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SG11202004260YA - Process for preparing antihelmintic 4-amino-quinoline-3-carboxamide derivatives - Google Patents

Process for preparing antihelmintic 4-amino-quinoline-3-carboxamide derivatives

Info

Publication number
SG11202004260YA
SG11202004260YA SG11202004260YA SG11202004260YA SG11202004260YA SG 11202004260Y A SG11202004260Y A SG 11202004260YA SG 11202004260Y A SG11202004260Y A SG 11202004260YA SG 11202004260Y A SG11202004260Y A SG 11202004260YA SG 11202004260Y A SG11202004260Y A SG 11202004260YA
Authority
SG
Singapore
Prior art keywords
antihelmintic
quinoline
amino
preparing
carboxamide derivatives
Prior art date
Application number
SG11202004260YA
Inventor
Florian Erver
Frank Memmel
Thomas Himmler
Andreas Steib
Marc Nowakowski
Original Assignee
Bayer Animal Health Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Animal Health Gmbh filed Critical Bayer Animal Health Gmbh
Publication of SG11202004260YA publication Critical patent/SG11202004260YA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4709Non-condensed quinolines and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/10Anthelmintics
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J23/00Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00
    • B01J23/38Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of noble metals
    • B01J23/40Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of noble metals of the platinum group metals
    • B01J23/44Palladium
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
SG11202004260YA 2017-12-15 2018-12-14 Process for preparing antihelmintic 4-amino-quinoline-3-carboxamide derivatives SG11202004260YA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP17207586 2017-12-15
PCT/EP2018/084964 WO2019115768A1 (en) 2017-12-15 2018-12-14 Process for preparing antihelmintic 4-amino-quinoline-3-carboxamide derivatives

Publications (1)

Publication Number Publication Date
SG11202004260YA true SG11202004260YA (en) 2020-06-29

Family

ID=60673654

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202004260YA SG11202004260YA (en) 2017-12-15 2018-12-14 Process for preparing antihelmintic 4-amino-quinoline-3-carboxamide derivatives

Country Status (17)

Country Link
US (1) US11505544B2 (en)
EP (1) EP3692037A1 (en)
JP (1) JP7516245B2 (en)
KR (1) KR20200099548A (en)
CN (1) CN111448192B (en)
AU (1) AU2018382999B2 (en)
CA (1) CA3085675A1 (en)
CL (1) CL2020001589A1 (en)
CO (1) CO2020007222A2 (en)
DO (1) DOP2020000118A (en)
IL (1) IL275216A (en)
MX (1) MX2020006185A (en)
PH (1) PH12020550905A1 (en)
SG (1) SG11202004260YA (en)
TW (1) TWI809018B (en)
UY (1) UY38009A (en)
WO (1) WO2019115768A1 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102785432B1 (en) 2018-07-09 2025-03-21 베링거잉겔하임베트메디카게엠베하 Antiparasitic heterocyclic compounds
CA3122106C (en) * 2018-12-18 2024-05-28 Elanco Tiergesundheit Ag Bicyclic derivatives
AR118435A1 (en) 2019-03-19 2021-10-06 Boehringer Ingelheim Animal Health Usa Inc AZA-BENZOTHIOPHENE AND AZA-BENZOFURAN COMPOUNDS AS ANTIHELMINTICS
CA3179528A1 (en) * 2020-04-09 2021-10-14 Bayer Animal Health Gmbh Substituted condensed azines as anthelmintic compounds
CN116249704A (en) 2020-05-29 2023-06-09 勃林格殷格翰动物保健美国公司 Heterocyclic compounds for insect repellent
EP4148052A1 (en) * 2021-09-09 2023-03-15 Bayer Animal Health GmbH New quinoline derivatives
WO2023073641A1 (en) 2021-11-01 2023-05-04 Boehringer Ingelheim Vetmedica Gmbh Anthelmintic pyrrolopyridazine compounds
KR20240154881A (en) 2023-04-19 2024-10-28 오신희 Support hanger for various facilities with earthquake-proof and damping structure
WO2025027117A1 (en) 2023-08-02 2025-02-06 Intervet International B.V. Carboxamide-4-quinoline compounds with anthelmintic activity

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1128790C (en) * 1997-12-22 2003-11-26 法玛西雅厄普约翰美国公司 4-hydroxyquinoline-3-carboxamides and hydrazides as antiviral agents
MXPA02006474A (en) 1999-12-28 2002-11-29 Eisai Co Ltd Heterocyclic compounds having sulfonamide groups.
CN100356979C (en) 2000-02-03 2007-12-26 卫材R&D管理有限公司 Integrin expression inhibitors
JP2008214323A (en) 2007-03-08 2008-09-18 Kyowa Hakko Kogyo Co Ltd Treating and/or prophylactic agent of skin disease
AR089939A1 (en) 2012-02-09 2014-10-01 Glenmark Pharmaceuticals Sa BICYCLE COMPOUNDS AS INHIBITORS OF mPGES-1
AR098475A1 (en) * 2013-11-26 2016-06-01 Bayer Cropscience Ag PESTICIDE COMPOUNDS AND USES
AU2015237050B2 (en) 2014-03-24 2019-05-09 Guangdong Zhongsheng Pharmaceutical Co., Ltd Quinoline derivatives as SMO inhibitors
UY37028A (en) 2015-12-17 2017-07-31 Astex Therapeutics Ltd INHIBITING COMPOUNDS OF PROSTAGLANDINA D SINTASA EMATOPOYÉTICA (H-PGDS
EP3538512B1 (en) * 2016-11-11 2021-06-16 Bayer Animal Health GmbH New anthelmintic quinoline-3-carboxamide derivatives

Also Published As

Publication number Publication date
TWI809018B (en) 2023-07-21
IL275216A (en) 2020-07-30
UY38009A (en) 2019-07-31
CA3085675A1 (en) 2019-06-20
JP7516245B2 (en) 2024-07-16
RU2020123282A (en) 2022-01-17
PH12020550905A1 (en) 2021-05-17
AU2018382999A1 (en) 2020-05-28
MX2020006185A (en) 2020-09-03
US11505544B2 (en) 2022-11-22
CO2020007222A2 (en) 2020-11-20
EP3692037A1 (en) 2020-08-12
DOP2020000118A (en) 2020-08-31
BR112020011901A2 (en) 2020-11-24
KR20200099548A (en) 2020-08-24
CL2020001589A1 (en) 2020-11-20
CN111448192B (en) 2024-04-12
AU2018382999B2 (en) 2023-11-23
WO2019115768A1 (en) 2019-06-20
JP2021506774A (en) 2021-02-22
CN111448192A (en) 2020-07-24
US20200308153A1 (en) 2020-10-01
TW201927773A (en) 2019-07-16

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