SK281297B6 - Spôsob prípravy beta-fenylizoserínu, jeho analógov a medziprodukt - Google Patents

Spôsob prípravy beta-fenylizoserínu, jeho analógov a medziprodukt Download PDF

Info

Publication number: SK281297B6
Authority: SK; Slovakia
Prior art keywords: phenyl; group; formula; alkyl; carbon atoms
Prior art date: 1992-03-10

Application number

SK1085-94A

Other languages

English (en)

Slovak (sk)

Other versions

SK108594A3 (en

Inventor

Jean-Dominique Bourzat

Alain Commercon

Original Assignee

Rhone-Poulenc Rorer S. A.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-03-10

Filing date

1993-03-08

Publication date

2001-02-12

1993-03-08 Application filed by Rhone-Poulenc Rorer S. A. filed Critical Rhone-Poulenc Rorer S. A.

1995-02-08 Publication of SK108594A3 publication Critical patent/SK108594A3/sk

2001-02-12 Publication of SK281297B6 publication Critical patent/SK281297B6/sk

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
- C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
- C07C227/18—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/22—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from lactams, cyclic ketones or cyclic oximes, e.g. by reactions involving Beckmann rearrangement
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Epoxy Compounds (AREA)
Steroid Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

SK1085-94A 1992-03-10 1993-03-08 Spôsob prípravy beta-fenylizoserínu, jeho analógov a medziprodukt SK281297B6 (sk)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR9202821A FR2688499B1 (fr)	1992-03-10	1992-03-10	Procede de preparation de la beta-phenylisoserine et de ses analogues.
PCT/FR1993/000224 WO1993017997A1 (fr)	1992-03-10	1993-03-08	PROCEDE DE PREPARATION DE LA β-PHENYLISOSERINE ET DE SES ANALOGUES

Publications (2)

Publication Number	Publication Date
SK108594A3 SK108594A3 (en)	1995-02-08
SK281297B6 true SK281297B6 (sk)	2001-02-12

Family

ID=9427518

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SK1085-94A SK281297B6 (sk)	1992-03-10	1993-03-08	Spôsob prípravy beta-fenylizoserínu, jeho analógov a medziprodukt

Country Status (25)

Country	Link
US (2)	US5608102A (fi)
EP (1)	EP0630365B1 (fi)
JP (1)	JP3278768B2 (fi)
KR (1)	KR100272650B1 (fi)
AT (1)	ATE159512T1 (fi)
AU (1)	AU667886B2 (fi)
CA (1)	CA2130333C (fi)
CZ (1)	CZ283613B6 (fi)
DE (1)	DE69314779T2 (fi)
DK (1)	DK0630365T3 (fi)
ES (1)	ES2109509T3 (fi)
FI (1)	FI113640B (fi)
FR (1)	FR2688499B1 (fi)
GE (1)	GEP19981430B (fi)
GR (1)	GR3025117T3 (fi)
HU (1)	HU213621B (fi)
MX (1)	MX9301268A (fi)
NO (1)	NO304515B1 (fi)
NZ (1)	NZ249899A (fi)
PL (1)	PL171551B1 (fi)
RU (1)	RU2103258C1 (fi)
SK (1)	SK281297B6 (fi)
TW (1)	TW252971B (fi)
WO (1)	WO1993017997A1 (fi)
ZA (1)	ZA931677B (fi)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0773938B1 (en) *	1994-07-26	1999-02-03	INDENA S.p.A.	Semi-synthetic taxanes with anti-tumoural activity
US6765015B2 (en) *	1995-12-13	2004-07-20	Xechem International, Inc.	Halogenated paclitaxel derivatives
DK1019347T3 (da) *	1997-08-21	2003-07-21	Univ Florida State	Fremgangsmåde til syntesen af taxaner
AU1701699A (en) *	1997-11-19	1999-06-07	Xechem International, Inc.	Halogenated paclitaxel derivatives
ITMI991483A1 (it) *	1999-07-06	2001-01-06	Indena Spa	Derivati tassanici e procedimenti per la loro preparazione
EP1229934B1 (en)	1999-10-01	2014-03-05	Immunogen, Inc.	Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents
JP2002080435A (ja) *	2000-06-26	2002-03-19	Kanegafuchi Chem Ind Co Ltd	３−アミノ−２−ヒドロキシプロピオン酸誘導体の製造法
EP1375495B1 (en) *	2001-03-07	2008-09-03	Daiichi Sankyo Company, Limited	Method for producing a 2-azetidinone derivative
DK1961735T3 (da) *	2007-02-22	2010-03-29	Indena Spa	Fremgangsmåde til fremstilling af (2R,3S)-3-phenylisoserinmethylesteracetatsalt
DK2080764T3 (da)	2008-01-18	2012-09-24	Indena Spa	Faste former af ortataxel
CN102408356A (zh) *	2011-09-28	2012-04-11	北京东方协和医药生物技术有限公司	一种多西他赛手性侧链中间体的制备方法
EP3102195B1 (en) *	2014-02-03	2021-10-06	Quadriga Biosciences, Inc.	Beta-substituted beta-amino acids and analogs as chemotherapeutic agents
CN111100026A (zh) *	2019-12-30	2020-05-05	重庆市碚圣医药科技股份有限公司	一种紫杉醇恶唑环侧链中间体的制备方法
CN112574134A (zh) *	2020-12-30	2021-03-30	重庆市碚圣医药科技股份有限公司	一种多西紫杉醇侧链的合成方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2629819B1 (fr) *	1988-04-06	1990-11-16	Rhone Poulenc Sante	Procede de preparation de derives de la baccatine iii et de la desacetyl-10 baccatine iii
IT1231751B (it) *	1989-04-12	1991-12-21	Sigma Tau Ind Farmaceuti	Procedimento per la produzione di r(+) amminocarnitina e s(-) amminocarnitina
US5175315A (en) *	1989-05-31	1992-12-29	Florida State University	Method for preparation of taxol using β-lactam
US5304670A (en) *	1989-08-23	1994-04-19	Centre National De La Recherche Scientifique	Process for the enantioselective preparation of phenylisoserine derivatives
FR2658510B1 (fr) *	1990-02-21	1992-04-30	Rhone Poulenc Sante	Nouveau derive de la beta-phenylisoserine, sa preparation et son emploi.
US5294737A (en) *	1992-02-27	1994-03-15	The Research Foundation State University Of New York	Process for the production of chiral hydroxy-β-lactams and hydroxyamino acids derived therefrom

