SI1941026T1 - Postopki za proizvodnjo beljakovin z uporabo protisenescenčnih spojin - Google Patents
Postopki za proizvodnjo beljakovin z uporabo protisenescenčnih spojinInfo
- Publication number
- SI1941026T1 SI1941026T1 SI200631796T SI200631796T SI1941026T1 SI 1941026 T1 SI1941026 T1 SI 1941026T1 SI 200631796 T SI200631796 T SI 200631796T SI 200631796 T SI200631796 T SI 200631796T SI 1941026 T1 SI1941026 T1 SI 1941026T1
- Authority
- SI
- Slovenia
- Prior art keywords
- methods
- protein production
- senescence compounds
- senescence
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0018—Culture media for cell or tissue culture
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/32—Amino acids
- C12N2500/33—Amino acids other than alpha-amino carboxylic acids, e.g. beta-amino acids, taurine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/998—Proteins not provided for elsewhere
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
- C12N2510/02—Cells for production
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Cell Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US72957305P | 2005-10-24 | 2005-10-24 | |
PCT/US2006/041256 WO2007050498A2 (en) | 2005-10-24 | 2006-10-24 | Methods of protein production using anti-senescence compounds |
EP06844211.0A EP1941026B1 (en) | 2005-10-24 | 2006-10-24 | Methods of protein production using anti-senescence compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
SI1941026T1 true SI1941026T1 (sl) | 2014-07-31 |
Family
ID=37873105
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SI200631796T SI1941026T1 (sl) | 2005-10-24 | 2006-10-24 | Postopki za proizvodnjo beljakovin z uporabo protisenescenčnih spojin |
Country Status (24)
Country | Link |
---|---|
US (1) | US20070110743A1 (sl) |
EP (1) | EP1941026B1 (sl) |
JP (2) | JP2009512459A (sl) |
KR (1) | KR101402634B1 (sl) |
CN (1) | CN101297027B (sl) |
AR (1) | AR058140A1 (sl) |
AU (1) | AU2006306433B2 (sl) |
BR (1) | BRPI0617744A2 (sl) |
CA (1) | CA2627003C (sl) |
CR (1) | CR9897A (sl) |
DK (1) | DK1941026T3 (sl) |
EC (1) | ECSP088395A (sl) |
ES (1) | ES2485374T3 (sl) |
HK (1) | HK1120552A1 (sl) |
IL (1) | IL190550A (sl) |
NI (1) | NI200800111A (sl) |
NO (1) | NO20081622L (sl) |
PE (1) | PE20070796A1 (sl) |
PL (1) | PL1941026T3 (sl) |
PT (1) | PT1941026E (sl) |
RU (1) | RU2491347C2 (sl) |
SI (1) | SI1941026T1 (sl) |
TW (1) | TW200736397A (sl) |
WO (1) | WO2007050498A2 (sl) |
Families Citing this family (38)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2440487T3 (es) | 2006-07-13 | 2014-01-29 | Wyeth Llc | Producción de glucoproteínas |
AU2007294731B2 (en) | 2006-09-13 | 2014-04-17 | Abbvie Inc. | Cell culture improvements |
US8911964B2 (en) | 2006-09-13 | 2014-12-16 | Abbvie Inc. | Fed-batch method of making human anti-TNF-alpha antibody |
TW200902708A (en) * | 2007-04-23 | 2009-01-16 | Wyeth Corp | Methods of protein production using anti-senescence compounds |
TW201024318A (en) | 2008-10-20 | 2010-07-01 | Abbott Lab | Isolation and purification of antibodies using protein A affinity chromatography |
SG195577A1 (en) | 2008-10-20 | 2013-12-30 | Abbott Lab | Viral inactivation during purification of antibodies |
WO2011018472A2 (en) | 2009-08-14 | 2011-02-17 | Basf Se | Methods in cell cultures, and related inventions, employing certain additives |
