SI1896006T1 - Postopek za izdelavo granul, ki vsebujejo entakapon, za oralne odmerne oblike - Google Patents

Postopek za izdelavo granul, ki vsebujejo entakapon, za oralne odmerne oblike

Info

Publication number: SI1896006T1
Authority: SI; Slovenia
Prior art keywords: entacapone; oral dosage; manufacturing; dosage forms; containing granules
Prior art date: 2005-06-08

Application number

SI200630519T

Other languages

English (en)

Inventor

Kari Vahervuo

Original Assignee

Orion Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2005-06-08

Filing date

2006-06-07

Publication date

2010-02-26

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37400847&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SI1896006(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2006-06-07 Application filed by Orion Corp filed Critical Orion Corp

2010-02-26 Publication of SI1896006T1 publication Critical patent/SI1896006T1/sl

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/275—Nitriles; Isonitriles
- A61K31/277—Nitriles; Isonitriles having a ring, e.g. verapamil
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/275—Nitriles; Isonitriles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/2853—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers, poly(lactide-co-glycolide)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Epidemiology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Psychology (AREA)
Medicinal Preparation (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

SI200630519T 2005-06-08 2006-06-07 Postopek za izdelavo granul, ki vsebujejo entakapon, za oralne odmerne oblike SI1896006T1 (sl)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US68833405P	2005-06-08	2005-06-08
EP06755404A EP1896006B1 (en)	2005-06-08	2006-06-07	A manufacturing method for entacapone-containing granules for oral dosage forms

Publications (1)

Publication Number	Publication Date
SI1896006T1 true SI1896006T1 (sl)	2010-02-26

Family

ID=37400847

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SI200630519T SI1896006T1 (sl)	2005-06-08	2006-06-07	Postopek za izdelavo granul, ki vsebujejo entakapon, za oralne odmerne oblike

Country Status (19)

Country	Link
US (3)	US20080187590A1 (sl)
EP (5)	EP1896006B1 (sl)
JP (2)	JP5336181B2 (sl)
KR (2)	KR101617990B1 (sl)
CN (1)	CN101184483B (sl)
AT (1)	ATE444746T1 (sl)
AU (1)	AU2006256724B2 (sl)
CA (1)	CA2611114C (sl)
CY (1)	CY1109587T1 (sl)
DE (1)	DE602006009652D1 (sl)
DK (1)	DK1896006T3 (sl)
EA (1)	EA013161B1 (sl)
ES (1)	ES2311442T3 (sl)
MX (1)	MX2007015377A (sl)
NO (1)	NO345046B1 (sl)
PL (1)	PL1896006T3 (sl)
PT (2)	PT1896006E (sl)
SI (1)	SI1896006T1 (sl)
WO (1)	WO2006131591A2 (sl)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
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GB2429645A (en) *	2006-03-10	2007-03-07	Sekhsaria Chemicals Ltd	Solid pharmaceutical composition comprising a COMT inhibitor, a starch and a wetting agent
EP2114374A4 (en) *	2006-12-27	2011-03-23	Wockhardt Research Center	PHARMACEUTICAL COMPOSITIONS OF ENTACAPONE
EP1946756A1 (en) *	2007-01-17	2008-07-23	Revotar Biopharmaceuticals AG	Use of entacapone in cosmetic, dermatological and pharmaceutical compositions
PL2252284T3 (pl) *	2008-02-06	2011-10-31	Wockhardt Ltd	Kompozycja farmaceutyczna entakaponu, lewodopy i karbidopy o poprawionej dostępności biologicznej
NZ587169A (en) *	2008-02-06	2011-03-31	Wockhardt Research Center	Pharmaceutical compositions of entacapone co-micronized with sugar alcohols
KR101667762B1 (ko) *	2008-08-22	2016-10-20	욱크하르트 리미티드	엔타카폰 또는 이의 염의 서방형 약학 조성물
TR200806646A2 (tr) *	2008-09-03	2009-06-22	Dr. F. Fri̇k İlaç San. Ve Ti̇c. A.Ş.	Entakapon, levodopa ve karbidoba içeren farmasötik kombinasyonlar
US20130137729A1 (en) *	2010-03-04	2013-05-30	Orion Corporation	Use of levodopa, carbidopa and entacapone for treating parkinson's disease
DE102010023828A1 (de) *	2010-06-15	2011-12-15	IIP - Institut für industrielle Pharmazie, Forschungs- und Entwicklungsgesellschaft mbH	Pharmazeutisches Präparat, welches Entacapon, Levodopa und Carbidopa enthält
US8263119B2 (en) *	2010-12-01	2012-09-11	Shire Llc	Capsule formulations containing lanthanum compounds
AU2011366717B2 (en) *	2011-04-26	2017-06-15	Innopharmax Inc	A composition of entacopone
CN103845318A (zh) *	2012-12-07	2014-06-11	天津市汉康医药生物技术有限公司	恩他卡朋分散片
BR112015022390A8 (pt) *	2013-03-13	2019-11-26	Neuroderm Ltd	uso de carbidopa, levodopa e um inibidor de comt para a preparação de uma composição para tratamento de doença de parkinson
HUE052642T2 (hu)	2014-03-13	2021-05-28	Neuroderm Ltd	DOPA dekarboxiláz inhibitor készítmények
US10258585B2 (en)	2014-03-13	2019-04-16	Neuroderm, Ltd.	DOPA decarboxylase inhibitor compositions
RU2017120184A (ru)	2014-11-28	2018-12-28	БИАЛ - ПОРТЕЛА ЭНД Ка, С.А.	Лекарства для замедления течения болезни паркинсона
JP6411265B2 (ja) *	2015-03-30	2018-10-24	共和薬品工業株式会社	エンタカポン含有医薬組成物
BR112017016393A2 (pt) *	2015-05-08	2018-03-27	Wockhardt Limited	composições farmacêuticas estáveis compreendendo agente antibacteriano
WO2017028814A1 (en) *	2015-08-20	2017-02-23	Tsh Biopharm Corporation Ltd.	Pharmaceutical composition comprising amlodipine and dextromethorphan
EP3275433A1 (en) *	2016-07-29	2018-01-31	Som Innovation Biotech S.L.	Sustained release composition comprising micronized tolcapone
WO2018034626A1 (en) *	2016-08-18	2018-02-22	İlko İlaç Sanayi Ve Ticaret Anonim Şirketi	Antiparkinson tablet formulation with improved dissolution profile
CN106236720A (zh) *	2016-08-29	2016-12-21	海南通用康力制药有限公司	一种恩他卡朋的药物组合物及其制备方法
TWI595871B (zh) *	2016-09-22	2017-08-21	生達化學製藥股份有限公司	含有兒茶酚－ｏ－甲基轉移酶抑制劑之口服醫藥組成物及其製造方法
US11213502B1 (en)	2020-11-17	2022-01-04	Neuroderm, Ltd.	Method for treatment of parkinson's disease
US11331293B1 (en)	2020-11-17	2022-05-17	Neuroderm, Ltd.	Method for treatment of Parkinson's disease
US11844754B2 (en)	2020-11-17	2023-12-19	Neuroderm, Ltd.	Methods for treatment of Parkinson's disease
WO2022180649A1 (en) *	2021-02-26	2022-09-01	Msn Laboratories Private Limited, R&D Center	Novel process for the preparation of 2,5-dichloro-3-(5-(3,4-dihydroxy-5-nitrophenyl)-1,2,4-oxadiazol-3-yl)-4,6-dimethylpyridine-1-oxide
CN113274362A (zh) *	2021-03-31	2021-08-20	海南通用康力制药有限公司	恩他卡朋片的生产方法
US12161612B2 (en)	2023-04-14	2024-12-10	Neuroderm, Ltd.	Methods and compositions for reducing symptoms of Parkinson's disease

