TW202116946A - Adhesive tape or sheet for medical use - Google Patents

Abstract

The present invention relates to an adhesive tape or sheet for medical use, said adhesive tape or sheet having an adhesive layer on at least one surface of a fabric, wherein: the adhesive layer contains an organic liquid component and an acrylic adhesive that has a carboxyl group in each molecule, with at least some carboxyl groups being neutralized; and the bulk density of the fabric is from 0.15 to 0.40 g/cm3.

Description

Adhesive tape or sheet for medical use

The present invention relates to a medical adhesive tape or sheet for sticking to the skin.

Medical adhesive tapes or sheets are used to protect the skin surface by being attached to the skin surface, or to fix medical tubes, catheters, and medical equipment on the skin surface.

For such medical adhesive tapes or sheets, fabric is used as a base material for reasons such as economical low cost (refer to Patent Document 1). Medical adhesive tapes or sheets that use fabric as a base material are usually produced by directly applying an adhesive solution mixed with a solvent such as an organic solvent on the fabric as the base material.

However, in the above-mentioned manufacturing method, the adhesive solution may ooze from the back surface of the fabric. In addition, after the fabric coated with the adhesive solution is formed into a long roll-shaped adhesive tape (hereinafter referred to as a log roll) wound on the core, if it is performed to stabilize the characteristics Heating aging, there is a situation in which winding gaps are generated in the semi-finished rolls after heating aging. Therefore, there is a risk of causing appearance defects such as deformation of a part of the semi-finished roll (concave and convex on the surface). [Prior Technical Literature] [Patent Literature]

Patent Document 1: Japanese Patent Laid-Open No. 2010-082102

[The problem to be solved by the invention]

The object of the present invention is to provide a medical adhesive tape or sheet, which can prevent the adhesive even if the adhesive solution is directly applied to the fabric in the manufacturing method of the medical adhesive tape or sheet using cloth as the base material The solution oozes from the back of the fabric, and even if it is heated and aged after being formed into a semi-finished roll, there will be no winding gaps in the semi-finished roll and the appearance is good. [Technical means to solve the problem]

The inventors of the present invention have made repeated studies in order to achieve the above-mentioned object. As a result, they have found that the adhesive layer has a carboxyl group and a carboxyl group in the molecule by targeting a medical adhesive tape or sheet having an adhesive layer on at least one side of the fabric. At least a part of the neutralized acrylic adhesive and the organic liquid component are used, and the above-mentioned fabric is made into a fabric having a specific bulk density, which can solve the above-mentioned problems, and the present invention has been completed.

The present invention based on the above findings is as follows. (1) An adhesive tape or sheet for medical use, which has an adhesive layer on at least one side of a fabric, and the adhesive layer contains an acrylic adhesive having a carboxyl group in the molecule and at least a part of the carboxyl group is neutralized, and Organic liquid ingredients, the bulk density of the fabric is 0.15～0.40 g/cm ³ . (2) The medical adhesive tape or sheet as described in (1) above, wherein the bulk density of the fabric is 0.30 to 0.40 g/cm ³ . (3) The medical adhesive tape or sheet as described in (1) or (2) above, wherein the content of the organic liquid component in the adhesive layer is 20 to 120 parts by mass relative to 100 parts by mass of the acrylic adhesive. (4) The medical adhesive tape or sheet as described in any one of (1) to (3) above, wherein the organic liquid component is glycerin fatty acid ester or sorbitan fatty acid ester. (5) The medical adhesive tape or sheet as described in any one of (1) to (4) above, wherein 1/5 to 1/1 of the carboxyl groups in the acrylic adhesive are neutralized. (6) The medical adhesive tape or sheet as described in any one of (1) to (5) above, wherein the content of the monomer having a carboxyl group in the molecule is relative to 100 masses of all monomers constituting the acrylic adhesive Parts are 1-20 parts by mass. (7) The medical adhesive tape or sheet as described in any one of (1) to (6) above, wherein the air permeability of the fabric is 0.6 seconds or less. (8) A medical adhesive tape or sheet wound body wound with the medical adhesive tape or sheet as described in any one of (1) to (7) above. [Effects of Invention]

According to the medical adhesive tape or sheet of the embodiment of the present invention, even if the adhesive solution is directly applied to the fabric, the adhesive solution can be prevented from oozing out from the back surface of the fabric.

