SI2748146T1 - Kristalinična oblika natrijeve soli 4-terc-butil-N-(4-kloro-2-(1-oksi-piridin-4-karbonil)-fenil)-benzen sulfonamid - Google Patents
Kristalinična oblika natrijeve soli 4-terc-butil-N-(4-kloro-2-(1-oksi-piridin-4-karbonil)-fenil)-benzen sulfonamidInfo
- Publication number
- SI2748146T1 SI2748146T1 SI201230957T SI201230957T SI2748146T1 SI 2748146 T1 SI2748146 T1 SI 2748146T1 SI 201230957 T SI201230957 T SI 201230957T SI 201230957 T SI201230957 T SI 201230957T SI 2748146 T1 SI2748146 T1 SI 2748146T1
- Authority
- SI
- Slovenia
- Prior art keywords
- oxy
- carbonyl
- pyridine
- chloro
- tert
- Prior art date
Links
- 159000000000 sodium salts Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4409—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 4, e.g. isoniazid, iproniazid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Rheumatology (AREA)
- Dermatology (AREA)
- Pain & Pain Management (AREA)
- Transplantation (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161510832P | 2011-07-22 | 2011-07-22 | |
| PCT/US2012/047559 WO2013016174A1 (en) | 2011-07-22 | 2012-07-20 | A crystalline form of the sodium salt of 4-tert-butyl-n-[4-chloro-2-(1-oxy-pyridine-4-carbonyl)-phenyl]-benzene sulfonamide |
| EP12741219.5A EP2748146B1 (en) | 2011-07-22 | 2012-07-20 | A crystalline form of the sodium salt of 4-tert-butyl-n-[4-chloro-2-(1-oxy-pyridine-4-carbonyl)-phenyl]-benzene sulfonamide |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI2748146T1 true SI2748146T1 (sl) | 2017-10-30 |
Family
ID=46599010
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI201230957T SI2748146T1 (sl) | 2011-07-22 | 2012-07-20 | Kristalinična oblika natrijeve soli 4-terc-butil-N-(4-kloro-2-(1-oksi-piridin-4-karbonil)-fenil)-benzen sulfonamid |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US9133124B2 (sl) |
| EP (1) | EP2748146B1 (sl) |
| JP (1) | JP6122003B2 (sl) |
| CN (1) | CN103842343B (sl) |
| AU (1) | AU2012287160B2 (sl) |
| BR (1) | BR112014001299B1 (sl) |
| CA (1) | CA2841967C (sl) |
| DK (1) | DK2748146T3 (sl) |
| ES (1) | ES2625286T3 (sl) |
| HR (1) | HRP20170745T1 (sl) |
| HU (1) | HUE032747T2 (sl) |
| IL (1) | IL230468B (sl) |
| MX (1) | MX350269B (sl) |
| PL (1) | PL2748146T3 (sl) |
| PT (1) | PT2748146T (sl) |
| RS (1) | RS56023B1 (sl) |
| RU (1) | RU2607515C2 (sl) |
| SI (1) | SI2748146T1 (sl) |
| WO (1) | WO2013016174A1 (sl) |
| ZA (1) | ZA201400474B (sl) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL316296A (en) * | 2011-07-22 | 2024-12-01 | Chemocentryx Inc | Polymorphic forms of sodium salt of 4-tert-butyl-N-[4-chloro-2-(1-oxypyridine-4-carbonyl)-phenyl]-benzenesulfonamide |
| CN103813793A (zh) * | 2011-07-22 | 2014-05-21 | 葛兰素史克知识产权开发有限公司 | 4-叔丁基-n-[4-氯-2-(1-氧基-吡啶-4-羰基)-苯基]-苯磺酰胺钠盐的多晶型 |
| EP3141235A1 (en) * | 2012-12-06 | 2017-03-15 | IP Gesellschaft für Management mbH | N-(6-((2r,3s)-3,4-dihydroxybutan-2-yloxy)-2-(4-fluorobenzylthio)pyrimidin-4-yl)-3-methylazetidine-l -sulfonamide |
| WO2014159050A1 (en) * | 2013-03-14 | 2014-10-02 | United Therapeutics Corporation | Solid forms of treprostinil |