SG187198A1 (en) | 2010-08-05 | 2013-03-28 | Amgen Inc | Dipeptides to enhance yield and viability from cell cultures |
US20130224855A1 (en) * | 2010-08-31 | 2013-08-29 | Abhishek Gupta | Culture medium for eukaryotic cells |
EP2702077A2 (en) | 2011-04-27 | 2014-03-05 | AbbVie Inc. | Methods for controlling the galactosylation profile of recombinantly-expressed proteins |
TW201247874A (en) * | 2011-05-25 | 2012-12-01 | United Biomedical Inc | Method for producing the activity of bone activating protein |
US9067990B2 (en) | 2013-03-14 | 2015-06-30 | Abbvie, Inc. | Protein purification using displacement chromatography |
WO2013158273A1 (en) | 2012-04-20 | 2013-10-24 | Abbvie Inc. | Methods to modulate c-terminal lysine variant distribution |
US9505833B2 (en) | 2012-04-20 | 2016-11-29 | Abbvie Inc. | Human antibodies that bind human TNF-alpha and methods of preparing the same |
US9334319B2 (en) | 2012-04-20 | 2016-05-10 | Abbvie Inc. | Low acidic species compositions |
US9249182B2 (en) | 2012-05-24 | 2016-02-02 | Abbvie, Inc. | Purification of antibodies using hydrophobic interaction chromatography |
US9512214B2 (en) | 2012-09-02 | 2016-12-06 | Abbvie, Inc. | Methods to control protein heterogeneity |
WO2014035475A1 (en) | 2012-09-02 | 2014-03-06 | Abbvie Inc. | Methods to control protein heterogeneity |
AU2014229557B2 (en) * | 2013-03-13 | 2017-12-07 | Anteis Sa | Peptides for skin rejuvenation and methods of using the same |
US8921526B2 (en) | 2013-03-14 | 2014-12-30 | Abbvie, Inc. | Mutated anti-TNFα antibodies and methods of their use |
US9499614B2 (en) | 2013-03-14 | 2016-11-22 | Abbvie Inc. | Methods for modulating protein glycosylation profiles of recombinant protein therapeutics using monosaccharides and oligosaccharides |
US9017687B1 (en) | 2013-10-18 | 2015-04-28 | Abbvie, Inc. | Low acidic species compositions and methods for producing and using the same using displacement chromatography |
EP2970875B1 (en) * | 2013-03-15 | 2020-04-15 | F.Hoffmann-La Roche Ag | Cell culture compositions with antioxidants and methods for polypeptide production |
US9598667B2 (en) | 2013-10-04 | 2017-03-21 | Abbvie Inc. | Use of metal ions for modulation of protein glycosylation profiles of recombinant proteins |
CA2926588C (en) | 2013-10-16 | 2020-07-21 | Oncobiologics, Inc. | Buffer formulations for enhanced antibody stability |
US8946395B1 (en) | 2013-10-18 | 2015-02-03 | Abbvie Inc. | Purification of proteins using hydrophobic interaction chromatography |
US9181337B2 (en) | 2013-10-18 | 2015-11-10 | Abbvie, Inc. | Modulated lysine variant species compositions and methods for producing and using the same |
US9085618B2 (en) | 2013-10-18 | 2015-07-21 | Abbvie, Inc. | Low acidic species compositions and methods for producing and using the same |
US20150139988A1 (en) | 2013-11-15 | 2015-05-21 | Abbvie, Inc. | Glycoengineered binding protein compositions |
CN104398398A (zh) * | 2014-10-27 | 2015-03-11 | 陈少威 | 一种细胞量子动力素(平衡剂)及其使用方法 |
MA40864A (fr) * | 2014-10-31 | 2017-09-05 | Biogen Ma Inc | Hypotaurine, gaba, bêta-alanine et choline pour la régulation de l'accumulation de sous-produits résiduaires dans des procédés de culture de cellules mammifères |