In addition, it is possible to provide good adhesiveness (grip properties) between the fabric and the adhesive layer, and therefore it is possible to prevent the occurrence of problems such as paste residue when peeling off after the medical adhesive tape or sheet is attached to the skin.

Furthermore, even if the heat aging to stabilize the characteristics is performed after forming into a semi-finished roll, there is no winding gap in the semi-finished roll, and it is possible to suppress the appearance of a part of the semi-finished roll such as deformation (concave and convex on the surface). bad.

Hereinafter, the preferred embodiments of the present invention will be described, but the present invention is not limited to these specific embodiments.

One embodiment of the present invention is a medical adhesive tape or sheet, which is characterized in that it is a cloth having an adhesive layer on at least one side, and the adhesive layer contains a carboxyl group in the molecule and at least a part of the carboxyl group is centered With the acrylic adhesive and organic liquid components, the bulk density of the fabric is 0.15～0.40 g/cm ³ .

The cloth in this embodiment refers to cloth-like objects such as woven cloth, non-woven cloth, and woven cloth. The non-woven fabric in the above-mentioned fabric is fabricated by bonding or winding fibers by thermal, mechanical, or chemical action. Therefore, there is little occurrence of skipping yarn and the like, and it is economically inexpensive, so it is suitable for use.

In addition, the above-mentioned fabric has a porous structure. Therefore, if the adhesive solution is directly applied to the fabric, the adhesive solution easily penetrates into the fabric having a porous structure. Therefore, the obtained medical adhesive tape or sheet can impart good adhesiveness (holding property) between the fabric and the adhesive layer.

As the material of the cloth, for example, natural fibers such as cotton (cotton yarn), silk, hemp, pulp, wool, polyester (such as polyethylene terephthalate, etc.), polyolefin (such as polyethylene, polypropylene, etc.) can be used. ), polyamide (e.g. nylon, etc.), acrylic resin, synthetic fibers such as polyurethane, semi-synthetic fibers such as acetate fibers, regenerated fibers such as rayon fibers, cupra fibers, etc.

One material selected from the above-mentioned materials may be used alone, or two or more materials may be mixed and used. In addition, in a fabric including a plurality of fiber assemblies, all the fibers in the fabric may be of the same material, or fibers of different materials may be mixed to form the fabric.

The bulk density of the fabric in this embodiment is characterized by being 0.15 to 0.40 g/cm ³ . The upper limit of the bulk density of the fabric is preferably 0.39 g/cm ³ , more preferably 0.38 g/cm ³ . In addition, the lower limit of the bulk density of the fabric is preferably 0.20 g/cm ³ , more preferably 0.30 g/cm ³ .

In addition, the thickness of the fabric in this embodiment is preferably 30 to 300 μm. The upper limit of the thickness of the fabric is more preferably 250 μm, and still more preferably 200 μm. The lower limit of the thickness of the fabric is more preferably 40 μm, and still more preferably 50 μm.

The upper limit of the basis weight of the fabric is preferably 100 g/m ² , more preferably 80 g/m ² . The lower limit of the basis weight of the fabric is preferably 10 g/m ² , more preferably 20 g/m ² . The so-called basis weight of cloth means the weight ^{per 1 m 2.}

In addition, the bulk density (g/cm ³ ) of the fabric in this embodiment is calculated by dividing the basis weight (g/m ² ) of the fabric by the thickness (μm). By setting the bulk density of the fabric to 0.15～0.40 g/cm ³ , in the step of making medical adhesive tapes or sheets, even after forming into semi-finished rolls, heat aging is performed to stabilize the characteristics. In the semi-finished roll, there is no winding gap, etc., and it is possible to suppress a part of the semi-finished roll from deforming (producing irregularities on the surface) and other appearance defects.

