SU199139A1 - METHOD OF OBTAINING 2,6-DICHLOR-4-KUMYLPHENOL - Google Patents
METHOD OF OBTAINING 2,6-DICHLOR-4-KUMYLPHENOLInfo
- Publication number
- SU199139A1 SU199139A1 SU1089038A SU1089038A SU199139A1 SU 199139 A1 SU199139 A1 SU 199139A1 SU 1089038 A SU1089038 A SU 1089038A SU 1089038 A SU1089038 A SU 1089038A SU 199139 A1 SU199139 A1 SU 199139A1
- Authority
- SU
- USSR - Soviet Union
- Prior art keywords
- kumylphenol
- dichlor
- obtaining
- cumylphenol
- chlorine
- Prior art date
Links
- 229910052801 chlorine Inorganic materials 0.000 description 3
- 239000000460 chlorine Substances 0.000 description 3
- ZAMOUSCENKQFHK-UHFFFAOYSA-N chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 description 3
- CJWNFAKWHDOUKL-UHFFFAOYSA-N 2-(2-phenylpropan-2-yl)phenol Chemical compound C=1C=CC=C(O)C=1C(C)(C)C1=CC=CC=C1 CJWNFAKWHDOUKL-UHFFFAOYSA-N 0.000 description 2
- TVMXDCGIABBOFY-UHFFFAOYSA-N Octane Chemical compound CCCCCCCC TVMXDCGIABBOFY-UHFFFAOYSA-N 0.000 description 2
- UHOVQNZJYSORNB-UHFFFAOYSA-N benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 description 2
- RTZKZFJDLAIYFH-UHFFFAOYSA-N diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- -1 2,6-dichloro-4-cumylphenol Chemical compound 0.000 description 1
- AZWABZDQHDYHGK-UHFFFAOYSA-N 2-chloro-4-(2-phenylpropan-2-yl)phenol Chemical compound C=1C=C(O)C(Cl)=CC=1C(C)(C)C1=CC=CC=C1 AZWABZDQHDYHGK-UHFFFAOYSA-N 0.000 description 1
- 229940088623 Biologically Active Substance Drugs 0.000 description 1
- 101700076723 NOC2L Proteins 0.000 description 1
- KZBUYRJDOAKODT-UHFFFAOYSA-N chlorine Chemical compound ClCl KZBUYRJDOAKODT-UHFFFAOYSA-N 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 238000004821 distillation Methods 0.000 description 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000001953 recrystallisation Methods 0.000 description 1
Description
Предлагаемый способ получени 2,6-дил хлор-4-кумилфенола состоит в том, что кумилфенол в расплавленном виде подвергают взаимодействию с газообразным хлором при 50-73°С.The proposed method for the preparation of 2,6-dil chloro-4-cumylphenol is that cumylphenol in molten form is reacted with chlorine gas at 50-73 ° C.
Полученное соединение можно примен ть как биологически активное вепдество.The resulting compound can be used as a biologically active substance.
Пример. В трехгорлую колбу с мешалкой , термометром и трубкой дл подвода хлора , помещают 30 г (0,14 моль) кумилфенола и расплавл ют его на вод ной бапе (т. пл. ). Затем пропускают хлор со скоростью, позвол юш,ей выдерживать температуру реакционной массы между 50-73°С. После получени привеса в 9,6 г смесь разгон ют в вакууме в перегонной системе.Example. In a three-necked flask with a stirrer, a thermometer, and a chlorine supply tube, 30 g (0.14 mol) of cumylphenol are placed and melted on a water pad (mp.). Chlorine is then passed at a rate that allows it to withstand the temperature of the reaction mass between 50-73 ° C. After a gain of 9.6 g was obtained, the mixture was distilled under vacuum in a distillation system.
Выделено 32,5 г (82% вых.) 2,6-дихлор-4кумилфенола с т. кип. 203-204°С/10 мм.Про232.5 g (82% ov.) Of 2,6-dichloro-4 cumylphenol with m.p. 203-204 ° C / 10 mm. Pro2
дукт кристаллизуетс в виде кристаллов ромбической формы. После перекристаллизации из н-октана продукт представл ет собой белое кристаллическое вещество с т. пл. 59,5°С.Dukt crystallizes in the form of rhombic crystals. After recrystallization from n-octane, the product is a white crystalline substance with m.p. 59.5 ° C.
Найдено, %: С 63,98; 64,04; П 4,92; 5; С1 25,5.Found,%: C 63.98; 64.04; P 4.92; five; C1 25.5.
CisHiiOCl,.CisHiiOCl ,.
Вычислено, %: С 64,07; Н 5,02, С1 25,22.Calculated,%: C 64.07; H 5.02, C1 25.22.
Вещество хорошо раствор етс в спирте, эфире, бензоле; в воде практически пераство римо.The substance is highly soluble in alcohol, ether, benzene; in the water almost perastvo Rome.
Предмет изобретени Subject invention
Способ получени 2,6-дихлор-4-кумилфенола , отличающийс тем, что расплавленный ку милфенол подвергают взаимодействию с га зообразным хлором при 50-73°С.A process for the preparation of 2,6-dichloro-4-cumylphenol, characterized in that the molten cubic milfenol is reacted with gaseous chlorine at 50-73 ° C.
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SU199139A1 true SU199139A1 (en) |
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