-11	Imidazochinolonderivate.
GB9015485D0 (en)	1990-08-29	Heterocyclic derivatives
GB9324871D0 (en)	1994-01-19	Novel compounds
FI853907L (fi)	1986-04-10	Mellanprodukter foer framstaellning av 16-fenoxi- och 16-substituerade fenoxi-prostatriensyraderivat.
JPS5350195A (en)	1978-05-08	Beta-lactam compounds
HU9203236D0 (en)	1992-12-28	Pharmaceutical preparatives containing triazole derivatives being applicable rectally
BR8704391A (pt)	1988-04-19	Composto,processo para sua preparacao,composicao herbicida e processo para combater o crescimento de planta indesejada
MX9303490A (es)	1994-08-31	Proceso para preaparar (1'r.3s 4r) 4-aciltio-azetidinonas.
MX9601953A (es)	1997-08-30	Nuevo compesto derivados de 5h-tiazolo [3,2-a] pirimidin-5-ona.
IL74633A (en)	1988-11-15	Synergistic herbicidal compositions comprising trimethylsulphonium salt of n-phosphonomethyl-glycine and 1-m-trifluoromethyl-phenyl-3-chloro-4-chloromethyl-2-pyrrolidone

Legal Events

Date	Code	Title	Description
2012-11-11	MK4A	Expiration of patent term of an invention patent