In addition, the air permeability of the fabric is preferably 0.6 seconds or less. If the air permeability of the fabric is 0.6 seconds or less, even if the semi-finished roll is heated and aged, it is possible to reduce the occurrence of winding gaps in the semi-finished roll, resulting in poor appearance such as deformation of a part of the semi-finished roll (so-called uneven thickness).

Furthermore, the air permeability in this embodiment refers to the 8 pieces of fabric layered and measured by the Gurley air permeability meter to measure the time required to pass 100 cc of air ^{per area of 642.10 mm 2 (diameter 28.6 mmϕ) (test} Conditions: temperature 23±2℃, humidity 65±5%RH).

The fabric in this embodiment usually has a sheet-like shape with two main surfaces, and has an adhesive layer on at least one of the two main surfaces. An adhesive layer can be provided on one side of the fabric, or an adhesive layer can be provided on both sides of the fabric.

The adhesive layer in this embodiment is characterized by containing an acrylic adhesive having a carboxyl group in the molecule and at least a part of the carboxyl group is neutralized, and an organic liquid component.

The acrylic adhesive having a carboxyl group in the molecule contains a monomer having a carboxyl group in the molecule as an essential component. Examples of the monomer having a carboxyl group in the molecule include (meth)acrylic acid, itaconic acid, crotonic acid, fumaric acid, maleic acid (anhydride), and the like. Among them, (meth)acrylic acid can be preferably used in terms of copolymerization and handling properties.

As a monomer copolymerizable with a monomer having a carboxyl group in the molecule, an alkyl (meth)acrylate monomer can be used. The (meth)acrylic acid alkyl ester single system is a component that imparts the adhesive layer to the skin. It is effective that the carbon number of the alkyl group is preferably 2 or more, more preferably 4-18, and more preferably 6-16 alkyl (meth)acrylates.

As the alkyl (meth)acrylate, specifically, the alkyl group is ethyl, propyl, butyl, pentyl, hexyl, heptyl, octyl, 2-ethylhexyl, nonyl, and isononyl. Base, decyl, undecyl, dodecyl, tridecyl, etc. Among them, 2-ethylhexyl and isononyl can be preferably used. Furthermore, these can be used alone or in combination of two or more, and the alkyl ester chain can be either linear or branched.

Compared with rubber-based adhesives, acrylic adhesives contain less impurities and are less irritating to the skin. Furthermore, they have the advantage that the adhesive strength is not easily reduced even if they are attached for a long time.

The content of the monomer having a carboxyl group in the molecule is preferably 20 parts by mass, more preferably 10 parts by mass relative to 100 parts by mass of all monomers constituting the acrylic adhesive.

In addition, the lower limit of the content of the monomer having a carboxyl group in the molecule is preferably 1 part by mass, and more preferably 3 parts by mass with respect to 100 parts by mass of all monomers constituting the acrylic adhesive. If the content of the monomer having a carboxyl group in the molecule is within the above range, excellent cohesive force can be imparted to the adhesive layer, the paste residue phenomenon can be suppressed, etc., and skin irritation can also be suppressed.

Regarding the acrylic adhesive in this embodiment, in addition to the above-mentioned monomers, other monomers may be copolymerized as long as the adhesive properties are not impaired. Examples of such monomers include: styrene sulfonic acid, allyl sulfonic acid, sulfopropyl (meth)acrylate, (meth)acryloyloxynaphthalene sulfonic acid, acrylamide methyl propanesulfonate Acid and other monomers containing sulfonyl groups, hydroxyethyl (meth)acrylate, hydroxypropyl (meth)acrylate and other hydroxyl-containing monomers, (meth)acrylamide, dimethyl(meth)propylene Amido, N-butyl (meth)acrylamide, N-methylol (meth)acrylamide, N-methylolpropane (meth)acrylamide and other monomers containing amide groups, Amino ethyl (meth)acrylate, dimethylaminoethyl (meth)acrylate, tertiary butylaminoethyl (meth)acrylate and other monomers containing amino groups, methoxy (meth)acrylate Ethyl ethyl, ethoxy ethyl (meth)acrylate and other alkoxy alkyl-containing monomers, methoxy glycol (meth) acrylate, methoxy diethylene glycol (meth) acrylic acid Ester, methoxypolyethylene glycol (meth)acrylate, methoxypolypropylene glycol (meth)acrylate and other alkoxy-containing monomers, (meth)acrylonitrile, vinyl acetate, vinyl propionate Vinyl monomers such as esters and vinylpyrrolidone. These can be used alone or in combination of two or more as needed.

