TNSN88111A1 - Procede de purification d'une proteine - Google Patents
Procede de purification d'une proteineInfo
- Publication number
- TNSN88111A1 TNSN88111A1 TNTNSN88111A TNSN88111A TNSN88111A1 TN SN88111 A1 TNSN88111 A1 TN SN88111A1 TN TNSN88111 A TNTNSN88111 A TN TNSN88111A TN SN88111 A TNSN88111 A TN SN88111A TN SN88111 A1 TNSN88111 A1 TN SN88111A1
- Authority
- TN
- Tunisia
- Prior art keywords
- purification process
- protein purification
- disclosed
- technique
- impurities
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 238000001742 protein purification Methods 0.000 title 1
- 239000012535 impurity Substances 0.000 abstract 2
- NWUYHJFMYQTDRP-UHFFFAOYSA-N 1,2-bis(ethenyl)benzene;1-ethenyl-2-ethylbenzene;styrene Chemical compound C=CC1=CC=CC=C1.CCC1=CC=CC=C1C=C.C=CC1=CC=CC=C1C=C NWUYHJFMYQTDRP-UHFFFAOYSA-N 0.000 abstract 1
- 235000019750 Crude protein Nutrition 0.000 abstract 1
- 102000004457 Granulocyte-Macrophage Colony-Stimulating Factor Human genes 0.000 abstract 1
- 108010017213 Granulocyte-Macrophage Colony-Stimulating Factor Proteins 0.000 abstract 1
- 239000003729 cation exchange resin Substances 0.000 abstract 1
- 238000004255 ion exchange chromatography Methods 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 238000000746 purification Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/53—Colony-stimulating factor [CSF]
- C07K14/535—Granulocyte CSF; Granulocyte-macrophage CSF
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J39/00—Cation exchange; Use of material as cation exchangers; Treatment of material for improving the cation exchange properties
- B01J39/26—Cation exchangers for chromatographic processes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/18—Ion-exchange chromatography
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
- Enzymes And Modification Thereof (AREA)
- Ultra Sonic Daignosis Equipment (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
PROCEDE POUR SEPARER UNE PROTEINE BRUTE EN UNE FRACTION PROTEIQUE RELATIVEMENT PURE ET EN UNE FRACTION PROTEIQUE IMPURE CARACTERISEE PAR LA MISE EN CONTACT DE LA PROTEINE PURE AVEC UNE RESINE ECHANGEUSE D'IONS A UN PH TEL QUE LA PROTEINE PURE ET L'IMPURETE SONT CHARGEES DE FACON OPPOSEE, DE SORTE QUE L'UNE DESDITES FRACTIONS EST LIEE SELECTIVEMENT A LA RESINE ECHANGEUSE D'IONS
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11188687A | 1987-10-23 | 1987-10-23 |
Publications (1)
Publication Number | Publication Date |
---|---|
TNSN88111A1 true TNSN88111A1 (fr) | 1990-07-10 |
Family
ID=22340970
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TNTNSN88111A TNSN88111A1 (fr) | 1987-10-23 | 1988-10-20 | Procede de purification d'une proteine |
Country Status (21)
Country | Link |
---|---|
EP (2) | EP0391934A1 (fr) |
JP (1) | JPH0788395B2 (fr) |
KR (1) | KR930008447B1 (fr) |
CN (1) | CN1031943C (fr) |
AT (1) | ATE121418T1 (fr) |
AU (1) | AU626008B2 (fr) |
DE (1) | DE3853610T3 (fr) |
DK (1) | DK99690A (fr) |
ES (1) | ES2070855T5 (fr) |
FI (1) | FI103974B (fr) |
HU (1) | HU204537B (fr) |
IE (1) | IE72219B1 (fr) |
IL (1) | IL88118A (fr) |
MY (1) | MY108512A (fr) |
NO (1) | NO303451B1 (fr) |
NZ (1) | NZ226651A (fr) |
OA (1) | OA09787A (fr) |
PT (1) | PT88813B (fr) |
TN (1) | TNSN88111A1 (fr) |
WO (1) | WO1989003840A1 (fr) |
ZA (1) | ZA887862B (fr) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE68929566D1 (de) * | 1988-05-13 | 2010-01-28 | Amgen Inc | Verfahren zur Isolierung und Reinigung von G-CSF |
US7217689B1 (en) | 1989-10-13 | 2007-05-15 | Amgen Inc. | Glycosylation analogs of erythropoietin |
US5110913A (en) * | 1990-05-25 | 1992-05-05 | Miles Inc. | Antibody purification method |
US5463029A (en) * | 1992-11-23 | 1995-10-31 | Immunex Corporation | Purification of fusion proteins comprising GM-CSF and IL-3 |
