TW200727922A - Solid dosage formulations of narcotic drugs having improved buccal adsorption - Google Patents
Solid dosage formulations of narcotic drugs having improved buccal adsorptionInfo
- Publication number
- TW200727922A TW200727922A TW095126670A TW95126670A TW200727922A TW 200727922 A TW200727922 A TW 200727922A TW 095126670 A TW095126670 A TW 095126670A TW 95126670 A TW95126670 A TW 95126670A TW 200727922 A TW200727922 A TW 200727922A
- Authority
- TW
- Taiwan
- Prior art keywords
- solid dosage
- dosage formulations
- narcotic drugs
- adsorption
- improved buccal
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4468—Non condensed piperidines, e.g. piperocaine having a nitrogen directly attached in position 4, e.g. clebopride, fentanyl
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- Pain & Pain Management (AREA)
- Neurosurgery (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Anesthesiology (AREA)
- Rheumatology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11/186,925 US20070020186A1 (en) | 2005-07-22 | 2005-07-22 | Solid dosage formulations of narcotic drugs having improved buccal adsorption |
Publications (1)
Publication Number | Publication Date |
---|---|
TW200727922A true TW200727922A (en) | 2007-08-01 |
Family
ID=37440618
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TW095126670A TW200727922A (en) | 2005-07-22 | 2006-07-21 | Solid dosage formulations of narcotic drugs having improved buccal adsorption |
Country Status (26)
Country | Link |
---|---|
US (3) | US20070020186A1 (zh) |
EP (1) | EP1906961B1 (zh) |
JP (1) | JP5714797B2 (zh) |
KR (1) | KR101326206B1 (zh) |
CN (1) | CN101208091A (zh) |
AU (1) | AU2006271870B2 (zh) |
BR (1) | BRPI0613769A2 (zh) |
CA (1) | CA2607360C (zh) |
CY (1) | CY1117470T1 (zh) |
DK (1) | DK1906961T3 (zh) |
ES (1) | ES2569228T3 (zh) |
HR (1) | HRP20160327T1 (zh) |
HU (1) | HUE027354T2 (zh) |
IL (1) | IL187387A (zh) |
MA (1) | MA29744B1 (zh) |
MX (1) | MX2007015480A (zh) |
NO (1) | NO20080827L (zh) |
NZ (1) | NZ563511A (zh) |
PL (1) | PL1906961T3 (zh) |
RS (1) | RS54670B1 (zh) |
RU (1) | RU2408373C2 (zh) |
SI (1) | SI1906961T1 (zh) |
TW (1) | TW200727922A (zh) |
UA (1) | UA90518C2 (zh) |
WO (1) | WO2007009806A2 (zh) |
ZA (1) | ZA200710406B (zh) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8852638B2 (en) | 2005-09-30 | 2014-10-07 | Durect Corporation | Sustained release small molecule drug formulation |
US8497258B2 (en) | 2005-11-12 | 2013-07-30 | The Regents Of The University Of California | Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract |
US8252328B2 (en) * | 2006-01-06 | 2012-08-28 | Acelrx Pharmaceuticals, Inc. | Bioadhesive drug formulations for oral transmucosal delivery |
US8202535B2 (en) * | 2006-01-06 | 2012-06-19 | Acelrx Pharmaceuticals, Inc. | Small-volume oral transmucosal dosage forms |
US9066847B2 (en) * | 2007-01-05 | 2015-06-30 | Aceirx Pharmaceuticals, Inc. | Storage and dispensing devices for administration of oral transmucosal dosage forms |
US8357114B2 (en) | 2006-01-06 | 2013-01-22 | Acelrx Pharmaceuticals, Inc. | Drug dispensing device with flexible push rod |
US8865743B2 (en) | 2006-01-06 | 2014-10-21 | Acelrx Pharmaceuticals, Inc. | Small volume oral transmucosal dosage forms containing sufentanil for treatment of pain |
US8535714B2 (en) | 2006-01-06 | 2013-09-17 | Acelrx Pharmaceuticals, Inc. | Small volume oral transmucosal dosage forms containing sufentanil for treatment of pain |
US8753308B2 (en) | 2006-01-06 | 2014-06-17 | Acelrx Pharmaceuticals, Inc. | Methods for administering small volume oral transmucosal dosage forms using a dispensing device |
US9289583B2 (en) * | 2006-01-06 | 2016-03-22 | Acelrx Pharmaceuticals, Inc. | Methods for administering small volume oral transmucosal dosage forms using a dispensing device |
