SI1578350T1 - Z gelom obloženi sestavki z zadržanim sproščanjem - Google Patents
Z gelom obloženi sestavki z zadržanim sproščanjemInfo
- Publication number
- SI1578350T1 SI1578350T1 SI200331641T SI200331641T SI1578350T1 SI 1578350 T1 SI1578350 T1 SI 1578350T1 SI 200331641 T SI200331641 T SI 200331641T SI 200331641 T SI200331641 T SI 200331641T SI 1578350 T1 SI1578350 T1 SI 1578350T1
- Authority
- SI
- Slovenia
- Prior art keywords
- sustained
- gel coated
- release gel
- coated compositions
- compositions
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 2
- 238000013268 sustained release Methods 0.000 title 1
- 239000012730 sustained-release form Substances 0.000 title 1
- 108010010803 Gelatin Proteins 0.000 abstract 1
- 239000011248 coating agent Substances 0.000 abstract 1
- 238000000576 coating method Methods 0.000 abstract 1
- 229920000159 gelatin Polymers 0.000 abstract 1
- 239000008273 gelatin Substances 0.000 abstract 1
- 235000019322 gelatine Nutrition 0.000 abstract 1
- 235000011852 gelatine desserts Nutrition 0.000 abstract 1
- 229920001600 hydrophobic polymer Polymers 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1658—Proteins, e.g. albumin, gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/2873—Proteins, e.g. gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
- A61K9/2846—Poly(meth)acrylates
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Addiction (AREA)
- Neurology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
- Paints Or Removers (AREA)
- Materials For Medical Uses (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US36783202P | 2002-03-26 | 2002-03-26 | |
PCT/US2003/009420 WO2003082204A2 (en) | 2002-03-26 | 2003-03-26 | Sustained-release gel coated compositions |
EP03716865A EP1578350B1 (en) | 2002-03-26 | 2003-03-26 | Sustained-release gel coated compositions |
Publications (1)
Publication Number | Publication Date |
---|---|
SI1578350T1 true SI1578350T1 (sl) | 2009-10-31 |
Family
ID=28675409
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SI200331641T SI1578350T1 (sl) | 2002-03-26 | 2003-03-26 | Z gelom obloženi sestavki z zadržanim sproščanjem |
Country Status (12)
Country | Link |
---|---|
US (1) | US7790215B2 (sl) |
EP (1) | EP1578350B1 (sl) |
JP (2) | JP4790219B2 (sl) |
AT (1) | ATE432065T1 (sl) |
AU (1) | AU2003220551A1 (sl) |
CY (1) | CY1109332T1 (sl) |
DE (1) | DE60327807D1 (sl) |
DK (1) | DK1578350T3 (sl) |
ES (1) | ES2327034T3 (sl) |
PT (1) | PT1578350E (sl) |
SI (1) | SI1578350T1 (sl) |
WO (1) | WO2003082204A2 (sl) |
Families Citing this family (75)
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EP2295043A1 (en) | 1999-10-29 | 2011-03-16 | Euro-Celtique S.A. | Controlled release hydrocodone formulations |
US10179130B2 (en) | 1999-10-29 | 2019-01-15 | Purdue Pharma L.P. | Controlled release hydrocodone formulations |
EP2283842B1 (en) | 2000-02-08 | 2015-03-25 | Euro-Celtique S.A. | Tamper-resistant oral opioid agonist formulations |
US6733783B2 (en) | 2000-10-30 | 2004-05-11 | Euro-Celtique S.A. | Controlled release hydrocodone formulations |
EP1404331B1 (en) | 2001-07-06 | 2007-10-31 | Penwest Pharmaceuticals Co. | Sustained release formulations of oxymorphone |
WO2003004032A1 (en) | 2001-07-06 | 2003-01-16 | Endo Pharmaceuticals, Inc. | Oral administration of 6-hydroxy-oxymorphone for use as an analgesic |
US8329216B2 (en) | 2001-07-06 | 2012-12-11 | Endo Pharmaceuticals Inc. | Oxymorphone controlled release formulations |
WO2003013433A2 (en) | 2001-08-06 | 2003-02-20 | Euro-Celtique S.A. | Sequestered antagonist formulations |
US20040253310A1 (en) | 2001-09-21 | 2004-12-16 | Gina Fischer | Morphine polymer release system |
EP2957281A1 (en) | 2001-09-21 | 2015-12-23 | Egalet Ltd. | Polymer release system |
WO2003026628A2 (en) | 2001-09-28 | 2003-04-03 | Mcneil-Ppc, Inc. | Composite dosage forms having an inlaid portion |