1992
- 1992-03-10 FR FR9202821A patent/FR2688499B1/fr not_active Expired - Fee Related
1993
- 1993-03-08 MX MX9301268A patent/MX9301268A/es unknown
- 1993-03-08 DK DK93918746.4T patent/DK0630365T3/da active
- 1993-03-08 WO PCT/FR1993/000224 patent/WO1993017997A1/fr active IP Right Grant
- 1993-03-08 HU HU9402590A patent/HU213621B/hu unknown
- 1993-03-08 DE DE69314779T patent/DE69314779T2/de not_active Expired - Lifetime
- 1993-03-08 ES ES93918746T patent/ES2109509T3/es not_active Expired - Lifetime
- 1993-03-08 GE GEAP19932472A patent/GEP19981430B/en unknown
- 1993-03-08 EP EP93918746A patent/EP0630365B1/fr not_active Expired - Lifetime
- 1993-03-08 KR KR1019940703156A patent/KR100272650B1/ko not_active IP Right Cessation
- 1993-03-08 JP JP51539493A patent/JP3278768B2/ja not_active Expired - Lifetime
- 1993-03-08 NZ NZ249899A patent/NZ249899A/en not_active IP Right Cessation
- 1993-03-08 PL PL93305059A patent/PL171551B1/pl unknown
- 1993-03-08 AU AU37557/93A patent/AU667886B2/en not_active Expired
- 1993-03-08 RU RU94045799A patent/RU2103258C1/ru active
- 1993-03-08 SK SK1085-94A patent/SK281297B6/sk not_active IP Right Cessation
- 1993-03-08 CZ CZ942185A patent/CZ283613B6/cs not_active IP Right Cessation
- 1993-03-08 AT AT93918746T patent/ATE159512T1/de active
- 1993-03-08 CA CA002130333A patent/CA2130333C/fr not_active Expired - Lifetime
- 1993-03-08 US US08/295,677 patent/US5608102A/en not_active Expired - Lifetime
- 1993-03-09 ZA ZA931677A patent/ZA931677B/xx unknown
- 1993-03-10 TW TW082101775A patent/TW252971B/zh not_active IP Right Cessation
1994
- 1994-09-05 NO NO943280A patent/NO304515B1/no not_active IP Right Cessation
- 1994-09-09 FI FI944169A patent/FI113640B/fi not_active IP Right Cessation
1996
- 1996-08-23 US US08/697,420 patent/US5763628A/en not_active Expired - Lifetime
1997
- 1997-10-23 GR GR970401615T patent/GR3025117T3/el unknown

