SG11201601471SA - Diagnostic methods and compositions for treatment of glioblastoma - Google Patents
Diagnostic methods and compositions for treatment of glioblastomaInfo
- Publication number
- SG11201601471SA SG11201601471SA SG11201601471SA SG11201601471SA SG11201601471SA SG 11201601471S A SG11201601471S A SG 11201601471SA SG 11201601471S A SG11201601471S A SG 11201601471SA SG 11201601471S A SG11201601471S A SG 11201601471SA SG 11201601471S A SG11201601471S A SG 11201601471SA
- Authority
- SG
- Singapore
- Prior art keywords
- glioblastoma
- compositions
- treatment
- diagnostic methods
- diagnostic
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- G01N33/57557—
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Oncology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Epidemiology (AREA)
- Analytical Chemistry (AREA)
- Pathology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Mycology (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Hospice & Palliative Care (AREA)
- General Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Urology & Nephrology (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361872346P | 2013-08-30 | 2013-08-30 | |
| PCT/US2014/053500 WO2015031808A2 (en) | 2013-08-30 | 2014-08-29 | Diagnostic methods and compositions for treatment of glioblastoma |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201601471SA true SG11201601471SA (en) | 2016-03-30 |
Family
ID=52583566
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201601471SA SG11201601471SA (en) | 2013-08-30 | 2014-08-29 | Diagnostic methods and compositions for treatment of glioblastoma |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US10456470B2 (en) |
| EP (1) | EP3038646B1 (en) |
| JP (2) | JP6664323B2 (en) |
| KR (1) | KR20160048196A (en) |
| CN (1) | CN105611940A (en) |
| AR (1) | AR097500A1 (en) |
| AU (1) | AU2014312079B2 (en) |
| BR (1) | BR112016004305A2 (en) |
| CA (1) | CA2921515A1 (en) |
| HK (1) | HK1221422A1 (en) |
| IL (1) | IL244089A0 (en) |
| MX (1) | MX2016002423A (en) |
| RU (1) | RU2706968C2 (en) |
| SG (1) | SG11201601471SA (en) |
| WO (1) | WO2015031808A2 (en) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10617755B2 (en) | 2013-08-30 | 2020-04-14 | Genentech, Inc. | Combination therapy for the treatment of glioblastoma |
| US9840553B2 (en) | 2014-06-28 | 2017-12-12 | Kodiak Sciences Inc. | Dual PDGF/VEGF antagonists |
| WO2016011052A1 (en) | 2014-07-14 | 2016-01-21 | Genentech, Inc. | Diagnostic methods and compositions for treatment of glioblastoma |
| WO2017025962A1 (en) * | 2015-08-10 | 2017-02-16 | Tel Hashomer Medical Research, Infrastructure And Services Ltd | Prediction of response to immunotherapy based on tumor biomarkers |
| CA2940470C (en) * | 2015-09-18 | 2019-08-20 | Signpath Pharma Inc. | Treatment for glioblastoma |
| WO2017079695A1 (en) * | 2015-11-05 | 2017-05-11 | Tocagen Inc. | Gene expression patterns to predict responsiveness to virotherapy in cancer indications |
| EP3397276A4 (en) | 2015-12-30 | 2019-12-18 | Kodiak Sciences Inc. | ANTIBODIES AND CONJUGATES THEREOF |
| CN106874647B (en) * | 2017-01-06 | 2019-03-22 | 吴安华 | A system for predicting the survival of patients with glioblastoma |
| CN111684078B (en) * | 2018-02-12 | 2024-04-19 | 豪夫迈·罗氏有限公司 | Methods for predicting response to treatment by assessing tumor genetic heterogeneity |
| KR20200140817A (en) | 2018-03-02 | 2020-12-16 | 코디악 사이언시스 인코포레이티드 | IL-6 antibodies and fusion constructs and conjugates thereof |
