SI2285765T1 - Postopek priprave derivatov 1-(2-halobifenil-4-il)-ciklopropankarboksilne kisline - Google Patents

Postopek priprave derivatov 1-(2-halobifenil-4-il)-ciklopropankarboksilne kisline

Info

Publication number: SI2285765T1
Authority: SI; Slovenia
Prior art keywords: halobiphenyl; cyclopropanecarboxylic acid; preparing derivatives; preparing; derivatives
Prior art date: 2008-06-11

Application number

SI200930272T

Other languages

English (en)

Inventor

Benoit Folleas

Hubert Botte

Thomas Delacroix

Fausto Pivetti

Original Assignee

Chiesi Farma Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2008-06-11

Filing date

2009-05-08

Publication date

2012-08-31

2009-05-08 Application filed by Chiesi Farma Spa filed Critical Chiesi Farma Spa

2012-08-31 Publication of SI2285765T1 publication Critical patent/SI2285765T1/sl

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C17/00—Preparation of halogenated hydrocarbons
- C07C17/26—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton
- C07C17/263—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton by condensation reactions
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C17/00—Preparation of halogenated hydrocarbons
- C07C17/093—Preparation of halogenated hydrocarbons by replacement by halogens
- C07C17/10—Preparation of halogenated hydrocarbons by replacement by halogens of hydrogen atoms
- C07C17/14—Preparation of halogenated hydrocarbons by replacement by halogens of hydrogen atoms in the side-chain of aromatic compounds
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C253/00—Preparation of carboxylic acid nitriles
- C07C253/14—Preparation of carboxylic acid nitriles by reaction of cyanides with halogen-containing compounds with replacement of halogen atoms by cyano groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C253/00—Preparation of carboxylic acid nitriles
- C07C253/30—Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/09—Preparation of carboxylic acids or their salts, halides or anhydrides from carboxylic acid esters or lactones
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Toxicology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Oil, Petroleum & Natural Gas (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Psychiatry (AREA)
Hospice & Palliative Care (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

SI200930272T 2008-06-11 2009-05-08 Postopek priprave derivatov 1-(2-halobifenil-4-il)-ciklopropankarboksilne kisline SI2285765T1 (sl)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
EP08158022A EP2133322A1 (en)	2008-06-11	2008-06-11	Process of preparing derivatives of 1-(2-halobiphenyl-4-yl)-cyclopropanecarboxylic acid
PCT/EP2009/003288 WO2009149797A1 (en)	2008-06-11	2009-05-08	Process of preparing derivatives of 1-(2-halobiphenyl-4-yl)-cyclopropanecarboxylic acid
EP09761360A EP2285765B1 (en)	2008-06-11	2009-05-08	Process of preparing derivatives of 1-(2-halobiphenyl-4-yl)-cyclopropanecarboxylic acid

Publications (1)

Publication Number	Publication Date
SI2285765T1 true SI2285765T1 (sl)	2012-08-31

Family

ID=40120119

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SI200930272T SI2285765T1 (sl)	2008-06-11	2009-05-08	Postopek priprave derivatov 1-(2-halobifenil-4-il)-ciklopropankarboksilne kisline

Country Status (28)

