SI1509517T1 - Nova sinteza irbesartana - Google Patents
Nova sinteza irbesartanaInfo
- Publication number
- SI1509517T1 SI1509517T1 SI200430833T SI200430833T SI1509517T1 SI 1509517 T1 SI1509517 T1 SI 1509517T1 SI 200430833 T SI200430833 T SI 200430833T SI 200430833 T SI200430833 T SI 200430833T SI 1509517 T1 SI1509517 T1 SI 1509517T1
- Authority
- SI
- Slovenia
- Prior art keywords
- irbesartan
- novel synthesis
- synthesis
- novel
- provides
- Prior art date
Links
- 239000002947 C09CA04 - Irbesartan Substances 0.000 title abstract 2
- YCPOHTHPUREGFM-UHFFFAOYSA-N irbesartan Chemical compound O=C1N(CC=2C=CC(=CC=2)C=2C(=CC=CC=2)C=2[N]N=NN=2)C(CCCC)=NC21CCCC2 YCPOHTHPUREGFM-UHFFFAOYSA-N 0.000 title abstract 2
- 229960002198 irbesartan Drugs 0.000 title abstract 2
- 230000015572 biosynthetic process Effects 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Plural Heterocyclic Compounds (AREA)
- Steroid Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Catalysts (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US44099703P | 2003-01-16 | 2003-01-16 | |
PCT/US2004/001135 WO2004065383A2 (en) | 2003-01-16 | 2004-01-16 | Novel synthesis of irbesartan |
EP04702955A EP1509517B1 (en) | 2003-01-16 | 2004-01-16 | Novel synthesis of irbesartan |
Publications (1)
Publication Number | Publication Date |
---|---|
SI1509517T1 true SI1509517T1 (sl) | 2008-10-31 |
Family
ID=32771889
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SI200430833T SI1509517T1 (sl) | 2003-01-16 | 2004-01-16 | Nova sinteza irbesartana |
Country Status (10)
Country | Link |
---|---|
US (6) | US7019148B2 (sl) |
EP (3) | EP2039693A3 (sl) |
CN (2) | CN101165062A (sl) |
AT (1) | ATE398121T1 (sl) |
CA (1) | CA2513373A1 (sl) |
DE (1) | DE602004014321D1 (sl) |
ES (1) | ES2281312T3 (sl) |
PT (1) | PT1509517E (sl) |
SI (1) | SI1509517T1 (sl) |
WO (1) | WO2004065383A2 (sl) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7941149B2 (en) | 2002-05-13 | 2011-05-10 | Misonimo Chi Acquistion L.L.C. | Multi-hop ultra wide band wireless network communication |
US7957356B2 (en) | 2002-05-13 | 2011-06-07 | Misomino Chi Acquisitions L.L.C. | Scalable media access control for multi-hop high bandwidth communications |
US8780770B2 (en) * | 2002-05-13 | 2014-07-15 | Misonimo Chi Acquisition L.L.C. | Systems and methods for voice and video communication over a wireless network |
CN101165062A (zh) * | 2003-01-16 | 2008-04-23 | 特瓦制药工业有限公司 | 伊贝沙坦的新合成方法 |
DE602004015071D1 (de) | 2003-02-05 | 2008-08-28 | Teva Pharma | Synthese von 2-butyl-3-(2'-(1-trityl-1h-tetrazol-5-yl)biphenyl-4-yl)-1,3-diazaspiro-4,4 -nonen-4-on |
EP1751123A4 (en) * | 2004-05-20 | 2010-06-30 | Reddys Lab Ltd Dr | PROCESS FOR PREPARING IRBESARTAN |
TWI346108B (en) * | 2004-08-23 | 2011-08-01 | Bristol Myers Squibb Co | A method for preparing irbesartan and intermediates thereof |
DE102004060699A1 (de) * | 2004-12-16 | 2006-06-22 | Ratiopharm Gmbh | Verfahren zur Herstellung von Candesartan |
PT1833801E (pt) * | 2004-12-22 | 2008-08-25 | Algry Quimica S L | Compostos intermediários para a preparação de antagonistas do receptor da angiotensina ii |