At least a part of the carboxyl group of the acrylic adhesive in this embodiment is neutralized. For example, in an acrylic adhesive having a carboxyl group in the molecule, 1/5 to 1/1 of the carboxyl group is preferably neutralized. Here, the term “1/5 to 1/1 of the carboxyl group is neutralized” means that the ratio of the number of moles of the neutralized carboxyl group to the number of moles of all carboxyl groups in the molecule is 1/5 to 1/1. In other words, the ratio of the amount of added base to the amount of base required to neutralize all carboxyl groups is 1/5 to 1/1. When all the carboxyl groups in the molecule are just neutralized, it is 1/1.

Examples of materials used for the neutralization of the carboxyl group include amines such as ammonia and triethanolamine, and hydroxides of alkali metals such as sodium hydroxide and calcium hydroxide.

In the acrylic adhesive having a carboxyl group in the molecule, by neutralizing at least a part of the carboxyl group, water can be mixed in the organic solvent solution of the adhesive, and an aqueous acrylic adhesive solution can be obtained. Therefore, the viscosity of the organic solvent solution of the adhesive can be increased. Thereby, even if the adhesive solution is directly applied to the fabric, it is possible to prevent the adhesive solution from oozing out from the back surface of the fabric.

The addition amount of water mixed into the adhesive organic solvent solution can be appropriately adjusted according to the target viscosity, etc., for example, relative to 100 parts by mass of the adhesive organic solvent solution, preferably 1-50 parts by mass, more preferably 5-40 Mass parts. If it is less than 1 part by mass, an effective viscosity increase cannot be obtained, and if it exceeds 50 parts by mass, there is a risk of insolubilization of the adhesive in the organic solvent solution.

The acrylic adhesive in this embodiment can be obtained by, for example, a known polymerization method such as a solution polymerization method, an emulsion polymerization method, and a suspension polymerization method. In addition, it can be obtained by radical polymerization using a radical polymerization initiator such as a peroxide-based compound or an azo-based compound.

The adhesive layer in this embodiment contains an organic liquid component. This component imparts flexibility to the adhesive layer, exhibits good adhesion to the skin surface, and imparts less damage to the stratum corneum during peeling, and can suppress the pain associated with peeling. Furthermore, it not only has the function of adjusting the adhesive organic solvent solution to the target viscosity, but also has the function of suppressing the winding gap (deformation of the adhesive tape) when the semi-finished roll is heated and aging after being formed.

Such an organic liquid component is not particularly limited as long as it has affinity or compatibility with the acrylic adhesive. For example, phthalic acid, maleic acid, adipic acid, caprylic acid, capric acid, lauric acid, myristic acid, palmitic acid, stearic acid, oleic acid, or esters of various fatty acids and alkyl alcohols, and ethyl acetate can be used. Polyol esters such as glycol, glycerin, trimethylolpropane, sorbitol anhydride, etc.

More specifically, as monohydric alcohol esters, diethyl phthalate, dibutyl phthalate, di(2-ethylhexyl) phthalate, dibutyl maleate can be cited , Dibutyl adipate, di(2-ethylhexyl) sebacate, ethyl myristate, isopropyl myristate, octyl lauryl myristate, isopropyl palmitate, Butyl stearate, isopropyl isostearate, hexyl laurate, cetyl lactate, myristyl lactate, octyl lauryl oleate, hexyl decyl dimethyl octanoate, 2-ethyl Cetyl hexanoate, isocetyl 2-ethylhexanoate, stearyl 2-ethylhexanoate, dioctyl succinate, etc.

