SI1509244T1 - Nov postopek in spojina za izdelavo celične alogenične vakcine - Google Patents
Nov postopek in spojina za izdelavo celične alogenične vakcineInfo
- Publication number
- SI1509244T1 SI1509244T1 SI200332043T SI200332043T SI1509244T1 SI 1509244 T1 SI1509244 T1 SI 1509244T1 SI 200332043 T SI200332043 T SI 200332043T SI 200332043 T SI200332043 T SI 200332043T SI 1509244 T1 SI1509244 T1 SI 1509244T1
- Authority
- SI
- Slovenia
- Prior art keywords
- apc
- vaccine
- composition
- allogeneic
- producing
- Prior art date
Links
- 229960005486 vaccine Drugs 0.000 title abstract 5
- 230000000735 allogeneic effect Effects 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 4
- 230000001413 cellular effect Effects 0.000 title abstract 2
- 210000004027 cell Anatomy 0.000 abstract 2
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- SQVRNKJHWKZAKO-UHFFFAOYSA-N beta-N-Acetyl-D-neuraminic acid Natural products CC(=O)NC1C(O)CC(O)(C(O)=O)OC1C(O)C(O)CO SQVRNKJHWKZAKO-UHFFFAOYSA-N 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 238000012258 culturing Methods 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 230000004927 fusion Effects 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 238000002955 isolation Methods 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 208000025113 myeloid leukemia Diseases 0.000 abstract 1
- SQVRNKJHWKZAKO-OQPLDHBCSA-N sialic acid Chemical compound CC(=O)N[C@@H]1[C@@H](O)C[C@@](O)(C(O)=O)OC1[C@H](O)[C@H](O)CO SQVRNKJHWKZAKO-OQPLDHBCSA-N 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 238000001890 transfection Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0645—Macrophages, e.g. Kuepfer cells in the liver; Monocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/10—Cellular immunotherapy characterised by the cell type used
- A61K40/17—Monocytes; Macrophages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/20—Cellular immunotherapy characterised by the effect or the function of the cells
- A61K40/24—Antigen-presenting cells [APC]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
- A61K40/41—Vertebrate antigens
- A61K40/42—Cancer antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
- A61K40/41—Vertebrate antigens
- A61K40/42—Cancer antigens
- A61K40/4274—Prostate associated antigens e.g. Prostate stem cell antigen [PSCA]; Prostate carcinoma tumor antigen [PCTA]; Prostatic acid phosphatase [PAP]; Prostate-specific G-protein-coupled receptor [PSGR]
- A61K40/4275—Prostate specific antigen [PSA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
- A61K40/41—Vertebrate antigens
- A61K40/42—Cancer antigens
- A61K40/428—Undefined tumor antigens, e.g. tumor lysate or antigens targeted by cells isolated from tumor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
- A61K2239/46—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterised by the cancer treated
- A61K2239/49—Breast
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
- A61K2239/46—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterised by the cancer treated
- A61K2239/58—Prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/50—Cellular immunotherapy characterised by the use of allogeneic cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/50—Cell markers; Cell surface determinants
- C12N2501/599—Cell markers; Cell surface determinants with CD designations not provided for elsewhere
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/70—Enzymes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Hematology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Oncology (AREA)
- Medicinal Chemistry (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US38589802P | 2002-06-06 | 2002-06-06 | |
| SE0201726A SE523515C2 (sv) | 2002-06-06 | 2002-06-06 | Ny metod och komposition för framställning av ett cellulärt allogent vaccin |
| EP03730977A EP1509244B1 (en) | 2002-06-06 | 2003-06-05 | New method and composition for producing a cellular allogeneic vaccine |
| PCT/SE2003/000936 WO2003103707A1 (en) | 2002-06-06 | 2003-06-05 | New method and composition for producing a cellular allogeneic vaccine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI1509244T1 true SI1509244T1 (sl) | 2011-11-30 |
Family
ID=29738554
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI200332043T SI1509244T1 (sl) | 2002-06-06 | 2003-06-05 | Nov postopek in spojina za izdelavo celične alogenične vakcine |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US20050158328A1 (sl) |
