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DK2827862T3 - Formuleringer af bendamustin - Google Patents

Formuleringer af bendamustin Download PDF

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Publication number
DK2827862T3
DK2827862T3 DK13764989.3T DK13764989T DK2827862T3 DK 2827862 T3 DK2827862 T3 DK 2827862T3 DK 13764989 T DK13764989 T DK 13764989T DK 2827862 T3 DK2827862 T3 DK 2827862T3
Authority
DK
Denmark
Prior art keywords
bendamustine
formulations
Prior art date
Application number
DK13764989.3T
Other languages
English (en)
Inventor
Srikanth Sundaram
Original Assignee
Eagle Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=49212372&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK2827862(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Eagle Pharmaceuticals Inc filed Critical Eagle Pharmaceuticals Inc
Application granted granted Critical
Publication of DK2827862T3 publication Critical patent/DK2827862T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/41841,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
DK13764989.3T 2012-03-20 2013-03-15 Formuleringer af bendamustin DK2827862T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261613173P 2012-03-20 2012-03-20
US201261669889P 2012-07-10 2012-07-10
PCT/US2013/032289 WO2013142358A1 (en) 2012-03-20 2013-03-15 Formulations of bendamustine

Publications (1)

Publication Number Publication Date
DK2827862T3 true DK2827862T3 (da) 2024-02-12

Family

ID=49212372

Family Applications (1)

Application Number Title Priority Date Filing Date
DK13764989.3T DK2827862T3 (da) 2012-03-20 2013-03-15 Formuleringer af bendamustin

Country Status (15)

Country Link
US (20) US9034908B2 (da)
EP (2) EP4360621A3 (da)
JP (8) JP6250628B2 (da)
CN (1) CN104302291A (da)
CA (1) CA2867295C (da)
DK (1) DK2827862T3 (da)
ES (1) ES2972227T3 (da)
FI (1) FI2827862T3 (da)
HR (1) HRP20240056T1 (da)
HU (1) HUE064884T2 (da)
PL (1) PL2827862T3 (da)
PT (1) PT2827862T (da)
RS (1) RS65177B1 (da)
SI (1) SI2827862T1 (da)
WO (1) WO2013142358A1 (da)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011094565A1 (en) 2010-01-28 2011-08-04 Eagle Pharmaceuticals, Inc. Formulations of bendamustine
US20230241218A1 (en) * 2012-07-10 2023-08-03 Eagle Pharmaceuticals, Inc. Formulations of bendamustine
PL3533447T3 (pl) 2012-03-20 2023-07-17 Eagle Pharmaceuticals, Inc. Ciekłe kompozycje bendamustyny do zastosowania w sposobie leczenia stanów reagujących na bendamustynę u pacjentów wymagających obniżonych objętości do podawania
JP6250628B2 (ja) * 2012-03-20 2017-12-20 イーグル・ファーマシューティカルズ・インコーポレーテッド ベンダムスチンの製剤
CA2922099C (en) 2013-08-27 2022-11-29 Vasilios VOUDOURIS Bendamustine pharmaceutical compositions
CN105726472B (zh) * 2016-03-25 2019-12-13 南京康玻斯医药科技有限公司 苯达莫司汀药剂组合物及应用
US11826466B2 (en) 2016-08-31 2023-11-28 Navinta, Llc Bendamustine solution formulations
US10905677B2 (en) 2016-08-31 2021-02-02 Navinta, Llc Bendamustine solution formulations
US12246007B2 (en) 2018-08-17 2025-03-11 Hospira Australia Pty Ltd Liquid bendamustine pharmaceutical compositions
US11730815B2 (en) 2018-11-26 2023-08-22 Good Health, Llc Stable liquid pharmaceutical compositions comprising bendamustine
WO2020236150A1 (en) * 2019-05-20 2020-11-26 MAIA Pharmaceuticals, Inc. Ready-to-use bivalirudin compositions
US11992514B2 (en) 2019-05-20 2024-05-28 MAIA Pharmaceuticals, Inc. Ready-to-use bivalirudin compositions
EP4134068A4 (en) * 2020-04-09 2024-02-07 Bika Biotechnology (Guangzhou) Co., Ltd. Bendamustine composition and use thereof
US11707450B1 (en) 2022-03-03 2023-07-25 Slayback Pharma Llc Stable pharmaceutical compositions of bendamustine

