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FR2892937B1 - Forme pharmaceutique orale microparticulaire anti-mesusage - Google Patents

Forme pharmaceutique orale microparticulaire anti-mesusage

Info

Publication number
FR2892937B1
FR2892937B1 FR0553437A FR0553437A FR2892937B1 FR 2892937 B1 FR2892937 B1 FR 2892937B1 FR 0553437 A FR0553437 A FR 0553437A FR 0553437 A FR0553437 A FR 0553437A FR 2892937 B1 FR2892937 B1 FR 2892937B1
Authority
FR
France
Prior art keywords
microparticular
measuring
oral pharmaceutical
pharmaceutical form
form anti
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
FR0553437A
Other languages
English (en)
Other versions
FR2892937A1 (fr
Inventor
Florence Guimberteau
Frederic Dargelas
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Flamel Ireland Ltd
Original Assignee
Flamel Technologies SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR0553437A priority Critical patent/FR2892937B1/fr
Application filed by Flamel Technologies SA filed Critical Flamel Technologies SA
Priority to JP2008539368A priority patent/JP5537030B2/ja
Priority to EP06763289A priority patent/EP1945230A1/fr
Priority to AU2006311116A priority patent/AU2006311116C1/en
Priority to MX2008006042A priority patent/MX2008006042A/es
Priority to BRPI0618502-9A priority patent/BRPI0618502A2/pt
Priority to KR1020147014471A priority patent/KR20140090222A/ko
Priority to CNA2006800422365A priority patent/CN101304752A/zh
Priority to PCT/EP2006/062627 priority patent/WO2007054378A1/fr
Priority to CA002627058A priority patent/CA2627058A1/fr
Priority to KR1020087013970A priority patent/KR101425196B1/ko
Priority to US11/439,432 priority patent/US8652529B2/en
Publication of FR2892937A1 publication Critical patent/FR2892937A1/fr
Priority to IL190749A priority patent/IL190749A/en
Priority to ZA200803140A priority patent/ZA200803140B/xx
Priority to US12/638,739 priority patent/US8445023B2/en
Application granted granted Critical
Publication of FR2892937B1 publication Critical patent/FR2892937B1/fr
Priority to US14/081,038 priority patent/US20140072644A1/en
Priority to IL233925A priority patent/IL233925A/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • A61K31/785Polymers containing nitrogen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5021Organic macromolecular compounds
    • A61K9/5036Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10Laxatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/14Antitussive agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Child & Adolescent Psychology (AREA)
  • Hematology (AREA)
  • Rheumatology (AREA)
  • Anesthesiology (AREA)
  • Psychology (AREA)
  • Psychiatry (AREA)
  • Pulmonology (AREA)
  • Obesity (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FR0553437A 2005-11-10 2005-11-10 Forme pharmaceutique orale microparticulaire anti-mesusage Active FR2892937B1 (fr)

Priority Applications (17)

