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SI2030981T1 - Spojine za inhibiranje proteasomskega encima - Google Patents

Spojine za inhibiranje proteasomskega encima

Info

Publication number
SI2030981T1
SI2030981T1 SI200531893T SI200531893T SI2030981T1 SI 2030981 T1 SI2030981 T1 SI 2030981T1 SI 200531893 T SI200531893 T SI 200531893T SI 200531893 T SI200531893 T SI 200531893T SI 2030981 T1 SI2030981 T1 SI 2030981T1
Authority
SI
Slovenia
Prior art keywords
compounds
enzyme inhibition
proteasome enzyme
proteasome
inhibition
Prior art date
Application number
SI200531893T
Other languages
English (en)
Inventor
Mark S. Smyth
Guy J. Laidig
Ronald T. Borchardt
Barry A. Bunin
Craig M. Crews
John H. Musser
Kevin D. Shenk
Peggy A. Radel
Original Assignee
Onyx Therapeutics, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Onyx Therapeutics, Inc. filed Critical Onyx Therapeutics, Inc.
Publication of SI2030981T1 publication Critical patent/SI2030981T1/sl

Links

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    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0812—Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic
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    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
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    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0827—Tripeptides containing heteroatoms different from O, S, or N
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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  • Proteomics, Peptides & Aminoacids (AREA)
  • Pulmonology (AREA)
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  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
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  • Physical Education & Sports Medicine (AREA)
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  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Rheumatology (AREA)
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SI200531893T 2004-05-10 2005-05-09 Spojine za inhibiranje proteasomskega encima SI2030981T1 (sl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US56988504P 2004-05-10 2004-05-10
US61004004P 2004-09-14 2004-09-14
US63436604P 2004-12-07 2004-12-07
EP08164241.5A EP2030981B1 (en) 2004-05-10 2005-05-09 Compounds for proteasome enzyme inhibition

Publications (1)

Publication Number Publication Date
SI2030981T1 true SI2030981T1 (sl) 2014-11-28

Family

ID=34967797

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200531893T SI2030981T1 (sl) 2004-05-10 2005-05-09 Spojine za inhibiranje proteasomskega encima

Country Status (18)

Country Link
US (3) US8088741B2 (sl)
EP (3) EP2564834A3 (sl)
JP (3) JP5108509B2 (sl)
CN (2) CN102875642A (sl)
AU (1) AU2005243168B2 (sl)
BR (1) BRPI0510802A (sl)
CA (1) CA2565407A1 (sl)
CY (1) CY1115605T1 (sl)
DK (1) DK2030981T3 (sl)
ES (1) ES2510840T3 (sl)
HK (1) HK1127618A1 (sl)
IL (4) IL179020A (sl)
PL (1) PL2030981T3 (sl)
PT (1) PT2030981E (sl)
RU (1) RU2384585C2 (sl)
SG (1) SG185963A1 (sl)
SI (1) SI2030981T1 (sl)
WO (1) WO2005111008A2 (sl)

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PT2623113T (pt) 2005-11-09 2017-07-14 Onyx Therapeutics Inc Compostos para inibição de enzimas
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TWI504598B (zh) 2009-03-20 2015-10-21 Onyx Therapeutics Inc 結晶性三肽環氧酮蛋白酶抑制劑
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MA34133B1 (fr) 2010-03-01 2013-04-03 Onyx Therapeutics Inc Composes pour inhibiteurs de l'immunoproteasome
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JP6238900B2 (ja) 2011-10-28 2017-11-29 ミレニアム ファーマシューティカルズ， インコーポレイテッドＭｉｌｌｅｎｎｉｕｍ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ． Ｎａｅ阻害物質に対する応答のバイオマーカー
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CN104204797B (zh) 2012-01-24 2017-05-31 米伦纽姆医药公司 治疗癌症的方法
GB2523211B (en) 2012-01-27 2020-03-18 Univ Jefferson MCT protein inhibitor-related prognostic and therapeutic methods
JP6508944B2 (ja) 2012-02-15 2019-05-08 サイデックス・ファーマシューティカルズ・インコーポレイテッド シクロデキストリン誘導体のための製造方法
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