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TR202019409A1 - AN ALCOHOL-BASED PRODUCT THAT DISINFECTS THE SKIN AND SUPPORTS THE SKIN FLORA - Google Patents

AN ALCOHOL-BASED PRODUCT THAT DISINFECTS THE SKIN AND SUPPORTS THE SKIN FLORA

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Publication number
TR202019409A1
TR202019409A1 TR2020/19409A TR202019409A TR202019409A1 TR 202019409 A1 TR202019409 A1 TR 202019409A1 TR 2020/19409 A TR2020/19409 A TR 2020/19409A TR 202019409 A TR202019409 A TR 202019409A TR 202019409 A1 TR202019409 A1 TR 202019409A1
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Turkey
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weight
alcohol
based product
product according
moisturizing agent
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TR2020/19409A
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Turkish (tr)
Inventor
Askeroğlu Zeynep
Serhan Boduroğlu Mehmet
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Eczacibasi Tueketim Ueruenleri Sanayi Ve Ticaret Anonim Sirketi
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Priority to TR2020/19409A priority Critical patent/TR202019409A1/en
Priority to PCT/TR2021/051251 priority patent/WO2022119532A1/en
Priority to EP21901169.9A priority patent/EP4255448A4/en
Publication of TR202019409A1 publication Critical patent/TR202019409A1/en

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N31/00Biocides, pest repellants or attractants, or plant growth regulators containing organic oxygen or sulfur compounds
    • A01N31/02Acyclic compounds
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01PBIOCIDAL, PEST REPELLANT, PEST ATTRACTANT OR PLANT GROWTH REGULATORY ACTIVITY OF CHEMICAL COMPOUNDS OR PREPARATIONS
    • A01P1/00Disinfectants; Antimicrobial compounds or mixtures thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/14Quaternary ammonium compounds, e.g. edrophonium, choline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/3533,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A61K31/355Tocopherols, e.g. vitamin E
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716Glucans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/733Fructosans, e.g. inulin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/13Coniferophyta (gymnosperms)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/41Amines
    • A61K8/416Quaternary ammonium compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02Local antiseptics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005Antimicrobial preparations

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
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  • Natural Medicines & Medicinal Plants (AREA)
  • Birds (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pest Control & Pesticides (AREA)
  • Environmental Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Medical Informatics (AREA)
  • Plant Pathology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Dentistry (AREA)
  • Agronomy & Crop Science (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

Buluşun konusu, içeriğindeki alkolün buharlaşmasının ardından da cilt yüzeyine tutunup etkisini sürdürmeye devam ederek cildin dezenfekte edilmesini sağlayan ve aynı zamanda cilt florasını destekleyerek cildin tahriş olmasını önleyen alkol bazlı bir ürün ile ilgilidir. Buluş konusu alkol bazlı ürün temel olarak en az bir tür alkol bileşiği, alkol bileşiğinin buharlaşmasının ardından cilt yüzeyinde kalarak dezenfekte edici etki gösteren en az bir tür katyonik yüzey aktif madde, cilt florasında bulunan faydalı mikroorganizmaların çoğalmasını sağlayarak cilt florasını destekleyen en az bir tür prebiyotik içermektedir. Buluş konusu ürün cildin nem dengesinin korunmasını sağlayan nemlendirici maddelerle kullanılmaya da uygun içeriktedir.The subject of the invention relates to an alcohol-based product that maintains its effect on the skin surface after the evaporation of the alcohol in its content, ensures disinfection of the skin and at the same time prevents skin irritation by supporting the skin flora. The alcohol-based product of the invention basically contains at least one kind of alcohol compound, at least one kind of cationic surfactant that has a disinfecting effect by staying on the skin surface after the evaporation of the alcohol compound, and at least one kind of prebiotic that supports the skin flora by enabling the proliferation of beneficial microorganisms in the skin flora. . The product subject to the invention is also suitable for use with moisturizing agents that maintain the moisture balance of the skin.

Description

TARIFNAME CILDIN DEZENFEKTE EDILMESINI SAGLAYAN VE CILT FLORASINI DESTEKLEYEN ALKOL BAZLI BIR ÜRÜN Bulusun Konusu Bulusun konusu, içerigindeki alkolün buharlasmasinin ardindan da cilt yüzeyine tutunup etkisini sürdürmeye devam ederek cildin dezenfekte edilmesini saglayan ve ayni zamanda cilt florasini destekleyerek cildin tahris olmasini önleyen alkol bazli bir ürün ile Teknigin Bilinen Durumu Dis ortamla sürekli temas halinde olmasi sebebiyle cilt üzerinde çok sayida patojenik mikroorganizma birikmektedir. Ciltte ve vücudun herhangi bir bölgesinde görülen enfeksiyonlarin bazilari bahsedilen mikroorganizmalarin vücudun bu bölgelerine yayilmasiyla meydana gelmektedir. Dolayisiyla cildin düzenli olarak dezenfekte edilmesi, özellikle enfeksiyon hastaliklarinin önlenmesi için alinmasi gereken öncelikli önlemdir. Suya ulasilamayan seyahat kosullarinda veya diger toplu kullanim alanlarinda cildin yikanarak dezenfekte edilmesi mümkün olmamakta, ciltteki bakterilerin dezenfeksiyon ile etkisiz hale getirilmesi, ideal hijyen kosullarinin saglanmasi ve cilt sagliginin korunmasi için cilde pratik sekilde uygulanan, durulama ve kurulama gerektirmeyen antiseptiklere, dezenfektanlara ihtiyaç duyulmaktadir. Özellikle salgin dönemlerinde bu ihtiyaç oldukça artmaktadir. Bu tür dezenfekte edici ürünler özellikle toplu kullanim alanlarinda bulunan yüzeylere temas edilmesi ile ciltte biriken mikroorganizmalarin etkisiz hale getirilmesini, cilde yayilmasini, böylece bireyden bireye bulasmasinin önlenmesini saglamaktadir. Cilde uygulandiktan sonra durulama ve kurulama islemi gerektirmeyen bu tür dezenfektanlar kullanicilara kullanim kolayligi saglamakta, su sarfiyatini azaltmaktadir. Mevcut durumda cildin dezenfekte edilmesi amaciyla jel, köpük veya sivi formda alkol bazli veya alkol bazli olmayan antiseptikler, dezenfektanlar kullanilmaktadir. Alkol bazli antiseptikler, cilde uygulandiklarinda alkol bazli olmayan antiseptiklere kiyasla daha hizli ve etkili dezenfeksiyon saglamalari sebebiyle kullanicilar tarafindan daha fazla tercih edilmektelerdir. Ancak alkolün kisa sürede buharlasmasi sebebiyle bu etki kisa süreli olmaktadir ve ciltte kisa sürede yeniden patojenik mikroorganizmalar birikmeye baslamaktadir. Bu durum dezenfektanlarin devamli olarak kullanilmasina, dezenfektanlarin devamli kullanimi ise zehirlenmelere ve ciltteki dogal nemlendirici faktörlerin, yararli mikroorganizmalarin ve su içeriginin de azalmasina ve cildin dogal yapisinin bozulmasina yol açmaktadir. Cildin yapisinin bozulmasi nemlendirici etkiye sahip Iipitlerin de üretimini azaltmakta, cildin nem ihtiyaci lipitlerden de karsilanamaz hale gelmektedir. Su kaybi cildi kurutmakta, kuruyan ciltte kasinti, soyulma ve çatlaklar meydana gelmektedir. Çatlaklar, uzaklastirilmasi istenen patojenik mikroorganizmalarin barinmasi için uygun ortami olusturmakta, mikroorganizmalar açik yara niteligi tasiyan bu çatlaklarda birikerek zamanla enfeksiyona yol açmaktalardir. Bu sebeplerle ana bilesen olan alkolün buharlasmasinin ardindan da cildin dezenfekte edilmesi ve böylece dezenfektan kullaniminin sinirlandirilmasini saglamak amaciyla, cerrahi operasyon öncesinde hastanin cildine uygulandiginda operasyon sonrasinda ciltte enfeksiyon olusma riskini azalttigi tespit edilen katyonik yüzey aktif maddeleri içeren dezenfektanlara ihtiyaç duyulmaktadir. Katyonik yüzey aktif maddeler negatif yüklü mikroorganizma hücresinin yüzeyi ile etkilesime girerek hücre membraninin bütünlügünü bozmakta ve hücre içerisine penetre olarak hücre ölümüne sebep olmakta, böylece alkolün buharlasmasinin ardindan da ciltte bakteri, küf, mantar ve virüslerin birikmesini engellemektedir. Ancak yüzey aktif maddelerin ciltte uzun süre kalmasi ile cilt üzerinde bulunan patojenik mikroorganizmalar ile birlikte cildin florasini olusturan faydali mikroorganizmalar da aktivitesini kaybetmekte, cildin dogal yapisi bozulmaktadir. Bu durumda cildin dogal florasinin korunarak dezenfekte edilmesi için dezenfektan kullaniminin ardindan cilde, ikinci bir islem olarak cildin florasini destekleyici ilaveleri içeren bakim ürünleri uygulanmaktadir. Birden fazla ürünün kullanimi kullanicilariçin maliyetli olmakta, birden fazla islemin uygulanmasi ise zaman kaybi yaratmaktadir. Dolayisiyla pratik bir dezenfeksiyon islemi gerçeklestirilememektedir. Bu sebeple cildin dogal florasi korunarak dezenfekte edilmesini saglayan yüzey aktif madde içeren alkol bazli antiseptiklere, dezenfektanlara ihtiyaç duyulmaktadir. Mevcut durumda kullanilan kisa süre etkili alkol bazli dezenfektanlarin ve antiseptiklerin kullanimi ile ortaya çikan bahsedilen olumsuzluklarin ortadan kaldirilmasi amaciyla bulus kapsaminda alkolün buharlasmasinin ardindan da belirli bir süre boyunca cilde tutunarak ciltte patojenik mikroorganizmalarin birikmesini engelleyen yüzey aktif maddelerin yani sira cildin dogal florasinda bulunan yararli mikroorganizmalar için besin kaynagi olan ve böylece faydali mikroorganizmalarin gelisimini ve aktivitesini seçici olarak arttirarak cilt florasi için ideal kosullarin yaratilmasini