Country	Link
US (1)	US8076505B2 (sl)
EP (2)	EP2133322A1 (sl)
JP (1)	JP5642067B2 (sl)
KR (1)	KR101257217B1 (sl)
CN (1)	CN102046576B (sl)
AT (1)	ATE552230T1 (sl)
AU (1)	AU2009256959B2 (sl)
BR (1)	BRPI0909560A2 (sl)
CA (1)	CA2723878C (sl)
CO (1)	CO6331461A2 (sl)
DK (1)	DK2285765T3 (sl)
ES (1)	ES2384368T3 (sl)
GE (1)	GEP20135800B (sl)
HK (1)	HK1152292A1 (sl)
HR (1)	HRP20120517T1 (sl)
IL (1)	IL209209A (sl)
MA (1)	MA32297B1 (sl)
ME (1)	ME01160B (sl)
MX (1)	MX2010012285A (sl)
MY (1)	MY150280A (sl)
NZ (1)	NZ589087A (sl)
PL (1)	PL2285765T3 (sl)
PT (1)	PT2285765E (sl)
RU (1)	RU2502721C2 (sl)
SI (1)	SI2285765T1 (sl)
UA (1)	UA101835C2 (sl)
WO (1)	WO2009149797A1 (sl)
ZA (1)	ZA201007977B (sl)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
KR101152448B1 (ko) *	2003-02-21	2012-07-02	키에시 파르마슈티시 엣스. 피. 에이.	신경 퇴행성 질환의 치료를 위한 1-페닐알캔카복실산 추출물의 제조방법
BR112012002500A2 (pt) *	2009-08-04	2018-03-13	Chiesi Farm Spa	Processo para o preparo de derivados de ácido 1- (2-halobifenil-4-yl) - ciclopropanocarboxílico
WO2011120778A1 (en) *	2010-04-01	2011-10-06	Chiesi Farmaceutici S.P.A.	Novel polymorphs and salts
CN102844290B (zh)	2010-04-21	2015-06-17	奇斯药制品公司	用于治疗转甲状腺素蛋白淀粉样变性的1-(2-氟联苯-4-基)-烷基羧酸衍生物
CN102905701A (zh)	2010-06-04	2013-01-30	奇斯药制品公司	用于治疗朊病毒病的1-(2-氟联苯-4-基)-环丙烷羧酸衍生物
US9592210B2 (en)	2011-12-22	2017-03-14	Chiesi Farmaceutici S.P.A.	1-phenylalkanecarboxylic acid derivatives for the treatment of cognitive impairment
BR112014023670A8 (pt)	2012-04-04	2017-07-25	Chiesi Farm Spa	Composto, composição farmacêutica e suo de um composto
WO2014206898A1 (en)	2013-06-24	2014-12-31	Chiesi Farmaceutici S.P.A.	Improved process for the preparation of derivatives of 1-(2-fluoro[1,1'-biphenyl]-4-yl)-cyclopropanecarboxylic acid
EP2818460A1 (en)	2013-06-24	2014-12-31	ZaCh System S.p.A.	Cyclopropanation of substituted phenylacetonitriles or phenyl acetates
US20150335596A1 (en)	2014-05-26	2015-11-26	Chiesi Farmaceutici S.P.A.	1-(2-fluorobiphenyl-4-yl)-cyclopropanecarboxylic acid derivatives for the treatment of down's syndrome
CN107698462A (zh) *	2017-10-10	2018-02-16	重庆科脉生物化工有限公司	一种1‑氨基‑1‑环丙腈盐酸盐的制备方法
KR20240054333A (ko)	2021-08-31	2024-04-25	세레스파이어 인코포레이티드	공결정

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP4507294B2 (ja) *	1999-05-27	2010-07-21	チッソ株式会社	ビアリール誘導体の製造方法
JP4502293B2 (ja) *	1999-06-04	2010-07-14	長瀬産業株式会社	軸不斉を有する光学活性な４級アンモニウム塩、その製法およびα−アミノ酸誘導体の不斉合成への応用
JP2004091342A (ja) *	2002-08-29	2004-03-25	Matsushita Electric Ind Co Ltd	芳香族メチリデン化合物、それを製造するための化合物、それらの製造方法、及び芳香族メチリデン化合物を用いた有機電界発光素子
ITMI20030311A1 (it) *	2003-02-21	2004-08-22	Chiesi Farma Spa	Acidi 2-fenil-2-dialchil-acetici per il trattamento della malattia di alzheimer.
KR101152448B1 (ko) *	2003-02-21	2012-07-02	키에시 파르마슈티시 엣스. 피. 에이.	신경 퇴행성 질환의 치료를 위한 1-페닐알캔카복실산 추출물의 제조방법
EP1650183A1 (en) *	2004-10-21	2006-04-26	Cellzome Ag	(Benzyloxy-biphenyl) acetic acids and derivatives thereof and their use in therapy
US7524870B2 (en) *	2004-12-03	2009-04-28	Hoffmann-La Roche Inc.	Biaryloxymethylarenecarboxylic acids as glycogen synthase activators
JP2008546651A (ja) *	2005-06-14	2008-12-25	メルクフロストカナダリミテツド	モノアミンオキシダーゼａ及びｂの可逆的阻害剤
JP5272345B2 (ja) *	2006-08-28	2013-08-28	東ソー株式会社	ヘテロアセン誘導体、テトラハロターフェニル誘導体及びそれらの製造方法
BR112012002500A2 (pt) *	2009-08-04	2018-03-13	Chiesi Farm Spa	Processo para o preparo de derivados de ácido 1- (2-halobifenil-4-yl) - ciclopropanocarboxílico