| SG11201702793XA (en) | 2014-10-06 | 2017-05-30 | Chemocentryx Inc | Combination therapy of inhibitors of c-c chemokine receptor type 9 (ccr9) and anti-alha4beta7 integrin blocking antibodies |
| US10792360B1 (en) | 2019-11-21 | 2020-10-06 | Chemocentryx, Inc. | Compositions and methods for treating inflammatory bowel disease using CCR9 inhibitor and anti-TNF-alpha blocking antibodies |
| TW202203916A (zh) | 2020-03-31 | 2022-02-01 | 美商卡默森屈有限公司 | 使用ｃｃｒ９抑制劑及抗ｉｌ—２３阻斷抗體治療發炎性腸道疾病的組成物及方法 |
Family Cites Families (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4826689A (en) | 1984-05-21 | 1989-05-02 | University Of Rochester | Method for making uniformly sized particles from water-insoluble organic compounds |
| FR2634376B1 (fr) | 1988-07-21 | 1992-04-17 | Farmalyoc | Nouvelle forme unitaire, solide et poreuse comprenant des microparticules et/ou des nanoparticules, ainsi que sa preparation |
| IT1227626B (it) | 1988-11-28 | 1991-04-23 | Vectorpharma Int | Farmaci supportati aventi velocita' di dissoluzione aumentata e procedimento per la loro preparazione |
| IT1243390B (it) | 1990-11-22 | 1994-06-10 | Vectorpharma Int | Composizioni farmaceutiche in forma di particelle atte al rilascio controllato di sostanze farmacologicamente attive e procedimento per la loro preparazione. |
| US5552160A (en) | 1991-01-25 | 1996-09-03 | Nanosystems L.L.C. | Surface modified NSAID nanoparticles |
| US5145684A (en) | 1991-01-25 | 1992-09-08 | Sterling Drug Inc. | Surface modified drug nanoparticles |
| JP4439590B2 (ja) | 1992-06-10 | 2010-03-24 | エラン ファーマ インターナショナル，リミティド | 表面改質ｎｓａｉｄナノ粒子 |
| AU660852B2 (en) | 1992-11-25 | 1995-07-06 | Elan Pharma International Limited | Method of grinding pharmaceutical substances |
| US5346702A (en) | 1992-12-04 | 1994-09-13 | Sterling Winthrop Inc. | Use of non-ionic cloud point modifiers to minimize nanoparticle aggregation during sterilization |
| US5298262A (en) | 1992-12-04 | 1994-03-29 | Sterling Winthrop Inc. | Use of ionic cloud point modifiers to prevent particle aggregation during sterilization |
| US5302401A (en) | 1992-12-09 | 1994-04-12 | Sterling Winthrop Inc. | Method to reduce particle size growth during lyophilization |
| US5340564A (en) | 1992-12-10 | 1994-08-23 | Sterling Winthrop Inc. | Formulations comprising olin 10-G to prevent particle aggregation and increase stability |
| US5336507A (en) | 1992-12-11 | 1994-08-09 | Sterling Winthrop Inc. | Use of charged phospholipids to reduce nanoparticle aggregation |
| US5429824A (en) | 1992-12-15 | 1995-07-04 | Eastman Kodak Company | Use of tyloxapole as a nanoparticle stabilizer and dispersant |
| US5352459A (en) | 1992-12-16 | 1994-10-04 | Sterling Winthrop Inc. | Use of purified surface modifiers to prevent particle aggregation during sterilization |
| US5587143A (en) | 1994-06-28 | 1996-12-24 | Nanosystems L.L.C. | Butylene oxide-ethylene oxide block copolymer surfactants as stabilizer coatings for nanoparticle compositions |
