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SI1526856T1 - Farmacevtski sestavek, ki obsega estetrolne derivate za uporabo pri zdravljenju raka - Google Patents

Farmacevtski sestavek, ki obsega estetrolne derivate za uporabo pri zdravljenju raka

Info

Publication number
SI1526856T1
SI1526856T1 SI200331093T SI200331093T SI1526856T1 SI 1526856 T1 SI1526856 T1 SI 1526856T1 SI 200331093 T SI200331093 T SI 200331093T SI 200331093 T SI200331093 T SI 200331093T SI 1526856 T1 SI1526856 T1 SI 1526856T1
Authority
SI
Slovenia
Prior art keywords
pharmaceutical composition
cancer therapy
estetrol
derivatives
estetrol derivatives
Prior art date
Application number
SI200331093T
Other languages
English (en)
Inventor
Bennink Herman Jan Ti Coelingh
Evert Johannes Bunschoten
Original Assignee
Pantarhei Bioscience Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pantarhei Bioscience Bv filed Critical Pantarhei Bioscience Bv
Publication of SI1526856T1 publication Critical patent/SI1526856T1/sl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4196—1,2,4-Triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SI200331093T 2002-07-12 2003-07-11 Farmacevtski sestavek, ki obsega estetrolne derivate za uporabo pri zdravljenju raka SI1526856T1 (sl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP02077812 2002-07-12
EP03075435 2003-02-14
PCT/NL2003/000513 WO2004006936A1 (en) 2002-07-12 2003-07-11 Pharmaceutical composition comprising estetrol derivatives for use in cancer therapy
EP03764245A EP1526856B1 (en) 2002-07-12 2003-07-11 Pharmaceutical composition comprising estetrol derivatives for use in cancer therapy

Publications (1)

Publication Number Publication Date
SI1526856T1 true SI1526856T1 (sl) 2008-04-30

Family

ID=30116907

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200331093T SI1526856T1 (sl) 2002-07-12 2003-07-11 Farmacevtski sestavek, ki obsega estetrolne derivate za uporabo pri zdravljenju raka

Country Status (13)

Country Link
US (2) US9034854B2 (sl)
EP (1) EP1526856B1 (sl)
CN (1) CN100374116C (sl)
AT (1) ATE382356T1 (sl)
AU (1) AU2003253506A1 (sl)
CA (1) CA2492287C (sl)
CY (1) CY1107906T1 (sl)
DE (1) DE60318447T2 (sl)
DK (1) DK1526856T3 (sl)
ES (1) ES2299730T3 (sl)
PT (1) PT1526856E (sl)
SI (1) SI1526856T1 (sl)
WO (1) WO2004006936A1 (sl)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1526856B1 (en) * 2002-07-12 2008-01-02 Pantarhei Bioscience B.V. Pharmaceutical composition comprising estetrol derivatives for use in cancer therapy
DE102007032468A1 (de) * 2007-07-10 2009-01-15 Brätter, Christian, Dr. Transdermale Therapeutische Systeme, welche den Wirkstoff Anastrozol enthalten
RU2422915C1 (ru) * 2010-02-12 2011-06-27 Юрий Николаевич Бордюшков Способ торможения пролиферативного процесса в ткани предстательной железы в эксперименте
BR112013030833B1 (pt) 2011-06-01 2019-09-03 Estetra S A processo para a preparação de um composto de fórmula (i) e processo para a preparação de estetrol
DK2714710T3 (en) 2011-06-01 2016-06-27 Estetra Sprl A process for the preparation of intermediates estetrol
EP2383279A1 (en) 2011-07-19 2011-11-02 Pantarhei Bioscience B.V. Process for the preparation of estetrol
WO2013034780A2 (en) 2012-12-20 2013-03-14 Crystal Pharma, S.A.U. Process for the preparation of estetrol and related compounds
JP6254289B2 (ja) 2013-09-18 2017-12-27 クリスタル ファルマ、エセ、ア、ウＣｒｙｓｔａｌ Ｐｈａｒｍａ，Ｓ．Ａ．Ｕ． エステトロールの製造プロセス
CA2988485A1 (en) * 2015-06-18 2016-12-22 Mithra Pharmaceuticals S.A. Orodispersible tablet containing estetrol
PT3701944T (pt) 2015-06-18 2022-01-11 Estetra Srl Dose unitária orodispersível contendo um composto de estetrol
MA44206B1 (fr) * 2015-06-18 2021-04-30 Estetra Sprl Comprimé orodispersible comprenant estetrol
GEP20217308B (en) 2015-06-18 2021-10-25 Estetra Sprl Orodispersible dosage unit containing an estetrol component
CA3178291A1 (en) 2016-08-05 2018-04-12 Estetra Srl Method for the management of dysmenorrhea and menstrual pain
TWI801561B (zh) 2018-04-19 2023-05-11 比利時商依思特拉私人有限責任公司 化合物及其用於緩解絕經相關症狀的用途
JOP20200260A1 (ar) 2018-04-19 2019-10-19 Estetra Sprl مركبات واستخداماتها للتخفيف من الأعراض المصاحبة لانقطاع الطمث
CA3098601A1 (en) * 2018-05-02 2019-11-07 Estetra Sprl Treatment of advanced estrogen receptor positive breast cancer
HU231240B1 (hu) 2019-09-03 2022-04-28 Richter Gedeon Nyrt. Ipari eljárás nagytisztaságú ösztetrol hatóanyag előállítására