US7906145B2 (en) | 2002-04-09 | 2011-03-15 | Flamel Technologies | Oral pharmaceutical formulation in the form of aqueous suspension for modified release of active principle(s) |
SI1551372T1 (sl) * | 2002-09-20 | 2018-08-31 | Alpharma Pharmaceuticals Llc | Podenota za sekvestriranje in z njo povezani sestavki in postopki |
WO2004084868A1 (en) | 2003-03-26 | 2004-10-07 | Egalet A/S | Morphine controlled release system |
US20040202717A1 (en) | 2003-04-08 | 2004-10-14 | Mehta Atul M. | Abuse-resistant oral dosage forms and method of use thereof |
TWI347201B (en) * | 2003-04-21 | 2011-08-21 | Euro Celtique Sa | Pharmaceutical products,uses thereof and methods for preparing the same |
JP5501553B2 (ja) | 2003-04-21 | 2014-05-21 | ユーロ−セルティーク エス.エイ. | 同時押出逆作用剤粒子を含有する改変防止剤形およびその製造工程 |
US8168228B2 (en) * | 2003-10-17 | 2012-05-01 | Sandoz Ag | Antibiotic clarithromycin micropellet compositions |
US8883204B2 (en) * | 2003-12-09 | 2014-11-11 | Purdue Pharma L.P. | Tamper resistant co-extruded dosage form containing an active agent and an adverse agent and process of making same |
TWI483944B (zh) | 2004-03-30 | 2015-05-11 | Euro Celtique Sa | 含有小於25ppm14-羥可待因酮之羥可酮鹽酸鹽組成物、醫藥劑型、延遲釋出口服劑型及醫藥上可以接受的包裝 |
JP2007532645A (ja) * | 2004-04-13 | 2007-11-15 | アルザ コーポレイション | フェンタニルに基づく薬剤の経皮送達システム用の器具および方法 |
ITMI20041317A1 (it) * | 2004-06-30 | 2004-09-30 | Ibsa Inst Biochimique Sa | Formulazioni farmaceutiche per la somministrazione sicura di farmaci utilizzati nel trattamento della tossicodipendenza e procedimento per il loro ottenimento |
EA200702221A1 (ru) * | 2005-04-12 | 2008-04-28 | Элан Фарма Интернэшнл Лимитед | Композиции с контролируемым высвобождением для лечения бактериальной инфекции, содержащие цефалоспорин |
US8673352B2 (en) | 2005-04-15 | 2014-03-18 | Mcneil-Ppc, Inc. | Modified release dosage form |
WO2009023006A2 (en) * | 2006-05-08 | 2009-02-19 | Mcneil-Ppc, Inc. | Modified release dosage form |
CA2612727A1 (en) * | 2005-05-13 | 2006-11-23 | Alpharma, Inc. | Morphine sulfate formulations |
JP5161075B2 (ja) * | 2005-06-03 | 2013-03-13 | エガレット エイ/エス | 分散媒体の第1フラクションとマトリックスの第2フラクションを有し、第2フラクションが胃腸の液体に少なくとも部分的に最初に曝される固形の医薬組成物 |
WO2006133733A1 (en) | 2005-06-13 | 2006-12-21 | Flamel Technologies | Oral dosage form comprising an antimisuse system |
US8652529B2 (en) | 2005-11-10 | 2014-02-18 | Flamel Technologies | Anti-misuse microparticulate oral pharmaceutical form |
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US8623418B2 (en) | 2007-12-17 | 2014-01-07 | Alpharma Pharmaceuticals Llc | Pharmaceutical composition |
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DE102008021473A1 (de) * | 2008-04-29 | 2009-11-12 | Heraeus Kulzer Gmbh | Mit Antiplaque-Wirkstoff(en) ausgestattete Dentalmaterialien |
DE102008047910A1 (de) | 2008-09-19 | 2010-03-25 | Molkerei Meggle Wasserburg Gmbh & Co. Kg | Tablettierhilfsstoff auf Laktose- und Cellulosebasis |
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WO2010103365A2 (en) * | 2009-03-09 | 2010-09-16 | Council Of Scientific & Industrial Research | Sustained release composition of therapeutic agent |
WO2010103367A1 (en) * | 2009-03-09 | 2010-09-16 | Council Of Scientific & Industrial Research | Pulsatile release composition of therapeutic agent |
EP2445487A2 (en) | 2009-06-24 | 2012-05-02 | Egalet Ltd. | Controlled release formulations |
PH12013501345A1 (en) * | 2010-12-23 | 2022-10-24 | Purdue Pharma Lp | Tamper resistant solid oral dosage forms |
ES2673286T3 (es) | 2011-02-11 | 2018-06-21 | Zx Pharma, Llc | Formulaciones multiparticuladas de L-mentol y métodos relacionados |
US8808736B2 (en) | 2011-02-11 | 2014-08-19 | Zx Pharma, Llc | Enteric coated multiparticulate controlled release peppermint oil composition and related methods |
US8911780B2 (en) | 2011-02-11 | 2014-12-16 | Zx Pharma, Llc | Multiparticulate L-menthol formulations and related methods |
EP2606879A1 (en) * | 2011-12-21 | 2013-06-26 | Hexal AG | Multiple unit pellet tablet formulation comprising an opioid |