saglayan en az bir prebiyotik ajani içeren alkol bazli bir ürün gelistirilmistir. Gelistirilen ürün cildin nem dengesinin korunmasini, böylece tahris edilmeden dezenfekte edilmesini saglayan nemlendirici maddeleri de içerebilmektedir. Böylece cildin dezenfekte edilmesi ve dogal florasinin desteklenmesi amaciyla birden fazla hijyen ve bakim ürününün birden fazla adimda cilde uygulanmasina gerek kalmamakta, cilt temizligi ve bakimi kullanicilara pratik kullanim imkani sunan, zaman kaybi yaratmayan, kolay üretilebilir, düsük maliyetli ve toplumun her kesimi tarafindan kolay erisilebilir olan tek bir ürün ile ve tek bir adimda uygulama ile yapilmaktadir. Bulusun Amaci Bulusun amaci, içerigindeki alkolün buharlasmasinin ardindan da cilde tutunarak etkisini sürdürmeye devam ederek cildin dezenfekte edilmesini saglayan alkol bazli bir ürün gelistirmektir. Bulusun baska bir amaci, cildin dogal florasinda bulunan yararli mikroorganizmalarin gelisimini ve aktivitesini seçici olarak arttirarak ciltte enfeksiyon olusma riskini ortadan kaldiran, cilt florasini destekleyen alkol bazli bir ürün gelistirmektir. Bulusun baska bir amaci, cildin dezenfekte edilirken nemlendirilmesini saglayan, böylece ciltte kuruluk, çatlak ve yanma gibi belirtilerin yasanmasi riskini ortadan kaldiran nemlendirici maddelerle kullanilmaya uygun içerige sahip alkol bazli bir ürün gelistirmektir. Bulusun baska bir amaci, bulusun önceki amaçlarinda belirtilen özelliklere sahip bir el antiseptigi gelistirmektir. Bulusun Açiklamasi Bulusun konusu, içerigindeki alkolün buharlasmasinin ardindan da cilt yüzeyine tutunup etkisini sürdürmeye devam ederek cildin dezenfekte edilmesini saglayan ve ayni zamanda cilt florasini destekleyerek cildin tahris olmasini önleyen alkol bazli bir ürün ile Bulus konusu alkol bazli ürün temel olarak en az bir tür alkol bilesigi, alkol bilesiginin buharlasmasinin ardindan cilt yüzeyinde kalarak dezenfekte edici etki gösteren en az bir tür katyonik yüzey aktif madde, cilt florasinda bulunan faydali mikroorganizmalarin çogalmasini saglayarak cilt florasini destekleyen en az bir tür prebiyotik içermektedir. Bulus konusu ürün tercih edilen bir uygulamasinda temel bilesenlere ilave olarak cildin nem dengesinin korunmasini saglayan en az bir tür nemlendirici madde içermektedir. Bulus konusu ürün agirlikça % 60-93 oraninda, tercihen agirlikça % 65-75 oraninda, hizli ve etkili dezenfeksiyon sagladiklari bilinen izopropil alkol ve etil alkol arasindan seçilen en az bir tür alkol, tercihen etil alkol içermektedir. Bulus konusu ürünün elde edilmesinde kullanilacak olan yüzey aktif maddenin tespit edilebilmesi amaciyla agirlikça % 60-93 oraninda, tercihen agirlikça % 65-75 oraninda en az bir tür alkole, tercihen etil alkole ilave olarak degisen miktarlarda, tercihen klorheksidin glukonat veya kuaterner amonyum bilesikleri olan benzetonyum klorür, benzalkonyum klorür, dodesiltrimetil amonyum klorür, dodesil benzildimetil amonyum klorür, kokobenzildimetil amonyum klorür veya didesildimetil amonyum klorür bilesikleri arasindan seçilen en az bir tür katyonik yüzey aktif madde ilave edilerek kompozisyonlar hazirlanmistir. Elde edilen kompozisyonlarin alkolün buharlasmasindan sonra cilde tutunma performanslari ve etki süreleri degerlendirilmistir. Yapilan degerlendirmeler sonucunda ise nihai ürünün elde edilmesinde kullanilacak yüzeye tutunma performansi yüksek yüzey aktif madde/maddeler belirlenmistir. Kuaterner amonyum yapili katyonik yüzey aktif maddelerden benzalkonyum klorürün ciltte ve cansiz yüzeylerde bulunan birçok mikroorganizma türünü yüksek oranda dezenfekte ettigi bilinmektedir. Farkli uzunlukta ve farkli oranlarda karbon zinciri dagilimlarina sahip benzalkonyum klorür bilesikleri bulunmaktadir. 14 ve 16 karbonlu karbon Zincirlerini içeren bilesiklerin dezenfekte edici etkisi daha fazladir. Baska bir ifadeyle yüksek miktarda 14 karbonlu ve 16 karbonlu benzalkonyum klorür bilesikleri, içerdikleri karbon zincirlerinin uzunluklari bakimindan düsük miktarda kullanilmalariyla dahi hedeflenen etkinin elde edilmesinde yeterli olmaktalardir. 14 karbonlu karbon zincirini içeren bilesigin etkinligi de 16 karbonlu karbon zincirini içeren bilesikten daha yüksektir. Yani dezenfekte edici etki zincir uzunluguna, belirli uzunluktaki zincirin miktarina ve belirli uzunluktaki zincirin etki ettigi mikroorganizma türüne göre degisiklik göstermektedir. Bu sebeple bazi kompozisyonlarin hazirlanmasinda benzalkonyum klorür bilesiklerinden agirlikça % 62-75 oraninda 12 karbonlu karbon zincirini, agirlikça karbon zincirini içeren benzalkonyum klorür bilesigini ve agirlikça % 50 oraninda 12 karbonlu karbon zincirini, agirlikça % 30 oraninda 14 karbonlu karbon zincirini, agirlikça zincirini içeren benzalkonyum klorür bilesikleri kullanilmistir. Didesildimetil amonyum klorür ve benzalkonyum klorürün patojenik mikroorganizmalar üzerindeki etkileri mikroorganizma türüne göre farklilik göstermektedir. Baska bir ifadeyle bazi mikroorganizmalar üzerinde benzalkonyum klorür daha etkinken, bazi mikroorganizmalar üzerinde ise didesil dimetil amonyum klorür daha etkindir. Bu nedenle didesildimetil amonyum klorür ve benzalkonyum klorürün bir arada kullanilmasinin nihai ürünlerin etkinlik alanini genisletilecegi düsünülerek iki yüzey aktif maddeyi farkli oranlarda içeren kompozisyonlar hazirlanmistir. 1 numarali kompozisyon agirlikça % 65-75 oraninda etil alkol ve agirlikça % 0,05-5 oraninda, tercihen agirlikça % 1-2 oraninda klorheksidin glukonat içermektedir. 2 numarali kompozisyon agirlikça % 65-75 oraninda etil alkol ve agirlikça % 0,05-5 oraninda, tercihen % O,4-0,6 oraninda klorheksidin glukonat içermektedir. 3 numarali kompozisyon agirlikça % 65-75 oraninda etil alkol ve agirlikça % 0,05-5 oraninda, tercihen agirlikça % 0,05- 0,1 oraninda benzetonyum klorür içermektedir. 4 numarali kompozisyon agirlikça % 65-75 oraninda etil alkol ve agirlikça % 0,01-1 oraninda, tercihen agirlikça % 0,05-0,2 oraninda didesil dimetil amonyum klorür içermektedir. 6 numarali kompozisyon agirlikça % 65-75 etil alkol ve agirlikça % 0,01-O,8 oraninda, , C16 % 3) içermektedir. dimetil amonyum klorür içermektedir. 8 numarali kompozisyon agirlikça % 65-75 etil alkol, agirlikça % 0,01-O,5 oraninda, didesildimetil amonyum klorür içermektedir. Hazirlanan kompozisyonlarin fiziksel özellikleri incelendiginde uygun ortam kosullari saglanmadiginda klorheksidin glukonat içeren kompozisyonun stabilitesinin ve dolayisiyla etkinliginin düstügü gözlemlenmistir. Cerrahi operasyona girmeden önce hastalarin cildine uygulandiginda cilt yapisini pozitif hale getirerek, ameliyat sorasinda olusabilecek enfeksiyon riskini azalttigi bilinen benzalkonyum klorürü içeren, özellikle karbonlu karbon zincirini, agirlikça % 3 oraninda 16 karbonlu karbon zincirini içeren benzalkonyum klorür bilesigini içeren kompozisyonlarin cilde tutunarak cildin dezenfekte edilmesini saglayan bir tabaka olusturduklari gözlemlenmistir. Benzalkonyum klorür bilesiklerinin, özellikle % 62-75 oraninda 12 karbonlu karbon zincirini, agirlikça % 21-30 oraninda 14 karbonlu karbon zincirini, agirlikça % 3 oraninda 16 karbonlu karbon zincirini içeren benzalkonyum klorür bilesiginin didesil dimetil amonyum klorür ile bir arada kullanilmasiyla elde edilen kompozisyonlarin ise hem alkolün buharlasmasinin ardindan da cilde tutunarak cildi dezenfekte ettikleri hem de etkinlik alanlarinin daha genis oldugu gözlemlenmistir. Farkli uzunlukta ve farkli miktarlarda karbon zinciri dagilimlarina sahip benzalkonyum klorür bilesiginin kullanimi Yapilan degerlendirmeler sonucunda agirlikça % 60-93 oraninda, tercihen agirlikça % 65- 75 oraninda en az bir tür alkol bilesigini, tercihen etil alkolü ve agirlikça % 0,01-5 oraninda, tercihen kuaterner amonyum yapili katyonik yüzey aktif maddeler arasindan seçilen en az bir tür katyonik yüzey aktif maddeyi içeren bulus konusu alkol bazli ürün gelistirilmistir. Alkolün buharlasmasindan sonra yüzey aktif maddenin cilt yüzeyinde kalmasi ile cildin bir süre daha patojenik mikroorganizmalardan korunmasi saglanmaktadir. Bulus konusu alkol bazli ürün tercih edilen bir uygulamasinda katyonik yüzey aktif madde oraninda 14 karbonlu karbon zincirini, agirlikça % 3 oraninda 16 karbonlu karbon zincirini içeren benzalkonyum klorürü agirlikça % 0,01-O,5 oraninda ve/veya didesil dimetil amonyum klorürü agirlikça % 0,0l-O,5 oraninda içermektedir. Bulusun alternatif bir uygulamasi benzalkonyum klorürü tercihen agirlikça % 0,04-0,06 oraninda ve didesildimetil amonyum klorürü tercihen agirlikça % 0,05-0,1 oraninda içermektedir. Bulus konusu alkol bazli ürün, alkolün buharlasmasinin ardindan da cildi dezenfekte etmeyi sürdürürken cilt florasina zarar vermemesi için en az bir tür prebiyotik içermektedir. Bulus konusu alkol bazli ürün tercihen agirlikça % 0,5-2 oraninda en az bir tür prebiyotik içermektedir. Bulusun konusu alkol bazli ürün tercihen ka rbohidrat oligosakkarit türü prebiyotikler, cilt florasini destekleyen galaktooligosakkarit türü prebiyotikler, mannan oligosakkarit türü prebiyotikler, fruktooligosakkarit türü prebiyotikler, inülin, alfa glukan oligosakkarit, ekstrakt türü prebiyotikler, tercihen igne yaprakli agaç ekstrakti, hindiba etanolik ekstrakti, yer elmasi ekstrakti, arasindan seçilen en az bir tür prebiyotik içermektedir. Bir tür fruktoz oligosakkarit olan inülin prebiyotik özelliginden dolayi son zamanlarda gida takviyelerinde siklikla kullanilmaktadir. Bifidobakteriler ve Laktobasiller gibi faydali mikroorganizmalar inülini fermente ederek kisa zincirli yag asitlerini ve laktati olusturmakta, böylece patojenik mikroorganizmalarin gelisimini sinirlayan asidik bir ortam meydana getirmektelerdir. Sindirim sistemindeki