SK18962000A3 - Tetrahydronaftyridinylkarboxamidové zlúčeniny, spôsob ich výroby, farmaceutický prostriedok s ich obsahom a ich použitie - Google Patents

Tetrahydronaftyridinylkarboxamidové zlúčeniny, spôsob ich výroby, farmaceutický prostriedok s ich obsahom a ich použitie Download PDF

Info

Publication number: SK18962000A3
Authority: SK; Slovakia
Prior art keywords: tetrahydro; naphthyridin; trimethyl; alkyl; disorders
Prior art date: 1998-06-12

Application number

SK1896-2000A

Other languages

English (en)

Slovak (sk)

Inventor

John David Harling

Frank Peter Harrington

Mervyn Thompson

Original Assignee

Smithkline Beecham Plc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-06-12

Filing date

1999-06-09

Publication date

2001-08-06

1999-06-09 Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc

2001-08-06 Publication of SK18962000A3 publication Critical patent/SK18962000A3/sk

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/10—Spiro-condensed systems

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Psychiatry (AREA)
Addiction (AREA)
Pain & Pain Management (AREA)
Physical Education & Sports Medicine (AREA)
Psychology (AREA)
Orthopedic Medicine & Surgery (AREA)
Virology (AREA)
Immunology (AREA)
Molecular Biology (AREA)
Hospice & Palliative Care (AREA)
Anesthesiology (AREA)
AIDS & HIV (AREA)
Tropical Medicine & Parasitology (AREA)
Communicable Diseases (AREA)
Rheumatology (AREA)
Oncology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

SK1896-2000A 1998-06-12 1999-06-09 Tetrahydronaftyridinylkarboxamidové zlúčeniny, spôsob ich výroby, farmaceutický prostriedok s ich obsahom a ich použitie SK18962000A3 (sk)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB9812683.2A GB9812683D0 (en)	1998-06-12	1998-06-12	Novel compounds
PCT/GB1999/001826 WO1999065903A1 (en)	1998-06-12	1999-06-09	Tetrahydronaphthyridinyl-carboxamides having anti-convulsant activity

Publications (1)

Publication Number	Publication Date
SK18962000A3 true SK18962000A3 (sk)	2001-08-06

Family

ID=10833636

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SK1896-2000A SK18962000A3 (sk)	1998-06-12	1999-06-09	Tetrahydronaftyridinylkarboxamidové zlúčeniny, spôsob ich výroby, farmaceutický prostriedok s ich obsahom a ich použitie

Country Status (31)

Country	Link
US (2)	US6410555B1 (xx)
EP (1)	EP1084122B1 (xx)
JP (1)	JP2002518390A (xx)
KR (1)	KR20010052792A (xx)
CN (1)	CN1311789A (xx)
AP (1)	AP2000002009A0 (xx)
AR (1)	AR018656A1 (xx)
AT (1)	ATE252579T1 (xx)
AU (1)	AU750470B2 (xx)
BG (1)	BG105126A (xx)
BR (1)	BR9911110A (xx)
CA (1)	CA2334900A1 (xx)
CO (1)	CO5040081A1 (xx)
CZ (1)	CZ293010B6 (xx)
DE (1)	DE69912278T2 (xx)
EA (1)	EA200100033A1 (xx)
ES (1)	ES2209524T3 (xx)
GB (1)	GB9812683D0 (xx)
HU (1)	HUP0102773A3 (xx)
ID (1)	ID27593A (xx)
IL (1)	IL140171A0 (xx)
MA (1)	MA26646A1 (xx)
NO (1)	NO20006269L (xx)
NZ (1)	NZ508799A (xx)
PE (1)	PE20000727A1 (xx)
PL (1)	PL344791A1 (xx)
SK (1)	SK18962000A3 (xx)
TR (1)	TR200003694T2 (xx)
TW (1)	TW495510B (xx)
WO (1)	WO1999065903A1 (xx)
ZA (1)	ZA200007397B (xx)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9812683D0 (en) *	1998-06-12	1998-08-12	Smithkline Beecham Plc	Novel compounds
ATE228358T1 (de) *	2001-03-21	2002-12-15	Sanol Arznei Schwarz Gmbh	Neue verwendung einer klasse von peptidverbindungen zur behandlung von allodynie oder andere arten von chronischen oder phantomschmerzen
CA2624625A1 (en) *	2005-11-04	2007-05-10	Pfizer Limited	Tetrahydronaphthyridine derivative
KR20150047597A (ko) *	2012-08-27	2015-05-04	어레이 바이오파마 인크.	과증식성 질환의 치료를 위한 세린/트레오닌 키나아제 억제제

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9112721D0 (en)	1991-06-13	1991-07-31	Smithkline Beecham Plc	Novel treatment
AU729124B2 (en)	1996-06-17	2001-01-25	Smithkline Beecham Plc	Substituted benzamide derivatives and their use as anticonvulsants
GB9711257D0 (en) *	1997-05-30	1997-07-30	Smithkline Beecham Plc	Novel compounds
GB9812683D0 (en) *	1998-06-12	1998-08-12	Smithkline Beecham Plc	Novel compounds

