SI3983387T1 - Derivati sulfoniluree in njihove uporabe - Google Patents
Derivati sulfoniluree in njihove uporabeInfo
- Publication number
- SI3983387T1 SI3983387T1 SI202030459T SI202030459T SI3983387T1 SI 3983387 T1 SI3983387 T1 SI 3983387T1 SI 202030459 T SI202030459 T SI 202030459T SI 202030459 T SI202030459 T SI 202030459T SI 3983387 T1 SI3983387 T1 SI 3983387T1
- Authority
- SI
- Slovenia
- Prior art keywords
- sulfonylurea derivatives
- sulfonylurea
- derivatives
- Prior art date
Links
- YROXIXLRRCOBKF-UHFFFAOYSA-N sulfonylurea Chemical class OC(=N)N=S(=O)=O YROXIXLRRCOBKF-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/38—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/38—Nitrogen atoms
- C07D231/40—Acylated on said nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962860663P | 2019-06-12 | 2019-06-12 | |
| PCT/EP2020/066191 WO2020249667A1 (en) | 2019-06-12 | 2020-06-11 | Sulfonylurea derivatives and uses thereof |
| EP20733706.4A EP3983387B1 (en) | 2019-06-12 | 2020-06-11 | Sulfonylurea derivatives and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI3983387T1 true SI3983387T1 (sl) | 2024-09-30 |
Family
ID=71108563
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI202030459T SI3983387T1 (sl) | 2019-06-12 | 2020-06-11 | Derivati sulfoniluree in njihove uporabe |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US12054461B2 (sl) |
| EP (1) | EP3983387B1 (sl) |
| JP (1) | JP7682813B2 (sl) |
| CN (1) | CN114641466A (sl) |
| DK (1) | DK3983387T3 (sl) |
| ES (1) | ES2983661T3 (sl) |
| FI (1) | FI3983387T3 (sl) |
| HR (1) | HRP20240896T1 (sl) |
| HU (1) | HUE067378T2 (sl) |
| LT (1) | LT3983387T (sl) |
| PL (1) | PL3983387T3 (sl) |
| PT (1) | PT3983387T (sl) |
| RS (1) | RS65711B1 (sl) |
| SI (1) | SI3983387T1 (sl) |
| SM (1) | SMT202400291T1 (sl) |
| WO (1) | WO2020249667A1 (sl) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201721185D0 (en) | 2017-12-18 | 2018-01-31 | Nodthera Ltd | Sulphonyl urea derivatives |
| WO2020249667A1 (en) | 2019-06-12 | 2020-12-17 | NodThera Limited | Sulfonylurea derivatives and uses thereof |
| KR102802013B1 (ko) * | 2021-02-03 | 2025-05-07 | 환인제약 주식회사 | 알츠하이머병 치료를 위한 nlrp3 인플라마좀 소분자 억제제 |
Family Cites Families (61)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2110689A (en) | 1981-12-03 | 1983-06-22 | Sandoz Ltd | Herbicidal heterocyclic aminosulfonyl ureas and isoureas |
| CH649081A5 (de) | 1982-01-12 | 1985-04-30 | Ciba Geigy Ag | Triaza-verbindungen. |
| US4522811A (en) | 1982-07-08 | 1985-06-11 | Syntex (U.S.A.) Inc. | Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides |
| JPS60214785A (ja) * | 1984-03-27 | 1985-10-28 | Nissan Chem Ind Ltd | ピラゾ−ルスルホニルウレア誘導体、および植物生長調節剤または除草剤 |
| US5214206A (en) | 1990-11-07 | 1993-05-25 | Warner-Lambert Company | Aminosulfonyl urea acat inhibitors |