EP3247718B1 (en) | 2015-01-21 | 2021-09-01 | Outlook Therapeutics, Inc. | Modulation of charge variants in a monoclonal antibody composition |
TW202440904A (zh) | 2015-08-04 | 2024-10-16 | 美商再生元醫藥公司 | 補充牛磺酸之細胞培養基及用法(二) |
CN108350416A (zh) | 2015-11-09 | 2018-07-31 | 百时美施贵宝公司 | 操纵在cho细胞中产生的多肽的品质属性的方法 |
CN109153717A (zh) * | 2016-01-06 | 2019-01-04 | 安口生物公司 | 减少单克隆抗体组合物中的高分子量物类、酸性电荷物类和片段 |
JP7084308B2 (ja) | 2016-02-03 | 2022-06-14 | アウトルック セラピューティクス,インコーポレイティド | 抗体安定性を増大させるための緩衝液製剤 |
MX2020003555A (es) * | 2017-10-16 | 2020-08-03 | Regeneron Pharma | Sistemas de espectroscopia raman in situ y metodos para controlar variables de proceso en cultivos celulares. |
WO2025053166A1 (ja) * | 2023-09-05 | 2025-03-13 | 味の素株式会社 | 培地組成物 |
Family Cites Families (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8308235D0 (en) * | 1983-03-25 | 1983-05-05 | Celltech Ltd | Polypeptides |
US4816567A (en) * | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
US5225539A (en) * | 1986-03-27 | 1993-07-06 | Medical Research Council | Recombinant altered antibodies and methods of making altered antibodies |
US5223409A (en) * | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
US5530101A (en) * | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
EP0417563B1 (de) * | 1989-09-12 | 2000-07-05 | F. Hoffmann-La Roche Ag | TNF-bindende Proteine |
US5859205A (en) * | 1989-12-21 | 1999-01-12 | Celltech Limited | Humanised antibodies |
WO1992009298A1 (en) | 1990-11-23 | 1992-06-11 | Peptide Technology Ltd. | The delay, prevention and/or reversal of cell senescence |
DE122004000008I1 (de) * | 1991-06-14 | 2005-06-09 | Genentech Inc | Humanisierter Heregulin Antikörper. |
RU2245365C2 (ru) * | 1994-01-03 | 2005-01-27 | Генентек Инк. | Тромбопоэтин |
US5830761A (en) * | 1995-06-07 | 1998-11-03 | Genetics Institute, Inc. | Medium and methods for culturing mammalian cho cells |
RU2134120C1 (ru) * | 1995-06-26 | 1999-08-10 | Безруков Михаил Васильевич | Средство для стабилизации пептидной связи в белковом препарате |
PT859841E (pt) * | 1995-08-18 | 2002-11-29 | Morphosys Ag | Bibliotecas de proteinas/ (poli) peptidos |
JP4306813B2 (ja) * | 1995-09-19 | 2009-08-05 | アスビオファーマ株式会社 | 動物細胞の新規培養方法 |
US6146847A (en) * | 1996-11-01 | 2000-11-14 | Genespan Corporation | Stabilized transient gene expression |
JP4215172B2 (ja) * | 1996-12-03 | 2009-01-28 | アムジェン フレモント インク. | 複数のV▲下H▼およびV▲下κ▼領域を含むヒトIg遺伝子座を有するトランスジェニック哺乳動物、ならびにそれから産生される抗体 |
US20030040095A1 (en) * | 2001-03-16 | 2003-02-27 | Achille Arini | Method for the production of pharmaceutically active recombinant proteins |
WO2002086101A2 (en) * | 2001-04-24 | 2002-10-31 | Innogenetics N.V. | Core-glycosylated hcv envelope proteins |
EP1575998A4 (en) * | 2002-12-23 | 2007-07-25 | Bristol Myers Squibb Co | PROCESS FOR CULTIVATING MAMMALIAN CELLS FOR PROTEIN PRODUCTION |
BRPI0415887B1 (pt) * | 2003-10-27 | 2021-01-26 | Wyeth | métodos para a remoção de agregados de elevado peso molecular utilizando cromatografia de hidroxiapatita |
WO2005064013A1 (en) | 2003-12-23 | 2005-07-14 | Bart Janssen | The use of carnosine metabolism-associated genes to determine genetic predisposition/susceptibility to diabetic nephropathy |
US7335491B2 (en) * | 2004-08-27 | 2008-02-26 | Wyeth Research Ireland Limited | Production of anti-abeta |