yararli mikroorganizmalarin (dogal probiyotiklerin) gelisimini tesvik ederek Escherichia coli ve Salmonella gibi patojenik mikroorganizmalarin kolonizasyonunu azaltan inülin sindirim sisteminde oldugu gibi cilt üzerinde de faydali mikroorganizmalarin gelismesini olumlu yönde etkilemesi sebebiyle tercih edilmektedir. Bulus konusu alkol bazli ürün tercih edilen bir uygulamasinda agirlikça % 65-75 etil alkol, ve/veya agirlikça % 0,01-0,5 oraninda didesil dimetil amonyum klorür yüzey aktif maddelerini ve prebiyotik olarak agirlikça % 0,5-1 oraninda inülin içermektedir. Bulus konusu alkol bazli ürün tercih edilen bir uygulamasinda agirlikça % 65-75 etil alkol, ve/veya agirlikça % 0,01-0,5 oraninda didesil dimetil amonyum klorür yüzey aktif maddelerini, prebiyotik olarak yer elmasi ekstrakti ve hindiba etanolik ekstraktini içeren karisimi agirlikça % 0,5-1 oraninda içermektedir. Bulus konusu alkol bazli ürün tercih edilen bir uygulamasinda agirlikça % 65-75 etil alkol, ve/veya agirlikça % 0,01-0,5 oraninda didesil dimetil amonyum klorür yüzey aktif maddelerini ve prebiyotik olarak agirlikça % 0,5-1 oraninda igne yaprakli agaç ekstraktini (Coniferous wood extract) içermektedir. Bulus konusu alkol bazli ürün tercih edilen bir uygulamasinda agirlikça % 65-75 etil alkol, ve/veya agirlikça % 0,01-0,5 oraninda didesil dimetil amonyum klorür yüzey aktif maddelerini ve prebiyotik olarak agirlikça % 0,5-1 oraninda alfa glukan oligosakkarit içermektedir. Bulus konusu alkol bazli ürün tercih edilen bir uygulamasinda agirlikça % 65-75 etil alkol, ve/veya agirlikça % 0,01-0,5 oraninda didesil dimetil amonyum klorür yüzey aktif maddelerini ve prebiyotik olarak agirlikça % 0,5-1 oraninda alfa glukan oligosakkarit ve/veya agirlikça % 0,5-1 oraninda inülin içermektedir. Bulus konusu alkol bazli ürünün yukarida açiklanan uygulamalarinin tümünün alkolün buharlasmasindan sonra yüzeye tutunma performanslari ve etki sürelerinin yani sira cilt florasinda bulunan faydali mikroorganizmalarin çogalmasinda ve aktivitelerinin artmasinda da etkili oldugu tespit edilmistir. Yüksek oranda alkol içeren ürünler mikroorganizmalarin etkisiz hale getirilmesinde etkilidirler ancak sik kullanilmalari, cildin en üst tabakasini olusturan ve temel görevi cildin su oranini % 10'un üzerinde tutarak dogal esnek ve elastik yapisini korumasini saglamak olan stratum corneumdaki dogal nemlendirici faktörlerin azalmasina, dolayisiyla su içeriginin de azalmasina, stratum corneumun islevini kaybetmesine ve cildin dogal yapisinin bozulmasina yol açmaktadir. Cildin nemli tutulmasi ve bahsedilen olumsuzluklarin yasanmamasi için bulus konusu alkol bazli ürün temel bilesenlere ilave olarak tercihen en az bir tür nemlendirici madde içermektedir. Bulus konusu ürün cildin nem dengesi bozulmadan, dolayisiyla tahris edilmeden dezenfekte edilmesini saglamak amaciyla tercihen agirlikça % 0,1-5 oraninda en az bir tür nemlendirici madde içermektedir. Nemlendirici maddeler, atmosferdeki nem orani cildin nem oranindan yüksek oldugunda dis ortamdan su çekerek, atmosferdeki nem orani cildin nem oranindan düsük oldugunda ise cildin epidermis tabakasindan su çekerek stratum corumuna nemlenmesini saglamaktalardir. Bulus konusu ürün tercihen gliserin, propilen glikol, pentilen glikol, kaprilil glikol gibi polihidrik alkoller, retinol (a vitamini), riboflavin (BZ vitamini), niyasinamid (B3 vitamini), pantenol (provitamin BS), biyotin, folik asit, tokoferil asetat (E vitamini) gibi vitaminler, sodyum Iaktat, üre, keratin, sodyum prolidin karboksilik asit (sodyum pca), hiyalüronik asit gibi ciltteki dogal nemlendirici faktörler, allantoin, Ianolin, sodyum hyaluronat, PEG- 75 Ianolin, sodyum glukonat, zeytinyagi PEG-7 esteri gibi bilesikler, bisabolol, aloe vera ekstra kti, stevia rebaudiana ekstrakti, cocos nucifera meyve ekstrakti, papatya ekstrakti gibi ekstraktlar, fruktoz, maltoz, glukoz, sorbitol, maltodekstrin, trehaloz, Iaktoz gibi sekerler, kolajen, keratin, çözünür bugday proteini (tritisol), hidrolize bugday proteini (vegepro), süt proteini (kazein), elastin gibi onarici proteinler, protein hidrolizatlari, arjinin, aspartik asit, glisin, lizin, alanin, serin, valin, prolin, hidroksi prolin, treonin, izolösin, histidin, fenilalanin gibi cildin dogal yapisinda bulunan iyilestirici amino asitler, etilheksil palmitat, izopropil miristat, izopropil palmitat, gliseril kaprilat gibi cilt yumusaticilari, dimetikon gibi silikonlar, jojoba yagi, badem yagi, avakado yagi, kako çekirdegi yagi, shea agaci yagi gibi bitkisel yaglar, vazelin, skualen, parafin, mineral yag gibi hidrokarbon yaglar, yag asitleri, yag alkolleri, esterler, peptitler, bitkisel mumlar, fosfolipidler, steroller arasindan seçilen en az bir tür nemlendirici madde içermektedir. Bulus konusu alkol bazli ürün tercih edilen bir uygulamasinda nemlendirici madde olarak agirlikça % 0,1-5 oraninda, tercihen agirlikça % 0,5 veya % 1 veya % 1,5 veya % 5 oraninda gliserin içermektedir. Bulus konusu alkol bazli ürün tercih edilen bir uygulamasinda nemlendirici madde olarak agirlikça % 0,1-1 oraninda, tercihen agirlikça % 0,2 veya % 0,5 veya %1 oraninda mineral yag içermektedir. Bulus konusu alkol bazli ürün tercih edilen bir uygulamasinda nemlendirici madde olarak agirlikça % 0,5-2 oraninda, tercihen agirlikça % 1 veya % 2 oraninda pantenol içermektedir. Bulus konusu alkol bazli ürün tercih edilen bir uygulamasinda nemlendirici madde olarak agirlikça % 0,1-5 oraninda, tercihen agirlikça % 0,5 veya % 1 veya % 1,5 veya % 5 oraninda propilen glikol içermektedir. Bulus konusu alkol bazli ürün tercih edilen bir uygulamasinda nemlendirici madde olarak agirlikça % 0,1-1 oraninda, tercihen agirlikça % 0,5 veya % 1 oraninda bisabolol içermektedir. Bulus konusu alkol bazli ürün tercih edilen bir uygulamasinda nemlendirici madde olarak agirlikça % 0,1-1 oraninda, tercihen agirlikça % 0,1 veya % 0,5 oraninda aloe vera ekstraktini içermektedir. Bulus konusu alkol bazli ürün tercih edilen bir uygulamasinda nemlendirici madde olarak agirlikça % 0,1-1 oraninda, tercihen agirlikça % 0,1 veya % 0,5 oraninda sodyum Iaktat içermektedir. Bulus konusu alkol bazli ürün tercih edilen bir uygulamasinda nemlendirici madde olarak agirlikça % 0,1-1 oraninda, tercihen % 0,1 oraninda tokoferol (E vitamini) içermektedir. Bulus konusu alkol bazli ürün tercih edilen bir uygulamasinda nemlendirici maddeler olarak agirlikça % 0,5 oraninda gliserin ve agirlikça % 0,1 oraninda aloe vera ekstrakti içermektedir. Bulus konusu alkol bazli ürün tercih edilen bir uygulamasinda nemlendirici maddeler olarak agirlikça % 0,5 oraninda gliserin ve agirlikça % 0,1 oraninda tokoferol (E vitamini) içermektedir. Bulus konusu alkol bazli ürün tercih edilen bir uygulamasinda nemlendirici maddeler olarak agirlikça % 0,5 oraninda gliserin, agirlikça % 0,15 oraninda sodyum PCA ve agirlikça % 0,12 oraninda sodyum laktat içermektedir. Bulusu konusu alkol bazli ürün tercih edilen bir uygulamasinda; agirlikça % 60-93 oraninda etil alkol, tercihen agirlikça % 65-75 oraninda etil alkol, katyonik yüzey aktif madde olarak % 0,01-0,5 oraninda benzalkonyum klorür dimetil amonyum klorür, nemlendirici madde olarak agirlikça % 0,5 oraninda gliserin ve/veya agirlikça % 0,1 oraninda tokoferol (E vitamini), prebiyotik olarak agirlikça % 0,5-1 oraninda inülin içermektedir. Bulusu konusu alkol bazli ürün tercih edilen bir diger uygulamasinda; agirlikça % 60-93 oraninda etil alkol, tercihen agirlikça % 65-75 oraninda etil alkol, katyonik yüzey aktif madde olarak agirlikça % 0,01-0,5 oraninda benzalkonyum didesil dimetil amonyum klorür, nemlendirici madde olarak agirlikça % 0,5 oraninda gliserin ve/veya agirlikça prebiyotik olarak yer elmasi ekstrakti ve hindiba etanolik ekstraktini içeren karisimi agirlikça % 0,5-1 oraninda içermektedir. Bulusu konusu alkol bazli ürün tercih edilen bir diger uygulamasinda; agirlikça % 60-93 oraninda etil alkol, tercihen agirlikça % 65-75 oraninda etil alkol, katyonik yüzey aktif madde olarak agirlikça % 0,01-0,5 oraninda benzalkonyum didesil dimetil amonyum klorü r, nemlendirici madde olarak agirlikça % 0,5 oraninda gliserin ve/veya agirlikça % 0,1 oraninda tokoferol (E vitamini), prebiyotik olarak agirlikça % 0,5-l oraninda igne yaprakli agaç ekstraktini içermektedir. Bulusu konusu alkol bazli ürün tercih edilen bir diger uygulamasinda; o agirlikça % 60-93 oraninda etil alkol, tercihen agirlikça % 65-75 oraninda etil alkol, o katyonik yüzey aktif madde olarak agirlikça % 0,01-0,5 oraninda benzalkonyum didesil dimetil amonyum klorür, - nemlendirici madde olarak agirlikça % 0,5 oraninda gliserin ve/veya agirlikça % 0,1 oraninda tokoferol (E vitamini), o prebiyotik olarak agirlikça % 0,5-1 oraninda alfa glukan oligosakkarit içermektedir. Bulusu konusu alkol bazli ürün tercih edilen bir diger uygulamasinda; o agirlikça %60-93 oraninda etil alkol, tercihen agirlikça % 65-75 oraninda etil alkol, - katyonik yüzey aktif madde olarak agirlikça % 0,01-0,5 oraninda benzalkonyum didesil dimetil amonyum klorür, o nemlendirici madde olarak agirlikça % 0,5 oraninda gliserin ve/veya agirlikça % 0,1 oraninda tokoferol (E vitamini) - prebiyotik olarak agirlikça % 0,5-1 oraninda alfa glukan oligosakkarit ve/veya agirlikça % 0,5-0,1 oraninda inülin içermektedir. Bulusun bahsedilen alternatif uygulamalarinda benzalkonyum klorürün (C12 % 62-75, klorürün tercihen agirlikça % 0,05-0,1 oraninda kullanilmasi da mümkündür. Bulus konusu alkol bazli ürün tercihen bir el antiseptigidir. Bulus konusu alkol bazli ürün tercihen bir dezenfektandir. Bulus konusu alkol bazli ürün cilde uygulandiginda dezenfekte edici alkolün buharlasmasindan sonra belirli bir süre boyunca ciltte patojenik bakterilerin birikmesini