SI0854146T1 - Substituted 4-(6-fluoro-(1H)-indol-3-yl)-1,2,3,6-tetrahydropyridine for the treatment of CNS-disorders - Google Patents
Substituted 4-(6-fluoro-(1H)-indol-3-yl)-1,2,3,6-tetrahydropyridine for the treatment of CNS-disordersInfo
- Publication number
- SI0854146T1 SI0854146T1 SI9830009T SI9830009T SI0854146T1 SI 0854146 T1 SI0854146 T1 SI 0854146T1 SI 9830009 T SI9830009 T SI 9830009T SI 9830009 T SI9830009 T SI 9830009T SI 0854146 T1 SI0854146 T1 SI 0854146T1
- Authority
- SI
- Slovenia
- Prior art keywords
- tetrahydropyridine
- indol
- cns
- fluoro
- disorders
- Prior art date
Links
- FBWKDFSEFVFKFY-UHFFFAOYSA-N 6-fluoro-3-(1,2,3,6-tetrahydropyridin-4-yl)-1h-indole Chemical class C=1NC2=CC(F)=CC=C2C=1C1=CCNCC1 FBWKDFSEFVFKFY-UHFFFAOYSA-N 0.000 title 1
- 208000015114 central nervous system disease Diseases 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/06—Peri-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9700895.7A GB9700895D0 (en) | 1997-01-17 | 1997-01-17 | Pharmaceutical compounds |
| EP98300249A EP0854146B1 (en) | 1997-01-17 | 1998-01-14 | Substituted 4-(6-fluoro-[1H]-indol-3-yl)-1,2,3,6-tetrahydropyridine for the treatment of CNS-disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI0854146T1 true SI0854146T1 (en) | 2000-10-31 |
Family
ID=10806121
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI9830009T SI0854146T1 (en) | 1997-01-17 | 1998-01-14 | Substituted 4-(6-fluoro-(1H)-indol-3-yl)-1,2,3,6-tetrahydropyridine for the treatment of CNS-disorders |
Country Status (29)
| Country | Link |
|---|---|
| US (1) | US20010053783A1 (zh) |
| EP (1) | EP0854146B1 (zh) |
| JP (1) | JPH10204090A (zh) |
| KR (1) | KR20000070221A (zh) |
| AR (1) | AR011422A1 (zh) |
| AT (1) | ATE190617T1 (zh) |
| AU (1) | AU5569298A (zh) |
| CA (1) | CA2227132A1 (zh) |
| CZ (1) | CZ290318B6 (zh) |
| DE (1) | DE69800092T2 (zh) |
| DK (1) | DK0854146T3 (zh) |
| EA (1) | EA001469B1 (zh) |
| ES (1) | ES2144888T3 (zh) |
| GB (1) | GB9700895D0 (zh) |
| GR (1) | GR3033316T3 (zh) |
| HU (1) | HUP0000854A3 (zh) |
| ID (1) | ID21920A (zh) |
| IL (1) | IL129647A (zh) |
| NO (1) | NO993372D0 (zh) |
| NZ (1) | NZ335493A (zh) |
| PE (1) | PE99399A1 (zh) |
| PL (1) | PL334569A1 (zh) |
| PT (1) | PT854146E (zh) |
| SI (1) | SI0854146T1 (zh) |
| SV (1) | SV1998000088A (zh) |
| TR (1) | TR199901583T2 (zh) |
| TW (1) | TW396156B (zh) |
| WO (1) | WO1998031686A1 (zh) |
| ZA (1) | ZA98300B (zh) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0897921A1 (en) * | 1997-08-22 | 1999-02-24 | Eli Lilly And Company Limited | Benzothiadiazinyl-indole derivatives and their use as serotonin receptor ligands |
| GB9825413D0 (en) | 1998-11-19 | 1999-01-13 | Lilly Co Eli | Pharmaceutical compounds |
| GB9903784D0 (en) * | 1999-02-18 | 1999-04-14 | Lilly Co Eli | Pharmaceutical compounds |
| AR028945A1 (es) * | 2000-06-19 | 2003-05-28 | Lundbeck & Co As H | Derivados de indol |