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DD159289A1 (de) 1981-06-01 1983-03-02 Uwe Olthoff Verfahren zur herstellung stabiler injektionsloesungen von n-lostverbindungen
DE3446873A1 (de) 1984-12-21 1986-07-10 Merckle Gmbh Fluessige diclofenac-zubereitungen
US4879286A (en) 1987-01-28 1989-11-07 Lyphomed, Inc. Cyclophosphamide
US5223515A (en) 1988-08-18 1993-06-29 Takeda Chemical Industries, Ltd. Injectable solution containing a pyridyl methylsulfinylbenzimidazole
MX9602955A (es) 1994-01-24 1997-06-28 Procter & Gamble Procedimiento para solubizar activos farmaceuticos dificilmente solubles.
CN1261803A (zh) 1997-07-01 2000-08-02 埃瑟若詹尼克斯公司 抗氧化剂增强对细胞过度增生性疾病的治疗
KR100627614B1 (ko) 1998-04-20 2006-09-25 에자이 가부시키가이샤 안정화된 벤즈이미다졸계 화합물 함유 조성물로 이루어지는 의약제제
AUPQ849900A0 (en) 2000-06-30 2000-07-27 Dbl Australia Pty Ltd. Injectable composition
AU2001211213A1 (en) 2000-10-20 2002-04-29 Galephar M/F Stable oral formulation containing benzimidazole derivative
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US20060035945A1 (en) 2003-05-30 2006-02-16 Giorgio Attardo Triheterocyclic compounds, compositions, and methods for treating cancer or viral diseases
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US8436190B2 (en) 2005-01-14 2013-05-07 Cephalon, Inc. Bendamustine pharmaceutical compositions
AU2006235183B2 (en) 2005-04-08 2011-02-10 Amylin Pharmaceuticals, Llc Pharmaceutical formulations comprising incretin peptide and aprotic polar solvent
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US8414909B2 (en) * 2006-11-20 2013-04-09 Lutonix, Inc. Drug releasing coatings for medical devices
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AR072777A1 (es) 2008-03-26 2010-09-22 Cephalon Inc Formas solidas de clorhidrato de bendamustina
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WO2011103150A2 (en) * 2010-02-18 2011-08-25 Cephalon, Inc. Lyophilized preparations of bendamustine
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WO2013123227A1 (en) * 2012-02-14 2013-08-22 Eagle Pharmaceuticals, Inc. Formulations of bendamustine
PL3533447T3 (pl) * 2012-03-20 2023-07-17 Eagle Pharmaceuticals, Inc. Ciekłe kompozycje bendamustyny do zastosowania w sposobie leczenia stanów reagujących na bendamustynę u pacjentów wymagających obniżonych objętości do podawania
JP6250628B2 (ja) * 2012-03-20 2017-12-20 イーグル・ファーマシューティカルズ・インコーポレーテッド ベンダムスチンの製剤
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Also Published As

Publication number Publication date
US20230285563A1 (en) 2023-09-14
US20160000759A1 (en) 2016-01-07
JP7133070B2 (ja) 2022-09-07
US9144568B1 (en) 2015-09-29
US9572888B2 (en) 2017-02-21
US20260000767A1 (en) 2026-01-01
SI2827862T1 (sl) 2024-03-29
EP2827862A4 (en) 2015-11-18
JP2022130630A (ja) 2022-09-06
FI2827862T3 (fi) 2024-02-13
JP6570601B2 (ja) 2019-09-04
US9597397B2 (en) 2017-03-21
ES2972227T3 (es) 2024-06-11
PL2827862T3 (pl) 2024-05-06
US20130253025A1 (en) 2013-09-26
US9597399B2 (en) 2017-03-21
US20220323584A1 (en) 2022-10-13
EP4360621A2 (en) 2024-05-01
CN104302291A (zh) 2015-01-21
US20220265829A1 (en) 2022-08-25
US20200282057A1 (en) 2020-09-10
US10052385B2 (en) 2018-08-21
US20160296622A1 (en) 2016-10-13
PT2827862T (pt) 2024-03-06
US20160144035A1 (en) 2016-05-26
RS65177B1 (sr) 2024-03-29
EP2827862A1 (en) 2015-01-28
US9597398B2 (en) 2017-03-21
US20190192659A1 (en) 2019-06-27
WO2013142358A1 (en) 2013-09-26
US20180185488A1 (en) 2018-07-05
US20140275196A1 (en) 2014-09-18
HUE064884T2 (hu) 2024-04-28
JP2015510939A (ja) 2015-04-13
JP6250628B2 (ja) 2017-12-20
US9034908B2 (en) 2015-05-19
US20150250766A1 (en) 2015-09-10
US20140094496A1 (en) 2014-04-03
JP2022130629A (ja) 2022-09-06
US20180000938A1 (en) 2018-01-04
JP2021178846A (ja) 2021-11-18
US20160144034A1 (en) 2016-05-26
EP4360621A3 (en) 2024-05-22
CA2867295A1 (en) 2013-09-26
US9572887B2 (en) 2017-02-21
HRP20240056T1 (hr) 2024-03-29
JP2018070624A (ja) 2018-05-10
JP2022141895A (ja) 2022-09-29
EP2827862B1 (en) 2023-12-27
US20200368355A1 (en) 2020-11-26
US20180369383A1 (en) 2018-12-27
US20160296621A1 (en) 2016-10-13
US20210106686A1 (en) 2021-04-15
JP2024045290A (ja) 2024-04-02
CA2867295C (en) 2020-08-11
JP2019214592A (ja) 2019-12-19

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