SG11201506974XA - Methods for controlling t cell proliferation - Google Patents
Methods for controlling t cell proliferationInfo
- Publication number
- SG11201506974XA SG11201506974XA SG11201506974XA SG11201506974XA SG11201506974XA SG 11201506974X A SG11201506974X A SG 11201506974XA SG 11201506974X A SG11201506974X A SG 11201506974XA SG 11201506974X A SG11201506974X A SG 11201506974XA SG 11201506974X A SG11201506974X A SG 11201506974XA
- Authority
- SG
- Singapore
- Prior art keywords
- controlling
- methods
- cell proliferation
- proliferation
- cell
- Prior art date
Links
- 230000006052 T cell proliferation Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/04—Amoebicides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/7051—T-cell receptor (TcR)-CD3 complex
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70521—CD28, CD152
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3069—Reproductive system, e.g. ovaria, uterus, testes, prostate
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/64—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising a combination of variable region and constant region components
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/33—Fusion polypeptide fusions for targeting to specific cell types, e.g. tissue specific targeting, targeting of a bacterial subspecies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Virology (AREA)
- Genetics & Genomics (AREA)
- Cell Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Pregnancy & Childbirth (AREA)
- Gynecology & Obstetrics (AREA)
- Reproductive Health (AREA)
- Biotechnology (AREA)
- Pulmonology (AREA)
- Obesity (AREA)
- AIDS & HIV (AREA)
- Physical Education & Sports Medicine (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361783445P | 2013-03-14 | 2013-03-14 | |
PCT/US2014/026734 WO2014151960A2 (en) | 2013-03-14 | 2014-03-13 | Methods for controlling t cell proliferation |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11201506974XA true SG11201506974XA (en) | 2015-10-29 |
Family
ID=51569299
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201506974XA SG11201506974XA (en) | 2013-03-14 | 2014-03-13 | Methods for controlling t cell proliferation |
Country Status (10)
Country | Link |
---|---|
US (2) | US9944690B2 (de) |
EP (1) | EP2968502B1 (de) |
JP (3) | JP6541639B2 (de) |
KR (1) | KR20150131218A (de) |
CN (1) | CN105209065B (de) |
AU (2) | AU2014236726A1 (de) |
CA (1) | CA2905352A1 (de) |
HK (1) | HK1217000A1 (de) |
SG (1) | SG11201506974XA (de) |
WO (1) | WO2014151960A2 (de) |
Families Citing this family (104)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2557164A1 (de) | 2003-02-18 | 2013-02-13 | Kevin M. Slawin | Induzierte Aktivierung ein dendritischen Zellen |
EP2331680B1 (de) | 2008-09-22 | 2017-05-03 | Baylor College Of Medicine | Verfahren und zusammensetzungen zur erzeugung einer immunreaktion mittels cd40-induktion sowie strukturerkennungsrezeptoradaptern |
AU2013204922B2 (en) | 2012-12-20 | 2015-05-14 | Celgene Corporation | Chimeric antigen receptors |
ES2776698T3 (es) | 2012-12-20 | 2020-07-31 | Purdue Research Foundation | Células T que expresan un receptor antigénico quimérico como terapia contra el cáncer |
HUE036250T2 (hu) | 2013-02-15 | 2018-06-28 | Univ California | Kiméra antigénreceptor és eljárások az alkalmazására |
US9944690B2 (en) | 2013-03-14 | 2018-04-17 | Bellicum Pharmaceuticals, Inc. | Methods for controlling T cell proliferation |
WO2014152177A1 (en) | 2013-03-15 | 2014-09-25 | Anthrogenesis Corporation | Modified t lymphocytes |
JP6772063B2 (ja) * | 2014-02-14 | 2020-10-21 | ベリカム ファーマシューティカルズ, インコーポレイテッド | 誘導可能なキメラポリペプチドを使用して細胞を活性化するための方法 |