| KR101165996B1 (ko) | 2010-04-23 | 2012-07-18 | 주식회사 녹십자 | 프탈라지논 유도체, 이의 제조방법 및 이를 함유하는 약학적 조성물 |
| CN105949190B (zh) * | 2016-07-04 | 2018-06-29 | 烟台凯博医药科技有限公司 | 一种制备1，8-萘啶及衍生物的方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2662696A2 (fr) * | 1989-12-13 | 1991-12-06 | Rhone Poulenc Sante | Antagonistes de la serotonine, leur preparation et medicaments les contenant. |
| DK158590D0 (da) * | 1990-07-02 | 1990-07-02 | Lundbeck & Co As H | Indolderivater |
| FR2675801A1 (fr) * | 1991-04-24 | 1992-10-30 | Rhone Poulenc Rorer Sa | Piperidines, leur preparation et les medicaments les contenant. |
| DE19500689A1 (de) * | 1995-01-12 | 1996-07-18 | Merck Patent Gmbh | Indolpiperidin-Derivate |
| US5576321A (en) * | 1995-01-17 | 1996-11-19 | Eli Lilly And Company | Compounds having effects on serotonin-related systems |
-
1997
- 1997-01-17 GB GBGB9700895.7A patent/GB9700895D0/en active Pending
-
1998
- 1998-01-13 US US09/005,995 patent/US20010053783A1/en not_active Abandoned
- 1998-01-13 TW TW087100373A patent/TW396156B/zh not_active IP Right Cessation
- 1998-01-14 ZA ZA98300A patent/ZA98300B/xx unknown
- 1998-01-14 CZ CZ19991510A patent/CZ290318B6/cs not_active IP Right Cessation
- 1998-01-14 AU AU55692/98A patent/AU5569298A/en not_active Abandoned
- 1998-01-14 TR TR1999/01583T patent/TR199901583T2/xx unknown
- 1998-01-14 SI SI9830009T patent/SI0854146T1/xx unknown
- 1998-01-14 NZ NZ335493A patent/NZ335493A/xx unknown
- 1998-01-14 DK DK98300249T patent/DK0854146T3/da active
- 1998-01-14 EA EA199900667A patent/EA001469B1/ru not_active IP Right Cessation
- 1998-01-14 WO PCT/GB1998/000113 patent/WO1998031686A1/en not_active Application Discontinuation
- 1998-01-14 KR KR1019997006447A patent/KR20000070221A/ko not_active Application Discontinuation
- 1998-01-14 ID IDW990623A patent/ID21920A/id unknown
- 1998-01-14 JP JP10005897A patent/JPH10204090A/ja active Pending
- 1998-01-14 AT AT98300249T patent/ATE190617T1/de not_active IP Right Cessation
- 1998-01-14 PT PT98300249T patent/PT854146E/pt unknown
- 1998-01-14 DE DE69800092T patent/DE69800092T2/de not_active Expired - Fee Related
- 1998-01-14 ES ES98300249T patent/ES2144888T3/es not_active Expired - Lifetime
- 1998-01-14 EP EP98300249A patent/EP0854146B1/en not_active Expired - Lifetime
- 1998-01-14 IL IL12964798A patent/IL129647A/en not_active IP Right Cessation
- 1998-01-14 PL PL98334569A patent/PL334569A1/xx unknown
- 1998-01-14 HU HU0000854A patent/HUP0000854A3/hu unknown
- 1998-01-15 CA CA002227132A patent/CA2227132A1/en not_active Abandoned
- 1998-01-16 AR ARP980100185A patent/AR011422A1/es unknown
- 1998-07-09 PE PE1998000607A patent/PE99399A1/es not_active Application Discontinuation
- 1998-07-16 SV SV1998000088A patent/SV1998000088A/es unknown
-
1999
- 1999-07-08 NO NO993372A patent/NO993372D0/no not_active Application Discontinuation
-
2000
- 2000-04-26 GR GR20000401000T patent/GR3033316T3/el not_active IP Right Cessation
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