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SG159380A1 - Heteroaryl compounds useful as inhibitors of gsk-3 - Google Patents

Heteroaryl compounds useful as inhibitors of gsk-3

Info

Publication number
SG159380A1
SG159380A1 SG200605228-6A SG2006052286A SG159380A1 SG 159380 A1 SG159380 A1 SG 159380A1 SG 2006052286 A SG2006052286 A SG 2006052286A SG 159380 A1 SG159380 A1 SG 159380A1
Authority
SG
Singapore
Prior art keywords
ring
optionally substituted
sulfur
nitrogen
oxygen
Prior art date
Application number
SG200605228-6A
Other languages
English (en)
Inventor
Scott L Harbeson
Michael J Arnost
Jeremy Green
Vladimir Savic
Original Assignee
Vertex Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vertex Pharma filed Critical Vertex Pharma
Publication of SG159380A1 publication Critical patent/SG159380A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4245—Oxadiazoles
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
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    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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SG200605228-6A 2002-02-06 2003-02-06 Heteroaryl compounds useful as inhibitors of gsk-3 SG159380A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US35484302P 2002-02-06 2002-02-06

Publications (1)

Publication Number Publication Date
SG159380A1 true SG159380A1 (en) 2010-03-30

Family

ID=27734431

Family Applications (1)

Application Number Title Priority Date Filing Date
SG200605228-6A SG159380A1 (en) 2002-02-06 2003-02-06 Heteroaryl compounds useful as inhibitors of gsk-3

Country Status (13)

Country Link
US (2) US20040034037A1 (de)
EP (2) EP2322521B1 (de)
JP (2) JP4656838B2 (de)
KR (1) KR20040084896A (de)
AU (1) AU2003215087B2 (de)
CA (1) CA2475633C (de)
ES (1) ES2437391T3 (de)
MX (1) MXPA04007697A (de)
NO (1) NO20043726L (de)
PL (1) PL372198A1 (de)
RU (1) RU2004126671A (de)
SG (1) SG159380A1 (de)
WO (1) WO2003066629A2 (de)

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