engellerken cildin dogal florasinda bulunan yararli mikroorganizmalarin gelisimini ve aktivitesini seçici olarak arttirmakta, cilt florasi için ideal kosullari yaratmaktadir. Temel etkilerinin yani sira bulus konusu ürün nemlendirici maddeleri içermesi durumunda cildin tahris edilmeden dezenfekte edilmesini de saglamaktadir. TR TR TR TR DESCRIPTION AN ALCOHOL-BASED PRODUCT THAT DISINFECTS THE SKIN AND SUPPORTS THE SKIN FLORA Subject of the Invention The subject of the invention is an alcohol-based product that disinfects the skin by adhering to the skin surface and continuing its effect after the alcohol in its content evaporates and at the same time prevents skin irritation by supporting the skin flora Known State of the Art A large number of pathogenic microorganisms accumulate on the skin due to constant contact with the external environment. Some of the infections seen on the skin and in any part of the body occur when the said microorganisms spread to these parts of the body. Therefore, regular disinfection of the skin is a primary precaution to be taken especially to prevent infectious diseases. In travel conditions where water cannot be accessed or in other public areas, it is not possible to disinfect the skin by washing. In order to neutralize bacteria on the skin with disinfection, to provide ideal hygiene conditions and to protect skin health, antiseptics and disinfectants that are applied to the skin in a practical way and do not require rinsing and drying are needed. This need increases considerably especially during epidemic periods. Such disinfecting products neutralize microorganisms that accumulate on the skin, especially when touching surfaces in public areas, and prevent them from spreading to the skin, thus preventing transmission from person to person. Such disinfectants, which do not require rinsing and drying after being applied to the skin, provide ease of use for users and reduce water consumption. Currently, alcohol-based or non-alcohol-based antiseptics and disinfectants are used in gel, foam or liquid form to disinfect the skin. Alcohol-based antiseptics are preferred by users more because they provide faster and more effective disinfection when applied to the skin compared to non-alcohol-based antiseptics. However, since the alcohol evaporates quickly, this effect is short-lived and pathogenic microorganisms begin to accumulate on the skin again in a short time. This situation leads to the continuous use of disinfectants, and the continuous use of disinfectants leads to poisoning and the decrease of the natural moisturizing factors, beneficial microorganisms and water content in the skin, and the deterioration of the natural structure of the skin. The deterioration of the skin structure also reduces the production of lipids that have a moisturizing effect, and the skin's moisture needs cannot be met by lipids. Water loss dries the skin, and itching, peeling and cracks occur in the dry skin. Cracks create a suitable environment for pathogenic microorganisms that are desired to be removed to shelter, and microorganisms accumulate in these cracks, which are open wounds, and cause infection over time. For these reasons, disinfectants containing cationic surface active agents, which have been found to reduce the risk of skin infection after surgery when applied to the patient's skin before surgery, are needed in order to disinfect the skin after the evaporation of the main component, alcohol, and thus to limit the use of disinfectants. Cationic surfactants interact with the surface of the negatively charged microorganism cell, disrupt the integrity of the cell membrane and cause cell death by penetrating into the cell, thus preventing the accumulation of bacteria, mold, fungi and viruses on the skin after the evaporation of alcohol. However, when surfactants remain on the skin for a long time, the beneficial microorganisms that make up the skin flora along with the pathogenic microorganisms on the skin lose their activity, and the natural structure of the skin is disrupted. In this case, in order to disinfect the skin while preserving its natural flora, after the use of disinfectants, care products containing skin flora-supporting additives are applied to the skin as a second process. The use of more than one product is costly for users, and the application of more than one process is a waste of time. Therefore, a practical disinfection process cannot be performed. For this reason, there is a need for alcohol-based antiseptics and disinfectants containing surfactants that ensure disinfection while preserving the natural flora of the skin. In order to eliminate the aforementioned negativities that arise from the use of currently used short-term effective alcohol-based disinfectants and antiseptics, an alcohol-based product has been developed within the scope of the invention, which contains at least one prebiotic agent that is a food source for beneficial microorganisms found in the natural flora of the skin and thus selectively increases the development and activity of beneficial microorganisms and creates ideal conditions for the skin flora, in addition to surfactants that prevent the accumulation of pathogenic microorganisms on the skin by adhering to the skin for a certain period of time after the evaporation of alcohol. The developed product may also contain moisturizing agents that ensure the preservation of the moisture balance of the skin and thus disinfection without irritation. Thus, in order to disinfect the skin and support its natural flora, there is no need to apply more than one hygiene and care product to the skin in more than one step, and skin cleansing and care is done with a single product that offers practical use to users, does not cause loss of time, is easy to produce, low cost and easily accessible to all segments of society, and with a single step application. Purpose of the Invention The purpose of the invention is to develop an alcohol-based product that provides disinfection of the skin by adhering to the skin and continuing its effect after the evaporation of the alcohol in its content. Another purpose of the invention is to develop an alcohol-based product that supports the skin flora by selectively increasing the development and activity of beneficial microorganisms found in the natural flora of the skin and eliminating the risk of infection on the skin. Another purpose of the invention is to develop an alcohol-based product with a content suitable for use with moisturizing agents that moisturize the skin while disinfecting it, thus eliminating the risk of experiencing symptoms such as dryness, cracking and burning on the skin. Another purpose of the invention is to develop a hand antiseptic with the features specified in the previous purposes of the invention. Description of the Invention The subject of the invention is an alcohol-based product that provides disinfection of the skin by adhering to the skin surface and continuing its effect after the evaporation of the alcohol in its content, and at the same time prevents irritation of the skin by supporting the skin flora. The alcohol-based product in question basically contains at least one type of alcohol compound, at least one type of cationic surfactant that remains on the skin surface after the evaporation of the alcohol compound and shows a disinfecting effect, and at least one type of prebiotic that supports the skin flora by ensuring the proliferation of beneficial microorganisms found in the skin flora. In a preferred application, the product in question contains at least one type of moisturizing agent that maintains the moisture balance of the skin in addition to the basic components. The product in question contains at least one type of alcohol, preferably ethyl alcohol, selected from isopropyl alcohol and ethyl alcohol, which are known to provide fast and effective disinfection, at a rate of 60-93% by weight, preferably 65-75% by weight. In order to determine the surfactant to be used in obtaining the product in question, the compositions were prepared by adding at least one type of cationic surfactant selected from benzethonium chloride, benzalkonium chloride, dodecyltrimethyl ammonium chloride, dodecyl benzyldimethyl ammonium chloride, cocobenzyldimethyl ammonium chloride or didecyldimethyl ammonium chloride compounds, which are preferably chlorhexidine gluconate or quaternary ammonium compounds, in varying amounts, preferably 60-93% by weight, preferably 65-75% by weight to at least one type of alcohol, preferably ethyl alcohol. The skin adhesion performances and effect durations of the obtained compositions after the evaporation of the alcohol were evaluated. As a result of the evaluations, the surface active agent/substances with high adhesion performance to be used in obtaining the final product were determined. It is known that benzalkonium chloride, a quaternary ammonium structured cationic surfactant, highly disinfects many types of microorganisms found on the skin and inanimate surfaces. There are benzalkonium chloride compounds with different lengths and different ratios of carbon chain distributions. The disinfecting effect of compounds containing 14 and 16 carbon chains is greater. In other words, high amounts of 14 and 16 carbon benzalkonium chloride compounds are sufficient to achieve the targeted effect even when used in low amounts in terms of the lengths of the carbon chains they contain. The effectiveness of the compound containing a 14 carbon chain is also higher than the compound containing a 16 carbon chain. In other words, the disinfecting effect varies according to the