| EP3915121A1 (en) * | 2019-01-23 | 2021-12-01 | The Regents Of The University Of Michigan | Methods and system for the reconstruction of drug response and disease networks and uses thereof |
| CN109762903B (en) * | 2019-01-31 | 2022-02-01 | 山东大学齐鲁医院 | Application of miR-1246 and/or TERF2IP in diagnosis and treatment of glioma |
| KR102256859B1 (en) * | 2019-03-12 | 2021-05-27 | 건국대학교 산학협력단 | Composition for diagnosing Alzheimer's disease |
| KR102078500B1 (en) * | 2019-03-12 | 2020-02-17 | 건국대학교 산학협력단 | Composition for diagnosing Alzheimer's disease |
| EP3969907B1 (en) * | 2019-05-13 | 2025-09-24 | F. Hoffmann-La Roche AG | Interference-suppressed pharmacokinetic immunoassay |
| CN110412277B (en) * | 2019-06-26 | 2022-09-09 | 四川大学华西医院 | Application of SNAP91 autoantibody detection reagent in preparation of lung cancer screening kit |
| WO2021034091A1 (en) * | 2019-08-19 | 2021-02-25 | 재단법인 아산사회복지재단 | Method for diagnosing glioblastoma |
| CN114786731A (en) | 2019-10-10 | 2022-07-22 | 科达制药股份有限公司 | Methods of treating ocular disorders |
| CN111996251B (en) * | 2020-06-19 | 2024-03-26 | 皖南医学院第一附属医院(皖南医学院弋矶山医院) | Application of malignant glioma biomarker |
| CN114075604B (en) * | 2022-01-18 | 2022-04-08 | 天津医科大学总医院 | Glioblastoma prognosis prediction scoring model and its application in guiding clinical precision diagnosis and treatment |
Family Cites Families (80)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3773919A (en) | 1969-10-23 | 1973-11-20 | Du Pont | Polylactide-drug mixtures |
| US4018653A (en) | 1971-10-29 | 1977-04-19 | U.S. Packaging Corporation | Instrument for the detection of Neisseria gonorrhoeae without culture |
| US4016043A (en) | 1975-09-04 | 1977-04-05 | Akzona Incorporated | Enzymatic immunological method for the determination of antigens and antibodies |
| US4424279A (en) | 1982-08-12 | 1984-01-03 | Quidel | Rapid plunger immunoassay method and apparatus |
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US6548640B1 (en) | 1986-03-27 | 2003-04-15 | Btg International Limited | Altered antibodies |
| IL85035A0 (en) | 1987-01-08 | 1988-06-30 | Int Genetic Eng | Polynucleotide molecule,a chimeric antibody with specificity for human b cell surface antigen,a process for the preparation and methods utilizing the same |
| US5283187A (en) | 1987-11-17 | 1994-02-01 | Brown University Research Foundation | Cell culture-containing tubular capsule produced by co-extrusion |
| US4892538A (en) | 1987-11-17 | 1990-01-09 | Brown University Research Foundation | In vivo delivery of neurotransmitters by implanted, encapsulated cells |
| WO1989006692A1 (en) | 1988-01-12 | 1989-07-27 | Genentech, Inc. | Method of treating tumor cells by inhibiting growth factor receptor function |
| US5700637A (en) | 1988-05-03 | 1997-12-23 | Isis Innovation Limited | Apparatus and method for analyzing polynucleotide sequences and method of generating oligonucleotide arrays |
| GB8823869D0 (en) | 1988-10-12 | 1988-11-16 | Medical Res Council | Production of antibodies |
| US5143854A (en) | 1989-06-07 | 1992-09-01 | Affymax Technologies N.V. | Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof |
| DE3920358A1 (en) | 1989-06-22 | 1991-01-17 | Behringwerke Ag | BISPECIFIC AND OLIGO-SPECIFIC, MONO- AND OLIGOVALENT ANTI-BODY CONSTRUCTS, THEIR PRODUCTION AND USE |
| US6075181A (en) | 1990-01-12 | 2000-06-13 | Abgenix, Inc. | Human antibodies derived from immunized xenomice |
| US6150584A (en) | 1990-01-12 | 2000-11-21 | Abgenix, Inc. | Human antibodies derived from immunized xenomice |
