[go: up one dir, main page]

SMT202000684T1 - Trattamento delle malattie neurologiche - Google Patents

Trattamento delle malattie neurologiche

Info

Publication number
SMT202000684T1
SMT202000684T1 SM20200684T SMT202000684T SMT202000684T1 SM T202000684 T1 SMT202000684 T1 SM T202000684T1 SM 20200684 T SM20200684 T SM 20200684T SM T202000684 T SMT202000684 T SM T202000684T SM T202000684 T1 SMT202000684 T1 SM T202000684T1
Authority
SM
San Marino
Prior art keywords
treatment
neurological diseases
neurological
diseases
Prior art date
Application number
SM20200684T
Other languages
English (en)
Inventor
Christian Hölscher
Original Assignee
Lancaster Univ Business Enterprises Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lancaster Univ Business Enterprises Limited filed Critical Lancaster Univ Business Enterprises Limited
Publication of SMT202000684T1 publication Critical patent/SMT202000684T1/it

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/26Glucagons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/542Carboxylic acids, e.g. a fatty acid or an amino acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/605Glucagons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Psychiatry (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Hospice & Palliative Care (AREA)
  • Epidemiology (AREA)
  • Psychology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Peptides Or Proteins (AREA)
SM20200684T 2016-12-05 2017-12-04 Trattamento delle malattie neurologiche SMT202000684T1 (it)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB1620611.2A GB201620611D0 (en) 2016-12-05 2016-12-05 Treatment of neurological diseases
EP17811693.5A EP3548061B1 (en) 2016-12-05 2017-12-04 Treatment of neurological diseases
PCT/GB2017/053655 WO2018104718A1 (en) 2016-12-05 2017-12-04 Treatment of neurological diseases

Publications (1)

Publication Number Publication Date
SMT202000684T1 true SMT202000684T1 (it) 2021-01-05

Family

ID=58159786

Family Applications (1)

Application Number Title Priority Date Filing Date
SM20200684T SMT202000684T1 (it) 2016-12-05 2017-12-04 Trattamento delle malattie neurologiche

Country Status (25)

Country Link
US (2) US11220534B2 (it)
EP (1) EP3548061B1 (it)
JP (1) JP7099729B2 (it)
KR (1) KR102600128B1 (it)
CN (1) CN110312520B (it)
AU (1) AU2017371811B2 (it)
BR (1) BR112019011462A2 (it)
CA (1) CA3044797A1 (it)
CL (1) CL2019001512A1 (it)
CO (1) CO2019006979A2 (it)
CY (1) CY1123623T1 (it)
DK (1) DK3548061T3 (it)
ES (1) ES2833408T3 (it)
GB (1) GB201620611D0 (it)
HR (1) HRP20201959T1 (it)
HU (1) HUE052766T2 (it)
LT (1) LT3548061T (it)
MX (1) MX2019006495A (it)
PT (1) PT3548061T (it)
RS (1) RS61230B1 (it)
RU (1) RU2755997C2 (it)
SI (1) SI3548061T1 (it)
SM (1) SMT202000684T1 (it)
WO (1) WO2018104718A1 (it)
ZA (1) ZA201903003B (it)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201620611D0 (en) * 2016-12-05 2017-01-18 Univ Of Lancaster Treatment of neurological diseases
TW202140058A (zh) * 2020-01-30 2021-11-01 美商美國禮來大藥廠 提派肽(tirzepatide)之治療用途
WO2022018186A1 (en) 2020-07-22 2022-01-27 Novo Nordisk A/S Co-agonists at glp-1 and gip receptors suitable for oral delivery
WO2022065897A1 (ko) * 2020-09-25 2022-03-31 한미약품 주식회사 글루카곤, glp-1 및 gip 수용체 모두에 활성을 갖는 삼중 활성체 또는 이의 결합체의 신경퇴행성 질환의 치료 용도
CN114617956B (zh) * 2020-12-10 2023-10-03 江苏中新医药有限公司 一种高效降糖的蛋白质药物
CN114042149B (zh) * 2021-12-03 2023-06-16 中国人民解放军空军军医大学 D-Ala2-GIP用于制备治疗焦虑症药物的应用
TW202330584A (zh) 2022-01-20 2023-08-01 丹麥商諾佛 儂迪克股份有限公司 前藥及其用途
WO2023151594A1 (en) * 2022-02-11 2023-08-17 Hangzhou Sciwind Biosciences Co., Ltd. A composition comprising gip receptor agonists and glp-1 receptor agonists and use thereof
WO2024209050A1 (en) 2023-04-05 2024-10-10 Antag Therapeutics Aps Gip activity modulators and orthostatic intolerance