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US5283352A (en)	1986-11-28	1994-02-01	Orion-Yhtyma Oy	Pharmacologically active compounds, methods for the preparation thereof and compositions containing the same
GB2238047B (en)	1989-11-03	1993-02-10	Orion Yhtymae Oy	Stable polymorphic form of (e)-n,n-diethyl-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)acrylamide and the process for its preparation
US5429825A (en) *	1992-06-26	1995-07-04	Mcneil-Ppc, Inc.	Rotomelt granulation
FI101039B (fi) *	1992-10-09	1998-04-15	Eeva Kristoffersson	Menetelmä lääkepellettien valmistamiseksi
US5562291A (en) *	1995-09-28	1996-10-08	Daniel D. Garcia	Arrow tip for shooting wooden target
US5952509A (en) *	1996-06-27	1999-09-14	Takeda Chemical Industries, Ltd.	Production of benzaldehyde compounds
US5965571A (en) *	1996-08-22	1999-10-12	New York University	Cholinesterase inhibitors for treatment of Parkinson's disease
US6599530B2 (en) *	1998-09-14	2003-07-29	Orion Corporation	Oral compacted composition comprising catechol derivatives
US20080118556A1 (en) *	1998-11-02	2008-05-22	Elan Corporation, Plc	Modified Release of Compositions Containing a Combination of Carbidopa, Levodopa and Entacapone
US7374779B2 (en) *	1999-02-26	2008-05-20	Lipocine, Inc.	Pharmaceutical formulations and systems for improved absorption and multistage release of active agents
FI109453B (fi) *	1999-06-30	2002-08-15	Orion Yhtymae Oyj	Farmaseuttinen koostumus
MXPA04007427A (es) *	2002-02-01	2004-10-11	Pfizer Prod Inc	Formulaciones de azitromicina granuladas por via seca.
US20040166159A1 (en) *	2002-05-29	2004-08-26	Chien-Hsuan Han	Pharmaceutical dosage forms having immediate and controlled release properties that contain an aromatic amino acid decarboxylase inhibitor and levodopa
WO2005063696A2 (de)	2003-12-31	2005-07-14	Cilag Ag	Neue kristalline formen von entacapone und deren herstellung
US20060222703A1 (en) *	2005-04-01	2006-10-05	Iprbox Oy	Pharmaceutical composition and preparation method thereof
DE602006018529D1 (de) *	2005-12-29	2011-01-05	Osmotica Kereskedelmi Es Szolgaltato Kft	Mehrschichtige tablette mit dreifacher freisetzungskombination
US20090155369A1 (en) *	2007-12-13	2009-06-18	Laboratorios Lesvi, S.L.	Pharmaceutical composition containing levodopa, entacapone and carbidopa