DK3888674T3 (da) | 2014-04-07 | 2024-07-08 | Novartis Ag | Behandling af cancer ved anvendelse af anti-cd19-kimær antigenreceptor |
US10888608B2 (en) | 2014-09-02 | 2021-01-12 | Bellicum Pharmaceuticals, Inc. | Costimulation of chimeric antigen receptors by MyD88 and CD40 polypeptides |
RU2743657C2 (ru) | 2014-10-08 | 2021-02-20 | Новартис Аг | Биомаркеры, прогнозирующие способность к терапевтическому ответу на терапию химерным рецептором антигена, и их применение |
AU2015341481C1 (en) | 2014-11-03 | 2021-09-16 | ACADEMISCH ZIEKENHUIS LEIDEN (h.o.d.n. LUMC) | T cell receptors directed against Bob1 and uses thereof |
JP6720176B2 (ja) * | 2014-12-15 | 2020-07-08 | ベリカム ファーマシューティカルズ, インコーポレイテッド | 治療用細胞のコントロールされた活性化または排除のための方法 |
AU2015362748A1 (en) * | 2014-12-15 | 2017-04-27 | Bellicum Pharmaceuticals, Inc. | Methods for controlled elimination of therapeutic cells |
AU2015374296B2 (en) | 2014-12-29 | 2021-09-02 | Novartis Ag | Methods of making chimeric antigen receptor-expressing cells |
EP3247368A4 (de) | 2015-01-23 | 2019-01-02 | Musc Foundation for Research Development | Zytokinrezeptorgene und verwendung davon zur verbesserung der therapie |
CN107683289B (zh) | 2015-01-26 | 2021-08-06 | 芝加哥大学 | IL13Rα2结合剂和其在癌症治疗中的用途 |
CA2973524A1 (en) | 2015-01-26 | 2016-08-04 | Cellectis | Anti-hsp70 specific chimeric antigen receptors (cars) for cancer immunotherapy |
CN107835820B (zh) | 2015-01-26 | 2021-10-15 | 芝加哥大学 | 识别癌症特异性IL13Rα2的CAR T细胞 |
US10590182B2 (en) | 2015-02-24 | 2020-03-17 | The Regents Of The University Of California | Binding-triggered transcriptional switches and methods of use thereof |
US9777064B2 (en) | 2015-03-17 | 2017-10-03 | Chimera Bioengineering, Inc. | Smart CAR devices, DE CAR polypeptides, side CARs and uses thereof |
HUE059218T2 (hu) | 2015-04-08 | 2022-11-28 | Novartis Ag | CD20-terápiák, CD22-terápiák és kombinációs terápiák CD19 kiméra antigénreceptort (CAR-t) expresszáló sejttel |
ES2948133T3 (es) | 2015-04-17 | 2023-08-31 | Novartis Ag | Métodos para mejorar la eficacia y expansión de células que expresan un receptor de antígeno quimérico |
TWI859112B (zh) | 2015-07-21 | 2024-10-21 | 瑞士商諾華公司 | 改良免疫細胞之功效及擴展之方法 |
GB201513540D0 (en) | 2015-07-31 | 2015-09-16 | King S College London | Therapeutic agents |
HK1257441A1 (zh) | 2015-08-28 | 2019-10-18 | The Trustees Of The University Of Pennsylvania | 表達嵌合細胞內信號傳導分子的細胞的方法和組合物 |
WO2017040195A1 (en) * | 2015-08-28 | 2017-03-09 | The Trustees Of The University Of Pennsylvania | Methods and compositions for cells expressing a chimeric intracellular signaling molecule |
CN108780084B (zh) | 2015-09-03 | 2022-07-22 | 诺华股份有限公司 | 预测细胞因子释放综合征的生物标志物 |
EP3356524B1 (de) * | 2015-09-30 | 2021-08-18 | Vycellix, Inc. | Verbesserte genverabreichung an natürliche killerzellen, hämatopoetische stammzellen und makrophagen |
WO2017070554A1 (en) | 2015-10-23 | 2017-04-27 | Fred Hutchinson Cancer Research Center | Methods to create chemically-induced dimerizing protein systems for regulation of cellular events |
MA44314A (fr) * | 2015-11-05 | 2018-09-12 | Juno Therapeutics Inc | Récepteurs chimériques contenant des domaines induisant traf, et compositions et méthodes associées |
US11052111B2 (en) | 2015-12-08 | 2021-07-06 | Chimera Bioengineering, Inc. | Smart CAR devices and DE CAR polypeptides for treating disease and methods for enhancing immune responses |
CN117402829A (zh) * | 2015-12-14 | 2024-01-16 | 贝里坤制药股份有限公司 | 用于治疗性细胞活化或消除的双重控制 |
EP4477748A3 (de) | 2015-12-28 | 2025-03-12 | Novartis AG | Verfahren zur herstellung von chimären antigenrezeptorexprimierenden zellen |
