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SG11201710695XA - 1,4-disubstituted imidazole derivative - Google Patents

1,4-disubstituted imidazole derivative

Info

Publication number
SG11201710695XA
SG11201710695XA SG11201710695XA SG11201710695XA SG11201710695XA SG 11201710695X A SG11201710695X A SG 11201710695XA SG 11201710695X A SG11201710695X A SG 11201710695XA SG 11201710695X A SG11201710695X A SG 11201710695XA SG 11201710695X A SG11201710695X A SG 11201710695XA
Authority
SG
Singapore
Prior art keywords
imidazole derivative
disubstituted imidazole
disubstituted
derivative
imidazole
Prior art date
Application number
SG11201710695XA
Other languages
English (en)
Inventor
Hitoshi Ban
Manabu Kusagi
Shingo Tojo
Futoshi Hasegawa
Miki Hashizume
Original Assignee
Sumitomo Dainippon Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Dainippon Pharma Co Ltd filed Critical Sumitomo Dainippon Pharma Co Ltd
Publication of SG11201710695XA publication Critical patent/SG11201710695XA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00Carboxylic acid amides
    • C07C233/88Carboxylic acid amides having nitrogen atoms of carboxamide groups bound to an acyclic carbon atom and to a carbon atom of a six-membered aromatic ring wherein at least one ortho-hydrogen atom has been replaced
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42Oxazoles
    • A61K31/422Oxazoles not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4709Non-condensed quinolines and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
SG11201710695XA 2015-06-22 2016-06-21 1,4-disubstituted imidazole derivative SG11201710695XA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2015125174 2015-06-22
JP2015244856 2015-12-16
PCT/JP2016/068423 WO2016208591A1 (ja) 2015-06-22 2016-06-21 1,4-ジ置換イミダゾール誘導体

Publications (1)

Publication Number Publication Date
SG11201710695XA true SG11201710695XA (en) 2018-01-30

Family

ID=57584875

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201710695XA SG11201710695XA (en) 2015-06-22 2016-06-21 1,4-disubstituted imidazole derivative

Country Status (13)

Country Link
US (3) US10807945B2 (ko)
EP (1) EP3312170A4 (ko)
JP (1) JP6692354B2 (ko)
KR (1) KR20180028456A (ko)
CN (1) CN107922386B (ko)
AU (1) AU2016284398C1 (ko)
CA (1) CA2990583A1 (ko)
HK (1) HK1248226A1 (ko)
PH (1) PH12017502388A1 (ko)
RU (1) RU2741000C2 (ko)
SG (1) SG11201710695XA (ko)
TW (1) TW201713642A (ko)
WO (1) WO2016208591A1 (ko)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107922348A (zh) 2015-06-22 2018-04-17 大日本住友制药株式会社 双环杂环酰胺衍生物
SG11201710695XA (en) * 2015-06-22 2018-01-30 Sumitomo Dainippon Pharma Co Ltd 1,4-disubstituted imidazole derivative
US10898469B2 (en) 2016-02-26 2021-01-26 Sumitomo Dainippon Pharma Co., Ltd. Imidazolylamide derivative
JP7123809B2 (ja) * 2016-12-20 2022-08-23 住友ファーマ株式会社 未分化iPS細胞の除去剤
JPWO2018117196A1 (ja) * 2016-12-20 2019-10-31 大日本住友製薬株式会社 がん幹細胞を標的とする医薬
JP6775483B2 (ja) * 2016-12-20 2020-10-28 大日本住友製薬株式会社 1,4−ジ置換イミダゾール誘導体からなる医薬
FI3770162T3 (fi) 2018-03-20 2023-06-02 Sumitomo Pharma Co Ltd Dihydrokromeenijohdannainen
US10829485B2 (en) * 2018-04-06 2020-11-10 Black Belt Tx Ltd ATF6 inhibitors and uses thereof
JP7287929B2 (ja) * 2019-09-25 2023-06-06 住友ファーマ株式会社 ジヒドロクロメン誘導体を含有する医薬