In addition, as the esters of polyhydric alcohols, propylene glycol dicaprylate, propylene glycol dicaprate, propylene glycol diisostearate, glycerol monocaprylate, glyceryl tricaprylate, and glycerol tri-2-ethyl ester can be mentioned. Caproate, glyceryl tricaprate, triglyceryl laurate, glyceryl triisostearate, glycerol monooleate, glycerol trioleate, trimethylolpropane tri-2-ethylhexanoate , Sorbitan monolaurate, sorbitan monooleate, sorbitan trioleate, etc.

Among them, from the viewpoint of the ease of adjusting the viscosity of the adhesive solution, it is suitable to use an organic liquid component whose viscosity at room temperature is preferably 50 to 500 mPa·s, and more preferably 100 to 500 mPa·s. As such organic liquid components, for example, glycerol fatty acid esters such as glycerol monooleate, sorbitan fats such as sorbitan monolaurate, sorbitan monooleate, and sorbitan trioleate are suitably used. Acid ester. These components can be used alone or in combination of two or more. Furthermore, the room temperature in this embodiment means 1-30°C.

The content of the organic liquid component in the adhesive layer is relative to 100 parts by mass of the acrylic adhesive, and the upper limit is preferably 120 parts by mass, more preferably 100 parts by mass, and still more preferably 80 parts by mass.

The content of the organic liquid component in the adhesive layer is relative to 100 parts by mass of the acrylic adhesive, and the lower limit is preferably 20 parts by mass, more preferably 30 parts by mass, and still more preferably 40 parts by mass.

If the content of the component is within the above range, sufficient flexibility can be imparted to the adhesive layer. Therefore, it has good skin adhesion, and can suppress physical skin irritation or pain when peeling from the skin, and achieve good peeling properties.

In the adhesive layer of this embodiment, various plasticizers or softeners, fillers, stabilizers, antioxidants, antibacterial agents, bactericides, etc. can also be appropriately blended as needed without departing from the purpose of the present invention. additive.

In order to impart a moderate cohesive force, it is preferable to perform a cross-linking treatment on the adhesive layer of this embodiment. As the crosslinking treatment, in addition to physical treatment such as gamma-ray irradiation and electron beam irradiation, organic peroxides, isocyanate compounds, organic metal salts, metal alcoholates, metal chelate compounds, epoxy compounds, Chemical cross-linking treatment of compounds containing primary amine groups.

Specific examples of chemical crosslinking treatment include organic peroxides such as benzyl peroxide, isocyanate compounds such as toluene diisocyanate and hexamethylene diisocyanate, glycerol triglycidyl ether, and triglycidyl isocyanurate. Such as epoxy compounds, tris (acetone) aluminum, and metal chelate compounds such as ethyl aluminum diisopropyl acetate.

Among these, it is preferable to use an isocyanate compound, a metal alcoholate, a metal chelate compound, and an epoxy compound in terms of crosslinking reactivity and ease of handling. By using such a compound for cross-linking treatment, the balance of characteristics such as flexibility and cohesive force of the adhesive layer can be appropriately adjusted, so that the paste residue at the time of peeling can be suppressed.

The thickness of the adhesive layer is not particularly limited, and can be appropriately set according to the use of the medical adhesive tape or sheet of the present embodiment, or the application site of the skin surface to be attached.

Specifically, the upper limit of the thickness of the adhesive layer is preferably 100 μm, more preferably 80 μm. In addition, the lower limit of the thickness of the adhesive layer is preferably 10 μm, more preferably 20 μm. If the thickness of the adhesive layer is within the above range, it has good skin adhesion when applied to the skin, and excellent water vapor permeability can be obtained. Even if it is adhered for a long time, it can suppress the sultry or itching sensation as much as possible ( pruritus) and so on.

The medical adhesive tape or sheet of the present embodiment can also be formed with holes or suture holes in terms of preventing stuffiness or itching during the process of sticking to the skin surface, or improving hand-tearability. The holes or suture holes formed in the medical adhesive tape or sheet can be easily obtained by implementing well-known porous techniques such as metal rolls, punching machines, and laser irradiation.

