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SI2827863T1 - Tekoči sestavek za uporabo v postopku zdravljenja odzivnih stanj na bendamustin v pacientih, pri katerih so potrebni zmanjšani vnosi za administracijo - Google Patents

Tekoči sestavek za uporabo v postopku zdravljenja odzivnih stanj na bendamustin v pacientih, pri katerih so potrebni zmanjšani vnosi za administracijo

Info

Publication number
SI2827863T1
SI2827863T1 SI201331394T SI201331394T SI2827863T1 SI 2827863 T1 SI2827863 T1 SI 2827863T1 SI 201331394 T SI201331394 T SI 201331394T SI 201331394 T SI201331394 T SI 201331394T SI 2827863 T1 SI2827863 T1 SI 2827863T1
Authority
SI
Slovenia
Prior art keywords
administration
liquid composition
patients requiring
requiring reduced
reduced volumes
Prior art date
Application number
SI201331394T
Other languages
English (en)
Inventor
Srikanth Sundaram
Scott L. Tarriff
Original Assignee
Eagle Pharmaceuticals, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=49212373&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SI2827863(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Eagle Pharmaceuticals, Inc. filed Critical Eagle Pharmaceuticals, Inc.
Publication of SI2827863T1 publication Critical patent/SI2827863T1/sl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/41841,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D235/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/12Radicals substituted by oxygen atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
SI201331394T 2012-03-20 2013-03-15 Tekoči sestavek za uporabo v postopku zdravljenja odzivnih stanj na bendamustin v pacientih, pri katerih so potrebni zmanjšani vnosi za administracijo SI2827863T1 (sl)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261613173P 2012-03-20 2012-03-20
US201261669889P 2012-07-10 2012-07-10
US201261678715P 2012-08-02 2012-08-02
EP13765020.6A EP2827863B1 (en) 2012-03-20 2013-03-15 Liquid composition for use in a method of treating bendamustine-responsive conditions in patients requiring reduced volumes for administration
PCT/US2013/032295 WO2013142359A1 (en) 2012-03-20 2013-03-15 Method of treating bendamustine-responsive conditions in patients requiring reduced volumes for administration

Publications (1)

Publication Number Publication Date
SI2827863T1 true SI2827863T1 (sl) 2019-06-28

Family

ID=49212373

Family Applications (2)

Application Number Title Priority Date Filing Date
SI201332039T SI3533447T1 (sl) 2012-03-20 2013-03-15 Tekoči sestavki bendamustina za uporabo v postopku zdravljenja na bendamustin odzivnih stanj pri bolnikih,pri katerih so potrebni zmanjšani volumni za dajanje
SI201331394T SI2827863T1 (sl) 2012-03-20 2013-03-15 Tekoči sestavek za uporabo v postopku zdravljenja odzivnih stanj na bendamustin v pacientih, pri katerih so potrebni zmanjšani vnosi za administracijo

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SI201332039T SI3533447T1 (sl) 2012-03-20 2013-03-15 Tekoči sestavki bendamustina za uporabo v postopku zdravljenja na bendamustin odzivnih stanj pri bolnikih,pri katerih so potrebni zmanjšani volumni za dajanje

Country Status (17)

Country Link
US (3) US9000021B2 (sl)
EP (3) EP2827863B1 (sl)
JP (6) JP6224064B2 (sl)
CN (2) CN104271135B (sl)
CA (1) CA2867343C (sl)
DK (2) DK2827863T3 (sl)
ES (2) ES2943668T3 (sl)
FI (1) FI3533447T3 (sl)
HK (1) HK1243346A1 (sl)
HR (2) HRP20230276T1 (sl)
HU (2) HUE062230T2 (sl)
LT (1) LT2827863T (sl)
PL (2) PL3533447T3 (sl)
PT (2) PT3533447T (sl)
RS (2) RS64137B1 (sl)
SI (2) SI3533447T1 (sl)
WO (1) WO2013142359A1 (sl)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL2528602T5 (pl) 2010-01-28 2020-09-07 Eagle Pharmaceuticals, Inc. Preparaty bendamustyny
DK2827862T3 (da) * 2012-03-20 2024-02-12 Eagle Pharmaceuticals Inc Formuleringer af bendamustin
WO2013142359A1 (en) 2012-03-20 2013-09-26 Eagle Pharmaceuticals, Inc. Method of treating bendamustine-responsive conditions in patients requiring reduced volumes for administration
US20230241218A1 (en) * 2012-07-10 2023-08-03 Eagle Pharmaceuticals, Inc. Formulations of bendamustine
US11826466B2 (en) 2016-08-31 2023-11-28 Navinta, Llc Bendamustine solution formulations
US10905677B2 (en) 2016-08-31 2021-02-02 Navinta, Llc Bendamustine solution formulations
WO2020035806A1 (en) 2018-08-17 2020-02-20 Hospira Australia Pty Ltd Liquid bendamustine pharmaceutical compositions
US11730815B2 (en) * 2018-11-26 2023-08-22 Good Health, Llc Stable liquid pharmaceutical compositions comprising bendamustine
JP7235288B2 (ja) * 2019-01-07 2023-03-08 コーアイセイ株式会社 ベンダムスチンの液体製剤
CN110123747A (zh) * 2019-04-26 2019-08-16 嘉兴市爵拓科技有限公司 苯达莫司汀的制剂
JPWO2021014957A1 (sl) * 2019-07-22 2021-01-28
JPWO2021161876A1 (sl) * 2020-02-10 2021-08-19
US20240148696A1 (en) 2022-10-25 2024-05-09 Softkemo Pharma Inc. Lyophilized bendamustine-cyclodextrin composition

