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TR200201719T2 - Yeni sübstitüe pirazolo[4,3-e]diazepinler, bunları ihtiva eden farmasötik terkipler, bunların tıbbi ürünler olarak kullanımı. - Google Patents

Yeni sübstitüe pirazolo[4,3-e]diazepinler, bunları ihtiva eden farmasötik terkipler, bunların tıbbi ürünler olarak kullanımı.

Info

Publication number
TR200201719T2
TR200201719T2 TR2002/01719T TR200201719T TR200201719T2 TR 200201719 T2 TR200201719 T2 TR 200201719T2 TR 2002/01719 T TR2002/01719 T TR 2002/01719T TR 200201719 T TR200201719 T TR 200201719T TR 200201719 T2 TR200201719 T2 TR 200201719T2
Authority
TR
Turkey
Prior art keywords
diazepines
pharmaceutical compositions
compositions containing
pirazolo
medicinal products
Prior art date
Application number
TR2002/01719T
Other languages
English (en)
Inventor
Burnouf Catherine
Berecibar Amaya
Navet Michel
Original Assignee
Warner-Lambert Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner-Lambert Company filed Critical Warner-Lambert Company
Publication of TR200201719T2 publication Critical patent/TR200201719T2/tr

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/14—Antitussive agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/16—Central respiratory analeptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Diabetes (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Psychiatry (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Transplantation (AREA)

Abstract

FORMÜL (I) Bu bulus, genel formül (I) e sahip, yeni sübstitüe edilmis pirazolo [4,3-e]diazepinler, bunlari ihtiva eden farmasötik terkipler, bunlarin tibbi ürünler olarak kullanimi ve bunlari hazirlamaya yönelik yöntemlerle ilgilidir.
TR2002/01719T 2000-01-05 2000-12-27 Yeni sübstitüe pirazolo[4,3-e]diazepinler, bunları ihtiva eden farmasötik terkipler, bunların tıbbi ürünler olarak kullanımı. TR200201719T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0000095A FR2803299B1 (fr) 2000-01-05 2000-01-05 NOUVELLES PYRAZOLO [4,3-e] DIAZEPINES SUBSTITUEES, COMPOSITIONS PHARMACEUTIQUES LES CONTENANT, UTILISATION A TITRE DE MEDICAMENT ET PROCEDES POUR LEUR PREPARATION

Publications (1)

Publication Number Publication Date
TR200201719T2 true TR200201719T2 (tr) 2002-12-23

Family

ID=8845641

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2002/01719T TR200201719T2 (tr) 2000-01-05 2000-12-27 Yeni sübstitüe pirazolo[4,3-e]diazepinler, bunları ihtiva eden farmasötik terkipler, bunların tıbbi ürünler olarak kullanımı.

Country Status (42)