Application Number Priority Date Filing Date Title
FR0553437A FR2892937B1 (fr) 2005-11-10 2005-11-10 Forme pharmaceutique orale microparticulaire anti-mesusage
CA002627058A CA2627058A1 (fr) 2005-11-10 2006-05-24 Forme pharmaceutique orale microparticulaire anti-mesusage
AU2006311116A AU2006311116C1 (en) 2005-11-10 2006-05-24 Anti-misuse microparticulate oral pharmaceutical form
MX2008006042A MX2008006042A (es) 2005-11-10 2006-05-24 Forma farmaceutica oral de microparticulado anti-mal uso.
BRPI0618502-9A BRPI0618502A2 (pt) 2005-11-10 2006-05-24 forma farmacêutica oral de micropartìculas contra mau uso
KR1020147014471A KR20140090222A (ko) 2005-11-10 2006-05-24 오용 방지 극미립자 경구 약학 제형
CNA2006800422365A CN101304752A (zh) 2005-11-10 2006-05-24 防滥用的微粒口服药物形式
PCT/EP2006/062627 WO2007054378A1 (fr) 2005-11-10 2006-05-24 Forme pharmaceutique orale microparticulaire anti-mesusage
JP2008539368A JP5537030B2 (ja) 2005-11-10 2006-05-24 誤用防止微粒子経口医薬形態
KR1020087013970A KR101425196B1 (ko) 2005-11-10 2006-05-24 오용 방지 극미립자 경구 약학 제형
US11/439,432 US8652529B2 (en) 2005-11-10 2006-05-24 Anti-misuse microparticulate oral pharmaceutical form
EP06763289A EP1945230A1 (fr) 2005-11-10 2006-05-24 Forme pharmaceutique orale microparticulaire anti-mesusage
IL190749A IL190749A (en) 2005-11-10 2008-04-09 Pharmaceutical dose for oral administration in the form of tiny particles to prevent misuse
ZA200803140A ZA200803140B (en) 2005-11-10 2008-04-09 Anti-misuse microparticulate oral pharmaceutical form
US12/638,739 US8445023B2 (en) 2005-11-10 2009-12-15 Anti-misuse microparticulate oral pharmaceutical form
US14/081,038 US20140072644A1 (en) 2005-11-10 2013-11-15 Anti-misuse microparticulate oral pharmaceutical form
IL233925A IL233925A (en) 2005-11-10 2014-08-03 Pharmaceutical dose for oral administration in the form of tiny particles to prevent misuse

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0553437A FR2892937B1 (fr) 2005-11-10 2005-11-10 Forme pharmaceutique orale microparticulaire anti-mesusage

Publications (2)

Publication Number Publication Date
FR2892937A1 FR2892937A1 (fr) 2007-05-11
FR2892937B1 true FR2892937B1 (fr) 2013-04-05

Family

ID=36930690

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0553437A Active FR2892937B1 (fr) 2005-11-10 2005-11-10 Forme pharmaceutique orale microparticulaire anti-mesusage

Country Status (12)

Country Link
EP (1) EP1945230A1 (fr)
JP (1) JP5537030B2 (fr)
KR (2) KR20140090222A (fr)
CN (1) CN101304752A (fr)
AU (1) AU2006311116C1 (fr)
BR (1) BRPI0618502A2 (fr)
CA (1) CA2627058A1 (fr)
FR (1) FR2892937B1 (fr)
IL (2) IL190749A (fr)
MX (1) MX2008006042A (fr)
WO (1) WO2007054378A1 (fr)
ZA (1) ZA200803140B (fr)

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FR2878161B1 (fr) * 2004-11-23 2008-10-31 Flamel Technologies Sa Forme medicamenteuse orale, solide et concue pour eviter le mesusage
FR2878158B1 (fr) * 2004-11-24 2009-01-16 Flamel Technologies Sa Forme pharmaceutique orale, microparticulaire solide concue pour eviter le mesusage
FR2889810A1 (fr) * 2005-05-24 2007-02-23 Flamel Technologies Sa Forme medicamenteuse orale, microparticulaire, anti-mesurage
FR2881652B1 (fr) * 2005-02-08 2007-05-25 Flamel Technologies Sa Forme pharmaceutique orale microparticulaire anti-mesuage
WO2006133733A1 (fr) * 2005-06-13 2006-12-21 Flamel Technologies Forme posologique orale comportant un systeme anti-abus

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IL190749A (en) 2015-07-30
KR101425196B1 (ko) 2014-08-12
CN101304752A (zh) 2008-11-12
JP2009537456A (ja) 2009-10-29
AU2006311116C1 (en) 2013-10-24
AU2006311116B2 (en) 2013-01-31
IL190749A0 (en) 2008-12-29
WO2007054378A1 (fr) 2007-05-18
KR20140090222A (ko) 2014-07-16
KR20080064905A (ko) 2008-07-09
ZA200803140B (en) 2009-08-26
IL233925A (en) 2017-12-31
AU2006311116A1 (en) 2007-05-18
FR2892937A1 (fr) 2007-05-11
JP5537030B2 (ja) 2014-07-02
IL233925A0 (en) 2014-09-30
CA2627058A1 (fr) 2007-05-18
EP1945230A1 (fr) 2008-07-23
BRPI0618502A2 (pt) 2011-09-06
MX2008006042A (es) 2008-10-01

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