| JPH06510762A (ja) | 1991-08-19 | 1994-12-01 | イー・アイ・デュポン・ドゥ・ヌムール・アンド・カンパニー | アンジオテンシン２受容体遮断イミダゾリノン誘導体 |
| CZ36394A3 (en) | 1991-08-19 | 1994-07-13 | Du Pont | Substituted imidazilonone derivatives and pharmaceutical preparations based thereon |
| NZ247440A (en) | 1992-05-06 | 1995-04-27 | Squibb & Sons Inc | Phenyl sulphonamide derivatives, preparation and pharmaceutical compositions thereof |
| DE4217719A1 (de) | 1992-05-29 | 1993-12-02 | Bayer Ag | Zweifach heterocyclisch substituierte Sulfonylamino(thio)carbonylverbindungen |
| DE4302701A1 (de) | 1993-02-01 | 1994-08-04 | Bayer Ag | Arylaminosulfonylharnstoffe |
| DE4302702A1 (de) | 1993-02-01 | 1994-08-04 | Bayer Ag | Arylaminosulfonylharnstoffe |
| JP3355237B2 (ja) * | 1993-10-15 | 2002-12-09 | 呉羽化学工業株式会社 | Ｎ−（置換アミノ）ピロール誘導体、その製造方法及び除草剤 |
| JPH0827147A (ja) * | 1994-07-20 | 1996-01-30 | Kureha Chem Ind Co Ltd | Ｎ−（置換アミノ）イミド誘導体、その製造方法及び除草剤 |
| JPH09132574A (ja) | 1995-11-09 | 1997-05-20 | Nissan Chem Ind Ltd | フルオロプロピルチアゾリン誘導体の製造法 |
| US5763263A (en) | 1995-11-27 | 1998-06-09 | Dehlinger; Peter J. | Method and apparatus for producing position addressable combinatorial libraries |
| US6028201A (en) | 1996-01-30 | 2000-02-22 | Merck & Co., Inc. | Inhibitors of farnesyl-protein transferase |
| AU3440597A (en) | 1996-07-02 | 1998-01-21 | Novartis Ag | N-phenylimino heterocyclic derivatives and their use as herbicides |
| JPH1029990A (ja) | 1996-07-12 | 1998-02-03 | Kureha Chem Ind Co Ltd | １−（置換アミノ）イミダゾール誘導体、その製造方法及び除草剤 |
| DE19651037A1 (de) | 1996-12-09 | 1998-06-10 | Bayer Ag | Substituierte Thienyl(amino)sulfonyl(thio)harnstoffe |
| PL335052A1 (en) | 1997-01-29 | 2000-03-27 | Pfizer | Derivatives of sulphonylurea and their application in regulating activity of interleukin-1 |
| IT1290062B1 (it) | 1997-03-13 | 1998-10-19 | Isagro Ricerca Srl | Amminosolfoniluree ad attivita' erbicida |
| GB9909409D0 (en) | 1999-04-24 | 1999-06-23 | Zeneca Ltd | Chemical compounds |
| DE19937118A1 (de) | 1999-08-06 | 2001-02-08 | Bayer Ag | Substituierte Thienyl(amino)sulfonylharnstoffe |
| JP4112127B2 (ja) | 1999-08-31 | 2008-07-02 | 株式会社リコー | 感熱記録材料 |
| JP4556371B2 (ja) | 1999-09-30 | 2010-10-06 | 三菱化学株式会社 | アシルスルホンアミド誘導体 |
| US6593356B2 (en) | 1999-10-20 | 2003-07-15 | Bristol-Myers Squibb Pharma Company | Acylsemicarbazides as cyclin dependent kinase inhibitors useful as anti-cancer and anti-proliferative agents |
| EP1281399A3 (en) | 2001-08-01 | 2004-02-11 | Warner-Lambert Company | Dual inhibitors of wax ester and cholesteryl ester synthesis for inhibiting sebum production |
| WO2003029226A1 (en) | 2001-09-26 | 2003-04-10 | Basf Aktiengesellschaft | Heterocyclyl substituted phenoxyalkyl-, phenylthioalkyl-, phenylaminoalkyl- and phenylalkyl-sulfamoylcarboxamides |
| US7279576B2 (en) | 2002-12-31 | 2007-10-09 | Deciphera Pharmaceuticals, Llc | Anti-cancer medicaments |