US8252329B2 (en) | 2007-01-05 | 2012-08-28 | Acelrx Pharmaceuticals, Inc. | Bioadhesive drug formulations for oral transmucosal delivery |
US20070260491A1 (en) * | 2006-05-08 | 2007-11-08 | Pamela Palmer | System for delivery and monitoring of administration of controlled substances |
US20070299687A1 (en) * | 2006-06-23 | 2007-12-27 | Pamela Palmer | Inpatient system for patient-controlled delivery of oral transmucosal medications dosed as needed |
MX337286B (es) | 2007-05-25 | 2016-02-22 | Indivior Uk Ltd | Formulaciones de transferencia sostenida de compuestos de risperidona. |
US8945592B2 (en) | 2008-11-21 | 2015-02-03 | Acelrx Pharmaceuticals, Inc. | Sufentanil solid dosage forms comprising oxygen scavengers and methods of using the same |
US20110097401A1 (en) * | 2009-06-12 | 2011-04-28 | Meritage Pharma, Inc. | Methods for treating gastrointestinal disorders |
GB2481017B (en) | 2010-06-08 | 2015-01-07 | Rb Pharmaceuticals Ltd | Microparticle buprenorphine suspension |
US9272044B2 (en) | 2010-06-08 | 2016-03-01 | Indivior Uk Limited | Injectable flowable composition buprenorphine |
RU2476209C1 (ru) * | 2012-02-29 | 2013-02-27 | Станислав Анатольевич Кедик | Имплантируемое лекарственное средство на основе налтрексона для лечения пациентов, зависимых от алкоголя или опиатов |
BR112014024382B1 (pt) | 2012-04-18 | 2022-08-09 | SpecGx LLC | Composições farmacêuticas de contenção de abuso de liberação imediata e seu processo de preparação |
MX362838B (es) * | 2012-07-12 | 2019-02-19 | SpecGx LLC | Composiciones farmacéuticas de liberación prolongada para disuadir el abuso de opioides que comprenden un plastómero, un elastómero y un plastificante delicuescente. |
GB201404139D0 (en) | 2014-03-10 | 2014-04-23 | Rb Pharmaceuticals Ltd | Sustained release buprenorphine solution formulations |
MY187877A (en) | 2014-12-23 | 2021-10-26 | Acelrx Pharmaceuticals Inc | Systems, devices and methods for dispensing oral transmucosal dosage forms |
EP3856160A4 (en) | 2018-09-25 | 2022-07-06 | SpecGx LLC | ANTI-ABUSE IMMEDIATE RELEASE CAPSULES DOSAGE FORMS |
Family Cites Families (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5785989A (en) | 1985-05-01 | 1998-07-28 | University Utah Research Foundation | Compositions and methods of manufacturing of oral dissolvable medicaments |
US5464632C1 (en) | 1991-07-22 | 2001-02-20 | Prographarm Lab | Rapidly disintegratable multiparticular tablet |
JP3069458B2 (ja) | 1992-01-29 | 2000-07-24 | 武田薬品工業株式会社 | 口腔内崩壊型錠剤およびその製造法 |
US5576014A (en) | 1994-01-31 | 1996-11-19 | Yamanouchi Pharmaceutical Co., Ltd | Intrabuccally dissolving compressed moldings and production process thereof |
US5888534A (en) | 1995-06-13 | 1999-03-30 | Pentech Pharmaceuticals, Inc. | Controlled release of drugs delivered by sublingual or buccal administration |
US5624677A (en) | 1995-06-13 | 1997-04-29 | Pentech Pharmaceuticals, Inc. | Controlled release of drugs delivered by sublingual or buccal administration |
GB9517062D0 (en) | 1995-08-18 | 1995-10-25 | Scherer Ltd R P | Pharmaceutical compositions |
KR20000022239A (ko) * | 1996-07-11 | 2000-04-25 | 토마스 헤인 | 인돌 선택성 세로토닌 작용약을 함유한 내포 복합체 |
JP3770666B2 (ja) * | 1996-09-20 | 2006-04-26 | 株式会社ティ・ティ・エス技術研究所 | 経粘膜吸収製剤用組成物 |
EP0839526A3 (en) | 1996-10-31 | 1999-01-07 | Takeda Chemical Industries, Ltd. | Solid pharmaceutical preparation with fast buccal disintegration or dissolution |
US6024981A (en) | 1997-04-16 | 2000-02-15 | Cima Labs Inc. | Rapidly dissolving robust dosage form |
AU8977698A (en) | 1997-07-25 | 1999-02-16 | Elan Corporation, Plc | A process for the preparation of a granulate suitable to the preparation of rapidly disintegrable mouth-soluble tablets |
US5869098A (en) | 1997-08-20 | 1999-02-09 | Fuisz Technologies Ltd. | Fast-dissolving comestible units formed under high-speed/high-pressure conditions |
