SU505364A3 - Способ получени производных 4н-бензо (4,5)ц клогепта (1,2-в) триофена - Google Patents

Способ получени производных 4н-бензо (4,5)ц клогепта (1,2-в) триофена

Info

Publication number: SU505364A3
Authority: SU; USSR - Soviet Union
Prior art keywords: benzo; triofen; clogpeta; obtaining derivatives; derivatives
Prior art date: 1972-01-24

Application number

SU2027852A

Other languages

English (en)

Inventor

Буркин Жан-Пьер

Шварб Густав

Вальдфогель Эрвин

Original Assignee

Сандос Аг (Фирма)

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1972-01-24

Filing date

1974-05-28

Publication date

1976-02-28

1974-05-28 Application filed by Сандос Аг (Фирма) filed Critical Сандос Аг (Фирма)

1976-02-28 Application granted granted Critical

1976-02-28 Publication of SU505364A3 publication Critical patent/SU505364A3/ru

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/08—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing alicyclic rings

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Epidemiology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Plural Heterocyclic Compounds (AREA)

Description

(54) СПОСОБ ПОЛУЧЕНИЯ ПРОИЗВОДНЫХ 4Н-БЕНЗО(4,5)ЦИКЛОГЕПТА(1,2-Ь)ТИОФЕНА

Изобретение относитс IK способу получени неописанных в литературе производных 4Нбензо (4,5)циклогептан(1,2 -Ь)тиофена общей формулы

ТОН

или их солей,

где RI - водород или наход щийс в положении 6 или 7 галоид, в частности хлор или брам или низший алкоксиостато,к;

R2- низший алкил или бензильна или дифенилметильна группа, причем фи ильные группы могут содержать галоген, в частности хлор, фтор или бром;

если RI - низша алкоксигруппа и/или RS - низша аЛКильна групла, то они, в частности, содержат 1-4 атома }тлерода;

гидроксииминогруппа находитс в положении 9 или 10.

Известен способ получени соединени общей формулы:

где RI - водород или наход щийс в положении 6 или 7 галоид, или низший алкоксильный остаток;

R2 - низщий алкил,

путем гидролиза и дигидратации соединени формулы:

SU2027852A 1972-01-24 1974-05-28 Способ получени производных 4н-бензо (4,5)ц клогепта (1,2-в) триофена SU505364A3 (ru)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
CH98872A CH565172A5 (en)	1972-01-24	1972-01-24	4-piperidylidene benzocycloheptathiophenes - - antihistamines and serotonin and acetyl choline inhibitors

Publications (1)

Publication Number	Publication Date
SU505364A3 true SU505364A3 (ru)	1976-02-28

Family

ID=4199855

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SU2027852A SU505364A3 (ru)	1972-01-24	1974-05-28	Способ получени производных 4н-бензо (4,5)ц клогепта (1,2-в) триофена

Country Status (6)

Country	Link
CH (1)	CH565172A5 (ru)
CS (1)	CS180000B2 (ru)
DK (1)	DK134405B (ru)
ES (1)	ES438596A1 (ru)
PL (1)	PL92124B1 (ru)
SU (1)	SU505364A3 (ru)

1972
- 1972-01-24 CH CH98872A patent/CH565172A5/de not_active IP Right Cessation
1973
- 1973-01-15 DK DK22573A patent/DK134405B/da not_active IP Right Cessation
- 1973-01-22 PL PL18205073A patent/PL92124B1/pl unknown
- 1973-01-23 CS CS415273A patent/CS180000B2/cs unknown
1974
- 1974-05-28 SU SU2027852A patent/SU505364A3/ru active
1975
- 1975-06-16 ES ES438596A patent/ES438596A1/es not_active Expired

Also Published As

Publication number	Publication date
CS180000B2 (en)	1977-12-30
CH565172A5 (en)	1975-08-15
DK134405C (ru)	1977-03-28
PL92124B1 (ru)	1977-03-31
DK134405B (da)	1976-11-01
ES438596A1 (es)	1977-09-01

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