SG11202000773QA - Liposomal formulation for joint lubrication - Google Patents

Liposomal formulation for joint lubrication

Info

Publication number: SG11202000773QA
Authority: SG; Singapore
Prior art keywords: liposomal formulation; joint lubrication; lubrication; joint; liposomal
Prior art date: 2017-08-22

Application number

SG11202000773QA

Other languages

English (en)

Inventor

Yechezkel Barenholz

Yaniv Dolev

Keren Turjeman

Gadi Sarfati

Maty Ayal-Hershkovitz

Original Assignee

Moebius Medical Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2017-08-22

Filing date

2018-08-21

Publication date

2020-03-30

2018-08-21 Application filed by Moebius Medical Ltd filed Critical Moebius Medical Ltd

2020-03-30 Publication of SG11202000773QA publication Critical patent/SG11202000773QA/en

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/047—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
- A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/54—Biologically active materials, e.g. therapeutic substances
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/22—Lipids, fatty acids, e.g. prostaglandins, oils, fats, waxes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/06—Flowable or injectable implant compositions
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/10—Materials for lubricating medical devices
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/06—Materials or treatment for tissue regeneration for cartilage reconstruction, e.g. meniscus
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/24—Materials or treatment for tissue regeneration for joint reconstruction

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Epidemiology (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Oil, Petroleum & Natural Gas (AREA)
Dermatology (AREA)
Molecular Biology (AREA)
Oral & Maxillofacial Surgery (AREA)
Transplantation (AREA)
Dispersion Chemistry (AREA)
Biochemistry (AREA)
Immunology (AREA)
Orthopedic Medicine & Surgery (AREA)
Rheumatology (AREA)
Bioinformatics & Cheminformatics (AREA)
Physical Education & Sports Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Biomedical Technology (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

SG11202000773QA 2017-08-22 2018-08-21 Liposomal formulation for joint lubrication SG11202000773QA (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US201762548429P	2017-08-22	2017-08-22
PCT/IL2018/050923 WO2019038763A1 (fr)	2017-08-22	2018-08-21	Formulation liposomale pour lubrification d'articulation

Publications (1)

Publication Number	Publication Date
SG11202000773QA true SG11202000773QA (en)	2020-03-30

Family

ID=65439381

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SG11202000773QA SG11202000773QA (en)	2017-08-22	2018-08-21	Liposomal formulation for joint lubrication

Country Status (25)

Country	Link
US (3)	US11123293B2 (fr)
EP (2)	EP3672653B1 (fr)
JP (2)	JP7082336B2 (fr)
KR (2)	KR102808544B1 (fr)
CN (2)	CN111065423B (fr)
AU (3)	AU2018319594B2 (fr)
BR (1)	BR112020003767B1 (fr)
CA (2)	CA3219776A1 (fr)
DK (1)	DK3672653T3 (fr)
EA (1)	EA202090476A1 (fr)
ES (1)	ES2948715T3 (fr)
FI (1)	FI3672653T3 (fr)
HR (1)	HRP20230566T1 (fr)
HU (1)	HUE062030T2 (fr)
IL (3)	IL272630B2 (fr)
LT (1)	LT3672653T (fr)
MA (1)	MA49959B1 (fr)
MX (2)	MX2020002041A (fr)
MY (1)	MY197149A (fr)
PH (1)	PH12020500331A1 (fr)
PL (1)	PL3672653T3 (fr)
PT (1)	PT3672653T (fr)
SG (1)	SG11202000773QA (fr)
SI (1)	SI3672653T1 (fr)
WO (1)	WO2019038763A1 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
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TWI782181B (zh) *	2019-02-11	2022-11-01	以色列商莫比斯醫療有限公司	用於關節潤滑的脂質體調配物
JP2021013788A (ja) *	2020-11-10	2021-02-12	株式会社三洋物産	遊技機
WO2024154134A1 (fr)	2023-01-19	2024-07-25	Moebius Medical Ltd.	Composition liposomale à action prolongée pour le traitement de la douleur dans des troubles articulaires
KR20250018222A (ko) *	2023-07-26	2025-02-05	차의과학대학교 산학협력단	미토콘드리아가 캡슐화된 세포막 융합유도 리포좀을 포함하는 골관절염 치료를 위한 약학 조성물