MX2018008416A (es) | 2016-01-08 | 2019-11-11 | Univ California | Polipéptidos heterodímericos condicionalmente activos y métodos para su uso. |
US11111505B2 (en) | 2016-03-19 | 2021-09-07 | Exuma Biotech, Corp. | Methods and compositions for transducing lymphocytes and regulating the activity thereof |
US11325948B2 (en) | 2016-03-19 | 2022-05-10 | Exuma Biotech Corp. | Methods and compositions for genetically modifying lymphocytes to express polypeptides comprising the intracellular domain of MPL |
BR112018070073A2 (pt) | 2016-04-01 | 2019-02-12 | Kite Pharma, Inc. | receptores de antígeno quimérico e célula t e métodos de uso |
CA3019650C (en) | 2016-04-01 | 2023-07-25 | Kite Pharma, Inc. | Chimeric receptors and methods of use thereof |
AU2017240150C1 (en) | 2016-04-01 | 2022-10-27 | Kite Pharma, Inc. | BCMA binding molecules and methods of use thereof |
SG11201808622SA (en) | 2016-04-01 | 2018-10-30 | Amgen Inc | Chimeric receptors to flt3 and methods of use thereof |
EP3439675A4 (de) | 2016-04-08 | 2019-12-18 | Purdue Research Foundation | Verfahren und zusammensetzungen für car-t-zelltherapie |
WO2017201019A1 (en) | 2016-05-17 | 2017-11-23 | Chimera Bioengineering, Inc. | Methods for making novel antigen binding domains |
US20210177896A1 (en) | 2016-06-02 | 2021-06-17 | Novartis Ag | Therapeutic regimens for chimeric antigen receptor (car)- expressing cells |
US11384156B2 (en) * | 2016-07-25 | 2022-07-12 | The Nemours Foundation | Adoptive T-cell therapy using EMPD-specific chimeric antigen receptors for treating IgE-mediated allergic diseases |
WO2018045177A1 (en) | 2016-09-01 | 2018-03-08 | Chimera Bioengineering, Inc. | Gold optimized car t-cells |
KR102717188B1 (ko) | 2016-10-07 | 2024-10-16 | 노파르티스 아게 | 암의 치료를 위한 키메라 항원 수용체 |
WO2018148224A1 (en) | 2017-02-07 | 2018-08-16 | Seattle Children's Hospital (dba Seattle Children's Research Institute) | Phospholipid ether (ple) car t cell tumor targeting (ctct) agents |
EP3589295B1 (de) | 2017-02-28 | 2024-09-11 | Endocyte, Inc. | Zusammensetzungen und verfahren für car-t-zelltherapie |
JOP20180027A1 (ar) * | 2017-03-28 | 2019-01-30 | Cell Design Labs Inc | بوليبيبتيدات مخلطة و طرق لتغيير موضع الغشاء فيها |
ES2894106T3 (es) * | 2017-04-21 | 2022-02-11 | Safe Implant Tech Aps | Partículas de oro para su uso en la terapia para prevenir o reducir la contractura capsular |
JOP20180042A1 (ar) | 2017-04-24 | 2019-01-30 | Kite Pharma Inc | نطاقات ربط مولد ضد متوافقة مع البشر وطرق الاستخدام |
WO2018208849A1 (en) | 2017-05-09 | 2018-11-15 | Bellicum Pharmaceuticals, Inc. | Methods to augment or alter signal transduction |
CA3063719A1 (en) | 2017-05-19 | 2018-11-22 | The Regents Of The University Of California | Antibody chemically induced dimerizer (abcid) as molecular switches for regulating cellular therapies |
TWI731268B (zh) * | 2017-09-29 | 2021-06-21 | 財團法人國家衛生研究院 | 可增強抗腫瘤與抗病毒t細胞存活與其功能性之方法與組合物 |
KR20200069358A (ko) | 2017-10-25 | 2020-06-16 | 노파르티스 아게 | 키메라 항원 수용체 발현 세포의 제조 방법 |
WO2019099707A1 (en) | 2017-11-16 | 2019-05-23 | Kite Pharma, Inc | Modified chimeric antigen receptors and methods of use |
CA3084190A1 (en) | 2017-12-08 | 2019-06-13 | Bellicum Pharmaceuticals, Inc. | Methods for enhancing and maintaining car-t cell efficacy |
EP3728189A1 (de) | 2017-12-20 | 2020-10-28 | Bellicum Pharmaceuticals, Inc. | Multimere piperidinderivate |
JP7372920B2 (ja) | 2017-12-29 | 2023-11-01 | セレクティス | Car t細胞の作製を改良するための方法 |
US11311576B2 (en) | 2018-01-22 | 2022-04-26 | Seattle Children's Hospital | Methods of use for CAR T cells |
