SK280028B6 - Plazmidy, spôsob ich výroby a ich použitie na získ - Google Patents

Plazmidy, spôsob ich výroby a ich použitie na získ Download PDF

Info

Publication number: SK280028B6
Authority: SK; Slovakia
Prior art keywords: plasmid; coli; pbf; rscu; plasmids
Prior art date: 1989-07-19

Application number

SK3067-90A

Other languages

English (en)

Slovak (sk)

Other versions

SK306790A3 (en

Inventor

Regina E. Brigelius-Floh�

Leopold Floh

Wolfgang Hillen

Gerd J. Steffens

Wolfgang Strassburger

Martin R.F. Wilhelm

Original Assignee

Grnenthal Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-07-19

Filing date

1990-06-20

Publication date

1999-07-12

1990-06-20 Application filed by Grnenthal Gmbh filed Critical Grnenthal Gmbh

1999-07-12 Publication of SK306790A3 publication Critical patent/SK306790A3/sk

1999-07-12 Publication of SK280028B6 publication Critical patent/SK280028B6/sk

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
- C12N9/6456—Plasminogen activators
- C12N9/6462—Plasminogen activators u-Plasminogen activator (3.4.21.73), i.e. urokinase
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/67—General methods for enhancing the expression
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21073—Serine endopeptidases (3.4.21) u-Plasminogen activator (3.4.21.73), i.e. urokinase

Landscapes

Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Wood Science & Technology (AREA)
Zoology (AREA)
Biomedical Technology (AREA)
General Engineering & Computer Science (AREA)
Biotechnology (AREA)
General Health & Medical Sciences (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Microbiology (AREA)
Physics & Mathematics (AREA)
Biophysics (AREA)
Plant Pathology (AREA)
Medicinal Chemistry (AREA)
Enzymes And Modification Thereof (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Saccharide Compounds (AREA)
Peptides Or Proteins (AREA)

SK3067-90A 1989-07-19 1990-06-20 Plazmidy, spôsob ich výroby a ich použitie na získ SK280028B6 (sk)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE3923866		1989-07-19

Publications (2)

Publication Number	Publication Date
SK306790A3 SK306790A3 (en)	1999-07-12
SK280028B6 true SK280028B6 (sk)	1999-07-12

Family

ID=6385369

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SK3067-90A SK280028B6 (sk)	1989-07-19	1990-06-20	Plazmidy, spôsob ich výroby a ich použitie na získ

Country Status (30)

Country	Link
US (1)	US5637503A (pl)
EP (1)	EP0408945B1 (pl)
JP (1)	JP3236284B2 (pl)
KR (1)	KR0167761B1 (pl)
AT (1)	ATE131534T1 (pl)
AU (1)	AU631662B2 (pl)
CA (1)	CA2020656C (pl)
DD (1)	DD298426A5 (pl)
DE (2)	DE4020438A1 (pl)
DK (1)	DK0408945T3 (pl)
ES (1)	ES2083399T3 (pl)
FI (1)	FI102386B1 (pl)
GR (1)	GR3019294T3 (pl)
HK (1)	HK1005193A1 (pl)
HR (1)	HRP920596B1 (pl)
HU (1)	HU214243B (pl)
IE (1)	IE901849A1 (pl)
IL (1)	IL94529A (pl)
LT (1)	LT3611B (pl)
LV (1)	LV10120B (pl)
MT (1)	MTP1063B (pl)
NO (1)	NO304952B1 (pl)
NZ (1)	NZ234542A (pl)
PL (1)	PL166199B1 (pl)
PT (1)	PT94776B (pl)
RU (1)	RU2073720C1 (pl)
SI (1)	SI9011347B (pl)
SK (1)	SK280028B6 (pl)
YU (1)	YU48371B (pl)
ZA (1)	ZA904006B (pl)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2067226A1 (pl) *	1969-11-27	1971-08-20	Cefilac
DE4101736A1 (de) *	1991-01-22	1992-07-23	Gruenenthal Gmbh	Neue als plasminogenaktivatoren einsetzbare polypeptide, dafuer codierende plasmide und verfahren zu deren herstellung und deren verwendung
DE4440892A1 (de) *	1994-11-17	1996-05-23	Gruenenthal Gmbh	Proteine mit fibrinolytischen und gerinnungshemmenden Eigenschaften
DE4442665A1 (de) *	1994-11-30	1996-06-05	Gruenenthal Gmbh	Chimäre Proteine mit fibrinolytischen und thrombinhemmenden Eigenschaften
KR100467034B1 (ko) *	1996-12-27	2006-04-07	주식회사 엘지생활건강	압축성형타입오일케익화장료및그의제조방법
KR100372233B1 (ko) *	1997-03-12	2003-06-11	주식회사 코리아나화장품	미백 파우더, 그의 제조방법 및 그를 함유하는 메이크업 미백 화장료
KR100341638B1 (ko) *	2000-03-17	2002-06-22	유상옥,송운한	기능성 표면처리 분체의 제조 방법 및 이를 함유하는메이크업 화장료 조성물
JP4124639B2 (ja)	2002-12-17	2008-07-23	株式会社日本触媒	大腸菌を用いたｓ−ヒドロキシニトリルリアーゼの製造方法
US7906276B2 (en) *	2004-06-30	2011-03-15	Kimberly-Clark Worldwide, Inc.	Enzymatic detection techniques
CN102016045A (zh)	2007-05-02	2011-04-13	梅瑞尔有限公司	具有改善的表达和稳定性的dna质粒
RU2553533C2 (ru) *	2013-10-23	2015-06-20	Общество с ограниченной ответственностью "Международный биотехнологический центр "Генериум" ("МБЦ "Генериум")	Способ выделения и очистки рекомбинантной человеческой проурокиназы м5
CN104555732A (zh) *	2015-01-18	2015-04-29	河南省中原起重机械总厂	一种多功能门式起重机