In addition, as a method for forming holes or suture holes in the medical adhesive tape or sheet of this embodiment, the adhesive layer may be formed after the holes or suture holes are formed on the fabric, or the holes may be formed after the adhesive layer is formed on the fabric. Or suture hole. Furthermore, when a hole or a suture hole is formed after the adhesive layer is formed on the fabric, a hole or a suture hole penetrating the fabric and the adhesive layer is formed.

The medical adhesive tape or sheet of the present embodiment can be used in the form of being attached to, for example, medical tubes, catheters, medical equipment, various portable equipment (wearable equipment), or components constituting them. In addition, it is also suitable for the purposes of fixing, joining, decorating, protecting, and supporting the above-mentioned equipment or components.

In other words, using medical adhesive tapes or sheets, it is possible to fix, join, decorate, protect, support, etc. on the skin for medical tubes, catheters, medical devices, various portable devices (wearable devices), or components constituting them. .

The medical adhesive tape or sheet of this embodiment can be made into a wound body wound in a roll shape. In this case, it is preferable to perform a peeling treatment (back surface treatment) on the surface of the fabric on the opposite side to the surface with the adhesive layer. [Example]

Hereinafter, examples will be given to explain the present invention more specifically, but the present invention is not limited to these examples. Furthermore, hereinafter, "parts" and "%" mean "parts by mass" and "% by mass", respectively.

(Example 1) A monomer mixture containing 95 parts of 2-ethylhexyl acrylate and 5 parts of acrylic acid was solution polymerized in ethyl acetate to obtain an acrylic adhesive solution. With respect to 100 parts of the solid content of the obtained acrylic adhesive solution, 10 parts of 30% ammonia water is added, 40 parts of sorbitan trioleate, and triglycidyl isocyanurate as a crosslinking agent are added 0.1 part and water are stirred to prepare an aqueous acrylic adhesive solution with a water content of 15%.

The aqueous acrylic adhesive solution obtained above was applied to a cloth containing polyester fiber mixed wood pulp (impregnated with acrylate and styrene resin) so that the thickness of the dried adhesive layer became 50 μm. The non-woven fabric (bulk density: 0.393 g/cm ³ , basis weight: 35.4 g/m ² , thickness: 90 μm, air permeability: 0.6 seconds), dried at 120°C for 5 minutes to form an adhesive layer, and then wound on The core was formed into a semi-finished roll, and it was heated and aged at 50°C for 7 days to obtain a wound body of the adhesive tape for medical use.

(Example 2) In Example 1, the fabric was changed to a non-woven fabric (bulk density: 0.381 g/cm ³ , basis weight: 36.2 g) containing polyester fiber mixed wood pulp (impregnated with acrylate and styrene resin) /m ² , thickness: 95 μm, air permeability: 0.5 seconds), except for this, the medical adhesive tape wound body was obtained in the same manner as in Example 1.

(Example 3) In Example 1, the fabric was changed to a non-woven fabric (bulk density: 0.356 g/cm ³ , basis weight: 35.6 g) containing polyester fiber mixed wood pulp (impregnated with acrylate and styrene resin) /m ² , thickness: 100 μm, air permeability: 0.5 seconds), except for this, the medical adhesive tape wound body was obtained in the same manner as in Example 1.

(Example 4) In Example 1, the fabric was changed to a non-woven fabric (bulk density: 0.343 g/cm ³ , basis weight: 36.0 g/m ² , thickness: 105 μm) containing pulp (impregnated with acrylic resin) Air permeability: 0.5 seconds). Except for this, the medical adhesive tape wound body was obtained in the same manner as in Example 1.

(Comparative Example 1) In Example 1, the fabric was changed to a non-woven fabric (bulk density: 0.413 g/cm ³ , basis weight: 35 g) containing polyester fiber mixed wood pulp (impregnated with acrylic ester and styrene resin) /m ² , thickness: 84.8 μm, air permeability: 0.9 seconds), except for this, the medical adhesive tape wound body was obtained in the same manner as in Example 1.