| US5585108A (en) | 1994-12-30 | 1996-12-17 | Nanosystems L.L.C. | Formulations of oral gastrointestinal therapeutic agents in combination with pharmaceutically acceptable clays |
| US5665331A (en) | 1995-01-10 | 1997-09-09 | Nanosystems L.L.C. | Co-microprecipitation of nanoparticulate pharmaceutical agents with crystal growth modifiers |
| US5662883A (en) | 1995-01-10 | 1997-09-02 | Nanosystems L.L.C. | Microprecipitation of micro-nanoparticulate pharmaceutical agents |
| US5560932A (en) | 1995-01-10 | 1996-10-01 | Nano Systems L.L.C. | Microprecipitation of nanoparticulate pharmaceutical agents |
| US5569448A (en) | 1995-01-24 | 1996-10-29 | Nano Systems L.L.C. | Sulfated nonionic block copolymer surfactants as stabilizer coatings for nanoparticle compositions |
| US5571536A (en) | 1995-02-06 | 1996-11-05 | Nano Systems L.L.C. | Formulations of compounds as nanoparticulate dispersions in digestible oils or fatty acids |
| US5560931A (en) | 1995-02-14 | 1996-10-01 | Nawosystems L.L.C. | Formulations of compounds as nanoparticulate dispersions in digestible oils or fatty acids |
| US5503723A (en) | 1995-02-08 | 1996-04-02 | Eastman Kodak Company | Isolation of ultra small particles |
| US5534270A (en) | 1995-02-09 | 1996-07-09 | Nanosystems Llc | Method of preparing stable drug nanoparticles |
| US5622938A (en) | 1995-02-09 | 1997-04-22 | Nano Systems L.L.C. | Sugar base surfactant for nanocrystals |
| US5518738A (en) | 1995-02-09 | 1996-05-21 | Nanosystem L.L.C. | Nanoparticulate nsaid compositions |
| US5591456A (en) | 1995-02-10 | 1997-01-07 | Nanosystems L.L.C. | Milled naproxen with hydroxypropyl cellulose as a dispersion stabilizer |
| US5573783A (en) | 1995-02-13 | 1996-11-12 | Nano Systems L.L.C. | Redispersible nanoparticulate film matrices with protective overcoats |
| US5510118A (en) | 1995-02-14 | 1996-04-23 | Nanosystems Llc | Process for preparing therapeutic compositions containing nanoparticles |
| US5580579A (en) | 1995-02-15 | 1996-12-03 | Nano Systems L.L.C. | Site-specific adhesion within the GI tract using nanoparticles stabilized by high molecular weight, linear poly (ethylene oxide) polymers |
| US5747001A (en) | 1995-02-24 | 1998-05-05 | Nanosystems, L.L.C. | Aerosols containing beclomethazone nanoparticle dispersions |
| US5718919A (en) | 1995-02-24 | 1998-02-17 | Nanosystems L.L.C. | Nanoparticles containing the R(-)enantiomer of ibuprofen |
| US5565188A (en) | 1995-02-24 | 1996-10-15 | Nanosystems L.L.C. | Polyalkylene block copolymers as surface modifiers for nanoparticles |
| WO1998035666A1 (en) | 1997-02-13 | 1998-08-20 | Nanosystems Llc | Formulations of nanoparticle naproxen tablets |
| CA2784937A1 (en) * | 2002-05-24 | 2003-12-04 | Millennium Pharmaceuticals, Inc. | Ccr9 inhibitors and methods of use thereof |
| KR100866456B1 (ko) | 2002-11-18 | 2008-10-31 | 케모센트릭스 | 아릴 술폰아마이드 |
| EP1722789A2 (en) * | 2004-03-08 | 2006-11-22 | Amgen Inc. | Therapeutic modulation of ppar (gamma) activity |
| WO2005113513A2 (en) * | 2004-05-12 | 2005-12-01 | Chemocentryx | Aryl sulfonamides |