Country Link
EP (1) EP1248787B1 (tr)
JP (1) JP2003519233A (tr)
KR (1) KR20020063293A (tr)
CN (1) CN1420888A (tr)
AP (1) AP2002002572A0 (tr)
AR (1) AR032298A1 (tr)
AT (1) ATE278692T1 (tr)
AU (1) AU3367801A (tr)
BG (1) BG106893A (tr)
BR (1) BR0016926A (tr)
CA (1) CA2396315A1 (tr)
CO (1) CO5290255A1 (tr)
CR (1) CR6693A (tr)
CZ (1) CZ20022222A3 (tr)
DE (1) DE60014712T2 (tr)
DZ (1) DZ3103A1 (tr)
EA (1) EA005071B1 (tr)
EE (1) EE200200373A (tr)
ES (1) ES2226978T3 (tr)
FR (1) FR2803299B1 (tr)
GT (1) GT200100002A (tr)
HK (1) HK1050002A1 (tr)
HN (1) HN2001000002A (tr)
HR (1) HRP20020577A2 (tr)
HU (1) HUP0204213A2 (tr)
IL (1) IL150394A0 (tr)
IS (1) IS6437A (tr)
MA (1) MA26863A1 (tr)
MX (1) MXPA02006618A (tr)
NO (1) NO20023249L (tr)
NZ (1) NZ519520A (tr)
OA (1) OA12134A (tr)
PA (1) PA8509601A1 (tr)
PE (1) PE20011041A1 (tr)
PL (1) PL356668A1 (tr)
SK (1) SK9402002A3 (tr)
SV (1) SV2001000253A (tr)
TN (1) TNSN01001A1 (tr)
TR (1) TR200201719T2 (tr)
UY (1) UY26517A1 (tr)
WO (1) WO2001049689A2 (tr)
ZA (1) ZA200205287B (tr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1199074A1 (en) * 2000-09-15 2002-04-24 Warner-Lambert Company Pharmaceutical composition for preventing or treating a disease associated with an excess of il-12 production
EP1188438A1 (en) * 2000-09-15 2002-03-20 Warner-Lambert Company Pharmaceutical composition for preventing or treating a disease associated with an excess of Il-12 production
AR058071A1 (es) * 2005-10-03 2008-01-23 Astrazeneca Ab Derivados de dihidropirazolo (3,4-e)(1,4)diazepina. procesos de obtencion y composiciones farmaceuticas.
KR20160080799A (ko) 2014-12-30 2016-07-08 한국해양과학기술원 금 촉매를 이용한 α-피론 유도체 전합성 방법 및 이에 의해 합성되어 인간 암세포주에 세포독성을 가지는 α-피론 유도체
CN110088108B (zh) 2016-12-12 2024-06-14 联合疗法公司 取代的吡唑并氮杂䓬-4-酮类及其作为磷酸二酯酶抑制剂的用途
JP7008073B2 (ja) 2016-12-12 2022-01-25 ユニオン・セラピューティクス・アクティエセルスカブ 置換ピラゾロアゼピン－４－オンおよびそれらのホスホジエステラーゼ阻害剤としての使用
WO2018108231A1 (en) 2016-12-12 2018-06-21 Leo Pharma A/S Substituted pyrazoloazepin-8-ones and their use as phosphodiesterase inhibitors
TWI812739B (zh) * 2018-06-21 2023-08-21 景凱生物科技股份有限公司 Nadph氧化酶抑制劑、含其的醫藥組合物、及其應用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3764688A (en) * 1972-07-27 1973-10-09 Abbott Lab 4,6-DIHYDRO-1,3-DIMETHYL-8-PHENYL-4-PROPARGYL-PYRAZOLO {8 4,3-e{9 {0 DIAZEPIN-5 (1H) ONE IN TREATING INFLAMMATION

Also Published As

Publication number Publication date
HK1050002A1 (zh) 2003-06-06
MXPA02006618A (es) 2002-09-30
EP1248787B1 (en) 2004-10-06
KR20020063293A (ko) 2002-08-01
GT200100002A (es) 2002-01-18
ZA200205287B (en) 2003-07-02
WO2001049689A3 (en) 2001-12-20
CA2396315A1 (en) 2001-07-12
HRP20020577A2 (en) 2003-12-31
CZ20022222A3 (cs) 2003-05-14
EA200200610A1 (ru) 2002-12-26
CO5290255A1 (es) 2003-06-27
DE60014712T2 (de) 2006-02-02
AU3367801A (en) 2001-07-16
EE200200373A (et) 2003-10-15
EA005071B1 (ru) 2004-10-28
PA8509601A1 (es) 2002-07-30
JP2003519233A (ja) 2003-06-17
MA26863A1 (fr) 2004-12-20
UY26517A1 (es) 2001-03-16
HUP0204213A2 (hu) 2003-04-28
NO20023249D0 (no) 2002-07-04
CR6693A (es) 2004-04-27
NO20023249L (no) 2002-09-04
ES2226978T3 (es) 2005-04-01
WO2001049689A2 (en) 2001-07-12
NZ519520A (en) 2004-02-27
DZ3103A1 (fr) 2004-06-20
ATE278692T1 (de) 2004-10-15
PE20011041A1 (es) 2001-10-12
SV2001000253A (es) 2001-10-16
IS6437A (is) 2002-06-19
HN2001000002A (es) 2001-09-26
OA12134A (en) 2006-05-05
FR2803299B1 (fr) 2004-09-17
AR032298A1 (es) 2003-11-05
FR2803299A1 (fr) 2001-07-06
BR0016926A (pt) 2002-11-19
PL356668A1 (en) 2004-06-28
TNSN01001A1 (fr) 2005-11-10
EP1248787A2 (en) 2002-10-16
CN1420888A (zh) 2003-05-28
DE60014712D1 (de) 2004-11-11
BG106893A (en) 2003-04-30
SK9402002A3 (en) 2003-08-05
AP2002002572A0 (en) 2002-09-30
IL150394A0 (en) 2002-12-01

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