SI21965A (sl) * | 2005-01-05 | 2006-08-31 | Krka, Tovarna Zdravil, D.D., Novo Mesto | Priprava tetrazolskega derivata |
ES2259909B1 (es) * | 2005-02-28 | 2007-06-16 | Inke, S.A. | Procedimiento para la obtencion de un compuesto farmaceuticamente activo y de su intermedio de sintesis. |
WO2006125592A2 (en) * | 2005-05-24 | 2006-11-30 | Lek Pharmaceuticals D.D. | Process for the preparation of 2-alkyl-1-((2'-substituted-biphenyl-4-yl)methyl)-imidazole, dihydroimidazole or benzimidazole derivatives |
EP1749828A1 (en) | 2005-08-04 | 2007-02-07 | Farmaprojects S.L. | Process for preparing an angiotensin II receptor antagonist |
EP1764365A1 (en) * | 2005-09-20 | 2007-03-21 | KRKA, D.D., Novo Mesto | A process for the preparation of sartan derivates and intermediates useful in such process |
EP1948641A1 (en) | 2005-10-28 | 2008-07-30 | Alembic Limited | An improved process for preparation of irbesartan |
ES2300175B1 (es) * | 2006-02-14 | 2009-06-08 | Inke, S.A. | Procedimiento para la obtencion de intermedios utiles en la obtencion de un compuesto farmaceuticamente activo. |
SI2016073T1 (sl) | 2006-04-07 | 2011-12-30 | Lek Pharmaceuticals D.D. | Postopek za pripravo ÄŤistega irbesartana |
US8175613B2 (en) | 2006-08-04 | 2012-05-08 | Misonimo Chi Acquisitions L.L.C. | Systems and methods for determining location of devices within a wireless network |
US20080103312A1 (en) * | 2006-08-29 | 2008-05-01 | Kansal Vinod K | Processes for the synthesis of 5-phenyl-1-trityl-1H-tetrazole |
EP2092664A4 (en) * | 2006-12-07 | 2013-10-16 | Misonimo Chi Acquisition L L C | SYSTEMS AND METHODS FOR TIME WINDOW AND CHANNEL ALLOCATION |
CA2759163C (en) | 2009-04-28 | 2015-02-17 | Daiichi Sankyo Company, Limited | Method for producing olmesartan medoxomil |
CN106608886A (zh) * | 2015-11-22 | 2017-05-03 | 宁夏际华环境安全科技有限公司 | 一种苯基硼酸生产工艺 |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US531929A (en) * | 1895-01-01 | harden | ||
GB8910547D0 (en) * | 1989-05-08 | 1989-06-21 | Ici America Inc | Substituted ketones |
US5270317A (en) | 1990-03-20 | 1993-12-14 | Elf Sanofi | N-substituted heterocyclic derivatives, their preparation and the pharmaceutical compositions in which they are present |
US5164403A (en) * | 1991-04-05 | 1992-11-17 | G. D. Searle & Co. | N-arylheteroarylalkyl imidazol-2-one compounds for treatment of circulatory disorders |
JPH06510763A (ja) * | 1991-08-19 | 1994-12-01 | イー・アイ・デュポン・ドゥ・ヌムール・アンド・カンパニー | アンジオテンシン2受容体遮断イミダゾリノン誘導体 |
US5310929A (en) * | 1992-08-06 | 1994-05-10 | E. I. Du Pont De Nemours And Company | Prodrugs of imidazole carboxylic acids as angiotensin II receptor antagonists |
EP0669830A4 (en) * | 1992-11-06 | 1997-02-26 | Merck & Co Inc | SUBSTITUTED DIPEPTIDE ANALOGS PROMOTING THE RELEASE OF GROWTH HORMONE. |
US5541209A (en) * | 1994-08-22 | 1996-07-30 | Bristol-Myers Squibb Company | Method of treating or preventing cardiac arrhythmia employing an N-substituted heterocyclic derivative |
WO1996009301A1 (fr) * | 1994-09-20 | 1996-03-28 | Wakunaga Seiyaku Kabushiki Kaisha | Procede de production d'un derive de n-biphenylmethylthiadiazoline ou un sel de celui-ci et son intermediaire de production |
