SU663385A1 - Method of determining concentration of blood formative elements in liquids - Google Patents

Method of determining concentration of blood formative elements in liquids

Info

Publication number: SU663385A1
Authority: SU; USSR - Soviet Union
Prior art keywords: liquids; blood; determining concentration; formative elements; concentration
Prior art date: 1978-03-09

Application number

SU782583352A

Other languages

Russian (ru)

Inventor

Сергей Васильевич Гаташ

Капитон Михайлович Лакин

Олег Тимофеевич Николов

Юрий Федорович Крылов

Лидия Николаевна Лебидь

Владимир Александрович Макаров

Original Assignee

Московский Ордена Трудового Красного Знамени Медицинский Стоматологический Институт Им.Н.А.Семашко

Харьковский Ордена Трудового Красного Знамени Государственный Университет Им. А.М.Горького

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1978-03-09

Filing date

1978-03-09

Publication date

1979-05-25

1978-03-09 Application filed by Московский Ордена Трудового Красного Знамени Медицинский Стоматологический Институт Им.Н.А.Семашко, Харьковский Ордена Трудового Красного Знамени Государственный Университет Им. А.М.Горького filed Critical Московский Ордена Трудового Красного Знамени Медицинский Стоматологический Институт Им.Н.А.Семашко

1978-03-09 Priority to SU782583352A priority Critical patent/SU663385A1/en

1979-05-25 Application granted granted Critical

1979-05-25 Publication of SU663385A1 publication Critical patent/SU663385A1/en

Landscapes

Investigating Or Analysing Biological Materials (AREA)

Description

. Изобретение относитс к области медицины , а именно к способу количественного анализа крови, и может найти применение в диагностике тромбозов, кровотечений, лучевой болезни, некоторых гематологических и онкологических заболеваний. Известен способ определени концентрации форменных элементов крови в жидких средах ij ./ Н Однако известньй способ не обеспечи вает высокой точности. Целью изобретени вл етс повышение точности способа. Это достигаетс тем, что в дкой среде определ ют соотношение свободной и св занной воды и по величине этого соо гкошени определ ют концентрацию форменных э 1емен1ов крови. Величина соотношени свободной и св занной воды пропощйональна.числу клетсж в единице объема жидкости и не зависит от ее состава и распределени клеток в пбьеме. Соотношение свободной и св занной воды определ етс как отношение концентрации свободной воды (C|,gQe. ), к концентрации св занной воды (С.„, ), но может характеризоватьс и величинами относи тельных концентрацией CfgQg или С , так как С. + . .------ Относительную концентрацию свободной .Иди св занной воды монаю определить путем измерени времени продольной (Tjj ) или поперечной (Тд ) релаксации протонов Воды известными методами ЯМР - спектроскопии, ис:пользу выражение i рСВОБ 1 СВ91 1 г Tjf - измер емые величины параметров Т, или Т ; -. ТТ Т| - временна продольной или поперечной релаксации соответственно прот ипв свободней и св заннпй впды.. . The invention relates to the field of medicine, namely to a method for quantitative analysis of blood, and may find application in the diagnosis of thrombosis, bleeding, radiation sickness, some hematological and oncological diseases. The known method of determining the concentration of blood corpuscles in liquid media ij ./ H However, limestone does not provide high accuracy. The aim of the invention is to improve the accuracy of the method. This is achieved by determining the ratio of free and bound water in such a medium and determining the concentration of blood forms of blood by the magnitude of this ratio. The value of the ratio of free and bound water is pro-squashed to the number of cells in a unit volume of liquid and does not depend on its composition or distribution of cells in the cell. The ratio of free and bound water is defined as the ratio of the concentration of free water (C |, gQe.) To the concentration of bound water (C.n.,), but it can also be characterized by relative values of CfgQg or C, since C. + . .------ The relative concentration of free water. If monitored water is determined by measuring the time of longitudinal (Tjj) or transverse (Td) relaxation of protons of Water using known methods of NMR spectroscopy, using: measured values of parameters T, or T; -. TT TT | - temporary longitudinal or transverse relaxation, respectively, prow ipv freer and related vpda ..

SU782583352A 1978-03-09 1978-03-09 Method of determining concentration of blood formative elements in liquids SU663385A1 (en)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
SU782583352A SU663385A1 (en)	1978-03-09	1978-03-09	Method of determining concentration of blood formative elements in liquids

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
SU782583352A SU663385A1 (en)	1978-03-09	1978-03-09	Method of determining concentration of blood formative elements in liquids

Publications (1)

Publication Number	Publication Date
SU663385A1 true SU663385A1 (en)	1979-05-25

Family

ID=20750511

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SU782583352A SU663385A1 (en)	1978-03-09	1978-03-09	Method of determining concentration of blood formative elements in liquids

Country Status (1)

Country	Link
SU (1)	SU663385A1 (en)

1978
- 1978-03-09 SU SU782583352A patent/SU663385A1/en active

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