Also Published As

Publication number	Publication date
CZ283613B6 (cs)	1998-05-13
DE69314779D1 (de)	1997-11-27
NZ249899A (en)	1996-01-26
HU213621B (en)	1997-08-28
JPH07504425A (ja)	1995-05-18
US5608102A (en)	1997-03-04
CA2130333A1 (fr)	1993-09-16
RU94045799A (ru)	1996-07-20
DE69314779T2 (de)	1998-02-26
HU9402590D0 (en)	1994-11-28
AU3755793A (en)	1993-10-05
SK108594A3 (en)	1995-02-08
NO943280D0 (no)	1994-09-05
KR100272650B1 (ko)	2000-11-15
RU2103258C1 (ru)	1998-01-27
GEP19981430B (en)	1998-10-30
FR2688499A1 (fr)	1993-09-17
EP0630365A1 (fr)	1994-12-28
EP0630365B1 (fr)	1997-10-22
AU667886B2 (en)	1996-04-18
CA2130333C (fr)	2002-11-26
HUT68540A (en)	1995-06-28
DK0630365T3 (da)	1998-03-02
FI944169A0 (fi)	1994-09-09
FI113640B (fi)	2004-05-31
ES2109509T3 (es)	1998-01-16
FI944169A (fi)	1994-09-09
NO943280L (no)	1994-09-05
JP3278768B2 (ja)	2002-04-30
WO1993017997A1 (fr)	1993-09-16
ZA931677B (en)	1993-10-06
MX9301268A (es)	1993-09-01
TW252971B (fi)	1995-08-01
GR3025117T3 (en)	1998-01-30
FR2688499B1 (fr)	1994-05-06
PL171551B1 (pl)	1997-05-30
ATE159512T1 (de)	1997-11-15
KR950700234A (ko)	1995-01-16
NO304515B1 (no)	1999-01-04
US5763628A (en)	1998-06-09
CZ218594A3 (en)	1995-11-15

Publication	Publication Date	Title
US5677462A (en)	1997-10-14	Process for preparing taxane derivatives
JP3014762B2 (ja)	2000-02-28	タキサン誘導体の製造法
JP3064419B2 (ja)	2000-07-12	バッカチン▲ｉｉｉ▼及び１０−デアセチルバッカチン▲ｉｉｉ▼のエステル化のための新規な方法
DE69128971T2 (de)	1998-09-24	Verfahren zur Herstellung von Taxanderivaten und deren Zwischenprodukte
SK280624B6 (sk)	2000-05-16	Spôsob prípravy derivátov taxánu a medziprodukty n
SK281297B6 (sk)	2001-02-12	Spôsob prípravy beta-fenylizoserínu, jeho analógov a medziprodukt
JP3633619B2 (ja)	2005-03-30	β−フェニルイソセリン誘導体の製造法
SK92794A3 (en)	1995-04-12	Baccatine iii and 10-deacetyl baccatine iii derivatives, their preparation and pharmaceutical compositions containing same
US5939561A (en)	1999-08-17	Process for the preparation of β-phenylisoserine and β-lactam and their analogues
KR100225535B1 (ko)	1999-10-15	파클리탁셀의 제조방법
DE69406451T2 (de)	1998-02-26	Verfahren zur herstellung von n-carbonylarylimine als zwischenprodukte in der synthese von therapeutisch aktiven taxol-derivaten
SK126496A3 (en)	1997-05-07	Process for the preparation of 7-hydroxy taxanes
DE69311736T2 (de)	1997-11-13	Verfahren zur herstellung einer 1,3-oxazolidin-5-carbonsäure

Legal Events

Date	Code	Title	Description
2011-09-05	QB4A	Licence contract registered or granted	Free format text: EXCLUSIVE LICENCE Name of requester: MAY & BAKER LTD., WEST MALLING, KENT, GB Effective date: 20070101 Free format text: NON-EXCLUSIVE LICENCE Name of requester: SANOFI-AVENTIS PHARMA SLOVAKIA S.R.O., BRATISL, SK Effective date: 20100420
2013-05-03	MK4A	Patent expired	Expiry date: 20130308

Date

Code

Title

Description

2011-09-05

QB4A

Licence contract registered or granted

Free format text: EXCLUSIVE LICENCE

Name of requester: MAY & BAKER LTD., WEST MALLING, KENT, GB

Effective date: 20070101

Free format text: NON-EXCLUSIVE LICENCE

Name of requester: SANOFI-AVENTIS PHARMA SLOVAKIA S.R.O., BRATISL, SK

Effective date: 20100420

2013-05-03

MK4A

Patent expired

Expiry date: 20130308