SG11202007426XA (en) | 2018-02-06 | 2020-09-29 | Seattle Childrens Hospital Dba Seattle Childrens Res Inst | Fluorescein-specific cars exhibiting optimal t cell function against fl-ple labelled tumors |
WO2019160815A1 (en) | 2018-02-13 | 2019-08-22 | Chimera Bioengineering, Inc. | Coordinating gene expression using rna destabilizing elements |
US12240870B2 (en) | 2018-02-23 | 2025-03-04 | Purdue Research Foundation | Sequencing method for CAR T cell therapy |
AR114273A1 (es) | 2018-03-02 | 2020-08-12 | Allogene Therapeutics Inc | Receptores inducibles de citoquina quimérica |
EA202092417A1 (ru) | 2018-04-10 | 2021-01-26 | Амген Инк. | Химерные рецепторы к dll3 и способы их применения |
US20210396739A1 (en) | 2018-05-01 | 2021-12-23 | Novartis Ag | Biomarkers for evaluating car-t cells to predict clinical outcome |
WO2019227003A1 (en) | 2018-05-25 | 2019-11-28 | Novartis Ag | Combination therapy with chimeric antigen receptor (car) therapies |
CR20210091A (es) | 2018-07-18 | 2021-03-24 | Amgen Inc | Receptores químericos de steap1 y métodos de uso de los mismos antecedentes de la invención |
US20210163893A1 (en) | 2018-08-09 | 2021-06-03 | Juno Therapeutics, Inc. | Processes for generating engineered cells and compositions thereof |
TWI875709B (zh) | 2018-08-31 | 2025-03-11 | 瑞士商諾華公司 | 製備表現嵌合抗原受體的細胞之方法 |
US20210171909A1 (en) | 2018-08-31 | 2021-06-10 | Novartis Ag | Methods of making chimeric antigen receptor?expressing cells |
US20220047633A1 (en) | 2018-09-28 | 2022-02-17 | Novartis Ag | Cd22 chimeric antigen receptor (car) therapies |
WO2020069409A1 (en) | 2018-09-28 | 2020-04-02 | Novartis Ag | Cd19 chimeric antigen receptor (car) and cd22 car combination therapies |
CN120025452A (zh) | 2018-12-12 | 2025-05-23 | 凯德药业股份有限公司 | 嵌合抗原和t细胞受体及使用的方法 |
CN113518785A (zh) | 2019-03-01 | 2021-10-19 | 艾洛基治疗公司 | 携带pd-1胞外域的嵌合细胞因子受体 |
BR112021016984A2 (pt) | 2019-03-01 | 2021-11-30 | Allogene Therapeutics Inc | Receptores de antígeno quimérico direcionados a dll3 e agentes de ligação |
WO2020180694A1 (en) | 2019-03-01 | 2020-09-10 | Allogene Therapeutics, Inc. | Constitutively active chimeric cytokine receptors |
US20220168389A1 (en) | 2019-04-12 | 2022-06-02 | Novartis Ag | Methods of making chimeric antigen receptor-expressing cells |
US12163153B2 (en) | 2019-04-26 | 2024-12-10 | Allogene Therapeutics, Inc. | Methods of manufacturing allogeneic CAR T cells |
US11896617B2 (en) | 2019-04-26 | 2024-02-13 | Allogene Therapeutics, Inc. | Polynucleotides encoding rituximab-resistant chimeric antigen receptors |
AU2020265749A1 (en) | 2019-05-01 | 2022-01-06 | Juno Therapeutics, Inc. | Cells expressing a chimeric receptor from a modified CD247 locus, related polynucleotides and methods |
AU2020265741A1 (en) | 2019-05-01 | 2021-11-25 | Editas Medicine, Inc. | Cells expressing a recombinant receptor from a modified TGFBR2 Locus, related polynucleotides and methods |
JP2019170393A (ja) * | 2019-06-19 | 2019-10-10 | 国立大学法人九州大学 | iPS細胞の作製方法 |
AU2020334884A1 (en) | 2019-08-18 | 2022-02-17 | Chimera Bioengineering, Inc. | Combination therapy with gold controlled transgenes |
EP4104187A1 (de) | 2020-02-14 | 2022-12-21 | Novartis AG | Verfahren zur vorhersage des ansprechens auf eine chimäre antigen-rezeptor-therapie |
CA3167065A1 (en) | 2020-02-24 | 2021-09-02 | Regina Junhui LIN | Bcma car-t cells with enhanced activities |
BR112022017148A2 (pt) | 2020-02-27 | 2022-11-08 | Novartis Ag | Métodos para produzir células que expressam receptor de antígeno quimérico |
JP2023531531A (ja) | 2020-06-26 | 2023-07-24 | ジュノ セラピューティクス ゲーエムベーハー | 組換え受容体を条件付きで発現する操作されたt細胞、関連ポリヌクレオチド、および方法 |