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US5941909A (en) *	1995-02-14	1999-08-24	Mentor Corporation	Filling material for soft tissue implant prostheses and implants made therewith
AUPN723395A0 (en)	1995-12-19	1996-01-18	Macnaught Medical Pty Limited	Lubrication methods
US6379648B1 (en) *	1999-02-01	2002-04-30	The Curators Of The University Of Missouri	Biodegradable glass compositions and methods for radiation therapy
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EP1353659A1 (fr) *	2001-01-24	2003-10-22	Mestex AG	Utilisation de substances neurotoxiques pour la production d'un agent servant a traiter les douleurs articulaires
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CA2451245A1 (fr) *	2001-06-25	2003-01-03	Depuy International Limited	Encapsulation liposomale de glycosaminoglycanes pour le traitement d'articulations arthrosees
CA2451248A1 (fr)	2001-06-25	2003-01-03	Depuy International Limited	Composition comprenant des glycosaminoglycanes et des inhibiteurs d'hyaluronidase destinee au traitement d'articulations arthritiques
US20060029655A1 (en)	2001-06-25	2006-02-09	Yissum Research Development Company Of The Hebrew University Of Jerusalem	Method for preparation of vesicles loaded with biological material and different uses thereof
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BR112012032153A2 (pt)	2010-06-17	2017-08-08	Yeda Res And Development Company Ltd	método para a lubrificação de uma ou mais superfícies não biológicas, método para a lubrificação de uma ou mais superfícies de um tecido biológico em um indivíduo mamífero, uso de lipossomas na fase em gel e lipossoma misto
IL206739A (en)	2010-06-30	2016-06-30	David Segal	An injectable drug containing silitol as an active substance
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CN104688721A (zh)	2014-10-11	2015-06-10	黄萍	一种含紫杉醇脂质体的抗类风湿性关节炎药物凝胶剂及其制备方法

2018
- 2018-08-21 SI SI201830942T patent/SI3672653T1/sl unknown
- 2018-08-21 PL PL18847493.6T patent/PL3672653T3/pl unknown
- 2018-08-21 HR HRP20230566TT patent/HRP20230566T1/hr unknown
- 2018-08-21 BR BR112020003767-2A patent/BR112020003767B1/pt active IP Right Grant
- 2018-08-21 LT LTEPPCT/IL2018/050923T patent/LT3672653T/lt unknown
- 2018-08-21 ES ES18847493T patent/ES2948715T3/es active Active
- 2018-08-21 DK DK18847493.6T patent/DK3672653T3/da active
- 2018-08-21 EP EP18847493.6A patent/EP3672653B1/fr active Active
- 2018-08-21 MY MYPI2020000726A patent/MY197149A/en unknown
- 2018-08-21 AU AU2018319594A patent/AU2018319594B2/en active Active
- 2018-08-21 IL IL272630A patent/IL272630B2/en unknown
- 2018-08-21 HU HUE18847493A patent/HUE062030T2/hu unknown
- 2018-08-21 MX MX2020002041A patent/MX2020002041A/es unknown
- 2018-08-21 JP JP2020511447A patent/JP7082336B2/ja active Active
- 2018-08-21 PT PT188474936T patent/PT3672653T/pt unknown
- 2018-08-21 EP EP23160029.7A patent/EP4223284A1/fr active Pending
- 2018-08-21 IL IL312816A patent/IL312816A/en unknown
- 2018-08-21 CN CN201880053772.8A patent/CN111065423B/zh active Active
- 2018-08-21 KR KR1020237040609A patent/KR102808544B1/ko active Active
- 2018-08-21 FI FIEP18847493.6T patent/FI3672653T3/fi active
- 2018-08-21 KR KR1020207006061A patent/KR102607729B1/ko active Active
- 2018-08-21 US US16/337,188 patent/US11123293B2/en active Active
- 2018-08-21 MA MA49959A patent/MA49959B1/fr unknown
- 2018-08-21 WO PCT/IL2018/050923 patent/WO2019038763A1/fr active Application Filing
- 2018-08-21 CA CA3219776A patent/CA3219776A1/fr active Pending
- 2018-08-21 CA CA3073368A patent/CA3073368C/fr active Active
- 2018-08-21 CN CN202210282704.7A patent/CN114601799B/zh active Active
- 2018-08-21 SG SG11202000773QA patent/SG11202000773QA/en unknown
- 2018-08-21 EA EA202090476A patent/EA202090476A1/ru unknown
- 2018-08-21 IL IL301801A patent/IL301801B2/en unknown
2020
- 2020-02-13 PH PH12020500331A patent/PH12020500331A1/en unknown
- 2020-02-21 MX MX2023009082A patent/MX2023009082A/es unknown
2021
- 2021-08-15 US US17/445,089 patent/US12214077B2/en active Active
2022
- 2022-05-17 JP JP2022080859A patent/JP7383759B2/ja active Active
2023
- 2023-05-26 AU AU2023203309A patent/AU2023203309B2/en active Active
2024
- 2024-12-17 US US18/984,974 patent/US20250114304A1/en active Pending
2025
- 2025-01-07 AU AU2025200077A patent/AU2025200077A1/en active Pending