chain length, the amount of a certain length of chain and the type of microorganism affected by a certain length of chain. For this reason, in the preparation of some compositions, benzalkonium chloride compounds containing 62-75% by weight of 12-carbon carbon chain, carbon chain by weight and benzalkonium chloride compounds containing 50% by weight of 12-carbon carbon chain, 30% by weight of 14-carbon carbon chain, chain by weight were used. The effects of didecyldimethyl ammonium chloride and benzalkonium chloride on pathogenic microorganisms vary according to the type of microorganism. In other words, while benzalkonium chloride is more effective on some microorganisms, didecyl dimethyl ammonium chloride is more effective on some microorganisms. Therefore, considering that the combined use of didecyldimethyl ammonium chloride and benzalkonium chloride would expand the area of activity of the final products, compositions containing the two surfactants at different rates were prepared. Composition number 1 contains 65-75% by weight ethyl alcohol and 0.05-5% by weight, preferably 1-2% by weight chlorhexidine gluconate. Composition number 2 contains 65-75% by weight ethyl alcohol and 0.05-5% by weight, preferably 0.4-0.6% chlorhexidine gluconate. Composition 3 contains 65-75% by weight ethyl alcohol and 0.05-5% by weight, preferably 0.05-0.1% by weight benzethonium chloride. Composition 4 contains 65-75% by weight ethyl alcohol and 0.01-1% by weight, preferably 0.05-0.2% by weight didecyl dimethyl ammonium chloride. Composition 6 contains 65-75% by weight ethyl alcohol and 0.01-0.8% by weight, C16 (3%). dimethyl ammonium chloride. Composition 8 contains 65-75% by weight ethyl alcohol, 0.01-0.5% by weight didecyldimethyl ammonium chloride. When the physical properties of the prepared compositions were examined, it was observed that the stability and therefore the effectiveness of the composition containing chlorhexidine gluconate decreased when the appropriate environmental conditions were not provided. It was observed that the compositions containing benzalkonium chloride, which is known to reduce the risk of infection that may occur after surgery by making the skin structure positive when applied to the skin of patients before undergoing a surgical operation, especially the benzalkonium chloride compound containing a carbon-carbon chain, a 16-carbon carbon chain at a rate of 3% by weight, adhered to the skin and formed a layer that provided disinfection of the skin. It has been observed that the compositions obtained by using benzalkonium chloride compounds, especially those containing 62-75% 12-carbon chain, 21-30% 14-carbon chain, and 3% 16-carbon chain by weight, together with didecyl dimethyl ammonium chloride, both adhere to the skin after the evaporation of the alcohol and disinfect the skin, and have a wider area of activity. Use of benzalkonium chloride compound with different lengths and different amounts of carbon chain distributions As a result of the evaluations made, the alcohol-based product in question has been developed, which contains at least one type of alcohol compound, preferably ethyl alcohol, at a rate of 60-93% by weight, preferably 65-75% by weight, and at least one type of cationic surfactant, preferably selected from quaternary ammonium structured cationic surfactants, at a rate of 0.01-5% by weight. The skin is protected from pathogenic microorganisms for a while longer by the surfactant remaining on the skin surface after the evaporation of the alcohol. In a preferred embodiment of the alcohol-based product of the invention, it contains cationic surfactant ratio of 14 carbon chain, 3% by weight of benzalkonium chloride containing 16 carbon chain and 0.01-0.5% by weight and/or didecyl dimethyl ammonium chloride at 0.01-0.5% by weight. An alternative embodiment of the invention contains benzalkonium chloride preferably at 0.04-0.06% by weight and didecyldimethyl ammonium chloride preferably at 0.05-0.1% by weight. The alcohol-based product of the invention contains at least one type of prebiotic in order not to harm the skin flora while continuing to disinfect the skin after the evaporation of the alcohol. The alcohol-based product of the invention preferably contains at least one type of prebiotic at 0.5-2% by weight. The alcohol-based product, which is the subject of the invention, preferably contains at least one type of prebiotic selected from carbohydrate oligosaccharide type prebiotics, galactooligosaccharide type prebiotics supporting skin flora, mannan oligosaccharide type prebiotics, fructooligosaccharide type prebiotics, inulin, alpha glucan oligosaccharide, extract type prebiotics, preferably coniferous tree extract, chicory ethanolic extract, Jerusalem artichoke extract. Inulin, a type of fructose oligosaccharide, has recently been frequently used in food supplements due to its prebiotic properties. Beneficial microorganisms such as Bifidobacteria and Lactobacilli ferment inulin to form short-chain fatty acids and lactate, thus creating an acidic environment that limits the development of pathogenic microorganisms. Inulin, which reduces the colonization of pathogenic microorganisms such as Escherichia coli and Salmonella by encouraging the development of beneficial microorganisms (natural probiotics) in the digestive system, is preferred because it positively affects the development of beneficial microorganisms on the skin as well as in the digestive system. The alcohol-based product in question contains 65-75% by weight ethyl alcohol, and/or 0.01-0.5% by weight didecyl dimethyl ammonium chloride surfactants and 0.5-1% by weight inulin as a prebiotic in a preferred application. In a preferred embodiment of the alcohol-based product of the invention, it contains 65-75% by weight ethyl alcohol, and/or 0.01-0.5% by weight didecyl dimethyl ammonium chloride surfactants, and a mixture containing Jerusalem artichoke extract and chicory ethanolic extract as prebiotics at a rate of 0.5-1% by weight. The alcohol-based product of the invention contains, in a preferred embodiment, 65-75% by weight ethyl alcohol, and/or 0.01-0.5% by weight didecyl dimethyl ammonium chloride surfactants and 0.5-1% by weight coniferous wood extract as a prebiotic. The alcohol-based product of the invention contains, in a preferred embodiment, 65-75% by weight ethyl alcohol, and/or 0.01-0.5% by weight didecyl dimethyl ammonium chloride surfactants and 0.5-1% by weight alpha glucan oligosaccharide as a prebiotic. The alcohol-based product in question contains, in a preferred application, 65-75% by weight ethyl alcohol and/or 0.01-0.5% by weight didecyl dimethyl ammonium chloride surfactants and 0.5-1% by weight alpha glucan oligosaccharide and/or 0.5-1% by weight inulin as prebiotics. It has been determined that all of the above-described applications of the alcohol-based product in question are effective in the surface adhesion performances and effect durations after the evaporation of alcohol, as well as in the proliferation and increase in the activities of beneficial microorganisms in the skin flora. Products containing high levels of alcohol are effective in neutralizing microorganisms, but their frequent use leads to a decrease in the natural moisturizing factors in the stratum corneum, which forms the uppermost layer of the skin and whose main function is to maintain the skin's natural flexible and elastic structure by keeping the water content above 10%, thus decreasing the water content, causing the stratum corneum to lose its function and disrupting the skin's natural structure. In order to keep the skin moist and prevent the aforementioned negativities, the alcohol-based product in question preferably contains at least one type of moisturizing agent in addition to the basic components. The product in question preferably contains at least one type of moisturizing agent in a ratio of 0.1-5% by weight in order to disinfect the skin without disrupting its moisture balance and therefore without irritation. Moisturizing agents provide moisture to the stratum corum by drawing water from the external environment when the humidity rate in the atmosphere is higher than the moisture rate of the skin, and by drawing water from the epidermis layer of the skin when the humidity rate in the atmosphere is lower than the moisture rate of the skin. The product in question preferably contains polyhydric alcohols such as glycerin, propylene glycol, pentylene glycol, caprylyl glycol, vitamins such as retinol (vitamin A), riboflavin (vitamin BZ), niacinamide (vitamin B3), panthenol (provitamin BS), biotin, folic acid, tocopheryl acetate (vitamin E), natural moisturizing factors in the skin such as sodium lactate, urea, keratin, sodium prolydine carboxylic acid (sodium pca), hyaluronic acid, compounds such as allantoin, lanolin, sodium hyaluronate, PEG-75 lanolin, sodium gluconate, olive oil PEG-7 ester, bisabolol, aloe vera extract, stevia rebaudiana extract, cocos nucifera fruit extract, extracts such as chamomile extract, fructose, maltose, glucose, sorbitol, maltodextrin, Sugars such as trehalose and lactose, collagen, keratin, soluble wheat protein (tritisol), hydrolyzed wheat protein (vegepro), milk protein (casein), repair proteins such as elastin, protein hydrolysates, healing amino acids found in the natural structure of the skin such as arginine, aspartic acid, glycine, lysine, alanine, serine, valine, proline, hydroxy proline, threonine, isoleucine, histidine, phenylalanine, skin softeners such as ethylhexyl palmitate, isopropyl myristate, isopropyl palmitate, glyceryl caprylate, silicones such as dimethicone, vegetable