2008
- 2008-06-11 EP EP08158022A patent/EP2133322A1/en not_active Withdrawn
2009
- 2009-05-08 CA CA2723878A patent/CA2723878C/en active Active
- 2009-05-08 EP EP09761360A patent/EP2285765B1/en active Active
- 2009-05-08 BR BRPI0909560A patent/BRPI0909560A2/pt not_active IP Right Cessation
- 2009-05-08 MY MYPI2010005220A patent/MY150280A/en unknown
- 2009-05-08 ES ES09761360T patent/ES2384368T3/es active Active
- 2009-05-08 NZ NZ589087A patent/NZ589087A/en not_active IP Right Cessation
- 2009-05-08 PT PT09761360T patent/PT2285765E/pt unknown
- 2009-05-08 GE GEAP200911997A patent/GEP20135800B/en unknown
- 2009-05-08 AU AU2009256959A patent/AU2009256959B2/en not_active Ceased
- 2009-05-08 PL PL09761360T patent/PL2285765T3/pl unknown
- 2009-05-08 RU RU2010146299/04A patent/RU2502721C2/ru not_active IP Right Cessation
- 2009-05-08 SI SI200930272T patent/SI2285765T1/sl unknown
- 2009-05-08 WO PCT/EP2009/003288 patent/WO2009149797A1/en active Application Filing
- 2009-05-08 MX MX2010012285A patent/MX2010012285A/es active IP Right Grant
- 2009-05-08 DK DK09761360.8T patent/DK2285765T3/da active
- 2009-05-08 UA UAA201013287A patent/UA101835C2/uk unknown
- 2009-05-08 CN CN2009801196647A patent/CN102046576B/zh not_active Expired - Fee Related
- 2009-05-08 KR KR1020107027903A patent/KR101257217B1/ko not_active IP Right Cessation
- 2009-05-08 ME MEP-2010-200A patent/ME01160B/me unknown
- 2009-05-08 JP JP2011512846A patent/JP5642067B2/ja not_active Expired - Fee Related
- 2009-05-08 AT AT09761360T patent/ATE552230T1/de active
- 2009-05-15 US US12/466,660 patent/US8076505B2/en active Active
2010
- 2010-11-08 ZA ZA2010/07977A patent/ZA201007977B/en unknown
- 2010-11-09 IL IL209209A patent/IL209209A/en not_active IP Right Cessation
- 2010-11-11 MA MA33338A patent/MA32297B1/fr unknown
- 2010-11-16 CO CO10143043A patent/CO6331461A2/es active IP Right Grant
2011
- 2011-06-21 HK HK11106325.0A patent/HK1152292A1/xx not_active IP Right Cessation
2012
- 2012-06-20 HR HRP20120517AT patent/HRP20120517T1/hr unknown

