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SI2988728T1 - Zmanjšanje velikosti delcev antimuskarinske spojine - Google Patents

Zmanjšanje velikosti delcev antimuskarinske spojine

Info

Publication number
SI2988728T1
SI2988728T1 SI201431365T SI201431365T SI2988728T1 SI 2988728 T1 SI2988728 T1 SI 2988728T1 SI 201431365 T SI201431365 T SI 201431365T SI 201431365 T SI201431365 T SI 201431365T SI 2988728 T1 SI2988728 T1 SI 2988728T1
Authority
SI
Slovenia
Prior art keywords
particle size
size reduction
antimuscarinic compound
antimuscarinic
compound
Prior art date
Application number
SI201431365T
Other languages
English (en)
Inventor
Irene Pasquali
Andrea Casazza
Mark Saunders
Elena Losi
Original Assignee
Chiesi Farm Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiesi Farm Spa filed Critical Chiesi Farm Spa
Publication of SI2988728T1 publication Critical patent/SI2988728T1/sl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Otolaryngology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SI201431365T 2013-04-26 2014-04-24 Zmanjšanje velikosti delcev antimuskarinske spojine SI2988728T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP13165483 2013-04-26
EP14724332.3A EP2988728B1 (en) 2013-04-26 2014-04-24 Particle size reduction of an antimuscarinic compound
PCT/EP2014/058295 WO2014173987A1 (en) 2013-04-26 2014-04-24 Particle size reduction of an antimuscarinic compound

Publications (1)

Publication Number Publication Date
SI2988728T1 true SI2988728T1 (sl) 2019-11-29

Family

ID=48190260

Family Applications (2)

Application Number Title Priority Date Filing Date
SI201431365T SI2988728T1 (sl) 2013-04-26 2014-04-24 Zmanjšanje velikosti delcev antimuskarinske spojine
SI201432023T SI3574895T1 (sl) 2013-04-26 2014-04-24 Zmanjšanje velikosti delcev antimuskarinske spojine

Family Applications After (1)

Application Number Title Priority Date Filing Date
SI201432023T SI3574895T1 (sl) 2013-04-26 2014-04-24 Zmanjšanje velikosti delcev antimuskarinske spojine

Country Status (28)

Country Link
US (2) US9393202B2 (sl)
EP (2) EP2988728B1 (sl)
JP (1) JP6449246B2 (sl)
KR (1) KR102198354B1 (sl)
CN (1) CN105120841B (sl)
AR (2) AR096087A1 (sl)
AU (1) AU2014259443B2 (sl)
BR (1) BR112015024626B1 (sl)
CA (1) CA2910314C (sl)
DK (2) DK3574895T3 (sl)
ES (2) ES2754255T3 (sl)
FI (1) FI3574895T3 (sl)
HK (1) HK1216302A1 (sl)
HR (2) HRP20230337T1 (sl)
HU (2) HUE062002T2 (sl)
IL (1) IL242209A (sl)
MX (1) MX365295B (sl)
MY (1) MY169127A (sl)
PH (1) PH12015502449B1 (sl)
PL (2) PL3574895T3 (sl)
PT (2) PT3574895T (sl)
RU (1) RU2667636C2 (sl)
SG (1) SG11201508760VA (sl)
SI (2) SI2988728T1 (sl)
TW (1) TWI630926B (sl)
UA (1) UA120418C2 (sl)
WO (1) WO2014173987A1 (sl)
ZA (1) ZA201507916B (sl)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9393202B2 (en) * 2013-04-26 2016-07-19 Chiesi Farmaceutici S.P.A Particle size reduction of an antimuscarinic compound
CN105338960B (zh) 2013-07-11 2019-06-04 奇斯药制品公司 用于吸入施用的包含抗胆碱能药、皮质类固醇和β-肾上腺素能药的干粉制剂
CN107106515A (zh) 2014-10-16 2017-08-29 梯瓦优质制药产品研发股份有限公司 可吸入的配制剂
JP6500522B2 (ja) * 2015-03-16 2019-04-17 セイコーエプソン株式会社 回路装置、物理量検出装置、電子機器及び移動体
JP6963548B2 (ja) 2015-11-16 2021-11-10 キエージ・フアルマチエウテイチ・エツセ・ピ・ア 抗コリン作用薬、コルチコステロイド及びβ−アドレナリン作用薬を含む乾燥粉末製剤を調製するための方法
MY198321A (en) 2015-11-16 2023-08-24 Chiesi Farm Spa A process for preparing a dry powder formulation comprising an anticholinergic, a corticosteroid and a beta-adrenergic
US9925168B2 (en) * 2016-01-22 2018-03-27 Chiesi Farmaceutici S.P.A. Preparation of micronized particles of an antimuscarinic compound by hydrodynamic cavitation
JP6323846B2 (ja) * 2016-04-07 2018-05-16 塩野義製薬株式会社 オピオイドを含有する乱用防止製剤
PT109445B (pt) * 2016-06-08 2018-11-06 Hovione Farm Sa Co-cristais farmacêuticos cristalinos de brometo de glicopirrónio com lactose
PL3490533T3 (pl) * 2016-07-29 2020-11-02 Inke, S.A. Sposób stabilizacji rozmiaru cząstek