oils such as jojoba oil, almond oil, avocado oil, cocoa seed oil, shea tree oil, hydrocarbon oils such as vaseline, squalene, paraffin, mineral oil, fatty acids, fatty alcohols, esters, peptides, vegetable waxes, phospholipids, sterols. The alcohol-based product of the invention contains at least one type of moisturizing agent selected from esters, peptides, vegetable waxes, phospholipids, sterols. In a preferred embodiment, the alcohol-based product of the invention contains 0.1-5% by weight, preferably 0.5% or 1% or 1.5% or 5% by weight of glycerin as a moisturizing agent. In a preferred embodiment, the alcohol-based product of the invention contains 0.1-1% by weight, preferably 0.2% or 0.5% or 1% by weight of mineral oil as a moisturizing agent. In a preferred embodiment, the alcohol-based product of the invention contains 0.5-2% by weight, preferably 1% or 2% by weight of panthenol as a moisturizing agent. The alcohol-based product of the invention, in a preferred embodiment, contains 0.1-5% by weight, preferably 0.5% or 1% or 1.5% or 5% propylene glycol as a moisturizing agent. The alcohol-based product of the invention, in a preferred embodiment, contains 0.1-1% by weight, preferably 0.5% or 1% by weight, bisabolol as a moisturizing agent. The alcohol-based product of the invention, in a preferred embodiment, contains 0.1-1% by weight, preferably 0.1% or 0.5% by weight, aloe vera extract as a moisturizing agent. The alcohol-based product of the invention, in a preferred embodiment, contains 0.1-1% by weight, preferably 0.1% or 0.5% by weight, sodium lactate as a moisturizing agent. The alcohol-based product of the invention, in a preferred embodiment, contains 0.1-1% by weight, preferably 0.1% tocopherol (vitamin E) as a moisturizing agent. The alcohol-based product of the invention, in a preferred embodiment, contains 0.5% by weight glycerin and 0.1% by weight aloe vera extract as moisturizing agents. The alcohol-based product of the invention, in a preferred embodiment, contains 0.5% by weight glycerin and 0.1% by weight tocopherol (vitamin E) as moisturizing agents. The alcohol-based product of the invention, in a preferred embodiment, contains 0.5% by weight glycerin, 0.15% by weight sodium PCA and 0.12% by weight sodium lactate as moisturizing agents. The alcohol-based product of the invention, in a preferred embodiment; It contains 60-93% by weight ethyl alcohol, preferably 65-75% by weight ethyl alcohol, 0.01-0.5% benzalkonium chloride dimethyl ammonium chloride as cationic surfactant, 0.5% by weight glycerin and/or 0.1% by weight tocopherol (vitamin E) as moisturizing agent, and 0.5-1% by weight inulin as prebiotic. In another preferred application of the alcohol-based product of the invention; It contains 60-93% by weight ethyl alcohol, preferably 65-75% by weight ethyl alcohol, 0.01-0.5% by weight benzalkonium didecyl dimethyl ammonium chloride as cationic surfactant, 0.5% by weight glycerin as moisturizing agent and/or a mixture containing Jerusalem artichoke extract and chicory ethanolic extract as prebiotics at a rate of 0.5-1% by weight. In another preferred application of the alcohol-based product of the invention; It contains 60-93% by weight ethyl alcohol, preferably 65-75% by weight ethyl alcohol, 0.01-0.5% by weight benzalkonium didecyl dimethyl ammonium chloride as cationic surfactant, 0.5% by weight glycerin and/or 0.1% by weight tocopherol (vitamin E) as moisturizing agent, 0.5-1% by weight coniferous tree extract as prebiotic. In another preferred application of the alcohol-based product of the invention; o 60-93% by weight ethyl alcohol, preferably 65-75% by weight ethyl alcohol, o 0.01-0.5% by weight benzalkonium didecyl dimethyl ammonium chloride as cationic surfactant, - 0.5% by weight glycerin and/or 0.1% by weight tocopherol (vitamin E) as moisturizing agent, o 0.5-1% by weight alpha glucan oligosaccharide as prebiotic. In another preferred application of the alcohol-based product of the invention; o 60-93% by weight ethyl alcohol, preferably 65-75% by weight ethyl alcohol, - 0.01-0.5% by weight benzalkonium didecyl dimethyl ammonium chloride as cationic surfactant, o 0.5% by weight glycerin and/or 0.1% by weight tocopherol (vitamin E) as moisturizing agent, - 0.5-1% by weight alpha glucan oligosaccharide and/or 0.5-0.1% by weight inulin as prebiotic. In the alternative applications of the invention, it is also possible to use benzalkonium chloride (C12 62-75%, chloride preferably at a rate of 0.05-0.1% by weight. The alcohol-based product in question is preferably a hand antiseptic. The alcohol-based product in question is preferably a disinfectant. When the alcohol-based product in question is applied to the skin, it prevents the accumulation of pathogenic bacteria on the skin for a certain period of time after the evaporation of the disinfectant alcohol, while selectively increasing the development and activity of beneficial microorganisms in the natural flora of the skin, creating ideal conditions for the skin flora. In addition to its basic effects, the product in question also provides disinfection of the skin without irritation if it contains moisturizing agents.TR TR TR TR

Claims (1)

1.ISTEMLER Bulus, cildin dezenfekte edilmesini saglayan ve cilt florasini destekleyen alkol bazli bir ürün olup özelligi, - en az bir tür alkol, - en az bir tür katyonik yüzey aktif madde, - en az bir tür prebiyotik içermesi ile karakterize edilmektedir. Istem l'e göre alkol bazli bir ürün olup özelligi, agirlikça % 65-75 oraninda en az bir tür alkol içermesi ile karakterize edilmektedir. Istem 1'e göre alkol bazli bir ürün olup özelligi, alkol olarak etil alkol veya izopropil alkol arasindan seçilen en az birtür alkol, tercihen etil alkol içermesi ile karakterize edilmektedir. istem l'e göre alkol bazli bir ürün olup özelligi, agirlikça % 0,01-5 oraninda en az bir tür katyonik yüzey aktif madde içermesi ile karakterize edilmektedir. Istem 1'e göre alkol bazli bir ürün olup özelligi, katyonik yüzey aktif madde olarak tercihen benzetonyum klorür, benzalkonyum klorür, dodesiltrimetil amonyum klorür, dodesil benzildimetil amonyum klorür, kokobenzildimetil amonyum klorür, didesil dimetil amonyum klorür arasindan seçilen en az bir tür katyonik yüzey aktif madde içermesi ile karakterize edilmektedir. Istem 1'e göre alkol bazli bir ürün olup özelligi, katyonik yüzey aktif madde olarak agirlikça % 0,01-0,5 oraninda benzalkonyum klorür ve/veya agirlikça % 0,01-O,5 oraninda didesil dimetil amonyum klorürü içermesi ile karakterize edilmektedir. Istem 1'e göre alkol bazli bir ürün olup özelligi, katyonik yüzey aktif madde olarak oraninda didesildimetil amonyum klorür içermesi ile karakterize edilmektedir. istem 6'ya veya istem 7'ye göre alkol bazli bir ürün olup özelligi, bahsedilen benzalkonyum klorürün agirlikça % 62-75 oraninda 12 karbonlu karbon zincirini, agirlikça % 21-30 oraninda 14 karbonlu karbon zincirini, agirlikça % 3 oraninda 16 karbonlu karbon zincirini içermesi ile karakterize edilmektedir. Istem 1'e göre alkol bazli bir ürün olup özelligi, agirlikça % 0,5-2 oraninda en az bir tür prebiyotik içermesi ile karakterize edilmektedir. Istem 1'e göre alkol bazli bir ürün olup özelligi, tercihen karbohidrat oligosakkarit türü prebiyotikler, fruktooligosakkarit türü prebiyotikler, inülin, galaktooligosakkarit türü prebiyotikler, mannan oligosakkarit türü prebiyotikler, alfa glukan oligosa kkarit, ekstrakt türü prebiyotikler, igne yaprakli agaç ekstrakti, hindiba etanolik ekstrakti, yer elmasi ekstrakti arasindan seçilen en az bir tür prebiyotigi içermesi ile karakterize edilmektedir. Istem 1'e göre alkol bazli bir ürün olup özelligi, o alkol olarak agirlikça % 65-75 etil alkol, 0› katyonik yüzey aktif madde olarak agirlikça % 0,01-O,5 oraninda o prebiyotik olarak agirlikça % 0,5-1 oraninda inülin içermesi ile karakterize edilmektedir. istem 1'e göre alkol bazli bir ürün olup özelligi, o alkol olarak agirlikça % 65-75 etil alkol, o katyonik yüzey aktif madde olarak agirlikça % 0,01-0,5 oraninda - prebiyotik olarak yer elmasi ekstrakti ve hindiba etanolik ekstraktini içeren karisimi agirlikça % 0,5-1 oraninda içermesi ile karakterize edilmektedir. 13. istem 1'e göre alkol bazli bir ürün olup özelligi, alkol olarak agirlikça % 65-75 etil alkol, katyonik yüzey aktif madde olarak agirlikça % 0,01-0,5 oraninda prebiyotik olarak agirlikça % 0,5-1 oraninda igne yaprakli agaç ekstraktini içermesi ile karakterize edilmektedir. 14. Istem 1'e göre alkol bazli bir ürün olup özelligi, alkol olarak agirlikça % 65-75 etil alkol, katyonik yüzey aktif madde olarak agirlikça % 0,01-0,5 oraninda prebiyotik olarak agirlikça % 0,5-1 oraninda alfa glukan oligosakkarit içermesi ile karakterize edilmektedir. 