| DK0463151T3 (en) | 1990-01-12 | 1996-07-01 | Cell Genesys Inc | Generation of xenogenic antibodies |
| US5545806A (en) | 1990-08-29 | 1996-08-13 | Genpharm International, Inc. | Ransgenic non-human animals for producing heterologous antibodies |
| US5633425A (en) | 1990-08-29 | 1997-05-27 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| US5661016A (en) | 1990-08-29 | 1997-08-26 | Genpharm International Inc. | Transgenic non-human animals capable of producing heterologous antibodies of various isotypes |
| JP2938569B2 (en) | 1990-08-29 | 1999-08-23 | ジェンファーム インターナショナル,インコーポレイティド | Method for producing xenogeneic immunoglobulin and transgenic mouse |
| US5770429A (en) | 1990-08-29 | 1998-06-23 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| US5625126A (en) | 1990-08-29 | 1997-04-29 | Genpharm International, Inc. | Transgenic non-human animals for producing heterologous antibodies |
| DE69129154T2 (en) | 1990-12-03 | 1998-08-20 | Genentech, Inc., South San Francisco, Calif. | METHOD FOR ENRICHING PROTEIN VARIANTS WITH CHANGED BINDING PROPERTIES |
| US6582959B2 (en) | 1991-03-29 | 2003-06-24 | Genentech, Inc. | Antibodies to vascular endothelial cell growth factor |
| US20030206899A1 (en) | 1991-03-29 | 2003-11-06 | Genentech, Inc. | Vascular endothelial cell growth factor antagonists |
| JP4124480B2 (en) | 1991-06-14 | 2008-07-23 | ジェネンテック・インコーポレーテッド | Immunoglobulin variants |
| WO1994004679A1 (en) | 1991-06-14 | 1994-03-03 | Genentech, Inc. | Method for making humanized antibodies |
| GB9114948D0 (en) | 1991-07-11 | 1991-08-28 | Pfizer Ltd | Process for preparing sertraline intermediates |
| WO1993025673A1 (en) | 1992-06-04 | 1993-12-23 | The Regents Of The University Of California | In vivo gene therapy with intron-free sequence of interest |
| DE69233803D1 (en) | 1992-10-28 | 2011-03-31 | Genentech Inc | Use of vascular endothelial growth factor antagonists |
| US5635388A (en) | 1994-04-04 | 1997-06-03 | Genentech, Inc. | Agonist antibodies against the flk2/flt3 receptor and uses thereof |
| US5807522A (en) | 1994-06-17 | 1998-09-15 | The Board Of Trustees Of The Leland Stanford Junior University | Methods for fabricating microarrays of biological samples |
| US5910486A (en) | 1994-09-06 | 1999-06-08 | Uab Research Foundation | Methods for modulating protein function in cells using, intracellular antibody homologues |
| IL117645A (en) | 1995-03-30 | 2005-08-31 | Genentech Inc | Vascular endothelial cell growth factor antagonists for use as medicaments in the treatment of age-related macular degeneration |
| DE69637481T2 (en) | 1995-04-27 | 2009-04-09 | Amgen Fremont Inc. | Human antibodies to IL-8 derived from immunized Xenomae |
| AU2466895A (en) | 1995-04-28 | 1996-11-18 | Abgenix, Inc. | Human antibodies derived from immunized xenomice |
| US6267958B1 (en) | 1995-07-27 | 2001-07-31 | Genentech, Inc. | Protein formulation |
| CA2273194C (en) | 1996-12-03 | 2011-02-01 | Abgenix, Inc. | Transgenic mammals having human ig loci including plural vh and vk regions and antibodies produced therefrom |
| US20020032315A1 (en) | 1997-08-06 | 2002-03-14 | Manuel Baca | Anti-vegf antibodies |
| US6884879B1 (en) | 1997-04-07 | 2005-04-26 | Genentech, Inc. | Anti-VEGF antibodies |
| ATE501170T1 (en) | 1997-04-07 | 2011-03-15 | Genentech Inc | METHOD FOR PRODUCING HUMANIZED ANTIBODIES BY RANDOMIZED MUtagenesis |