Also Published As

Publication number	Publication date
BR112020003767B1 (pt)	2023-10-10
JP7082336B2 (ja)	2022-06-08
CN114601799B (zh)	2023-09-26
IL312816A (en)	2024-07-01
PH12020500331A1 (en)	2020-10-05
CA3219776A1 (fr)	2019-02-28
US20250114304A1 (en)	2025-04-10
AU2023203309A1 (en)	2023-06-22
IL301801B1 (en)	2024-06-01
DK3672653T3 (da)	2023-06-12
IL301801A (en)	2023-05-01
ES2948715T3 (es)	2023-09-18
IL272630B1 (en)	2023-05-01
US11123293B2 (en)	2021-09-21
HRP20230566T1 (hr)	2023-08-18
PL3672653T3 (pl)	2023-08-14
JP7383759B2 (ja)	2023-11-20
JP2020531538A (ja)	2020-11-05
EP4223284A1 (fr)	2023-08-09
NZ761298A (en)	2024-03-22
MA49959A (fr)	2020-07-01
MX2020002041A (es)	2020-08-13
US20200170948A1 (en)	2020-06-04
KR20200044006A (ko)	2020-04-28
KR102607729B1 (ko)	2023-11-29
CA3073368C (fr)	2024-01-02
IL272630B2 (en)	2023-09-01
AU2018319594A1 (en)	2020-02-20
MY197149A (en)	2023-05-26
JP2022110090A (ja)	2022-07-28
FI3672653T3 (fi)	2023-06-07
AU2023203309B2 (en)	2024-10-10
PT3672653T (pt)	2023-06-29
SI3672653T1 (sl)	2023-08-31
HUE062030T2 (hu)	2023-09-28
MX2023009082A (es)	2023-08-08
EP3672653B1 (fr)	2023-03-29
CN111065423B (zh)	2022-04-12
IL272630A (en)	2020-03-31
KR102808544B1 (ko)	2025-05-19
MA49959B1 (fr)	2023-07-31
CN114601799A (zh)	2022-06-10
KR20230166148A (ko)	2023-12-06
BR112020003767A2 (pt)	2020-09-01
CN111065423A (zh)	2020-04-24
LT3672653T (lt)	2023-07-10
EA202090476A1 (ru)	2020-06-29
CA3073368A1 (fr)	2019-02-28
WO2019038763A1 (fr)	2019-02-28
US20210369613A1 (en)	2021-12-02
IL301801B2 (en)	2024-10-01
US12214077B2 (en)	2025-02-04
EP3672653A1 (fr)	2020-07-01
AU2025200077A1 (en)	2025-01-23
AU2018319594B2 (en)	2023-06-15
EP3672653A4 (fr)	2021-01-13

Publication	Publication Date	Title
ZA201607310B (en)	2020-08-26	Lubricant formulations
IL274139A (en)	2020-06-30	Sprayable formulation
IL272630B1 (en)	2023-05-01	Liposomal formulations for joint lubrication
IL282617A (en)	2021-06-30	Aerosol formulation
GB201801614D0 (en)	2018-03-14	Formulation
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