US20030082107A1 (en) * | 1997-10-01 | 2003-05-01 | Dugger Harry A. | Buccal, polar and non-polar spray or capsule containing drugs for treating an infectious disease or cancer |
US6350470B1 (en) | 1998-04-29 | 2002-02-26 | Cima Labs Inc. | Effervescent drug delivery system for oral administration |
US6200604B1 (en) * | 1998-03-27 | 2001-03-13 | Cima Labs Inc. | Sublingual buccal effervescent |
US6974590B2 (en) | 1998-03-27 | 2005-12-13 | Cima Labs Inc. | Sublingual buccal effervescent |
US6270790B1 (en) | 1998-08-18 | 2001-08-07 | Mxneil-Ppc, Inc. | Soft, convex shaped chewable tablets having reduced friability |
US6680071B1 (en) | 1999-03-03 | 2004-01-20 | R. P. Scherer Technologies, Inc. | Opioid agonist in a fast dispersing dosage form |
JP2000281589A (ja) | 1999-03-26 | 2000-10-10 | T T S Gijutsu Kenkyusho:Kk | 経粘膜吸収助剤 |
US6210699B1 (en) | 1999-04-01 | 2001-04-03 | Watson Pharmaceuticals, Inc. | Oral transmucosal delivery of drugs or any other ingredients via the inner buccal cavity |
US6264981B1 (en) | 1999-10-27 | 2001-07-24 | Anesta Corporation | Oral transmucosal drug dosage using solid solution |
US20030104041A1 (en) * | 1999-12-16 | 2003-06-05 | Tsung-Min Hsu | Transdermal and topical administration of drugs using basic permeation enhancers |
US20020013331A1 (en) * | 2000-06-26 | 2002-01-31 | Williams Robert O. | Methods and compositions for treating pain of the mucous membrane |
US6733781B2 (en) | 2000-12-06 | 2004-05-11 | Wyeth | Fast dissolving tablet |
US20030215502A1 (en) * | 2002-03-20 | 2003-11-20 | Elan Pharma International Limited | Fast dissolving dosage forms having reduced friability |
CA2479098A1 (en) * | 2002-03-20 | 2003-09-25 | Maree Therese Smith | Methods and compositions comprising nitric oxide donors and opioid analgesics |
US20040253307A1 (en) * | 2003-02-04 | 2004-12-16 | Brian Hague | Sugar-free oral transmucosal solid dosage forms and uses thereof |
US20040202698A1 (en) | 2003-04-02 | 2004-10-14 | The Procter & Gamble Company | Drug delivery systems comprising an encapsulated active ingredient |
JP4739217B2 (ja) * | 2003-05-07 | 2011-08-03 | サムヤン コーポレイション | 速く溶ける錠剤を製造するための高可塑性顆粒 |
ATE498395T1 (de) * | 2003-12-31 | 2011-03-15 | Cima Labs Inc | Allgemein lineare brauseform von fentanyl zur oralen anwendung und verfahren zur verabreichung |
-
2005
- 2005-07-22 US US11/186,925 patent/US20070020186A1/en not_active Abandoned
-
2006
- 2006-07-21 CN CNA2006800232888A patent/CN101208091A/zh active Pending
- 2006-07-21 UA UAA200713973A patent/UA90518C2/ru unknown
- 2006-07-21 US US11/490,500 patent/US8574552B2/en active Active
- 2006-07-21 EP EP06776336.7A patent/EP1906961B1/en active Active
- 2006-07-21 CA CA2607360A patent/CA2607360C/en active Active
- 2006-07-21 NZ NZ563511A patent/NZ563511A/en not_active IP Right Cessation
- 2006-07-21 BR BRPI0613769-5A patent/BRPI0613769A2/pt not_active Application Discontinuation
- 2006-07-21 KR KR1020087000576A patent/KR101326206B1/ko active Active
- 2006-07-21 TW TW095126670A patent/TW200727922A/zh unknown
- 2006-07-21 SI SI200632040A patent/SI1906961T1/sl unknown
- 2006-07-21 AU AU2006271870A patent/AU2006271870B2/en not_active Ceased
- 2006-07-21 MX MX2007015480A patent/MX2007015480A/es active IP Right Grant
- 2006-07-21 HU HUE06776336A patent/HUE027354T2/en unknown
- 2006-07-21 PL PL06776336T patent/PL1906961T3/pl unknown
- 2006-07-21 RS RS20160214A patent/RS54670B1/en unknown
- 2006-07-21 RU RU2007149044/15A patent/RU2408373C2/ru active
- 2006-07-21 WO PCT/EP2006/007189 patent/WO2007009806A2/en active Application Filing
- 2006-07-21 JP JP2008521904A patent/JP5714797B2/ja active Active
- 2006-07-21 DK DK06776336.7T patent/DK1906961T3/en active
- 2006-07-21 ES ES06776336.7T patent/ES2569228T3/es active Active