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US4722941A (en) 1978-06-07 1988-02-02 Kali-Chemie Pharma Gmbh Readily absorbable pharmaceutical compositions of per se poorly absorbable pharmacologically active agents and preparation thereof
US4460372A (en) 1981-02-17 1984-07-17 Alza Corporation Percutaneous absorption enhancer dispenser for use in coadministering drug and percutaneous absorption enhancer
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US5468736A (en) * 1993-02-25 1995-11-21 The Medical College Of Hampton Road Hormone replacement therapy
US5895783A (en) 1993-07-16 1999-04-20 Schering Aktiengesellschaft Treatment of preeclampsia and preterm labor with combination of progestational agent and a nitric oxide synthase substrate and/or donor
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DE4344405C2 (de) 1993-12-24 1995-12-07 Marika Dr Med Ehrlich Ovulationshemmendes Mittel und Verfahren zur hormonalen Kontrazeption
WO1996003929A1 (en) 1994-08-04 1996-02-15 Biex, Inc. Method for prediction of premature delivery using estetrol (e4) as an indicator
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US6936599B2 (en) 2001-04-25 2005-08-30 The Regents Of The University Of California Estriol therapy for multiple sclerosis and other autoimmune diseases
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EP1526856B1 (en) * 2002-07-12 2008-01-02 Pantarhei Bioscience B.V. Pharmaceutical composition comprising estetrol derivatives for use in cancer therapy
ES2298570T3 (es) * 2002-10-23 2008-05-16 Pantarhei Bioscience B.V. Composiciones farmaceuticas que comprenden derivados de estetrol para el uso en la terapia del cancer.
SI1624878T1 (sl) * 2003-05-22 2007-02-28 Pantarhei Bioscience Bv Uporaba sestavkov, ki obsegajo estrogensko komponento, za zdravljenje in preprecevanje muskuloskeletne bolecine

Also Published As

Publication number Publication date
EP1526856B1 (en) 2008-01-02
DE60318447T2 (de) 2009-01-02
US9034854B2 (en) 2015-05-19
CN100374116C (zh) 2008-03-12
US20060063723A1 (en) 2006-03-23
US20150133413A1 (en) 2015-05-14
US10201611B2 (en) 2019-02-12
AU2003253506A1 (en) 2004-02-02
EP1526856A1 (en) 2005-05-04
WO2004006936A8 (en) 2005-03-03
ATE382356T1 (de) 2008-01-15
ES2299730T3 (es) 2008-06-01
PT1526856E (pt) 2008-04-11
CA2492287A1 (en) 2004-01-22
CY1107906T1 (el) 2013-09-04
CN1681513A (zh) 2005-10-12
CA2492287C (en) 2011-12-13
DE60318447D1 (de) 2008-02-14
DK1526856T3 (da) 2008-03-10
WO2004006936A1 (en) 2004-01-22

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