| US8519135B2 (en) * | 2006-07-14 | 2013-08-27 | Chemocentryx, Inc. | Heteroaryl sulfonamides and CCR2/CCR9 |
| EA015710B1 (ru) * | 2006-07-14 | 2011-10-31 | Хемоцентрикс, Инк. | Триазолил фенилбензолсульфонамиды |
| US20100234364A1 (en) * | 2006-07-14 | 2010-09-16 | Arindrajit Basak | Ccr2 inhibitors and methods of use thereof |
| CN103813793A (zh) * | 2011-07-22 | 2014-05-21 | 葛兰素史克知识产权开发有限公司 | 4-叔丁基-n-[4-氯-2-(1-氧基-吡啶-4-羰基)-苯基]-苯磺酰胺钠盐的多晶型 |
| IL316296A (en) * | 2011-07-22 | 2024-12-01 | Chemocentryx Inc | Polymorphic forms of sodium salt of 4-tert-butyl-N-[4-chloro-2-(1-oxypyridine-4-carbonyl)-phenyl]-benzenesulfonamide |
-
2012
- 2012-07-20 BR BR112014001299-7A patent/BR112014001299B1/pt active IP Right Grant
- 2012-07-20 DK DK12741219.5T patent/DK2748146T3/en active
- 2012-07-20 SI SI201230957T patent/SI2748146T1/sl unknown
- 2012-07-20 WO PCT/US2012/047559 patent/WO2013016174A1/en active Application Filing
- 2012-07-20 PL PL12741219T patent/PL2748146T3/pl unknown
- 2012-07-20 CN CN201280036358.9A patent/CN103842343B/zh active Active
- 2012-07-20 HU HUE12741219A patent/HUE032747T2/en unknown
- 2012-07-20 CA CA2841967A patent/CA2841967C/en active Active
- 2012-07-20 AU AU2012287160A patent/AU2012287160B2/en active Active
- 2012-07-20 US US13/554,169 patent/US9133124B2/en active Active
- 2012-07-20 PT PT127412195T patent/PT2748146T/pt unknown
- 2012-07-20 ES ES12741219.5T patent/ES2625286T3/es active Active
- 2012-07-20 JP JP2014522898A patent/JP6122003B2/ja active Active
- 2012-07-20 MX MX2014000660A patent/MX350269B/es active IP Right Grant
- 2012-07-20 EP EP12741219.5A patent/EP2748146B1/en active Active
- 2012-07-20 RU RU2014104993A patent/RU2607515C2/ru active
- 2012-07-20 HR HRP20170745TT patent/HRP20170745T1/hr unknown
- 2012-07-20 RS RS20170505A patent/RS56023B1/sr unknown
-
2014
- 2014-01-15 IL IL230468A patent/IL230468B/en active IP Right Grant
- 2014-01-21 ZA ZA2014/00474A patent/ZA201400474B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2012287160B2 (en) | 2017-02-02 |
| WO2013016174A1 (en) | 2013-01-31 |
| HRP20170745T1 (hr) | 2017-08-11 |
| AU2012287160A1 (en) | 2014-02-06 |
| CA2841967C (en) | 2020-06-16 |
| RU2014104993A (ru) | 2015-11-20 |
| MX350269B (es) | 2017-08-31 |
| HUE032747T2 (en) | 2017-10-30 |
| IL230468B (en) | 2018-05-31 |
| RS56023B1 (sr) | 2017-09-29 |
| MX2014000660A (es) | 2014-07-09 |
| EP2748146B1 (en) | 2017-03-08 |
| CN103842343A (zh) | 2014-06-04 |
| JP6122003B2 (ja) | 2017-04-26 |
| RU2607515C2 (ru) | 2017-01-10 |
| US20130059893A1 (en) | 2013-03-07 |
| DK2748146T3 (en) | 2017-05-22 |
| EP2748146A1 (en) | 2014-07-02 |
| BR112014001299B1 (pt) | 2022-08-16 |
| PL2748146T3 (pl) | 2017-09-29 |
| CN103842343B (zh) | 2016-08-31 |
| JP2014524931A (ja) | 2014-09-25 |
| ES2625286T3 (es) | 2017-07-19 |
| CA2841967A1 (en) | 2013-01-31 |
| IL230468A0 (en) | 2014-03-31 |
| US9133124B2 (en) | 2015-09-15 |
| ZA201400474B (en) | 2015-03-25 |
| PT2748146T (pt) | 2017-05-29 |
| BR112014001299A2 (pt) | 2017-01-10 |
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