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2913056A1 (en) * 2006-01-05 2015-09-02 The University of Utah Research Foundation Methods and compositions related to improving properties of pharmacological agents targeting nervous system
CN104945500B (zh) 2008-06-17 2019-07-09 印第安纳大学研究及科技有限公司 基于gip的混合激动剂用于治疗代谢紊乱和肥胖症
EP2346906A4 (en) * 2008-10-15 2013-04-24 Angiochem Inc CONJUGATES FROM GLP-1 AGONISTS AND THEIR USE
EP2528618A4 (en) 2010-01-27 2015-05-27 Univ Indiana Res & Tech Corp GLUCAGON ANTAGONISTE AND GIP AGONISTS CONJUGATES AND COMPOSITIONS FOR THE TREATMENT OF METABOLISM DISEASES AND ADIPOSITAS
DK2621945T3 (en) 2010-09-28 2018-05-22 Nono Inc ND2 PEPTIDES AND METHODS OF TREATING NEUROLOGICAL DISEASE
TWI559929B (en) 2011-09-01 2016-12-01 Sanofi Aventis Deutschland Pharmaceutical composition for use in the treatment of a neurodegenerative disease
US9579358B2 (en) 2011-10-10 2017-02-28 Lancaster University Business Enterprises Limited Compositions for binding to amyloid proteins
TWI689515B (zh) * 2012-05-03 2020-04-01 丹麥商西蘭製藥公司 Gip-glp-1雙重促效劑化合物及方法
TWI599575B (zh) * 2012-06-21 2017-09-21 印第安納大學科技研究公司 表現gip受體活性之胰高血糖素類似物
CN114057895A (zh) * 2014-05-28 2022-02-18 诺诺公司 TAT-NR2B9c的氯盐
GB2528436A (en) * 2014-07-15 2016-01-27 Lancaster Univ Business Entpr Ltd Treatment of neurological diseases
US20160143920A1 (en) * 2014-10-22 2016-05-26 Morris Notelovitz Composition, formulations and methods of making and using botanicals and natural compounds for the promotion of healthy brain aging
US20170112897A1 (en) 2015-10-23 2017-04-27 Cedars-Sinai Medical Center Methods for treating brain insulin resistance
JP2019504106A (ja) 2015-10-28 2019-02-14 タフツ ユニバーシティー タンパク質分解安定性が改善された新規ポリペプチド並びにその調製方法及び使用方法
WO2017210168A1 (en) 2016-06-02 2017-12-07 Indiana University Research And Technology Corporation Aqueously soluble and chemically stable depsi glucagon agonists
GB201620611D0 (en) * 2016-12-05 2017-01-18 Univ Of Lancaster Treatment of neurological diseases

Also Published As

Publication number Publication date
RU2019118165A (ru) 2021-01-11
JP2020504713A (ja) 2020-02-13
LT3548061T (lt) 2020-12-28
RU2755997C2 (ru) 2021-09-24
CN110312520A (zh) 2019-10-08
HRP20201959T1 (hr) 2021-04-16
KR102600128B1 (ko) 2023-11-08
EP3548061B1 (en) 2020-09-09
US20200079832A1 (en) 2020-03-12
WO2018104718A1 (en) 2018-06-14
GB201620611D0 (en) 2017-01-18
ZA201903003B (en) 2019-12-18
US11851468B2 (en) 2023-12-26
EP3548061A1 (en) 2019-10-09
DK3548061T3 (da) 2020-12-14
AU2017371811A1 (en) 2019-06-13
US20220033457A1 (en) 2022-02-03
RS61230B1 (sr) 2021-01-29
CL2019001512A1 (es) 2019-11-22
RU2019118165A3 (it) 2021-03-05
MX2019006495A (es) 2019-11-05
CN110312520B (zh) 2023-01-24
AU2017371811B2 (en) 2022-03-10
CY1123623T1 (el) 2022-03-24
CA3044797A1 (en) 2018-06-14
SI3548061T1 (sl) 2021-04-30
CO2019006979A2 (es) 2019-09-09
US11220534B2 (en) 2022-01-11
PT3548061T (pt) 2020-11-24
ES2833408T3 (es) 2021-06-15
HUE052766T2 (hu) 2021-05-28
KR20190101367A (ko) 2019-08-30
JP7099729B2 (ja) 2022-07-12
BR112019011462A2 (pt) 2019-10-22

Similar Documents

Publication Publication Date Title
HRP20190117T1 (hr) iRNK TERAPIJA ZA LIJEČENJE BOLESTI OKA
ZA201903003B (en) Treatment of neurological diseases
HUE060671T2 (hu) Eljárás fibrotikus betegségek kezelésére
IL269106A (en) Methods for the treatment of neurodegenerative diseases
HK1258994A1 (zh) 用於疾病治療的方法
IL255506A (en) A method for treating a neurological disease
GB201412578D0 (en) Treatment of neurological diseases
GB201516905D0 (en) Treatment of Neurodegenerative diseases
GB201805100D0 (en) Treatment of sarcopenic diseases
EP3413898A4 (en) USE OF TREHALOSIS FOR THE TREATMENT OF NEUROLOGICAL DISEASES
GB201714307D0 (en) Treatment of neurodegenerative diseases
IL263080B (en) Treatment of neurological disorders
GB201607388D0 (en) Treatment of impulsivity-related disorders
IL282360A (en) Treatment for neurological diseases
IL259381B (en) Miravegron for the treatment of retinal diseases
GB201714311D0 (en) Treatment of neurodegenerative diseases
GB201714303D0 (en) Treatment of neurodegenerative diseases
PL3302463T3 (pl) Zastosowanie 3 deoksyantocyjanidyn w leczeniu chorób oczu
GB201706662D0 (en) Treatment of neurological diseases
GB201715763D0 (en) Treatment of neurological disease
IL263837A (en) Treatment of ocular disease
GB201704666D0 (en) Treatment of neurodegenerative diseases
GB201604253D0 (en) Treatment of genetic diseases
GB201621398D0 (en) Treatment of emt-associated disease
GB201517565D0 (en) Treatment of genetic diseases