WO2022010798A1 (en) | 2020-07-06 | 2022-01-13 | Kiromic BioPharma, Inc. | Mesothelin isoform binding molecules and chimeric pd1 receptor molecules, cells containing the same and uses thereof |
IL299886A (en) | 2020-07-17 | 2023-03-01 | Instil Bio Uk Ltd | Receptors that provide targeted costimulation for host cell therapy |
CN116635062A (zh) | 2020-11-13 | 2023-08-22 | 诺华股份有限公司 | 使用表达嵌合抗原受体(car)的细胞的组合疗法 |
CA3202233A1 (en) | 2020-11-18 | 2022-05-27 | Kiromic BioPharma, Inc. | Gamma-delta t cell manufacturing processes and chimeric pd1 receptor molecules |
EP4251742A4 (de) | 2020-11-24 | 2025-01-08 | Lyell Immunopharma, Inc. | Verfahren zur herstellung, zusammensetzungen damit und verfahren zur verwendung von regenerierten t-zellen |
AU2021409801A1 (en) | 2020-12-21 | 2023-06-22 | Allogene Therapeutics, Inc. | Protease-activating cd45-gate car |
US11945876B2 (en) | 2021-06-16 | 2024-04-02 | Instil Bio (Uk) Limited | Receptors providing targeted costimulation for adoptive cell therapy |
WO2023288278A1 (en) * | 2021-07-16 | 2023-01-19 | Instil Bio (Uk) Limited | Chimeric molecules providing targeted costimulation for adoptive cell therapy |
EP4376876A1 (de) | 2021-07-26 | 2024-06-05 | Kite Pharma, Inc. | Geteilte chimäre antigenrezeptoren und verfahren zur verwendung |
CN114410689B (zh) * | 2022-03-29 | 2022-06-17 | 北京循生生物医学研究有限公司 | 一种增强肿瘤浸润淋巴细胞杀伤力的制备方法 |
TW202423983A (zh) | 2022-09-15 | 2024-06-16 | 瑞士商諾華公司 | 使用嵌合抗原受體療法的自體免疫性障礙的治療 |
TW202440623A (zh) | 2022-11-28 | 2024-10-16 | 美商艾洛基因醫療公司 | 靶向密連蛋白18﹒2之嵌合抗原受體及結合劑以及其用途 |
CN116179495B (zh) * | 2022-11-28 | 2025-06-06 | 上海恩凯细胞技术有限公司 | 转基因免疫细胞及其应用 |
WO2024182539A1 (en) | 2023-02-28 | 2024-09-06 | Lyell Immunopharma, Inc. | Methods of culturing reprogrammed cells |
WO2024196796A1 (en) * | 2023-03-17 | 2024-09-26 | Cartesian Therapeutics, Inc. | Intracellular signaling and costimulatory domains adapted for prolonged expression of chimeric antigen receptors |
Family Cites Families (83)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4514506A (en) | 1982-02-23 | 1985-04-30 | The Government Of The United States As Represented By The Secretary Of The Department Of Health And Human Services | Method for the identification and purification of human lung tumor-associated antigens (hLTAA) and clinical detection and determination of these antigens |
EP0273085A1 (de) | 1986-12-29 | 1988-07-06 | IntraCel Corporation | Verfahren zur Einführung fremder Nukleinsäuren in eukaryotische Zellen |
FR2610631B1 (fr) | 1987-02-09 | 1989-11-24 | Pasteur Institut | Molecules comportant au moins une sequence peptidique porteuse d'un ou plusieurs, epitope caracteristique d'une proteine produite par p. falciparum dans les hepatocytes, et leurs utilisations, notamment pour le diagnostic du paludisme ou dans des compositions de vaccins contre le paludisme |
US5869608A (en) | 1989-03-17 | 1999-02-09 | The United States Of America As Represented By The Department Of Health And Human Services | Nucleotide and amino acid sequences of the four variable domains of the major outer membrane proteins of Chlamydia trachomatis |
US5550318A (en) | 1990-04-17 | 1996-08-27 | Dekalb Genetics Corporation | Methods and compositions for the production of stably transformed, fertile monocot plants and cells thereof |
US5484956A (en) | 1990-01-22 | 1996-01-16 | Dekalb Genetics Corporation | Fertile transgenic Zea mays plant comprising heterologous DNA encoding Bacillus thuringiensis endotoxin |
US5384253A (en) | 1990-12-28 | 1995-01-24 | Dekalb Genetics Corporation | Genetic transformation of maize cells by electroporation of cells pretreated with pectin degrading enzymes |