15. Istem l'e göre alkol bazli bir ürün olup özelligi, alkol olarak agirlikça % 65-75 etil alkol, katyonik yüzey aktif madde olarak agirlikça % 0,01-0,5 oraninda prebiyotik olarak agirlikça % 0,5-1 oraninda alfa glukan oligosakkarit ve/veya agirlikça % 0,5-1 oraninda inülin içermesi ile karakterize edilmektedir. bahsedilen katyonik yüzey aktif maddenin tercihen agirlikça % 0,04-0,06 oraninda benzalkonyum klorür ve/veya agirlikça % 0,05-0,1 oraninda didesildimetil amonyum klorür olmasi ile karakterize edilmektedir. Istem 1'e göre alkol bazli bir ürün olup özelligi, en az bir tür nemlendirici madde içermesi ile karakterize edilmektedir. Istem 17'ye göre alkol bazli bir ürün olup özelligi, bahsedilen nemlendirici maddeyi agirlikça % 0,1-5 oraninda içermesi ile karakterize edilmektedir. Istem 17'ye göre alkol bazli bir ürün olup özelligi, bahsedilen nemlendiricinin gliserin, propilen glikol, pentilen glikol, kaprilil glikol gibi polihidrik alkoller, retinol (a vitamini), riboflavin (BZ vitamini), niyasinamid (B3 vitamini), pantenol (provitamin B5), biyotin, folik asit, tokoferil asetat (E vitamini) gibi vitaminler, sodyum laktat, üre, keratin, sodyum prolidin karboksilik asit (sodyum pca), hiyalüronik asit gibi ciltteki dogal nemlendirici faktörler, allantoin, lanolin, sodyum hyaluronat, PEG-75 Ianolin, sodyum glukonat, zeytinyagi PEG-7 esteri gibi bilesikler, bisabolol, aloe vera ekstrakti, stevia rebaudiana ekstrakti, cocos nucifera meyve ekstrakti, papatya ekstrakti gibi ekstraktlar, fruktoz, maltoz, glukoz, sorbitol, maltodekstrin, trehaloz, Iaktoz gibi sekerler, kolajen, keratin, çözünür bugday proteini (tritisol), hidrolize bugday proteini (vegepro), süt proteini (kazein), elastin gibi onarici proteinler ya da protein hidrolizatlari, arjinin, aspartik asit, glisin, lizin, alanin, serin, valin, prolin, hidroksi prolin treonin, izolösin, histidin, fenilalanin gibi cildin dogal yapisinda bulunan iyilestirici amino asitler, etilheksil palmitat, izopropil miristat, izopropil palmitat, gliseril kaprilat gibi cilt yumusaticilarini, dimetikon gibi silikonlar, jojoba yagi, badem yagi, avakado yagi, kakao çekirdegi yagi, shea agaci yagi gibi bitkisel yaglar, vazelin, skualen, parafin, mineral yag gibi hidrokarbon yaglar, yag asitleri, yag alkolleri, esterler, peptitler, bitkisel mumlar, fosfolipidler, steroller arasindan seçilen en az bir nemlendirici madde olmasi ile karakterize edilmektedir. Istem 17'ye göre alkol bazli bir ürün olup özelligi, nemlendirici madde olarak agirlikça % 0,1-5 oraninda gliserin içermesi ile karakterize edilmektedir. . Istem 17'ye göre alkol bazli bir ürün olup özelligi, nemlendirici madde olarak agirlikça % 0,5 veya agirlikça %1 veya agirlikça % 1,5 veya agirlikça % 5 oraninda gliserin içermesi ile karakterize edilmektedir. Istem 17'ye göre alkol bazli bir ürün olup özelligi, nemlendirici madde olarak agirlikça % 0,1-1 oraninda mineral yag içermesi ile karakterize edilmektedir. Istem 17'ye göre alkol bazli bir ürün olup özelligi, nemlendirici madde olarak agirlikça % 0,2 veya agirlikça % 0,5 veya agirlikça %1 oraninda mineral yag içermesi ile karakterize edilmektedir. Istem 17'ye göre alkol bazli bir ürün olup özelligi, nemlendirici madde olarak agirlikça % 0,5-2 oraninda pantenol içermesi ile karakterize edilmektedir. istem 17'ye göre alkol bazli bir ürün olup özelligi, nemlendirici madde olarak agirlikça % 1 veya agirlikça % 2 oraninda pantenol içermesi ile karakterize edilmektedir. Istem 17'ye göre alkol bazli bir ürün olup özelligi, nemlendirici madde olarak agirlikça % 0,1-5 oraninda propilen glikol içermesi ile karakterize edilmektedir. Istem 17'ye göre alkol bazli bir ürün olup özelligi, nemlendirici madde olarak agirlikça % 0,5 veya % 1 veya % 1,5 veya % 5 oraninda propilen glikol içermesi ile karakterize edilmektedir. Istem 17'ye göre alkol bazli bir ürün olup özelligi, nemlendirici madde olarak agirlikça % 0,1-1 oraninda bisabolol içermesi ile karakterize edilmektedir. Istem 17'ye göre alkol bazli bir ürün olup özelligi, nemlendirici madde olarak agirlikça % 0,5 veya % 1 oraninda bisabolol içermesi ile karakterize edilmektedir. Istem 17'ye göre alkol bazli bir ürün olup özelligi, nemlendirici madde olarak agirlikça % 0,1-1 oraninda aloe vera ekstraktini içermesi ile karakterize edilmektedir. istem 17'ye göre alkol bazli bir ürün olup özelligi, nemlendirici madde olarak agirlikça % 0,1 veya % 0,5 oraninda aloe vera ekstraktini içermesi ile karakterize edilmektedir. Istem 17'ye göre alkol bazli bir ürün olup özelligi, nemlendirici madde olarak agirlikça % 0,1-1 oraninda sodyum laktat içermesi ile karakterize edilmektedir. Istem 17'ye göre alkol bazli bir ürün olup özelligi, nemlendirici madde olarak agirlikça % 0,1 veya % 0,5 oraninda sodyum laktat içermesi ile karakterize edilmektedir. Istem 17'ye göre alkol bazli bir ürün olup özelligi, nemlendirici madde olarak agirlikça % 0,1-1 oraninda tokoferol (E vitamini) içermesi ile karakterize edilmektedir. Istem 17'ye göre alkol bazli bir ürün olup özelligi, nemlendirici madde olarak agirlikça % 0,1 oraninda tokoferol (E vitamini) içermesi ile karakterize edilmektedir. Istem 17'ye göre alkol bazli bir ürün olup özelligi, nemlendirici madde olarak agirlikça % 0,5 oraninda gliserin ve/veya agirlikça % 0,1 oraninda aloe vera ekstrakti içermesi ile karakterize edilmektedir. Istem 17'ye göre alkol bazli bir ürün olup özelligi, nemlendirici madde olarak agirlikça % 0,5 oraninda gliserin ve/veya agirlikça % 0,1 oraninda tokoferol (E vitamini) içermesi ile karakterize edilmektedir. Istem 17'ye göre alkol bazli bir ürün olup özelligi, nemlendirici madde olarak agirlikça % 0,5 oraninda gliserin ve/veya agirlikça % 0,15 oraninda Sodyum PCA ve/veya agirlikça % 0,12 oraninda sodyum Iaktat içermesi ile karakterize edilmektedir. 39. Istem 17'ye göre alkol bazli bir ürün olup özelligi, alkol olarak agirlikça % 60-93 oraninda etil alkol, tercihen agirlikça % 65- 75 oraninda etil alkol, katyonik yüzey aktif madde olarak agirlikça % 0,01-0,5 oraninda agirlikça % 0,01-0,5 oraninda didesil dimetil amonyum klorür, nemlendirici madde olarak agirlikça % 0,5 oraninda gliserin ve/veya agirlikça % 0,1 oraninda tokoferol (E vitamini), prebiyotik olarak agirlikça % 0,5-1 oraninda inülin içermesi ile karakterize edilmektedir. 40. Istem 17'ye göre alkol bazli bir ürün olup özelligi, alkol olarak agirlikça % 60-93 oraninda etil alkol, tercihen agirlikça % 65- 75 oraninda etil alkol, katyonik yüzey aktif madde olarak agirlikça % 0,01-0,5 oraninda agirlikça % 0,01-0,5 oraninda didesil dimetil amonyum klorür, nemlendirici madde olarak agirlikça %0,5 oraninda gliserin ve/veya agirlikça % 0,1 oraninda tokoferol (E vitamini), prebiyotik olarak yer elmasi ekstrakti ve hindiba etanolikekstraktini içeren karisimi agirlikça % 0,5-1 oraninda içermesi ile karakterize edilmektedir. 41. Istem 17'ye göre alkol bazli bir ürün olup özelligi, alkol olarak agirlikça % 60-93 oraninda etil alkol, tercihen agirlikça % 65- 75 oraninda etil alkol, katyonik yüzey aktif madde olarak agirlikça % 0,01-0,5 oraninda agirlikça % 0,01-0,5 oraninda didesil dimetil amonyum klorür, nemlendirici madde olarak agirlikça % 0,5 oraninda gliserin ve/veya agirlikça % 0,1 oraninda tokoferol (E vitamini), o prebiyotik olarak agirlikça % 0,5-1 oraninda igne yaprakli agaç ekstraktini içermesi ile karakterize edilmektedir. 42. Istem 17'ye göre alkol bazli bir ürün olup özelligi; o alkol olarak agirlikça % 60-93 oraninda etil alkol, tercihen agirlikça % 65- 75 oraninda etil alkol, o katyonik yüzey aktif madde olarak agirlikça % 0,01-0,5 oraninda agirlikça % 0,01-0,5 oraninda didesildimetil amonyum klorür, o nemlendirici madde olarak agirlikça % 0,5 oraninda gliserin ve/veya agirlikça % 0,1 oraninda tokoferol (E vitamini), o prebiyotik olarak agirlikça % 0,5-1 oraninda alfa glukan oligosakkarit içermesi ile karakterize edilmektedir. 43. Istem 17'ye göre alkol bazli bir ürün olup özelligi; o alkol olarak agirlikça % 60-93 oraninda etil alkol, tercihen agirlikça % 65- 75 oraninda etil alkol, o katyonik yüzey aktif madde olarak agirlikça % 0,01-0,5 oraninda agirlikça % 0,01-O,5 oraninda didesildimetil amonyum klorür, o nemlendirici madde olarak agirlikça % 0,5 oraninda gliserin ve/veya agirlikça % 0,1 oraninda tokoferol (E vitamini), o prebiyotik olarak agirlikça % 0,5-1 oraninda alfa glukan oligosakkarit ve/veya agirlikça % 0,5-1 oraninda inülin içermesi ile karakterize edilmektedir. bahsedilen katyonik yüzey aktif maddenin tercihen agirlikça % 0,04-0,06 oraninda benzalkonyum klorür ve/veya agirlikça % 0,05-0,1 oraninda didesildimetil amonyum klorür olmasi ile karakterize edilmektedir. 45. Yukaridaki istemlerden herhangi birisine göre alkol bazli bir ürün olup özelligi, bir el antiseptigi olmasi ile karakterize edilmektedir. 46. Yukaridaki istemlerden herhangi birisine göre alkol bazli bir ürün olup özelligi, bir dezenfektan olmasi ile karakterize edilmektedir. TR TR TR TR1.CLAIMS The invention is an alcohol-based product that disinfects the skin and supports the skin flora and is characterized by containing - at least one type of alcohol, - at least one type of cationic surfactant, - at least one type of prebiotic. It is an alcohol-based product according to claim 1 and is characterized by containing at least one type of alcohol at a rate of 65-75% by weight. It is an alcohol-based product according to claim 1 and is characterized by containing at least one type of alcohol selected from ethyl alcohol or isopropyl alcohol, preferably ethyl alcohol. It is an alcohol-based product according to claim 1 and is characterized by containing at least one type of cationic surfactant at a rate of 0.01-5% by weight. It is an alcohol-based product according to claim 1, and is characterized by containing at least one type of cationic surfactant preferably selected from benzethonium chloride, benzalkonium chloride, dodecyltrimethyl ammonium chloride, dodecyl benzyldimethyl ammonium chloride, cocobenzyldimethyl ammonium chloride, didecyl dimethyl ammonium chloride as cationic surfactant. It is an alcohol-based product according to claim 1, and is characterized by containing 0.01-0.5% by weight benzalkonium chloride and/or 0.01-0.5% by weight didecyl dimethyl ammonium chloride as cationic surfactant. It is an alcohol-based product according to claim 1, and is characterized by containing 0.01-0.5% by weight didecyl dimethyl ammonium chloride as cationic surfactant. It is an alcohol-based product according to claim 6 or claim 7 and is characterized in that said benzalkonium chloride contains 62-75% by weight of 12-carbon carbon chain, 21-30% by weight of 14-carbon carbon chain, 3% by weight of 16-carbon carbon chain. It is an alcohol-based product according to claim 1 and is characterized in that it contains at least one type of prebiotic at 0.5-2% by weight. It is an alcohol-based product according to claim 1 and is characterized by containing at least one type of prebiotic preferably selected from carbohydrate oligosaccharide type prebiotics, fructooligosaccharide type prebiotics, inulin, galactooligosaccharide type prebiotics, mannan oligosaccharide type prebiotics, alpha glucan oligosaccharide, extract type prebiotics, coniferous tree extract, chicory ethanolic extract, Jerusalem artichoke extract. It is an alcohol-based product according to claim 1 and is characterized by containing 65-75% by weight ethyl alcohol as alcohol, 0.01-0.5% by weight as 0› cationic surfactant and 0.5-1% by weight inulin as prebiotic. It is an alcohol-based product according to claim 1, and is characterized in that it contains 65-75% by weight ethyl alcohol as alcohol, 0.01-0.5% by weight cationic surfactant - a mixture containing Jerusalem artichoke extract and chicory ethanolic extract as prebiotics at a rate of 0.5-1% by weight. 