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4370417A (en) *	1980-04-03	1983-01-25	Abbott Laboratories	Recombinant deoxyribonucleic acid which codes for plasminogen activator
US4558010A (en) *	1980-04-03	1985-12-10	Abbott Laboratories	Recombinant deoxyribonucleic acid which codes for plasminogen activator and method of making plasminogen activator protein therefrom
IL68366A (en) *	1982-04-15	1990-08-31	Genentech Inc	Process for expressing a gene encoding a protein comprising the enzymatic portion of human urokinase in a microorganism or cell culture
US4710464A (en) *	1984-09-27	1987-12-01	Eli Lilly And Company	Transcription terminators
EP0210279B1 (en) *	1985-01-25	1991-08-14	Sagami Chemical Research Center	Stabilized human prourokinase
FR2594845B1 (fr) *	1986-02-21	1989-12-01	Genetica	Preparation par voie microbiologique de l'activateur tissulaire humain du plasminogene (t-pa) et conversion de l'enzyme ainsi obtenue en sa forme active
FI100106B (fi) *	1986-12-05	1997-09-30	Novartis Ag	Menetelmä plasminogeenin yksisäikeisen yhdistelmäaktivaattorin valmist amiseksi
HU208712B (en) *	1987-08-10	1993-12-28	Lepetit Spa	Method for preparing single or double strained glycolised human urokinase and pharmaceutical composition comprising same
WO1989003886A1 (en) *	1987-10-30	1989-05-05	Oncogen, A Limited Partnership	Expression systems for preparation of polypeptides in prokaryotic cells

1990
- 1990-05-22 IE IE184990A patent/IE901849A1/en not_active Application Discontinuation
- 1990-05-23 ZA ZA904006A patent/ZA904006B/xx unknown
- 1990-05-28 IL IL94529A patent/IL94529A/xx not_active IP Right Cessation
- 1990-06-19 NO NO902720A patent/NO304952B1/no not_active IP Right Cessation
- 1990-06-20 SK SK3067-90A patent/SK280028B6/sk unknown
- 1990-06-25 HU HU903970A patent/HU214243B/hu not_active IP Right Cessation
- 1990-06-27 DE DE4020438A patent/DE4020438A1/de not_active Withdrawn
- 1990-06-28 MT MT1063A patent/MTP1063B/xx unknown
- 1990-06-29 DE DE59009961T patent/DE59009961D1/de not_active Expired - Fee Related
- 1990-06-29 ES ES90112400T patent/ES2083399T3/es not_active Expired - Lifetime
- 1990-06-29 AT AT90112400T patent/ATE131534T1/de not_active IP Right Cessation
- 1990-06-29 EP EP90112400A patent/EP0408945B1/de not_active Expired - Lifetime
- 1990-06-29 DK DK90112400.8T patent/DK0408945T3/da active
- 1990-07-06 CA CA002020656A patent/CA2020656C/en not_active Expired - Fee Related
- 1990-07-09 AU AU58832/90A patent/AU631662B2/en not_active Ceased
- 1990-07-11 SI SI9011347A patent/SI9011347B/sl unknown
- 1990-07-11 YU YU134790A patent/YU48371B/sh unknown
- 1990-07-12 US US07/551,907 patent/US5637503A/en not_active Expired - Fee Related
- 1990-07-17 NZ NZ234542A patent/NZ234542A/xx unknown
- 1990-07-17 PL PL90286087A patent/PL166199B1/pl unknown
- 1990-07-18 FI FI903640A patent/FI102386B1/fi not_active IP Right Cessation
- 1990-07-18 DD DD90342894A patent/DD298426A5/de not_active IP Right Cessation
- 1990-07-18 KR KR1019900010860A patent/KR0167761B1/ko not_active IP Right Cessation
- 1990-07-18 RU SU4831114/13A patent/RU2073720C1/ru not_active IP Right Cessation
- 1990-07-18 JP JP18816990A patent/JP3236284B2/ja not_active Expired - Fee Related
- 1990-07-19 PT PT94776A patent/PT94776B/pt not_active IP Right Cessation
1992
- 1992-09-29 HR HRP-1347/90A patent/HRP920596B1/xx not_active IP Right Cessation
- 1992-11-13 LV LVP-92-204A patent/LV10120B/lv unknown
1993
- 1993-07-12 LT LTIP776A patent/LT3611B/lt not_active IP Right Cessation
1996
- 1996-03-13 GR GR960400698T patent/GR3019294T3/el unknown
1998
- 1998-05-19 HK HK98104295A patent/HK1005193A1/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
LV10120B (en)	1994-10-20
AU5883290A (en)	1991-01-24
NO304952B1 (no)	1999-03-08
PT94776A (pt)	1991-03-20
SI9011347A (sl)	1998-04-30
CA2020656C (en)	2001-05-22
PL166199B1 (pl)	1995-04-28
GR3019294T3 (en)	1996-06-30
JP3236284B2 (ja)	2001-12-10
LT3611B (en)	1995-12-27
PT94776B (pt)	1997-09-30
KR910003105A (ko)	1991-02-26
KR0167761B1 (ko)	1999-01-15
ES2083399T3 (es)	1996-04-16
HUT54211A (en)	1991-01-28
ATE131534T1 (de)	1995-12-15
CA2020656A1 (en)	1991-01-20
NZ234542A (en)	1991-09-25
HRP920596A2 (en)	1998-06-30
HU903970D0 (en)	1990-11-28
LTIP776A (en)	1995-01-31
IE901849A1 (en)	1991-06-19
RU2073720C1 (ru)	1997-02-20
DE59009961D1 (de)	1996-01-25
US5637503A (en)	1997-06-10
EP0408945B1 (de)	1995-12-13
SK306790A3 (en)	1999-07-12
IL94529A (en)	1997-11-20
FI903640A0 (fi)	1990-07-18
NO902720L (no)	1991-01-21
SI9011347B (sl)	1999-02-28
NO902720D0 (no)	1990-06-19
DK0408945T3 (da)	1996-04-09
FI102386B (fi)	1998-11-30
EP0408945A1 (de)	1991-01-23
IL94529A0 (en)	1991-03-10
YU134790A (sh)	1992-12-21
HU214243B (hu)	1998-03-02
DD298426A5 (de)	1992-02-20
ZA904006B (en)	1991-03-27
MTP1063B (en)	1991-04-08
DE4020438A1 (de)	1991-01-31
HK1005193A1 (en)	1998-12-24
JPH0365189A (ja)	1991-03-20
YU48371B (sh)	1998-07-10
FI102386B1 (fi)	1998-11-30
AU631662B2 (en)	1992-12-03
PL286087A1 (en)	1991-03-11
HRP920596B1 (en)	1999-12-31
LV10120A (lv)	1994-05-10