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5359664A (en) * 1976-11-10 1978-05-29 Sumitomo Chem Co Ltd Novel imidazole derivatives
US4140788A (en) * 1976-11-10 1979-02-20 Sumitomo Chemical Company, Limited N-Substituted imidazolecarboxamide derivatives
EP0858457A1 (de) * 1995-10-20 1998-08-19 Dr. Karl Thomae GmbH 5-gliedrige heterocyclen, diese verbindungen enthaltende arzneimittel und deren verwendung sowie verfahren zu ihrer herstellung
US6310070B1 (en) 1997-07-15 2001-10-30 Japan Energy Corporation Purine derivatives and medicinal use thereof
DK1730119T3 (da) * 2004-03-23 2008-08-11 Pfizer Prod Inc Imidazolforbindelser til behandling af neurodegenerative forstyrrelser
SE0401653D0 (sv) 2004-06-24 2004-06-24 Astrazeneca Ab New compounds
JP2008530179A (ja) 2005-02-16 2008-08-07 ソルベイ・フアーマシユーチカルズ・ベー・ブイ カンナビノイドcb2受容体モジュレーターとしての1h−イミダゾール誘導体
AR052666A1 (es) * 2005-02-16 2007-03-28 Solvay Pharm Bv Derivados de 1h-imidazol como moduladores del receptor cannabinoide cb2
DE102005008183A1 (de) 2005-02-23 2006-08-31 Bayer Healthcare Ag Heterocyclylamid-substituierte Imidazole
GB0508472D0 (en) 2005-04-26 2005-06-01 Glaxo Group Ltd Compounds
EP1968946A4 (en) 2005-12-23 2010-05-05 Astrazeneca Ab IMIDAZOLE AS MODULATORS OF THE GABA B RECEPTOR
WO2008073461A2 (en) 2006-12-11 2008-06-19 Wyeth Ion channel modulators
GB0722075D0 (en) * 2007-11-09 2007-12-19 Smithkline Beecham Corp Compounds
SI2688885T1 (sl) 2011-03-22 2016-10-28 Bayer Intellectual Property Gmbh N-(1,3,4-oksadiazol-2-il)arilkarboksamidi in njihova uporaba kot herbicidi
PH12014500820A1 (en) * 2011-10-18 2014-05-19 Astellas Pharma Inc Bicyclic heterocyclic compound
WO2015151490A1 (ja) * 2014-03-31 2015-10-08 大日本住友製薬株式会社 新規な三環性キノン誘導体
GB201416754D0 (en) * 2014-09-23 2014-11-05 Mission Therapeutics Ltd Novel compounds
SG11201710695XA (en) 2015-06-22 2018-01-30 Sumitomo Dainippon Pharma Co Ltd 1,4-disubstituted imidazole derivative

Also Published As

Publication number Publication date
JPWO2016208591A1 (ja) 2018-04-05
CN107922386B (zh) 2021-04-02
US20180230085A1 (en) 2018-08-16
US9828362B2 (en) 2017-11-28
US20210171440A1 (en) 2021-06-10
PH12017502388A1 (en) 2018-07-09
EP3312170A1 (en) 2018-04-25
TW201713642A (zh) 2017-04-16
AU2016284398B2 (en) 2020-08-06
RU2741000C2 (ru) 2021-01-22
US10807945B2 (en) 2020-10-20
AU2016284398A1 (en) 2018-02-01
HK1248226A1 (en) 2018-10-12
KR20180028456A (ko) 2018-03-16
RU2018102087A (ru) 2019-07-23
WO2016208591A1 (ja) 2016-12-29
RU2018102087A3 (ko) 2019-12-25
AU2016284398C1 (en) 2021-01-07
US20170166552A1 (en) 2017-06-15
CN107922386A (zh) 2018-04-17
JP6692354B2 (ja) 2020-05-13
CA2990583A1 (en) 2016-12-29
US11661397B2 (en) 2023-05-30
EP3312170A4 (en) 2018-12-12

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