Family Cites Families (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE159289C (sl) 1903-10-08 1905-03-16
US4071620A (en) 1977-01-10 1978-01-31 American Home Products Corporation Stabilization of oxygen sensitive dose forms
DD159289A1 (de) 1981-06-01 1983-03-02 Uwe Olthoff Verfahren zur herstellung stabiler injektionsloesungen von n-lostverbindungen
DE3446873A1 (de) 1984-12-21 1986-07-10 Merckle Gmbh Fluessige diclofenac-zubereitungen
US5223515A (en) 1988-08-18 1993-06-29 Takeda Chemical Industries, Ltd. Injectable solution containing a pyridyl methylsulfinylbenzimidazole
CA2181241C (en) 1994-01-24 2000-04-25 Dadi Jamshed Dhabhar Process for solubilizing difficultly soluble pharmaceutical actives
ATE526022T1 (de) 1998-04-20 2011-10-15 Eisai R&D Man Co Ltd Stabilisierte zusammenstellungen die benzimidazole enthalten
AU2001211213A1 (en) 2000-10-20 2002-04-29 Galephar M/F Stable oral formulation containing benzimidazole derivative
AR040693A1 (es) 2002-07-30 2005-04-13 Wyeth Corp Formulaciones parenterales
US20060035945A1 (en) 2003-05-30 2006-02-16 Giorgio Attardo Triheterocyclic compounds, compositions, and methods for treating cancer or viral diseases
SE0401842D0 (sv) * 2004-07-12 2004-07-12 Dizlin Medical Design Ab Infusion and injection solution of levodopa
JP2008519047A (ja) 2004-11-05 2008-06-05 セフアロン・インコーポレーテツド 癌処置
US8436190B2 (en) 2005-01-14 2013-05-07 Cephalon, Inc. Bendamustine pharmaceutical compositions
WO2007026771A1 (ja) * 2005-08-31 2007-03-08 Ono Pharmaceutical Co., Ltd. 点滴用注射剤
AU2007285215A1 (en) 2006-08-14 2008-02-21 Eisai R & D Management Co., Ltd. Stable lyophilized preparation
US8277807B2 (en) 2006-10-12 2012-10-02 Astex Therapeutics Limited Pharmaceutical combinations
US8414909B2 (en) 2006-11-20 2013-04-09 Lutonix, Inc. Drug releasing coatings for medical devices
DE102007003184A1 (de) 2007-01-22 2008-07-24 Orlowski, Michael, Dr. Verfahren zur Beladung von strukturierten Oberflächen
US20090082416A1 (en) 2007-09-25 2009-03-26 Protia, Llc Deuterium-enriched bendamustine
AR072777A1 (es) 2008-03-26 2010-09-22 Cephalon Inc Formas solidas de clorhidrato de bendamustina
EP2889029A1 (en) * 2008-09-25 2015-07-01 Cephalon, Inc. Liquid formulations of bendamustine
KR20110110293A (ko) 2009-01-15 2011-10-06 세파론, 인코포레이티드 벤다무스틴 유리 염기의 신규 형태
RU2591804C2 (ru) 2009-02-25 2016-07-20 Супратек Фарма, Инк. Композиции бендамустина и циклополисахарида
US20100273730A1 (en) * 2009-04-27 2010-10-28 Innopharmax, Inc. Self-emulsifying pharmaceutical compositions of hydrophilic drugs and preparation thereof
EP2424506A1 (en) 2009-04-28 2012-03-07 Cephalon, Inc. Oral formulations of bendamustine
WO2010148288A2 (en) 2009-06-19 2010-12-23 Lyotropic Therapeutics, Inc. Pharmaceutical formulations with low aqueous levels of free unbound drug
CN101584668A (zh) * 2009-06-19 2009-11-25 江苏奥赛康药业有限公司 盐酸苯达莫司汀冻干粉针剂
US8389558B2 (en) 2009-07-20 2013-03-05 Supratek Pharma Inc. Bendamustine amphiphilic anionic compositions
US20110015245A1 (en) 2009-07-20 2011-01-20 Valery Alakhov Bendamustine amphiphilic cationic compositions
US7772274B1 (en) 2009-10-19 2010-08-10 Scidose, Llc Docetaxel formulations with lipoic acid
PL2528602T5 (pl) * 2010-01-28 2020-09-07 Eagle Pharmaceuticals, Inc. Preparaty bendamustyny
ES2593256T3 (es) 2010-05-21 2016-12-07 Infinity Pharmaceuticals, Inc. Compuestos químicos, composiciones y métodos para las modulaciones de cinasas
CA2804855A1 (en) 2010-07-28 2012-02-02 Eagle Pharmaceuticals, Inc. Pharmaceutical compositions containing pemetrexed having extended storage stability
AU2012347972B2 (en) 2011-12-05 2018-05-10 X-Body, Inc. PDGF receptor beta binding polypeptides
US20130210878A1 (en) * 2012-01-24 2013-08-15 Innopharma, Inc. Bendamustine compositions and methods therefore
WO2013123227A1 (en) 2012-02-14 2013-08-22 Eagle Pharmaceuticals, Inc. Formulations of bendamustine
WO2013142359A1 (en) 2012-03-20 2013-09-26 Eagle Pharmaceuticals, Inc. Method of treating bendamustine-responsive conditions in patients requiring reduced volumes for administration
DK2827862T3 (da) 2012-03-20 2024-02-12 Eagle Pharmaceuticals Inc Formuleringer af bendamustin