-
2007
- 2007-11-15 IL IL187387A patent/IL187387A/en not_active IP Right Cessation
- 2007-11-30 ZA ZA200710406A patent/ZA200710406B/xx unknown
-
2008
- 2008-02-15 NO NO20080827A patent/NO20080827L/no not_active Application Discontinuation
- 2008-02-18 MA MA30659A patent/MA29744B1/fr unknown
-
2013
- 2013-09-04 US US14/017,642 patent/US10258693B2/en active Active
-
2016
- 2016-04-01 HR HRP20160327TT patent/HRP20160327T1/hr unknown
- 2016-04-26 CY CY20161100346T patent/CY1117470T1/el unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
TW200727922A (en) | Solid dosage formulations of narcotic drugs having improved buccal adsorption | |
IL175380A0 (en) | Ophthalmologic pharmaceutical compositions containing a hydroxylamine compound | |
SG131857A1 (en) | δD-CRYSTALLINE FORM OF IV ABRADINE HYDROCHLORIDE, A PROCESS FOR ITS PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT | |
MX2008002492A (es) | Composiciones farmaceuticas que comprenden un farmaco dependiente del ph, un modificador del ph, y un agente retardante. | |
TW200621737A (en) | 2-carbamide-4-phenylthiazole derivatives, preparation thereof and therapeutic use thereof | |
ZA200801991B (en) | Novel camptothecin analogues compounds, a method for the preparation thereof and pharmaceutical compositions containing said compounds | |
TW200640861A (en) | Amorphous lercanidipine hydrochloride | |
RS98704A (en) | New pharmaceutical compositions containing flibanserin polymorpha | |
TW200718698A (en) | Process for preparing new tiotropium salts, new tiotropium salts as such and pharmaceutical compositions thereof | |
HK1096386A1 (en) | Indanyl-piperazine compounds, a process for their preparation and pharmaceutical compositions containing them | |
ZA200603810B (en) | Phenylpyridylpiperazine compounds, a process for their preparation and pharmaceutical compositions containing them | |
HK1096097A1 (en) | Phenylpyridylpiperazine compounds, a process for their preparation and pharmaceutical compositions containing them | |
HK1093986A1 (en) | Piperazine compounds, a process for their preparation and pharmaceutical compositions containing them | |
ZA200402657B (en) | Isoquinoline compounds, a process for their preparation and pharmaceutical compositions containing them. | |
TW200633717A (en) | Process for and intermediates in the preparation of canfosfamide and its salts, pharmaceutical compositions containing some intermediates, and their use as anticancer agents | |
ZA200606277B (en) | Polysubstituted 1,1-pyridyloxycyclopropanamine compounds, a process for their preparation and pharmaceutical compositions containing them | |
ZA200606276B (en) | Polysubstituted 1,1-pyridylaminocyclopropanamine compounds, a process for their preparation and pharmaceutical compositions containing them | |
ZA200501010B (en) | BenzoÄBÜchromeno-naphthyridin-7-one and pyranoÄ2'3':7,8ÜquinoÄ2,3-BÜquinoxalin-7-one compounds, process for their preparation and pharmaceutical compositions containing them. | |
ZA200800833B (en) | New 1H-indole-pyridinecarboxamide and 1H-indolepiperidinecarboxamide compounds, a process for their preparation and pharmaceutical compositions containing them | |
SG110170A1 (en) | New benzoindoline compounds, a process for their preparation and pharmaceutical compositions containing them | |
HK1123048A1 (en) | Novel camptothecin analogues compounds, a method for the preparation thereof and pharmaceutical compositions containing said compounds | |
HK1079775A1 (en) | New 4-oxo-4,6,7,8-tetrahydro-pyrrolo Ä1,2-AÜpyrazine-6-carboxamide compounds, a process for their preparation and pharmaceutical compositions containing them | |
ZA200302392B (en) | Indoline compounds, a process for their preparation and pharmaceutical compositions containing them. |