2006
- 2006-06-07 WO PCT/FI2006/000182 patent/WO2006131591A2/en active Application Filing
- 2006-06-07 PT PT06755404T patent/PT1896006E/pt unknown
- 2006-06-07 EP EP06755404A patent/EP1896006B1/en not_active Revoked
- 2006-06-07 EP EP10011644A patent/EP2335696A1/en not_active Withdrawn
- 2006-06-07 AT AT06755404T patent/ATE444746T1/de active
- 2006-06-07 CA CA2611114A patent/CA2611114C/en active Active
- 2006-06-07 EA EA200702616A patent/EA013161B1/ru not_active IP Right Cessation
- 2006-06-07 EP EP10011645A patent/EP2316448A1/en not_active Withdrawn
- 2006-06-07 EP EP10011858A patent/EP2308487A1/en not_active Withdrawn
- 2006-06-07 US US11/916,460 patent/US20080187590A1/en not_active Abandoned
- 2006-06-07 SI SI200630519T patent/SI1896006T1/sl unknown
- 2006-06-07 PL PL06755404T patent/PL1896006T3/pl unknown
- 2006-06-07 ES ES06755404T patent/ES2311442T3/es active Active
- 2006-06-07 DK DK06755404T patent/DK1896006T3/da active
- 2006-06-07 KR KR1020147032488A patent/KR101617990B1/ko active IP Right Grant
- 2006-06-07 CN CN2006800187628A patent/CN101184483B/zh not_active Ceased
- 2006-06-07 EP EP09000405.2A patent/EP2050447B1/en active Active
- 2006-06-07 PT PT90004052T patent/PT2050447T/pt unknown
- 2006-06-07 MX MX2007015377A patent/MX2007015377A/es active IP Right Grant
- 2006-06-07 JP JP2008515235A patent/JP5336181B2/ja active Active
- 2006-06-07 AU AU2006256724A patent/AU2006256724B2/en active Active
- 2006-06-07 DE DE602006009652T patent/DE602006009652D1/de active Active
2007
- 2007-12-06 KR KR1020077028533A patent/KR101468738B1/ko active IP Right Grant
- 2007-12-28 NO NO20076687A patent/NO345046B1/no unknown
2009
- 2009-12-11 CY CY20091101296T patent/CY1109587T1/el unknown
2011
- 2011-11-11 US US13/294,209 patent/US20120289594A1/en not_active Abandoned
2013
- 2013-04-10 JP JP2013082320A patent/JP2013173760A/ja active Pending
- 2013-06-06 US US13/911,185 patent/US20130274330A1/en not_active Abandoned

Also Published As

Publication number	Publication date
EP2050447B1 (en)	2017-10-11
DK1896006T3 (da)	2009-12-07
KR20150001843A (ko)	2015-01-06
KR20080012945A (ko)	2008-02-12
AU2006256724B2 (en)	2012-06-07
NO20076687L (no)	2007-12-28
US20130274330A1 (en)	2013-10-17
WO2006131591A2 (en)	2006-12-14
PT2050447T (pt)	2018-01-17
PL1896006T3 (pl)	2010-03-31
JP5336181B2 (ja)	2013-11-06
EA013161B1 (ru)	2010-02-26
EP2308487A1 (en)	2011-04-13
US20120289594A1 (en)	2012-11-15
EP1896006B1 (en)	2009-10-07
EP2335696A1 (en)	2011-06-22
WO2006131591A3 (en)	2007-03-01
PT1896006E (pt)	2009-10-19
ES2311442T1 (es)	2009-02-16
KR101468738B1 (ko)	2014-12-03
EP2316448A1 (en)	2011-05-04
ES2311442T3 (es)	2010-01-07
ATE444746T1 (de)	2009-10-15
JP2008542434A (ja)	2008-11-27
EP2050447A1 (en)	2009-04-22
AU2006256724A1 (en)	2006-12-14
MX2007015377A (es)	2008-02-14
EA200702616A1 (ru)	2008-04-28
CN101184483B (zh)	2011-08-10
CN101184483A (zh)	2008-05-21
DE602006009652D1 (de)	2009-11-19
EP1896006A2 (en)	2008-03-12
JP2013173760A (ja)	2013-09-05
CA2611114C (en)	2014-09-23
KR101617990B1 (ko)	2016-05-03
US20080187590A1 (en)	2008-08-07
CY1109587T1 (el)	2014-08-13
CA2611114A1 (en)	2006-12-14
NO345046B1 (no)	2020-09-07

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PL1896006T3 (pl)	2010-03-31	Sposób wytwarzania granulek zawierających entakapon do postaci dawkowania doustnego
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