Also Published As

Publication number Publication date
DK3533447T3 (da) 2023-04-24
FI3533447T3 (fi) 2023-05-04
CN107157988A (zh) 2017-09-15
JP2020143143A (ja) 2020-09-10
HUE062230T2 (hu) 2023-10-28
RS64137B1 (sr) 2023-05-31
SI3533447T1 (sl) 2023-06-30
JP6381761B2 (ja) 2018-08-29
WO2013142359A1 (en) 2013-09-26
CN104271135A (zh) 2015-01-07
PT2827863T (pt) 2019-05-13
US20150343061A1 (en) 2015-12-03
PL2827863T3 (pl) 2019-07-31
HK1243346A1 (zh) 2018-07-13
EP2827863B1 (en) 2019-01-16
US9000021B2 (en) 2015-04-07
JP2022028813A (ja) 2022-02-16
EP4218756A1 (en) 2023-08-02
ES2718902T3 (es) 2019-07-05
PL3533447T3 (pl) 2023-07-17
EP3533447A1 (en) 2019-09-04
PT3533447T (pt) 2023-05-17
LT2827863T (lt) 2019-06-10
HUE044233T2 (hu) 2019-10-28
US9579384B2 (en) 2017-02-28
DK2827863T3 (en) 2019-04-23
JP6224064B2 (ja) 2017-11-01
ES2943668T3 (es) 2023-06-15
CA2867343C (en) 2020-08-11
JP2015510940A (ja) 2015-04-13
CN104271135B (zh) 2017-05-17
US20150080444A1 (en) 2015-03-19
RS58744B1 (sr) 2019-06-28
HRP20190693T1 (hr) 2019-10-04
EP2827863A1 (en) 2015-01-28
HRP20230276T1 (hr) 2023-04-28
EP2827863A4 (en) 2015-11-18
CA2867343A1 (en) 2013-09-26
JP2018197248A (ja) 2018-12-13
EP3533447B1 (en) 2023-03-15
JP2018048153A (ja) 2018-03-29
US20130253026A1 (en) 2013-09-26
JP2024037915A (ja) 2024-03-19
JP6738376B2 (ja) 2020-08-12

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