GB9105383D0 (en) | 1991-03-14 | 1991-05-01 | Immunology Ltd | An immunotherapeutic for cervical cancer |
CA2067031C (en) | 1991-04-26 | 2003-02-18 | Shigekazu Nagata | Dna coding for human cell surface antigen |
US5780036A (en) | 1991-08-26 | 1998-07-14 | The Scripps Research Institute | Peptides for inducing cytotoxic T lymphocyte responses to hepattis B virus |
US5610042A (en) | 1991-10-07 | 1997-03-11 | Ciba-Geigy Corporation | Methods for stable transformation of wheat |
DE4228457A1 (de) | 1992-08-27 | 1994-04-28 | Beiersdorf Ag | Herstellung von heterodimerem PDGF-AB mit Hilfe eines bicistronischen Vektorsystems in Säugerzellen |
GB9222888D0 (en) | 1992-10-30 | 1992-12-16 | British Tech Group | Tomography |
US5869337A (en) | 1993-02-12 | 1999-02-09 | President And Fellows Of Harvard College | Regulated transcription of targeted genes and other biological events |
US5834266A (en) | 1993-02-12 | 1998-11-10 | President & Fellows Of Harvard College | Regulated apoptosis |
PL310327A1 (en) | 1993-02-12 | 1995-12-11 | Univ Leland Stanford Junior | Adjustable transcription of target genes and other biological processes |
US5830462A (en) | 1993-02-12 | 1998-11-03 | President & Fellows Of Harvard College | Regulated transcription of targeted genes and other biological events |
US5426027A (en) | 1993-05-20 | 1995-06-20 | The Government Of The United States Of America As Represented By The Secretary | Nucleic acid probes and methods for detecting Candida DNA cells in blood |
US5648226A (en) | 1993-07-22 | 1997-07-15 | Ludwig Institute For Cancer Research | Isolated peptides derived from tumor rejection antigens, and their use |
WO1995004542A1 (en) | 1993-08-06 | 1995-02-16 | Cytel Corporation | Cloning and characterization of the complete mage-1 gene |
US5550214A (en) | 1994-02-10 | 1996-08-27 | Brigham And Women's Hospital | Isolated antigenic oncogene peptide fragments and uses |
US5709995A (en) | 1994-03-17 | 1998-01-20 | The Scripps Research Institute | Hepatitis C virus-derived peptides capable of inducing cytotoxic T lymphocyte responses |
FR2722208B1 (fr) | 1994-07-05 | 1996-10-04 | Inst Nat Sante Rech Med | Nouveau site interne d'entree des ribosomes, vecteur le contenant et utilisation therapeutique |
JPH11511643A (ja) | 1994-10-25 | 1999-10-12 | ザ・ボード・オブ・トラスティーズ・オブ・ザ・リランド・スタンフォード・ジュニア・ユニバーシティ | 遺伝子工学処理された細胞の条件的形質転換 |
US6077947A (en) | 1995-02-02 | 2000-06-20 | Cell Genesys, Inc. | DNA encoding an intracellular chimeric receptor comprising Janus kinase |
US5840839A (en) | 1996-02-09 | 1998-11-24 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Alternative open reading frame DNA of a normal gene and a novel human cancer antigen encoded therein |
US5853719A (en) | 1996-04-30 | 1998-12-29 | Duke University | Methods for treating cancers and pathogen infections using antigen-presenting cells loaded with RNA |
NZ333607A (en) | 1996-07-10 | 2000-08-25 | Immunex Corp | Method of stimulating the immune system by transfecting dendritic cells |
US5955596A (en) | 1996-07-26 | 1999-09-21 | American Cyanamid Company | NucA protein of Haemophilus influenzae and the gene encoding that protein |
US6046158A (en) | 1996-12-20 | 2000-04-04 | Board Of Regents The University Of Texas Systems | Unique dendritic cell-associated C-type lectins, dectin-1 and dectin-2; compositions and uses thereof |
US5965242A (en) | 1997-02-19 | 1999-10-12 | Eastman Kodak Company | Glow-in-the-dark medium and method of making |
US6969609B1 (en) | 1998-12-09 | 2005-11-29 | The United States Of America As Represented By The Department Of Health And Human Serivces | Recombinant vector expressing multiple costimulatory molecules and uses thereof |
