SU368274A1 - METHOD OF OBTAINING N-FOCFORIL-N'-p- (FOSFOHIL) - ETHYLTIOMETRY - Google Patents

Description

one

The invention relates to a method for producing organophosphorus compounds not described in the literature with the general formula

OR

/

RP

OCH, CH, NHCNH - P (OR),

II Oh

Iiii

So

where R is alkyl, aryl, aralkyl;

R is alkyl or aryloxyalkyl; R is alkyl,

which can be used as pesticides, plasticizers, extractants, etc.

The proposed method consists in the interaction of acidic ethers of phosphonic acids with dialkylphosphoric acid isothiocyanates and ethylenemip. The reaction proceeds according to the scheme:

sn.

OR

./

g /

RP + (), PNCS + HN :: I II OHII CH,

oo

-OR

RP

- 11 OCH.CH, NHCNHOII

S

2

where R, R and R are as defined above.

It is better to conduct the reaction at 20–50 ° C and mix equimolecular amounts of the initial reagents in an organic solvent medium, for example, benzene. As a result of the reaction, no by-products are formed and the desired products are isolated by known methods practically with quantitative yield. They are sedentary liquids or paraffin masses. The degree of purity and structure are confirmed by elemental analysis and paper chromatography.

Example. Getting N-dibutoxyphosphoryl-N-p - (O-2 - phenoxyethylmethylphosphonyl) ethylthiourea.

To a solution of 0.015 gmol of 0-2-phenoxyethylmethylphosphonic acid in 20 ml of dry benzene at 20 ° C and stirring was added a solution of 0.015 gmol of dibutylphosphoric isothiocyanate to 5 ml of benzene, stirred for 1 hour at room temperature

2 hours at 50 ° C, cooled to 20 ° C and a solution of 0.015 g-mol ethylenimI1Ha in

3 ml of benzene (cooling with ice water). After addition of ethyleneimine, it is stirred for 1 hour at room temperature and 2 hours at 40-45 ° C, the solvent is distilled off in a vacuum created by a water-jet pump, and

3

I get a white sedentary liquid. The output is quantitative, p 1.5100.

Found,%: N 5.31; R 11.97; S 6.43.

SaoNzbMgOTRgZ.

one

Calculated,%: N 5.5; P 12.20; S 6.30. The compounds listed in the table are likewise obtained.

Subject invention

Claims (2)

1. Method for preparing N-phosphoryl-M-p- (phosphonyl) -ethylthiourea, characterized in that the acidic esters of phosphonic acids are treated with dialkyl phosphoric acid isothiocyanates and ethyleneimine, followed by isolation of the target product by known methods. 2. A method according to claim 1, characterized in that the process is conducted in an environment of an organic solvent, for example benzene, at 20-50 ° C.