KR20150059167A (ko) | 2012-07-06 | 2015-05-29 | 에갈렛 리미티드 | 제어된 방출을 위한 남용 제지 약학적 조성물 |
US10322120B2 (en) | 2012-07-31 | 2019-06-18 | Persion Pharmaceuticals Llc | Treating pain in patients with hepatic impairment |
US20140161879A1 (en) * | 2012-07-31 | 2014-06-12 | Zogenix, Inc. | Treating pain in patients with hepatic impairment |
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CA2795324C (en) * | 2012-11-09 | 2015-07-14 | Purdue Pharma | Pharmaceutical compositions comprising hydromorphone and naloxone |
US10751287B2 (en) | 2013-03-15 | 2020-08-25 | Purdue Pharma L.P. | Tamper resistant pharmaceutical formulations |
ES2706152T3 (es) | 2013-04-23 | 2019-03-27 | Zx Pharma Llc | Composición entérica de múltiples partículas revestida con subrevestimiento proteico |
WO2015023675A2 (en) | 2013-08-12 | 2015-02-19 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded immediate release abuse deterrent pill |
US9770514B2 (en) | 2013-09-03 | 2017-09-26 | ExxPharma Therapeutics LLC | Tamper-resistant pharmaceutical dosage forms |
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JP2017531026A (ja) | 2014-10-20 | 2017-10-19 | ファーマシューティカル マニュファクチュアリング リサーチ サービシズ,インコーポレーテッド | 徐放性乱用抑止性液体充填剤形 |
US9861629B1 (en) | 2015-10-07 | 2018-01-09 | Banner Life Sciences Llc | Opioid abuse deterrent dosage forms |
US20170119680A1 (en) | 2015-10-30 | 2017-05-04 | R.P. Scherer Technologies, Llc | Extended release film-coated capsules |
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US12303604B1 (en) | 2024-10-16 | 2025-05-20 | Currax Pharmaceuticals Llc | Pharmaceutical formulations comprising naltrexone and/or bupropion |
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DE2340060A1 (de) | 1973-08-08 | 1975-02-20 | Scherer Gmbh R P | Magensaftresistente gelatinekapseln und verfahren zu deren herstellung |
JPS5843137B2 (ja) | 1974-04-09 | 1983-09-24 | 富士写真フイルム株式会社 | カプセルカホウホウ |
JPS55136061A (en) | 1979-04-12 | 1980-10-23 | Freunt Ind Co Ltd | Sheath capsule |
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EP2283842B1 (en) * | 2000-02-08 | 2015-03-25 | Euro-Celtique S.A. | Tamper-resistant oral opioid agonist formulations |
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-
2003
- 2003-03-26 ES ES03716865T patent/ES2327034T3/es not_active Expired - Lifetime
- 2003-03-26 DK DK03716865T patent/DK1578350T3/da active
- 2003-03-26 AU AU2003220551A patent/AU2003220551A1/en not_active Abandoned
- 2003-03-26 SI SI200331641T patent/SI1578350T1/sl unknown
- 2003-03-26 PT PT03716865T patent/PT1578350E/pt unknown
- 2003-03-26 WO PCT/US2003/009420 patent/WO2003082204A2/en active Application Filing
- 2003-03-26 EP EP03716865A patent/EP1578350B1/en not_active Expired - Lifetime
- 2003-03-26 JP JP2003579747A patent/JP4790219B2/ja not_active Expired - Fee Related
- 2003-03-26 AT AT03716865T patent/ATE432065T1/de active
- 2003-03-26 DE DE60327807T patent/DE60327807D1/de not_active Expired - Lifetime
- 2003-03-26 US US10/401,111 patent/US7790215B2/en active Active
-
2009
- 2009-08-24 CY CY20091100892T patent/CY1109332T1/el unknown
-
2011
- 2011-06-06 JP JP2011125956A patent/JP5323134B2/ja not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
ES2327034T3 (es) | 2009-10-23 |
EP1578350A2 (en) | 2005-09-28 |
AU2003220551A8 (en) | 2003-10-13 |
EP1578350B1 (en) | 2009-05-27 |
DK1578350T3 (da) | 2009-08-10 |
WO2003082204A3 (en) | 2007-12-21 |
AU2003220551A1 (en) | 2003-10-13 |
ATE432065T1 (de) | 2009-06-15 |
US20030190362A1 (en) | 2003-10-09 |
WO2003082204A2 (en) | 2003-10-09 |
US7790215B2 (en) | 2010-09-07 |
EP1578350A4 (en) | 2006-03-22 |
JP2006508021A (ja) | 2006-03-09 |
PT1578350E (pt) | 2009-08-27 |
JP5323134B2 (ja) | 2013-10-23 |
DE60327807D1 (de) | 2009-07-09 |
CY1109332T1 (el) | 2014-07-02 |
JP4790219B2 (ja) | 2011-10-12 |
JP2011201912A (ja) | 2011-10-13 |
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