| EP (1) | EP1509244B1 (sl) |
| AT (1) | ATE517633T1 (sl) |
| AU (1) | AU2003241252A1 (sl) |
| DK (1) | DK1509244T3 (sl) |
| ES (1) | ES2369077T3 (sl) |
| SI (1) | SI1509244T1 (sl) |
| WO (1) | WO2003103707A1 (sl) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1712634A1 (en) * | 2005-04-13 | 2006-10-18 | Wittycell SAS | Selection of highly efficient antigen presenting cells for regulating immunity and uses thereof |
| US8563307B2 (en) | 2009-02-24 | 2013-10-22 | James Wang | Treatment of immunosuppression-related disorders |
| SG2014014021A (en) * | 2009-03-24 | 2014-07-30 | Transgene Sa | Biomarker for monitoring patients |
| US8679474B2 (en) | 2010-08-04 | 2014-03-25 | StemBios Technologies, Inc. | Somatic stem cells |
| TWI614340B (zh) | 2011-09-28 | 2018-02-11 | 幹細胞生物科技股份有限公司 | 體幹細胞及其製備方法 |
| CN104822827B (zh) | 2012-12-06 | 2020-01-21 | 干细胞生物科技公司 | Lgr5+体干细胞 |
| AU2013360793B2 (en) | 2012-12-18 | 2019-01-31 | Immunicum Ab | Co-differentiation of monocytes from allogeneic donors |
| EP2746770A1 (en) | 2012-12-21 | 2014-06-25 | Stembios Technologies, Inc. | Method for evaluating effect of action on subject based on stem celldynamics |
| WO2017136633A1 (en) * | 2016-02-04 | 2017-08-10 | Duke University | Cell-based vaccine compositions and methods of use |
| CN106645669B (zh) * | 2016-11-15 | 2018-11-02 | 广东海洋大学 | 一种用于表征鲳鲹巨噬细胞吞噬微生物的方法 |
| ES2769128T3 (es) | 2017-09-20 | 2020-06-24 | Immunicum Ab | Células dendríticas alogénicas mejoradas para uso en el tratamiento de cáncer |
| CA3087418A1 (en) * | 2018-01-18 | 2019-07-25 | University Of South Florida | Dead antigen stimulated immature heterogenous dendritic cells as therapeutics for diseases |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0689596B1 (en) | 1993-03-16 | 2001-11-07 | Paul Von Hoegen | Stimulation of immune response by viral protein |
| US5788963A (en) * | 1995-07-31 | 1998-08-04 | Pacific Northwest Cancer Foundation | Isolation and/or preservation of dendritic cells for prostate cancer immunotherapy |
| US5985270A (en) * | 1995-09-13 | 1999-11-16 | Fordham University | Adoptive immunotherapy using macrophages sensitized with heat shock protein-epitope complexes |
| CA2278678A1 (en) * | 1997-01-31 | 1998-08-06 | Research Corporation Technologies, Inc. | Cancer immunotherapy with semi-allogeneic cells |
| US6251665B1 (en) * | 1997-02-07 | 2001-06-26 | Cem Cezayirli | Directed maturation of stem cells and production of programmable antigen presenting dentritic cells therefrom |
| EP1064390A4 (en) * | 1998-03-20 | 2002-06-12 | Genzyme Corp | Enhanced anti-tumor immunity |
| US20020025320A1 (en) * | 1999-08-20 | 2002-02-28 | Prosper Boyaka | Sialidases as mucosal adjuvants |
| US20020039583A1 (en) | 1999-09-30 | 2002-04-04 | Subjeck John R. | Stress protein compositions and methods for prevention and treatment of cancer and infectious disease |
| AU2002258941A1 (en) * | 2001-04-20 | 2002-11-05 | Mayo Foundation For Medical Education And Research | Methods of enhancing cell responsiveness |
-
2003
- 2003-06-05 AT AT03730977T patent/ATE517633T1/de not_active IP Right Cessation
- 2003-06-05 US US10/516,915 patent/US20050158328A1/en not_active Abandoned
- 2003-06-05 SI SI200332043T patent/SI1509244T1/sl unknown
- 2003-06-05 AU AU2003241252A patent/AU2003241252A1/en not_active Abandoned
- 2003-06-05 DK DK03730977.0T patent/DK1509244T3/da active
- 2003-06-05 ES ES03730977T patent/ES2369077T3/es not_active Expired - Lifetime
- 2003-06-05 WO PCT/SE2003/000936 patent/WO2003103707A1/en not_active Application Discontinuation
- 2003-06-05 EP EP03730977A patent/EP1509244B1/en not_active Expired - Lifetime
-
2006
- 2006-11-24 US US11/603,819 patent/US8673296B2/en not_active Expired - Lifetime
-
2014
- 2014-01-27 US US14/164,518 patent/US20140141046A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20140141046A1 (en) | 2014-05-22 |
| DK1509244T3 (da) | 2011-10-24 |
| AU2003241252A1 (en) | 2003-12-22 |
| US20050158328A1 (en) | 2005-07-21 |
| US20070134219A1 (en) | 2007-06-14 |
| ATE517633T1 (de) | 2011-08-15 |
| ES2369077T3 (es) | 2011-11-25 |
| EP1509244B1 (en) | 2011-07-27 |
| EP1509244A1 (en) | 2005-03-02 |
| WO2003103707A1 (en) | 2003-12-18 |
| US8673296B2 (en) | 2014-03-18 |
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