Also Published As

Publication number	Publication date
PT2285765E (pt)	2012-06-21
MX2010012285A (es)	2010-12-01
UA101835C2 (uk)	2013-05-13
CO6331461A2 (es)	2011-10-20
AU2009256959A1 (en)	2009-12-17
RU2502721C2 (ru)	2013-12-27
KR20110010633A (ko)	2011-02-01
CN102046576B (zh)	2013-08-21
JP2011523953A (ja)	2011-08-25
EP2133322A1 (en)	2009-12-16
BRPI0909560A2 (pt)	2015-09-22
CA2723878C (en)	2016-06-28
GEP20135800B (en)	2013-04-10
JP5642067B2 (ja)	2014-12-17
IL209209A (en)	2014-05-28
US20090312426A1 (en)	2009-12-17
ATE552230T1 (de)	2012-04-15
AU2009256959B2 (en)	2014-03-27
IL209209A0 (en)	2011-01-31
ME01160B (me)	2013-03-20
HK1152292A1 (en)	2012-02-24
WO2009149797A1 (en)	2009-12-17
PL2285765T3 (pl)	2012-08-31
EP2285765B1 (en)	2012-04-04
DK2285765T3 (da)	2012-06-04
CN102046576A (zh)	2011-05-04
US8076505B2 (en)	2011-12-13
MA32297B1 (fr)	2011-05-02
ZA201007977B (en)	2012-02-29
EP2285765A1 (en)	2011-02-23
KR101257217B1 (ko)	2013-04-22
MY150280A (en)	2013-12-31
HRP20120517T1 (hr)	2012-07-31
ES2384368T3 (es)	2012-07-04
RU2010146299A (ru)	2012-07-20
NZ589087A (en)	2012-03-30
CA2723878A1 (en)	2009-12-17

Publication	Publication Date	Title
HK1152292A1 (en)	2012-02-24	Process of preparing derivatives of 1-(2-halobiphenyl-4-yl)- cyclopropanecarboxylic acid
TW200801027A (en)	2008-01-01	Processes for production of 4-(biphenylyl)azetidin-2-one phosphonic acids
IN2012DN02751A (sl)	2015-09-18
HK1166074A1 (en)	2012-10-19	Furopyrimidinedione derivatives as trpa1 modulators
NZ592497A (en)	2013-02-22	Derivatives of 1-amino-2-cyclobutylethylboronic acid
NZ600119A (en)	2013-07-26	Process and intermediates for the preparation of 5-biphenyl-4-yl-2-methylpentanoic acid derivatives
MX2010008899A (es)	2010-10-25	Procedimiento para la sintesis regioselectiva de derivados de acido 1-alquil-3-haloalquil-pirazol-4-carboxilico.
UA102817C2 (ru)	2013-08-27	Способ синтеза агомелатина
GEP20125512B (en)	2012-05-10	Process for synthesis of agomelatin
MX2012001411A (es)	2012-03-29	Proceso para la preparacion de derivados de acido 1-(2-halobifenil-4-il)-ciclopropanocarboxilico.
MX2011009898A (es)	2011-09-30	Proceso para la obtencion de derivados de acido propionico.
HK1168102A1 (en)	2012-12-21	Process for the preparation of a compound useful as an inhibitor of tafia
WO2010004578A3 (en)	2010-06-24	Novel and improved processes for the preparation of paliperidone
UA106988C2 (uk)	2014-11-10	Спосіб одержання 1-бензил-3-гідроксиметил-1h-індазолу і його похідних та необхідні проміжні сполуки магнію
MX2010009926A (es)	2010-09-28	Nuevo proceso para la preparacion de derivados de acido ciclohexancarboxilico.
MX2010009876A (es)	2010-09-28	Nuevo proceso para la preparacion de derivados de acido ciclohexanocarboxilico por medio del derivado de ciclohexanocarboxamida correspondiente.
UA106195C2 (ru)	2014-08-11	Способ синтеза агомелатина
UA102816C2 (ru)	2013-08-27	Способ синтеза кристаллической формы v агомелатина
WO2010113182A8 (en)	2010-11-25	Intermediates in the preparation of 1,4-diphenyl azetidinone
MX2013004193A (es)	2013-06-05	Procedimiento para la preparacion de derivados de acido 3-(6-amino-piridin-3-il)-2-acrilico.
MX2011009734A (es)	2011-09-29	Nuevo procedimiento de preparacion de compuestos de enaminocarbonilio.
MY181791A (en)	2021-01-07	Process for the preparation of propionic acid derivatives
TN2010000531A1 (en)	2012-05-24	Process of preparing derivatives of 1-(2-halobiphenyl-4-yl)-cyclopropanecarboxylic acid
GB0612027D0 (en)	2006-07-26	Novel process
MX2011009731A (es)	2011-09-29	Nuevo procedimiento de preparacion de compuestos de enaminocarbonilo.