SI2316831T1 - 2-(morpholin-4-yl)pyrimidines as phosphotidylinositol (PI) 3-kinase inhibitors and their use in the treatment of cancer - Google Patents
2-(morpholin-4-yl)pyrimidines as phosphotidylinositol (PI) 3-kinase inhibitors and their use in the treatment of cancerInfo
- Publication number
- SI2316831T1 SI2316831T1 SI200332264T SI200332264T SI2316831T1 SI 2316831 T1 SI2316831 T1 SI 2316831T1 SI 200332264 T SI200332264 T SI 200332264T SI 200332264 T SI200332264 T SI 200332264T SI 2316831 T1 SI2316831 T1 SI 2316831T1
- Authority
- SI
- Slovenia
- Prior art keywords
- phosphotidylinositol
- pyrimidines
- morpholin
- cancer
- treatment
- Prior art date
Links
- DUIMWXDLDBNUFD-UHFFFAOYSA-N 4-pyrimidin-2-ylmorpholine Chemical class C1COCCN1C1=NC=CC=N1 DUIMWXDLDBNUFD-UHFFFAOYSA-N 0.000 title 1
- 206010028980 Neoplasm Diseases 0.000 title 1
- 201000011510 cancer Diseases 0.000 title 1
- 229940043355 kinase inhibitor Drugs 0.000 title 1
- 239000003757 phosphotransferase inhibitor Substances 0.000 title 1
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US42847302P | 2002-11-21 | 2002-11-21 | |
| US43856803P | 2003-01-07 | 2003-01-07 | |
| US52308103P | 2003-11-19 | 2003-11-19 | |
| EP10183105A EP2316831B1 (en) | 2002-11-21 | 2003-11-21 | 2-(morpholin-4-yl)pyrimidines as phosphotidylinositol (PI) 3-kinase inhibitors and their use in the treatment of cancer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI2316831T1 true SI2316831T1 (en) | 2013-07-31 |
Family
ID=36077526
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI200332264T SI2316831T1 (en) | 2002-11-21 | 2003-11-21 | 2-(morpholin-4-yl)pyrimidines as phosphotidylinositol (PI) 3-kinase inhibitors and their use in the treatment of cancer |
Country Status (3)
| Country | Link |
|---|---|
| CN (1) | CN1735607B (en) |
| SI (1) | SI2316831T1 (en) |
| ZA (1) | ZA200504625B (en) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2173722B1 (en) * | 2007-07-26 | 2012-08-29 | Novartis AG | Pyrimidine derivatives useful for the treatment of inflammatory or allergic conditions |
| KR101701109B1 (en) * | 2007-10-05 | 2017-02-13 | 베라스템, 인코포레이티드 | Pyrimidine substituted purine derivatives |
| CN104245693B (en) * | 2012-12-14 | 2016-08-24 | 上海恒瑞医药有限公司 | Pyridine derivatives and officinal salt thereof, its preparation method and in application pharmaceutically |
| US10173995B2 (en) * | 2013-01-12 | 2019-01-08 | Teligene Ltd. | Pyridine compounds used as PI3 kinase inhibitors |
| CN104151256B (en) * | 2014-08-14 | 2016-08-24 | 西安交通大学 | Disubstituted benzenes Carbox amide and synthetic method thereof and application |
| CN105461714B (en) * | 2014-09-29 | 2017-11-28 | 山东轩竹医药科技有限公司 | And ring class PI3K inhibitor |
| CN105541792B (en) * | 2014-10-22 | 2018-03-13 | 山东轩竹医药科技有限公司 | Polycyclic class PI3K inhibitor |
| CN109651341A (en) * | 2017-10-11 | 2019-04-19 | 上海医药工业研究院 | Phonetic (pyrrole) the pyridine analog derivative of dimorpholine cyano and as anti-tumor drug application |
| JP7568432B2 (en) | 2020-07-01 | 2024-10-16 | リファインホールディングス株式会社 | Morpholine derivatives and their production method |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100355751C (en) * | 2000-03-29 | 2007-12-19 | 西克拉塞尔有限公司 | 2-substd. 4-heteroaryl-pyrimidines and their use in treatment of proliferative disorders |
| JP4105949B2 (en) * | 2000-09-15 | 2008-06-25 | バーテックス ファーマシューティカルズ インコーポレイテッド | Pyrazole compounds useful as protein kinase inhibitors |
-
2003
- 2003-11-21 SI SI200332264T patent/SI2316831T1/en unknown
- 2003-11-21 CN CN200380108239.0A patent/CN1735607B/en not_active Expired - Fee Related
-
2005
- 2005-06-06 ZA ZA200504625A patent/ZA200504625B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN1735607A (en) | 2006-02-15 |
| ZA200504625B (en) | 2006-09-27 |
| CN1735607B (en) | 2010-06-09 |
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