| NZ500078A (en) | 1997-04-07 | 2001-10-26 | Genentech Inc | Humanized anti-VEGF antibodies and their use in inhibiting VEGF-induced angiogenesis in mammals |
| US6610833B1 (en) | 1997-11-24 | 2003-08-26 | The Institute For Human Genetics And Biochemistry | Monoclonal human natural antibodies |
| WO1999029888A1 (en) | 1997-12-05 | 1999-06-17 | The Scripps Research Institute | Humanization of murine antibody |
| US6703020B1 (en) | 1999-04-28 | 2004-03-09 | Board Of Regents, The University Of Texas System | Antibody conjugate methods for selectively inhibiting VEGF |
| AU784983B2 (en) | 1999-12-15 | 2006-08-17 | Genentech Inc. | Shotgun scanning, a combinatorial method for mapping functional protein epitopes |
| EP1276702A2 (en) | 2000-03-31 | 2003-01-22 | Genentech, Inc. | Compositions and methods for detecting and quantifying gene expression |
| US6596541B2 (en) | 2000-10-31 | 2003-07-22 | Regeneron Pharmaceuticals, Inc. | Methods of modifying eukaryotic cells |
| EP1916303B1 (en) | 2000-11-30 | 2013-02-27 | Medarex, Inc. | Nucleic acids encoding rearranged human immunoglobulin sequences from transgenic transchromosomal mice |
| AU2002256971B2 (en) | 2000-12-28 | 2008-04-03 | Altus Pharmaceuticals Inc. | Crystals of whole antibodies and fragments thereof and methods for making and using them |
| CA2488441C (en) | 2002-06-03 | 2015-01-27 | Genentech, Inc. | Synthetic antibody phage libraries |
| EP1585767A2 (en) | 2003-01-16 | 2005-10-19 | Genentech, Inc. | Synthetic antibody phage libraries |
| US20050186208A1 (en) | 2003-05-30 | 2005-08-25 | Genentech, Inc. | Treatment with anti-VEGF antibodies |
| ES2786568T3 (en) | 2003-07-28 | 2020-10-13 | Genentech Inc | Reduction of protein A leaching during protein A affinity chromatography |
| WO2005044853A2 (en) | 2003-11-01 | 2005-05-19 | Genentech, Inc. | Anti-vegf antibodies |
| US20050106667A1 (en) | 2003-08-01 | 2005-05-19 | Genentech, Inc | Binding polypeptides with restricted diversity sequences |
| MXPA06011199A (en) | 2004-03-31 | 2007-04-16 | Genentech Inc | Humanized anti-tgf-beta antibodies. |
| US7785903B2 (en) | 2004-04-09 | 2010-08-31 | Genentech, Inc. | Variable domain library and uses |
| US20060008823A1 (en) | 2004-05-12 | 2006-01-12 | Kemp Jennifer T | DNA profiling and SNP detection utilizing microarrays |
| US20060009360A1 (en) | 2004-06-25 | 2006-01-12 | Robert Pifer | New adjuvant composition |
| EP1957531B1 (en) | 2005-11-07 | 2016-04-13 | Genentech, Inc. | Binding polypeptides with diversified and consensus vh/vl hypervariable sequences |
| US20070237764A1 (en) | 2005-12-02 | 2007-10-11 | Genentech, Inc. | Binding polypeptides with restricted diversity sequences |
| KR20080087822A (en) | 2005-12-16 | 2008-10-01 | 제넨테크, 인크. | How to diagnose, predict, and treat glioma |
| AR060871A1 (en) | 2006-05-09 | 2008-07-16 | Genentech Inc | UNION OF POLYPEPTIDES WITH OPTIMIZED SUPERCONTIGES |
| CA2679943A1 (en) | 2007-03-02 | 2008-09-12 | Board Of Regents, The University Of Texas System | Multigene assay to predict outcome in an individual with glioblastoma |
| CN100592373C (en) | 2007-05-25 | 2010-02-24 | 群康科技(深圳)有限公司 | Liquid crystal display panel driving device and driving method thereof |
| ES2547568T3 (en) * | 2007-11-30 | 2015-10-07 | Genentech, Inc. | VEGF polymorphisms and anti-angiogenesis therapy |
| RU2393773C1 (en) * | 2009-04-20 | 2010-07-10 | ФЕДЕРАЛЬНОЕ ГОСУДАРСТВЕННОЕ УЧРЕЖДЕНИЕ РОССИЙСКИЙ НАУЧНЫЙ ЦЕНТР РАДИОЛОГИИ И ХИРУРГИЧЕСКИХ ТЕХНОЛОГИЙ ФЕДЕРАЛЬНОГО АГЕНТСТВА ПО ВЫСОКОТЕХНОЛОГИЧНОЙ МЕДИЦИНСКОЙ ПОМОЩИ (ФГУ "РНЦРХТ Росмедтехнологий") | Method of predicting life duration of patients with glial brain tumours |