13. It is an alcohol-based product according to claim 1, and is characterized in that it contains 65-75% by weight ethyl alcohol as alcohol, 0.01-0.5% by weight cationic surfactant and 0.5-1% by weight coniferous tree extract as prebiotics. 14. An alcohol-based product according to claim 1, characterized in that it contains 65-75% by weight ethyl alcohol as alcohol, 0.01-0.5% by weight as cationic surfactant, 0.5-1% by weight alpha glucan oligosaccharide as prebiotic. 15. An alcohol-based product according to claim 1, characterized in that it contains 65-75% by weight ethyl alcohol as alcohol, 0.01-0.5% by weight as cationic surfactant, 0.5-1% by weight alpha glucan oligosaccharide as prebiotic and/or 0.5-1% by weight inulin. It is characterized in that said cationic surfactant is preferably 0.04-0.06% by weight benzalkonium chloride and/or 0.05-0.1% by weight didecyldimethyl ammonium chloride. It is an alcohol-based product according to claim 1, and is characterized in that it contains at least one type of moisturizing agent. It is an alcohol-based product according to claim 17, and is characterized in that it contains said moisturizing agent in a ratio of 0.1-5% by weight. According to claim 17, it is an alcohol-based product and its feature is that the said moisturizer is composed of polyhydric alcohols such as glycerin, propylene glycol, pentylene glycol, caprylyl glycol, vitamins such as retinol (vitamin A), riboflavin (vitamin BZ), niacinamide (vitamin B3), panthenol (provitamin B5), biotin, folic acid, tocopheryl acetate (vitamin E), sodium lactate, urea, keratin, sodium prolydine carboxylic acid (sodium pca), natural moisturizing factors in the skin such as hyaluronic acid, allantoin, lanolin, sodium hyaluronate, PEG-75 Lanolin, sodium gluconate, compounds such as olive oil PEG-7 ester, bisabolol, aloe vera extract, stevia rebaudiana extract, cocos nucifera fruit extract, extracts such as chamomile extract, fructose, maltose, Sugars such as glucose, sorbitol, maltodextrin, trehalose, lactose, collagen, keratin, soluble wheat protein (tritisol), hydrolyzed wheat protein (vegepro), milk protein (casein), elastin, repair proteins or protein hydrolysates, amino acids found naturally in the skin such as arginine, aspartic acid, glycine, lysine, alanine, serine, valine, proline, hydroxy proline threonine, isoleucine, histidine, phenylalanine, skin softeners such as ethylhexyl palmitate, isopropyl myristate, isopropyl palmitate, glyceryl caprylate, silicones such as dimethicone, vegetable oils such as jojoba oil, almond oil, avocado oil, cocoa seed butter, shea tree oil, petrolatum, squalene, paraffin, hydrocarbons such as mineral oil. It is characterized by containing at least one moisturizing agent selected from oils, fatty acids, fatty alcohols, esters, peptides, vegetable waxes, phospholipids, sterols. It is an alcohol-based product according to claim 17 and is characterized by containing 0.1-5% by weight glycerin as a moisturizing agent. . It is an alcohol-based product according to claim 17 and is characterized by containing 0.5% by weight or 1% by weight or 1.5% by weight or 5% by weight glycerin as a moisturizing agent. It is an alcohol-based product according to claim 17 and is characterized by containing 0.1-1% by weight mineral oil as a moisturizing agent. An alcohol-based product according to claim 17, characterized in that it contains 0.2 wt.% or 0.5 wt.% or 1 wt.% mineral oil as a moisturizing agent. An alcohol-based product according to claim 17, characterized in that it contains 0.5-2 wt.% panthenol as a moisturizing agent. An alcohol-based product according to claim 17, characterized in that it contains 1 wt.% or 2 wt.% panthenol as a moisturizing agent. An alcohol-based product according to claim 17, characterized in that it contains 0.1-5 wt.% propylene glycol as a moisturizing agent. An alcohol-based product according to claim 17, characterized in that it contains 0.5% or 1% or 1.5% or 5% by weight propylene glycol as a moisturizing agent. An alcohol-based product according to claim 17, characterized in that it contains 0.1-1% by weight bisabolol as a moisturizing agent. An alcohol-based product according to claim 17, characterized in that it contains 0.5% or 1% by weight bisabolol as a moisturizing agent. An alcohol-based product according to claim 17, characterized in that it contains 0.1-1% by weight aloe vera extract as a moisturizing agent. An alcohol-based product according to claim 17, characterized in that it contains 0.1% or 0.5% by weight aloe vera extract as a moisturizing agent. It is an alcohol-based product according to claim 17, and is characterized in that it contains 0.1-1% by weight sodium lactate as a moisturizing agent. It is an alcohol-based product according to claim 17, and is characterized in that it contains 0.1 or 0.5% by weight sodium lactate as a moisturizing agent. It is an alcohol-based product according to claim 17, and is characterized in that it contains 0.1-1% by weight tocopherol (vitamin E) as a moisturizing agent. It is an alcohol-based product according to claim 17, and is characterized in that it contains 0.1% by weight tocopherol (vitamin E) as a moisturizing agent. An alcohol-based product according to claim 17, characterized in that it contains 0.5 wt.% glycerin and/or 0.1 wt.% aloe vera extract as moisturizing agent. An alcohol-based product according to claim 17, characterized in that it contains 0.5 wt.% glycerin and/or 0.1 wt.% tocopherol (vitamin E) as moisturizing agent. An alcohol-based product according to claim 17, characterized in that it contains 0.5 wt.% glycerin and/or 0.15 wt.% sodium PCA and/or 0.12 wt.% sodium lactate as moisturizing agent. 39. An alcohol-based product according to claim 17, characterized by containing 60-93% by weight of ethyl alcohol as alcohol, preferably 65-75% by weight of ethyl alcohol, 0.01-0.5% by weight of didecyl dimethyl ammonium chloride as cationic surfactant, 0.01-0.5% by weight of glycerin and/or 0.1% by weight of tocopherol (vitamin E) as moisturizer, and 0.5-1% by weight of inulin as prebiotic. 40. An alcohol-based product according to claim 17, characterized by containing 60-93% by weight of ethyl alcohol as alcohol, preferably 65-75% by weight of ethyl alcohol, 0.01-0.5% by weight of didecyl dimethyl ammonium chloride as cationic surfactant, 0.01-0.5% by weight of glycerin and/or 0.1% by weight of tocopherol (vitamin E) as moisturizing agent, 0.5-1% by weight of a mixture containing Jerusalem artichoke extract and chicory ethanolic extract as prebiotics. 41. An alcohol-based product according to claim 17, characterized in that it contains 60-93% by weight ethyl alcohol as alcohol, preferably 65-75% by weight ethyl alcohol, 0.01-0.5% by weight didecyl dimethyl ammonium chloride as cationic surfactant, 0.01-0.5% by weight glycerin and/or 0.1% by weight tocopherol (vitamin E) as moisturizing agent, and 0.5-1% by weight coniferous tree extract as prebiotic. 42. An alcohol-based product according to claim 17, characterized in that it contains; It is characterized by containing: o 60-93% by weight ethyl alcohol as alcohol, preferably 65-75% by weight ethyl alcohol, o 0.01-0.5% by weight didecyldimethyl ammonium chloride as cationic surfactant, o 0.5% by weight glycerin and/or 0.1% by weight tocopherol (vitamin E) as moisturizing agent, o 0.5-1% by weight alpha glucan oligosaccharide as prebiotic. 43. It is an alcohol-based product according to claim 17 and its feature is; It is characterized by: o containing 60-93% by weight ethyl alcohol as alcohol, preferably 65-75% by weight ethyl alcohol, o 0.01-0.5% by weight didecyldimethyl ammonium chloride as cationic surfactant, o 0.5% by weight glycerin and/or 0.1% by weight tocopherol (vitamin E) as moisturizing agent, o 0.5-1% by weight alpha glucan oligosaccharide and/or 0.5-1% by weight inulin as prebiotic. characterised in that said cationic surfactant is preferably 0.04-0.06% by weight benzalkonium chloride and/or 0.05-0.1% by weight didecyldimethyl ammonium chloride. 45. An alcohol-based product according to any of the above claims, characterised in that it is a hand antiseptic. 46. An alcohol-based product according to any of the above claims, characterised in that it is a disinfectant. TR TR TR TR
TR2020/19409A 2020-12-01 2020-12-01 AN ALCOHOL-BASED PRODUCT THAT DISINFECTS THE SKIN AND SUPPORTS THE SKIN FLORA TR202019409A1 (en)

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