(Comparative Example 2) In Example 1, the fabric was changed to polyester non-woven fabric (Sontara 8010 manufactured by DuPont, bulk density: 0.119 g/cm ³ , basis weight: 44 g/m ² , thickness: 370 μm, Air permeability: 0.1 second), except for this, in the same manner as in Example 1, a wound body of an adhesive tape for medical use was obtained.

(Appearance evaluation) In each example and each comparative example, when the aqueous acrylic adhesive solution was applied to the fabric, it was observed whether or not the adhesive oozes from the back surface of the fabric. In addition, the wound body of the medical adhesive tape of each example and each comparative example was heated and aged at 50°C for 7 days. When stored at 5°C, it was observed for appearance defects such as winding gaps or uneven thickness. Determine the appearance defect rate. The results are shown in Table 1.

[Table 1] Adhesive exudation Appearance defect rate Example 1 no 0% Example 2 no 0% Example 3 no 0% Example 4 no 0% Comparative example 1 no 14% Comparative example 2 Have 0%

According to Table 1 and Figure 1, it can be clearly seen that the medical adhesive tape rolls of Examples 1 to 4 did not have poor appearance such as winding gaps or uneven thickness, and there was no adhesive exudation from the back of the fabric. Excellent appearance. On the other hand, according to Table 1 and Fig. 2, it can be seen that the wound body of the adhesive tape for medical use of Comparative Example 1 has a winding gap or uneven thickness, and the appearance is poor. In addition, as shown in Table 1, in Comparative Example 2, the adhesive exuded from the back surface of the fabric.

Above, various embodiments have been described with reference to the drawings, but of course, the present invention is not limited to these examples. The industry understands that various alterations or amendments can be conceived within the scope of the scope of the patent application, and it is understood that these naturally belong to the technical scope of the present invention. In addition, it is also possible to arbitrarily combine the constituent elements in the above-mentioned embodiments within the scope not departing from the gist of the invention.

In addition, this application is based on the Japanese patent application (Japanese Patent Application No. 2019-164872) filed on September 10, 2019, and the content is incorporated into this application as a reference. [Industrial availability]

According to the present invention, it is possible to provide a method that can prevent the adhesive solution from oozing out from the back of the fabric even if the adhesive solution is directly applied to the fabric, and even if it is heated and aged after being formed into a semi-finished roll, it will not be used in the semi-finished roll. A medical adhesive tape or sheet with a good appearance due to winding gaps.

FIG. 1 is a photograph of the appearance of the wound body of the adhesive tape for medical use obtained in Example 2. FIG. Figure 2 is a photograph of the appearance of the wound medical adhesive tape obtained in Comparative Example 1.

Claims (8)

A medical adhesive tape or sheet, which has an adhesive layer on at least one side of a cloth, and the adhesive layer contains an acrylic adhesive with a carboxyl group in the molecule and at least a part of the carboxyl group is neutralized, and an organic For the liquid component, the bulk density of the above-mentioned fabric is 0.15 to 0.40 g/cm ³ . Such as the medical adhesive tape or sheet of claim 1, wherein the bulk density of the above-mentioned fabric is 0.30～0.40 g/cm ³ . The medical adhesive tape or sheet of claim 1 or 2, wherein the content of the organic liquid component in the adhesive layer is 20 to 120 parts by mass relative to 100 parts by mass of the acrylic adhesive. The medical adhesive tape or sheet according to any one of claims 1 to 3, wherein the organic liquid component is glycerin fatty acid ester or sorbitan fatty acid ester. The medical adhesive tape or sheet according to any one of claims 1 to 4, wherein 1/5 to 1/1 of the carboxyl groups in the acrylic adhesive are neutralized. The medical adhesive tape or sheet according to any one of claims 1 to 5, wherein the content of the monomer having a carboxyl group in the molecule is 1 to 20 parts by mass relative to 100 parts by mass of all monomers constituting the acrylic adhesive. Such as the medical adhesive tape or sheet of any one of claims 1 to 6, wherein the air permeability of the fabric is 0.6 seconds or less. An adhesive tape or sheet wound body for medical use, which is wound with the adhesive tape or sheet for medical use according to any one of Claims 1 to 7.

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