| US7202257B2 (en) | 2003-12-24 | 2007-04-10 | Deciphera Pharmaceuticals, Llc | Anti-inflammatory medicaments |
| US7144911B2 (en) | 2002-12-31 | 2006-12-05 | Deciphera Pharmaceuticals Llc | Anti-inflammatory medicaments |
| US20070191336A1 (en) | 2003-12-24 | 2007-08-16 | Flynn Daniel L | Anti-inflammatory medicaments |
| EP1836173A4 (en) | 2004-12-23 | 2009-07-08 | Deciphera Pharmaceuticals Llc | ANTI-INFLAMMATORY DRUGS |
| AU2008345225A1 (en) | 2007-12-21 | 2009-07-09 | University Of Rochester | Method for altering the lifespan of eukaryotic organisms |
| WO2013119040A1 (en) | 2012-02-07 | 2013-08-15 | Kainos Medicine, Inc. | Compounds as inhibitors of diacylglycerol o-acyltransferase type 1 enzyme |
| CN103288750A (zh) | 2013-03-04 | 2013-09-11 | 盐城工学院 | 新型氨基磺酰脲类化合物 |
| US9410217B2 (en) | 2014-02-18 | 2016-08-09 | Renmatix, Inc. | Method of reducing a fermentation and/or enzyme inhibitor in a saccharide-containing composition |
| US10538487B2 (en) | 2015-02-16 | 2020-01-21 | The University Of Queensland | Sulfonylureas and related compounds and use of same |
| JP2019512009A (ja) | 2016-02-16 | 2019-05-09 | ザ・ユニバーシティ・オブ・クイーンズランド | スルホニルウレアおよび関連化合物ならびにこれらの利用 |
| WO2017189651A1 (en) | 2016-04-26 | 2017-11-02 | Enanta Pharmaceuticals, Inc. | Isoxazole derivatives as fxr agonists and methods of use thereof |
| WO2017189663A1 (en) | 2016-04-26 | 2017-11-02 | Enanta Pharmaceuticals, Inc. | Isoxazole derivatives as fxr agonists and methods of use thereof |
| WO2017189652A1 (en) | 2016-04-26 | 2017-11-02 | Enanta Pharmaceuticals, Inc. | Isoxazole derivatives as fxr agonists and methods of use thereof |
| WO2017201150A1 (en) | 2016-05-18 | 2017-11-23 | Enanta Pharmaceuticals, Inc. | Isoxazole analogs as fxr agonists and methods of use thereof |
| WO2017201152A1 (en) | 2016-05-18 | 2017-11-23 | Enanta Pharmaceuticals, Inc. | Isoxazole derivatives as fxr agonists and methods of use thereof |
| WO2017201155A1 (en) | 2016-05-18 | 2017-11-23 | Enanta Pharmaceuticals, Inc. | lSOXAZOLE DERIVATIVES AS FXR AGONISTS AND METHODS OF USE THEREOF |
| EP3272739A1 (en) | 2016-07-20 | 2018-01-24 | NodThera Limited | Sulfonyl urea derivatives and their use in the control of interleukin-1 activity |
| EP3658539B1 (en) | 2017-07-24 | 2024-02-21 | Novartis AG | Compounds and compositions for treating conditions associated with nlrp activity |
| WO2019034686A1 (en) * | 2017-08-15 | 2019-02-21 | Inflazome Limited | NOVEL CARBOXAMIDE SULFONAMIDE COMPOUNDS |
| EP3668862A1 (en) | 2017-08-15 | 2020-06-24 | Inflazome Limited | Novel sulfonamide carboxamide compounds |
| EP3668601A1 (en) | 2017-08-15 | 2020-06-24 | Inflazome Limited | Novel sulfonamide carboxamide compounds |
| WO2019034697A1 (en) | 2017-08-15 | 2019-02-21 | Inflazome Limited | NOVEL CARBOXAMIDE SULFONAMIDE COMPOUNDS |