US6558951B1 (en) | 1999-02-11 | 2003-05-06 | 3M Innovative Properties Company | Maturation of dendritic cells with immune response modifying compounds |
GB9930616D0 (en) | 1999-12-24 | 2000-02-16 | Mathilda & Terence Kennedy Ins | Activation and inhibition of the immune system |
EP1254953A4 (de) | 1999-12-28 | 2004-06-02 | Toyoshima Kumao | Reife auslösendes agenz für unreife dendritische zellen |
US7435585B2 (en) | 2000-01-03 | 2008-10-14 | University Of Pennsylvania | Auto-stimulating cells and methods for making and using the same |
SE0001642D0 (sv) | 2000-05-04 | 2000-05-04 | Sahltech Ab | Reagent for detection of biomolecules, and use thereof |
US20030232055A1 (en) | 2000-07-31 | 2003-12-18 | Ruslan Medzhitov | Innate immune system-directed vaccines |
WO2002012285A2 (en) | 2000-08-10 | 2002-02-14 | Board Of Regents, The University Of Texas System | The tumor suppressor car-1 |
US7666424B2 (en) * | 2001-10-17 | 2010-02-23 | Sloan-Kettering Institute For Cancer Research | Methods of preparing and using single chain anti-tumor antibodies |
AU2002221780A1 (en) | 2000-10-31 | 2002-05-15 | F.Hoffmann-La Roche Ag | Nucleic acids encoding cd40/cd40l chimeric polypeptides, methods for their production and uses thereof |
US6965023B2 (en) | 2000-11-17 | 2005-11-15 | The Burnham Institute | Death domain proteins |
US6838263B2 (en) | 2001-07-09 | 2005-01-04 | Oklahoma Medical Research Foundation | Targeted fusion proteins and methods for the characterization of cellular membrane domains |
US20040116333A1 (en) | 2001-08-03 | 2004-06-17 | Rong-Hwa Lin | Modulators of P-selectin glycoprotein ligand 1 |
WO2003024480A2 (en) | 2001-09-14 | 2003-03-27 | Cytos Biotechnology Ag | In vivo activation of antigen presenting cells for enhancement of immune responses induced by virus like particles |
US20050215472A1 (en) | 2001-10-23 | 2005-09-29 | Psma Development Company, Llc | PSMA formulations and uses thereof |
WO2003035003A2 (en) | 2001-10-26 | 2003-05-01 | Cleveland Clinic Foundation | Fused cells, methods of forming same, and therapie utilizing same |
GB0225279D0 (en) | 2002-10-30 | 2002-12-11 | Celltech R&D Ltd | Biological products |
EP2557164A1 (de) | 2003-02-18 | 2013-02-13 | Kevin M. Slawin | Induzierte Aktivierung ein dendritischen Zellen |
US20050113564A1 (en) | 2003-11-05 | 2005-05-26 | St. Jude Children's Research Hospital | Chimeric receptors with 4-1BB stimulatory signaling domain |
WO2007050095A2 (en) | 2004-11-19 | 2007-05-03 | The Trustees Of The University Of Pennsylvania | Improved vaccines and methods for using the same |
US8088908B2 (en) | 2005-05-10 | 2012-01-03 | City Of Hope | Humanized anti-prostate stem cell antigen monoclonal antibody |
KR100705981B1 (ko) | 2005-10-12 | 2007-04-10 | 주식회사 리제론 | 인간 성장호르몬을 포함하는 탈모방지 또는 발모촉진용조성물 |
US20100196336A1 (en) | 2006-05-23 | 2010-08-05 | Dongsu Park | Modified dendritic cells having enhanced survival and immunogenicity and related compositions and methods |
WO2008045437A2 (en) * | 2006-10-09 | 2008-04-17 | The General Hospital Corporation | Chimeric t-cell receptors and t-cells targeting egfrviii on tumors |
WO2008049113A2 (en) * | 2006-10-19 | 2008-04-24 | Baylor College Of Medicine | Generating an immune response by inducing cd40 and pattern recognition receptors |
SG187482A1 (en) | 2007-11-07 | 2013-02-28 | Celldex Therapeutics Inc | Antibodies that bind human dendritic and epithelial cell 205 (dec-205) |
WO2009111507A1 (en) | 2008-03-03 | 2009-09-11 | Dyax Corp. | Metalloproteinase 12 binding proteins |