TWI364458B (en) * | 2004-08-27 | 2012-05-21 | Wyeth Res Ireland Ltd | Production of tnfr-lg |
US7294484B2 (en) * | 2004-08-27 | 2007-11-13 | Wyeth Research Ireland Limited | Production of polypeptides |
US7426440B2 (en) * | 2004-09-24 | 2008-09-16 | Nutritional Bioscience Ltd. | Repair and protection factor scoring method for bioactive agents |
-
2006
- 2006-10-23 AR ARP060104624A patent/AR058140A1/es unknown
- 2006-10-23 PE PE2006001284A patent/PE20070796A1/es not_active Application Discontinuation
- 2006-10-24 PL PL06844211T patent/PL1941026T3/pl unknown
- 2006-10-24 TW TW095139179A patent/TW200736397A/zh unknown
- 2006-10-24 US US11/585,607 patent/US20070110743A1/en not_active Abandoned
- 2006-10-24 AU AU2006306433A patent/AU2006306433B2/en active Active
- 2006-10-24 WO PCT/US2006/041256 patent/WO2007050498A2/en active Application Filing
- 2006-10-24 SI SI200631796T patent/SI1941026T1/sl unknown
- 2006-10-24 CN CN2006800396267A patent/CN101297027B/zh active Active
- 2006-10-24 RU RU2008113220/10A patent/RU2491347C2/ru active
- 2006-10-24 PT PT68442110T patent/PT1941026E/pt unknown
- 2006-10-24 BR BRPI0617744-1A patent/BRPI0617744A2/pt not_active Application Discontinuation
- 2006-10-24 JP JP2008537834A patent/JP2009512459A/ja not_active Withdrawn
- 2006-10-24 DK DK06844211.0T patent/DK1941026T3/da active
- 2006-10-24 KR KR1020087009856A patent/KR101402634B1/ko not_active Expired - Fee Related
- 2006-10-24 CA CA2627003A patent/CA2627003C/en active Active
- 2006-10-24 ES ES06844211.0T patent/ES2485374T3/es active Active
- 2006-10-24 EP EP06844211.0A patent/EP1941026B1/en active Active
-
2008
- 2008-04-01 IL IL190550A patent/IL190550A/en active IP Right Grant
- 2008-04-02 NO NO20081622A patent/NO20081622L/no not_active Application Discontinuation
- 2008-04-09 NI NI200800111A patent/NI200800111A/es unknown
- 2008-04-18 CR CR9897A patent/CR9897A/es not_active Application Discontinuation
- 2008-04-23 EC EC2008008395A patent/ECSP088395A/es unknown
- 2008-12-03 HK HK08113179.8A patent/HK1120552A1/xx unknown
-
2013
- 2013-04-26 JP JP2013094315A patent/JP5907928B2/ja not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
ES2485374T3 (es) | 2014-08-13 |
CR9897A (es) | 2008-07-29 |
CN101297027B (zh) | 2013-04-03 |
AU2006306433A1 (en) | 2007-05-03 |
BRPI0617744A2 (pt) | 2011-08-02 |
JP2013165728A (ja) | 2013-08-29 |
US20070110743A1 (en) | 2007-05-17 |
KR20080063365A (ko) | 2008-07-03 |
AU2006306433B2 (en) | 2013-04-18 |
TW200736397A (en) | 2007-10-01 |
RU2008113220A (ru) | 2009-12-10 |
WO2007050498A3 (en) | 2007-07-12 |
RU2491347C2 (ru) | 2013-08-27 |
NO20081622L (no) | 2008-06-18 |
CN101297027A (zh) | 2008-10-29 |
IL190550A0 (en) | 2008-11-03 |
PE20070796A1 (es) | 2007-08-15 |
EP1941026A2 (en) | 2008-07-09 |
ECSP088395A (es) | 2008-05-30 |
DK1941026T3 (da) | 2014-07-21 |
WO2007050498A2 (en) | 2007-05-03 |
NI200800111A (es) | 2009-03-03 |
HK1120552A1 (en) | 2009-04-03 |
KR101402634B1 (ko) | 2014-06-03 |
CA2627003C (en) | 2018-08-28 |
PT1941026E (pt) | 2014-07-31 |
JP5907928B2 (ja) | 2016-04-26 |
PL1941026T3 (pl) | 2014-12-31 |
EP1941026B1 (en) | 2014-06-04 |
CA2627003A1 (en) | 2007-05-03 |
JP2009512459A (ja) | 2009-03-26 |
AR058140A1 (es) | 2008-01-23 |
IL190550A (en) | 2017-01-31 |
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