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SI2316831T1 - 2-(morfolin-4-il)pirimidini kot inhibitorji fosfotidilinozitol (PI) 3-kinaze in njihova uporaba pri zdravljenju raka - Google Patents

2-(morfolin-4-il)pirimidini kot inhibitorji fosfotidilinozitol (PI) 3-kinaze in njihova uporaba pri zdravljenju raka

Info

Publication number
SI2316831T1
SI2316831T1 SI200332264T SI200332264T SI2316831T1 SI 2316831 T1 SI2316831 T1 SI 2316831T1 SI 200332264 T SI200332264 T SI 200332264T SI 200332264 T SI200332264 T SI 200332264T SI 2316831 T1 SI2316831 T1 SI 2316831T1
Authority
SI
Slovenia
Prior art keywords
phosphotidylinositol
pyrimidines
morpholin
cancer
treatment
Prior art date
Application number
SI200332264T
Other languages
English (en)
Slovenian (sl)
Inventor
John M. Nuss
Sabina Pecchi
Paul A. Renhowe
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Priority claimed from EP10183105A external-priority patent/EP2316831B1/en
Publication of SI2316831T1 publication Critical patent/SI2316831T1/sl

Links

SI200332264T 2002-11-21 2003-11-21 2-(morfolin-4-il)pirimidini kot inhibitorji fosfotidilinozitol (PI) 3-kinaze in njihova uporaba pri zdravljenju raka SI2316831T1 (sl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US42847302P 2002-11-21 2002-11-21
US43856803P 2003-01-07 2003-01-07
US52308103P 2003-11-19 2003-11-19
EP10183105A EP2316831B1 (en) 2002-11-21 2003-11-21 2-(morpholin-4-yl)pyrimidines as phosphotidylinositol (PI) 3-kinase inhibitors and their use in the treatment of cancer

Publications (1)

Publication Number Publication Date
SI2316831T1 true SI2316831T1 (sl) 2013-07-31

Family

ID=36077526

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200332264T SI2316831T1 (sl) 2002-11-21 2003-11-21 2-(morfolin-4-il)pirimidini kot inhibitorji fosfotidilinozitol (PI) 3-kinaze in njihova uporaba pri zdravljenju raka

Country Status (3)

Country Link
CN (1) CN1735607B (zh)
SI (1) SI2316831T1 (zh)
ZA (1) ZA200504625B (zh)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2173722B1 (en) * 2007-07-26 2012-08-29 Novartis AG Pyrimidine derivatives useful for the treatment of inflammatory or allergic conditions
KR101701109B1 (ko) * 2007-10-05 2017-02-13 베라스템, 인코포레이티드 피리미딘 치환된 퓨린 유도체
CN104245693B (zh) * 2012-12-14 2016-08-24 上海恒瑞医药有限公司 嘧啶类衍生物及其可药用盐、其制备方法及其在医药上的应用
US10173995B2 (en) * 2013-01-12 2019-01-08 Teligene Ltd. Pyridine compounds used as PI3 kinase inhibitors
CN104151256B (zh) * 2014-08-14 2016-08-24 西安交通大学 二取代苯甲酰胺类化合物及其合成方法和应用
CN105461714B (zh) * 2014-09-29 2017-11-28 山东轩竹医药科技有限公司 并环类pi3k抑制剂
CN105541792B (zh) * 2014-10-22 2018-03-13 山东轩竹医药科技有限公司 多环类pi3k抑制剂
CN109651341A (zh) * 2017-10-11 2019-04-19 上海医药工业研究院 二吗啉氰基嘧(吡)啶类衍生物及作为抗肿瘤药物应用
JP7568432B2 (ja) 2020-07-01 2024-10-16 リファインホールディングス株式会社 モルホリン誘導体およびその製造方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100355751C (zh) * 2000-03-29 2007-12-19 西克拉塞尔有限公司 2－取代的4－杂芳基－嘧啶、其组合物及其用途
JP4105949B2 (ja) * 2000-09-15 2008-06-25 バーテックス ファーマシューティカルズ インコーポレイテッド プロテインキナーゼインヒビターとして有用なピラゾール化合物

Also Published As

Publication number Publication date
CN1735607A (zh) 2006-02-15
ZA200504625B (en) 2006-09-27
CN1735607B (zh) 2010-06-09

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