FR2725987B1 (fr) | 1994-10-19 | 1997-01-10 | Sanofi Sa | Procede pour la preparation d'un derive de tetrazole sous deux formes cristallines et nouvelle forme cristalline de ce derive |
US5541204A (en) * | 1994-12-02 | 1996-07-30 | Bristol-Myers Squibb Company | Aryloxypropanolamine β 3 adrenergic agonists |
IT1292437B1 (it) * | 1997-06-30 | 1999-02-08 | Zambon Spa | Processo di orto-metallazione utile per la sintesi di 1 - tetrazol- 5-il) benzeni 2-sostituiti |
FR2780403B3 (fr) * | 1998-06-24 | 2000-07-21 | Sanofi Sa | Nouvelle forme de l'irbesartan, procedes pour obtenir ladite forme et compositions pharmaceutiques en contenant |
AU2003256609A1 (en) | 2002-07-16 | 2004-02-02 | Teva Pharmaceutical Industries Ltd. | Novel synthesis of irbesartan |
CN101165062A (zh) * | 2003-01-16 | 2008-04-23 | 特瓦制药工业有限公司 | 伊贝沙坦的新合成方法 |
-
2004
- 2004-01-16 CN CNA2007101866764A patent/CN101165062A/zh active Pending
- 2004-01-16 DE DE602004014321T patent/DE602004014321D1/de not_active Expired - Fee Related
- 2004-01-16 EP EP08010340A patent/EP2039693A3/en not_active Withdrawn
- 2004-01-16 AT AT04702955T patent/ATE398121T1/de not_active IP Right Cessation
- 2004-01-16 CN CNA2004800067788A patent/CN1759113A/zh active Pending
- 2004-01-16 ES ES04702955T patent/ES2281312T3/es not_active Expired - Lifetime
- 2004-01-16 EP EP09180682A patent/EP2189457A1/en not_active Withdrawn
- 2004-01-16 PT PT04702955T patent/PT1509517E/pt unknown
- 2004-01-16 EP EP04702955A patent/EP1509517B1/en not_active Expired - Lifetime
- 2004-01-16 WO PCT/US2004/001135 patent/WO2004065383A2/en active Application Filing
- 2004-01-16 SI SI200430833T patent/SI1509517T1/sl unknown
- 2004-01-16 CA CA002513373A patent/CA2513373A1/en not_active Abandoned
- 2004-01-16 US US10/759,906 patent/US7019148B2/en not_active Expired - Fee Related
-
2006
- 2006-02-06 US US11/348,945 patent/US7217825B2/en not_active Expired - Fee Related
- 2006-02-06 US US11/349,360 patent/US7227026B2/en not_active Expired - Fee Related
- 2006-02-06 US US11/348,944 patent/US7301035B2/en not_active Expired - Fee Related
-
2007
- 2007-05-04 US US11/800,332 patent/US7838683B2/en not_active Expired - Fee Related
-
2008
- 2008-12-18 US US12/317,216 patent/US20090216026A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
CN1759113A (zh) | 2006-04-12 |
WO2004065383A3 (en) | 2004-12-16 |
CN101165062A (zh) | 2008-04-23 |
WO2004065383A2 (en) | 2004-08-05 |
US20060135544A1 (en) | 2006-06-22 |
EP1509517B1 (en) | 2008-06-11 |
US7227026B2 (en) | 2007-06-05 |
US20060128968A1 (en) | 2006-06-15 |
ES2281312T3 (es) | 2008-08-01 |
US7301035B2 (en) | 2007-11-27 |
ES2281312T1 (es) | 2007-10-01 |
EP2039693A3 (en) | 2009-06-17 |
US20090216026A1 (en) | 2009-08-27 |
PT1509517E (pt) | 2008-08-05 |
US7838683B2 (en) | 2010-11-23 |
EP2189457A1 (en) | 2010-05-26 |
EP1509517A2 (en) | 2005-03-02 |
US7019148B2 (en) | 2006-03-28 |
CA2513373A1 (en) | 2004-08-05 |
US20060135780A1 (en) | 2006-06-22 |
DE602004014321D1 (de) | 2008-07-24 |
EP2039693A2 (en) | 2009-03-25 |
US20040192713A1 (en) | 2004-09-30 |
US7217825B2 (en) | 2007-05-15 |
US20070213539A1 (en) | 2007-09-13 |
ATE398121T1 (de) | 2008-07-15 |
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