EP0722329A4 (fr) * | 1993-09-15 | 1998-02-04 | Alpha Therapeutic Corp | Procede de purification d'une glycoproteine alpha 1?-acide et produit resultant |
US5808011A (en) * | 1996-07-01 | 1998-09-15 | Biopure Corporation | Method for chromatographic removal of prions |
US7304150B1 (en) | 1998-10-23 | 2007-12-04 | Amgen Inc. | Methods and compositions for the prevention and treatment of anemia |
PT1165119E (pt) | 1999-04-08 | 2004-02-27 | Genentech Inc | Composicao baseada em polipeptidos com cargas opostas |
EP2261230B1 (fr) * | 2002-09-11 | 2017-05-10 | Chugai Seiyaku Kabushiki Kaisha | Méthode de purification d'une protéine |
DE10360841A1 (de) * | 2003-12-20 | 2005-07-14 | Henkel Kgaa | Helle, stabile, staub- und geruchsarme Enzymgranulate |
US8067182B2 (en) * | 2005-03-11 | 2011-11-29 | Wyeth Llc | Method of weak partitioning chromatography |
SE529259C2 (sv) * | 2005-08-31 | 2007-06-12 | Ge Healthcare Bio Sciences Ab | Tillverkning av kromarografimatriser, en kromarografimatris, en vätskekromatografikolonn, prcess för att isolera målföreningar och användning av en kromarografimatris för vätskekromatografi |
AU2007317200B8 (en) * | 2006-11-10 | 2012-02-02 | Agriculture Victoria Services Pty Ltd. | Process for the preparation of angiogenin |
CN101556260B (zh) * | 2009-05-25 | 2012-01-11 | 北京理工大学 | 固定化pH梯度毛细管等电聚焦测定微生物等电点的方法 |
CN101556261B (zh) * | 2009-05-25 | 2012-01-11 | 北京理工大学 | 微管内等电聚焦和剪断吹出培养测定微生物等电点的方法 |
WO2013075740A1 (fr) * | 2011-11-23 | 2013-05-30 | Sanofi | Procédé de purification d'anticorps |
MX360453B (es) * | 2011-12-22 | 2018-11-01 | Genentech Inc | Cromatografia de membrana de intercambio ionico. |
DK2994485T3 (en) | 2013-05-06 | 2018-04-23 | Sanofi Sa | CONTINUOUS MULTIPLE STEP PROCEDURE FOR PURIFICATION OF ANTIBODIES |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4658018A (en) * | 1984-03-13 | 1987-04-14 | Immunex Corporation | Process for producing homogeneous colony stimulating factor |
IL76360A0 (en) * | 1984-09-26 | 1986-01-31 | Takeda Chemical Industries Ltd | Mutual separation of proteins |
ZA872781B (en) * | 1986-05-19 | 1987-10-05 | Immunology Ventures | B-cell stimulating factor |
-
1988
- 1988-10-19 EP EP88909648A patent/EP0391934A1/fr active Pending
- 1988-10-19 DE DE3853610T patent/DE3853610T3/de not_active Expired - Fee Related
- 1988-10-19 HU HU886264A patent/HU204537B/hu not_active IP Right Cessation
- 1988-10-19 AU AU26247/88A patent/AU626008B2/en not_active Ceased
- 1988-10-19 WO PCT/US1988/003589 patent/WO1989003840A1/fr active IP Right Grant
- 1988-10-19 KR KR1019890701131A patent/KR930008447B1/ko not_active IP Right Cessation
- 1988-10-19 ES ES88309824T patent/ES2070855T5/es not_active Expired - Lifetime
- 1988-10-19 JP JP63508950A patent/JPH0788395B2/ja not_active Expired - Lifetime
- 1988-10-19 EP EP88309824A patent/EP0313343B2/fr not_active Expired - Lifetime
- 1988-10-19 AT AT88309824T patent/ATE121418T1/de not_active IP Right Cessation
- 1988-10-20 PT PT88813A patent/PT88813B/pt not_active IP Right Cessation
- 1988-10-20 MY MYPI88001190A patent/MY108512A/en unknown
- 1988-10-20 NZ NZ226651A patent/NZ226651A/xx unknown
- 1988-10-20 ZA ZA887862A patent/ZA887862B/xx unknown
- 1988-10-20 TN TNTNSN88111A patent/TNSN88111A1/fr unknown
- 1988-10-20 IE IE316888A patent/IE72219B1/en not_active IP Right Cessation
- 1988-10-21 CN CN88107266A patent/CN1031943C/zh not_active Expired - Fee Related
- 1988-10-21 IL IL88118A patent/IL88118A/xx not_active IP Right Cessation
-
1990
- 1990-04-17 OA OA59777A patent/OA09787A/en unknown
- 1990-04-20 NO NO901769A patent/NO303451B1/no not_active IP Right Cessation
- 1990-04-23 DK DK099690A patent/DK99690A/da unknown
- 1990-04-23 FI FI902017A patent/FI103974B/fi not_active IP Right Cessation
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