| SG175289A1 (en) | 2009-04-20 | 2011-11-28 | Genentech Inc | Adjuvant cancer therapy |
| US20110117083A1 (en) | 2009-08-14 | 2011-05-19 | Genentech, Inc. | Biological markers for monitoring patient response to vegf antagonists |
| RU2012140447A (en) | 2010-02-23 | 2014-03-27 | Дженентек, Инк. | ANTIANGIOGENIC THERAPY FOR TREATMENT OF OVARIAN CANCER |
| AU2011293522B2 (en) | 2010-08-24 | 2015-03-19 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Interleukin-13 receptor alpha 2 peptide-based brain cancer vaccines |
| SG195208A1 (en) | 2011-06-02 | 2013-12-30 | Almac Diagnostics Ltd | Molecular diagnostic test for cancer |
| AU2013207778B2 (en) | 2012-01-13 | 2017-10-12 | Genentech, Inc. | Biological markers for identifying patients for treatment with VEGF antagonists |
| MX2014011582A (en) | 2012-03-30 | 2014-11-21 | Genentech Inc | METHODS AND COMPOSITIONS OF DIAGNOSIS FOR THE TREATMENT OF CANCER. |
| KR20190088571A (en) | 2012-08-07 | 2019-07-26 | 제넨테크, 인크. | Combination therapy for the treatment of glioblastoma |
| SG11201504023SA (en) | 2012-12-03 | 2015-06-29 | Almac Diagnostics Ltd | Molecular diagnostic test for cancer |
| US10617755B2 (en) | 2013-08-30 | 2020-04-14 | Genentech, Inc. | Combination therapy for the treatment of glioblastoma |
| WO2016011052A1 (en) | 2014-07-14 | 2016-01-21 | Genentech, Inc. | Diagnostic methods and compositions for treatment of glioblastoma |
-
2014
- 2014-08-28 US US14/471,734 patent/US10456470B2/en not_active Expired - Fee Related
- 2014-08-29 HK HK16109700.4A patent/HK1221422A1/en unknown
- 2014-08-29 SG SG11201601471SA patent/SG11201601471SA/en unknown
- 2014-08-29 CA CA2921515A patent/CA2921515A1/en not_active Abandoned
- 2014-08-29 CN CN201480053412.XA patent/CN105611940A/en active Pending
- 2014-08-29 KR KR1020167008303A patent/KR20160048196A/en not_active Ceased
- 2014-08-29 AU AU2014312079A patent/AU2014312079B2/en not_active Ceased
- 2014-08-29 JP JP2016537909A patent/JP6664323B2/en not_active Expired - Fee Related
- 2014-08-29 EP EP14839805.0A patent/EP3038646B1/en active Active
- 2014-08-29 WO PCT/US2014/053500 patent/WO2015031808A2/en not_active Ceased
- 2014-08-29 RU RU2016111161A patent/RU2706968C2/en active
- 2014-08-29 BR BR112016004305A patent/BR112016004305A2/en not_active IP Right Cessation
- 2014-08-29 MX MX2016002423A patent/MX2016002423A/en unknown
- 2014-08-29 AR ARP140103244A patent/AR097500A1/en unknown
-
2016
- 2016-02-11 IL IL244089A patent/IL244089A0/en unknown
-
2019
- 2019-11-11 JP JP2019204041A patent/JP2020062012A/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| IL244089A0 (en) | 2016-04-21 |
| HK1221422A1 (en) | 2017-06-02 |
| AU2014312079B2 (en) | 2020-01-16 |
| AU2014312079A1 (en) | 2016-03-03 |
| RU2706968C2 (en) | 2019-11-21 |
| CA2921515A1 (en) | 2015-03-05 |
| KR20160048196A (en) | 2016-05-03 |
| JP2016529903A (en) | 2016-09-29 |
| MX2016002423A (en) | 2016-08-19 |
| EP3038646A4 (en) | 2017-07-12 |
| JP2020062012A (en) | 2020-04-23 |
| WO2015031808A2 (en) | 2015-03-05 |
| US10456470B2 (en) | 2019-10-29 |
| AR097500A1 (en) | 2016-03-16 |
| EP3038646A2 (en) | 2016-07-06 |
| CN105611940A (en) | 2016-05-25 |
| JP6664323B2 (en) | 2020-03-13 |
| EP3038646B1 (en) | 2020-03-04 |
| US20150064178A1 (en) | 2015-03-05 |
| RU2016111161A (en) | 2017-10-05 |
| WO2015031808A3 (en) | 2015-04-23 |
| BR112016004305A2 (en) | 2017-10-17 |
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