| US11542255B2 (en) | 2017-08-15 | 2023-01-03 | Inflazome Limited | Sulfonylureas and sulfonylthioureas as NLRP3 inhibitors |
| US11926600B2 (en) | 2017-08-15 | 2024-03-12 | Inflazome Limited | Sulfonylureas and sulfonylthioureas as NLRP3 inhibitors |
| JP2020531453A (ja) | 2017-08-15 | 2020-11-05 | インフレイゾーム リミテッド | Ｎｌｒｐ３阻害剤としてのスルホニルウレアおよびスルホニルチオウレア |
| GB201721185D0 (en) | 2017-12-18 | 2018-01-31 | Nodthera Ltd | Sulphonyl urea derivatives |
| GB201902327D0 (en) * | 2019-02-20 | 2019-04-03 | Inflazome Ltd | Novel compounds |
| WO2020035464A1 (en) * | 2018-08-15 | 2020-02-20 | Inflazome Limited | Novel sulfonamideurea compounds |
| WO2020249664A1 (en) | 2019-06-12 | 2020-12-17 | NodThera Limited | Sulfonylurea derivatives and uses thereof |
| WO2020249669A1 (en) | 2019-06-12 | 2020-12-17 | NodThera Limited | Sulfonamide derivatives and uses thereof |
| WO2020249667A1 (en) | 2019-06-12 | 2020-12-17 | NodThera Limited | Sulfonylurea derivatives and uses thereof |
| EP4208459A1 (en) | 2020-09-04 | 2023-07-12 | Nodthera Limited | Sulphamoyl urea derivatives containing alkyl-oxacycloalkyl moiety and uses thereof |
-
2020
- 2020-06-11 WO PCT/EP2020/066191 patent/WO2020249667A1/en active Application Filing
- 2020-06-11 PL PL20733706.4T patent/PL3983387T3/pl unknown
- 2020-06-11 CN CN202080057162.2A patent/CN114641466A/zh active Pending
- 2020-06-11 PT PT207337064T patent/PT3983387T/pt unknown
- 2020-06-11 US US17/618,184 patent/US12054461B2/en active Active
- 2020-06-11 EP EP20733706.4A patent/EP3983387B1/en active Active
- 2020-06-11 JP JP2021573382A patent/JP7682813B2/ja active Active
- 2020-06-11 HU HUE20733706A patent/HUE067378T2/hu unknown
- 2020-06-11 SM SM20240291T patent/SMT202400291T1/it unknown
- 2020-06-11 RS RS20240765A patent/RS65711B1/sr unknown
- 2020-06-11 DK DK20733706.4T patent/DK3983387T3/da active
- 2020-06-11 ES ES20733706T patent/ES2983661T3/es active Active
- 2020-06-11 SI SI202030459T patent/SI3983387T1/sl unknown
- 2020-06-11 FI FIEP20733706.4T patent/FI3983387T3/fi active
- 2020-06-11 LT LTEPPCT/EP2020/066191T patent/LT3983387T/lt unknown
- 2020-06-11 HR HRP20240896TT patent/HRP20240896T1/hr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SMT202400291T1 (it) | 2024-09-16 |
| JP7682813B2 (ja) | 2025-05-26 |
| ES2983661T3 (es) | 2024-10-24 |
| HRP20240896T1 (hr) | 2024-10-11 |
| RS65711B1 (sr) | 2024-08-30 |
| HUE067378T2 (hu) | 2024-10-28 |
| FI3983387T3 (fi) | 2024-07-09 |
| JP2022535956A (ja) | 2022-08-10 |
| DK3983387T3 (da) | 2024-07-15 |
| WO2020249667A1 (en) | 2020-12-17 |
| CN114641466A (zh) | 2022-06-17 |
| PL3983387T3 (pl) | 2024-08-19 |
| EP3983387A1 (en) | 2022-04-20 |
| LT3983387T (lt) | 2024-07-25 |
| PT3983387T (pt) | 2024-07-10 |
| EP3983387B1 (en) | 2024-04-24 |
| US12054461B2 (en) | 2024-08-06 |
| US20220227715A1 (en) | 2022-07-21 |
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