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5399363A (en) * 1991-01-25 1995-03-21 Eastman Kodak Company Surface modified anticancer nanoparticles
WO1993025190A1 (en) * 1992-06-10 1993-12-23 Eastman Kodak Company Surface modified nsaid nanoparticles
GB0008660D0 (en) 2000-04-07 2000-05-31 Arakis Ltd The treatment of respiratory diseases
AU2003295631A1 (en) * 2002-11-18 2004-06-15 E.I. Du Pont De Nemours And Company Media milling using nonspherical grinding media
GB0321607D0 (en) * 2003-09-15 2003-10-15 Vectura Ltd Manufacture of pharmaceutical compositions
GB0409703D0 (en) * 2004-04-30 2004-06-02 Vectura Ltd Pharmaceutical compositions
GB0516549D0 (en) 2005-08-12 2005-09-21 Sulaiman Brian Milling system
GB0613161D0 (en) * 2006-06-30 2006-08-09 Novartis Ag Organic Compounds
AU2008334547B2 (en) * 2007-12-13 2011-06-30 Novartis Ag Organic compounds
WO2009074662A2 (en) 2007-12-13 2009-06-18 Novartis Ag Organic compounds
DE102008000482A1 (de) 2008-03-03 2009-09-10 Zf Friedrichshafen Ag Ölgekühltes Reibschaltelement
CN102149437B (zh) * 2008-07-18 2017-02-15 普罗索尼克斯有限公司 用于提高氟替卡松颗粒结晶度的方法
TWI707700B (zh) * 2009-05-29 2020-10-21 美商沛爾醫療股份有限公司 用於經由肺部遞送長效蕈毒鹼拮抗劑及長效β2腎上腺素受體激動劑之組成物，及相關方法及系統
JP2014504260A (ja) * 2010-10-15 2014-02-20 グラクソ グループ リミテッド 集合ナノ粒子状薬物製剤、その製造及び使用
US9393202B2 (en) * 2013-04-26 2016-07-19 Chiesi Farmaceutici S.P.A Particle size reduction of an antimuscarinic compound

Also Published As

Publication number Publication date
HUE062002T2 (hu) 2023-09-28
DK2988728T3 (da) 2019-11-04
FI3574895T3 (fi) 2023-05-25
US9393202B2 (en) 2016-07-19
MX365295B (es) 2019-05-29
MY169127A (en) 2019-02-18
JP2016521274A (ja) 2016-07-21
AU2014259443A1 (en) 2015-11-12
SG11201508760VA (en) 2015-11-27
UA120418C2 (uk) 2019-12-10
ES2943109T3 (es) 2023-06-09
EP2988728B1 (en) 2019-08-21
PH12015502449A1 (en) 2016-02-22
PT2988728T (pt) 2019-11-18
CA2910314A1 (en) 2014-10-30
PT3574895T (pt) 2023-04-28
SI3574895T1 (sl) 2023-05-31
ZA201507916B (en) 2017-05-31
TWI630926B (zh) 2018-08-01
AR096087A1 (es) 2015-12-02
KR20160002733A (ko) 2016-01-08
TW201521790A (zh) 2015-06-16
PH12015502449B1 (en) 2016-02-22
HK1216302A1 (zh) 2016-11-04
PL3574895T3 (pl) 2023-06-19
US20140322142A1 (en) 2014-10-30
RU2667636C2 (ru) 2018-09-21
JP6449246B2 (ja) 2019-01-09
KR102198354B1 (ko) 2021-01-06
IL242209A (en) 2017-12-31
BR112015024626A2 (pt) 2017-07-18
US9889094B2 (en) 2018-02-13
PL2988728T3 (pl) 2020-02-28
DK3574895T3 (da) 2023-05-01
CN105120841A (zh) 2015-12-02
US20160279066A1 (en) 2016-09-29
EP3574895A1 (en) 2019-12-04
AU2014259443B2 (en) 2019-01-03
MX2015014904A (es) 2016-03-07
EP3574895B1 (en) 2023-03-22
CA2910314C (en) 2022-03-01
HRP20230337T1 (hr) 2023-06-09
RU2015145521A (ru) 2017-05-16
HRP20191882T1 (hr) 2019-12-27
HUE046213T2 (hu) 2020-02-28
AR130026A2 (es) 2024-10-23
EP2988728A1 (en) 2016-03-02
WO2014173987A1 (en) 2014-10-30
ES2754255T3 (es) 2020-04-16
BR112015024626B1 (pt) 2022-11-01
CN105120841B (zh) 2019-04-30

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