Publication	Publication Date	Title
Holmes et al.	1985	Cloning and expression of the gene for pro-urokinase in Escherichia coli
JP2610783B2 (ja)	1997-05-14	ポリクリングルプラスミノーゲン活性化因子をコードする遺伝子およびそれを含有するベクター
KR930002889B1 (ko)	1993-04-12	효모에 의한 조직 플라스미노겐 활성화제의 제조방법
SK280028B6 (sk)	1999-07-12	Plazmidy, spôsob ich výroby a ich použitie na získ
EP0277313B1 (en)	1997-01-22	Hybrid plasminogen activators
McCaman et al.	1985	Enzymatic properties and processing of bovine prochymosin synthesized in Escherichia coli
CA1340867C (en)	2000-01-04	Expression plasmids for improved production of heterologus protein in bacteria
Ohsuye et al.	1983	Expression of chemically synthesized α-neo-endorphin gene fused to E. coli alkaline phosphatase
IE914040A1 (en)	1992-07-29	New polypeptides, plasmids coding for these polypeptides and¹processes for their manufacture and use
CZ287994B6 (cs)	2001-03-14	Plazmidy, způsob jejich výroby a jejich použití pro získávání aktivátoru plazminogenu
KR20030060384A (ko)	2003-07-16	인간 혈청 알부민-팀프-2 융합 단백질 발현시스템 및재조합 인간 혈청 알부민-팀프-2 융합 단백질
EP0370063A1 (en)	1990-05-30	Expression vectors and method for their construction
US5242819A (en)	1993-09-07	DNA molecules encoding hybrid proteins of tissue plasminogen activator and urokinase
US5580559A (en)	1996-12-03	Hybrid plasminogen activator
EP0232544A2 (en)	1987-08-19	Process for producing physiologically active substances
JPS62158487A (ja)	1987-07-14	突然変異体コ−デイング配列
RU2140453C1 (ru)	1999-10-27	Рекомбинантная плазмидная днк p ua bc22, кодирующая модифицированный активатор плазминогена урокиназного типа, нетранслируемый днк-элемент - искусственная межгенная последовательность мгп14 и штамм бактерий escherichia coli - продуцент модифицированного активатора плазминогена урокиназного типа
USH2055H1 (en)	2002-12-03	Expression of tissue-type plasminogen activator in bacteria
HU202280B (en)	1991-02-28	Process for producing functional human urokinase proteins
SI8810195A (sl)	1996-08-31	Hibridni proteini
JPH05336965A (ja)	1993-12-21	ヒトプロウロキナーゼ誘導体
JPH0817704B2 (ja)	1996-02-28	外来遺伝子産物の生産方法