1998
- 1998-06-12 GB GBGB9812683.2A patent/GB9812683D0/en not_active Ceased
1999
- 1999-06-09 DE DE69912278T patent/DE69912278T2/de not_active Expired - Fee Related
- 1999-06-09 AT AT99957056T patent/ATE252579T1/de not_active IP Right Cessation
- 1999-06-09 CA CA002334900A patent/CA2334900A1/en not_active Abandoned
- 1999-06-09 AP APAP/P/2000/002009A patent/AP2000002009A0/en unknown
- 1999-06-09 JP JP2000554728A patent/JP2002518390A/ja active Pending
- 1999-06-09 KR KR1020007014099A patent/KR20010052792A/ko not_active Application Discontinuation
- 1999-06-09 PL PL99344791A patent/PL344791A1/xx not_active Application Discontinuation
- 1999-06-09 IL IL14017199A patent/IL140171A0/xx unknown
- 1999-06-09 CN CN99809413A patent/CN1311789A/zh active Pending
- 1999-06-09 EA EA200100033A patent/EA200100033A1/ru unknown
- 1999-06-09 CZ CZ20004611A patent/CZ293010B6/cs not_active IP Right Cessation
- 1999-06-09 HU HU0102773A patent/HUP0102773A3/hu unknown
- 1999-06-09 NZ NZ508799A patent/NZ508799A/en unknown
- 1999-06-09 WO PCT/GB1999/001826 patent/WO1999065903A1/en not_active Application Discontinuation
- 1999-06-09 EP EP99957056A patent/EP1084122B1/en not_active Expired - Lifetime
- 1999-06-09 ID IDW20002580A patent/ID27593A/id unknown
- 1999-06-09 SK SK1896-2000A patent/SK18962000A3/sk unknown
- 1999-06-09 US US09/719,335 patent/US6410555B1/en not_active Expired - Fee Related
- 1999-06-09 BR BR9911110-1A patent/BR9911110A/pt not_active IP Right Cessation
- 1999-06-09 TR TR2000/03694T patent/TR200003694T2/xx unknown
- 1999-06-09 ES ES99957056T patent/ES2209524T3/es not_active Expired - Lifetime
- 1999-06-09 AU AU42800/99A patent/AU750470B2/en not_active Ceased
- 1999-06-10 MA MA25618A patent/MA26646A1/fr unknown
- 1999-06-10 AR ARP990102772A patent/AR018656A1/es not_active Application Discontinuation
- 1999-06-11 PE PE1999000519A patent/PE20000727A1/es not_active Application Discontinuation
- 1999-06-11 TW TW088109749A patent/TW495510B/zh active
- 1999-06-11 CO CO99036865A patent/CO5040081A1/es unknown
2000
- 2000-12-11 NO NO20006269A patent/NO20006269L/no not_active Application Discontinuation
- 2000-12-12 ZA ZA200007397A patent/ZA200007397B/xx unknown
2001
- 2001-01-08 BG BG105126A patent/BG105126A/xx unknown
2002
- 2002-05-23 US US10/154,997 patent/US6762192B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
DE69912278T2 (de)	2004-08-12
EP1084122A1 (en)	2001-03-21
AU750470B2 (en)	2002-07-18
HUP0102773A2 (hu)	2002-01-28
HUP0102773A3 (en)	2002-09-30
NO20006269L (no)	2001-02-07
NZ508799A (en)	2003-08-29
MA26646A1 (fr)	2004-12-20
US6762192B2 (en)	2004-07-13
AR018656A1 (es)	2001-11-28
EP1084122B1 (en)	2003-10-22
WO1999065903A1 (en)	1999-12-23
GB9812683D0 (en)	1998-08-12
NO20006269D0 (no)	2000-12-11
AU4280099A (en)	2000-01-05
US6410555B1 (en)	2002-06-25
IL140171A0 (en)	2002-02-10
KR20010052792A (ko)	2001-06-25
TW495510B (en)	2002-07-21
CO5040081A1 (es)	2001-05-29
ZA200007397B (en)	2002-02-27
PE20000727A1 (es)	2000-09-28
AP2000002009A0 (en)	2000-12-31
PL344791A1 (en)	2001-11-19
TR200003694T2 (tr)	2001-06-21
CA2334900A1 (en)	1999-12-23
BR9911110A (pt)	2001-10-30
DE69912278D1 (en)	2003-11-27
JP2002518390A (ja)	2002-06-25
ID27593A (id)	2001-04-12
CN1311789A (zh)	2001-09-05
BG105126A (en)	2001-11-30
CZ20004611A3 (en)	2001-06-13
ES2209524T3 (es)	2004-06-16
ATE252579T1 (de)	2003-11-15
EA200100033A1 (ru)	2001-06-25
CZ293010B6 (cs)	2004-01-14
US20020143029A1 (en)	2002-10-03

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SK126799A3 (en)	2000-05-16	Isoquinolyl-benzamide derivatives, process for their production, pharmaceutical composition containing them and their use
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