PT3006459T (pt) * | 2008-08-26 | 2021-11-26 | Hope City | Método e composições para funcionamento melhorado de efetores antitumorais de células t |
EP2331680B1 (de) | 2008-09-22 | 2017-05-03 | Baylor College Of Medicine | Verfahren und zusammensetzungen zur erzeugung einer immunreaktion mittels cd40-induktion sowie strukturerkennungsrezeptoradaptern |
CA2795947A1 (en) | 2010-04-16 | 2011-10-20 | Bellicum Pharmaceuticals, Inc. | Method for treating solid tumors |
US9089520B2 (en) | 2010-05-21 | 2015-07-28 | Baylor College Of Medicine | Methods for inducing selective apoptosis |
PH12013501201A1 (en) | 2010-12-09 | 2013-07-29 | Univ Pennsylvania | Use of chimeric antigen receptor-modified t cells to treat cancer |
EP3693017A1 (de) * | 2010-12-14 | 2020-08-12 | University of Maryland, Baltimore | Universelle chimäre anti-tag-antigen-rezeptor-expressions-t-zellen und verfahren zur behandlung von krebs |
WO2012127464A2 (en) | 2011-03-23 | 2012-09-27 | Gavish-Galilee Bio Applications Ltd | Constitutively activated t cells for use in adoptive cell therapy |
US20130071414A1 (en) * | 2011-04-27 | 2013-03-21 | Gianpietro Dotti | Engineered cd19-specific t lymphocytes that coexpress il-15 and an inducible caspase-9 based suicide gene for the treatment of b-cell malignancies |
EP3326467B1 (de) * | 2011-09-16 | 2020-03-11 | Baylor College of Medicine | Gegen die tumormikroumgebung gerichtete manipulierte nkt-zellen |
WO2013067492A1 (en) * | 2011-11-03 | 2013-05-10 | The Trustees Of The University Of Pennsylvania | Isolated b7-h4 specific compositions and methods of use thereof |
US8945876B2 (en) | 2011-11-23 | 2015-02-03 | University Of Hawaii | Auto-processing domains for polypeptide expression |
WO2013126720A2 (en) | 2012-02-22 | 2013-08-29 | The Trustees Of The University Of Pennsylvania | Compositions and methods for the assessment of target cancer cell resistance to car engineered t cell killing |
CN110295186A (zh) | 2012-04-11 | 2019-10-01 | 美国卫生和人力服务部 | 靶向b-细胞成熟抗原的嵌合抗原受体 |
US20130280220A1 (en) * | 2012-04-20 | 2013-10-24 | Nabil Ahmed | Chimeric antigen receptor for bispecific activation and targeting of t lymphocytes |
EP2844282B1 (de) | 2012-05-04 | 2019-06-12 | Pfizer Inc | Prostata-assoziierte antigene und immuntherapieschemata auf impfstoffbasis |
AU2013266733B2 (en) * | 2012-05-25 | 2018-07-05 | Cellectis | Methods for engineering allogeneic and immunosuppressive resistant T cell for immunotherapy |
WO2014059173A2 (en) * | 2012-10-10 | 2014-04-17 | Sangamo Biosciences, Inc. | T cell modifying compounds and uses thereof |
HUE036250T2 (hu) | 2013-02-15 | 2018-06-28 | Univ California | Kiméra antigénreceptor és eljárások az alkalmazására |
US9434935B2 (en) | 2013-03-10 | 2016-09-06 | Bellicum Pharmaceuticals, Inc. | Modified caspase polypeptides and uses thereof |
US9944690B2 (en) | 2013-03-14 | 2018-04-17 | Bellicum Pharmaceuticals, Inc. | Methods for controlling T cell proliferation |
DK3004329T3 (da) | 2013-06-05 | 2020-05-18 | Bellicum Pharmaceuticals Inc | Fremgangsmåder til induktion af delvis apoptose under anvendelse af caspasepolypeptider |
US10144770B2 (en) | 2013-10-17 | 2018-12-04 | National University Of Singapore | Chimeric receptors and uses thereof in immune therapy |
JP6772063B2 (ja) | 2014-02-14 | 2020-10-21 | ベリカム ファーマシューティカルズ, インコーポレイテッド | 誘導可能なキメラポリペプチドを使用して細胞を活性化するための方法 |
EP3114217A4 (de) | 2014-03-07 | 2017-09-20 | Bellicum Pharmaceuticals, Inc. | Caspasepolypeptide mit modifizierter aktivität und verwendungen davon |
US10888608B2 (en) | 2014-09-02 | 2021-01-12 | Bellicum Pharmaceuticals, Inc. | Costimulation of chimeric antigen receptors by MyD88 and CD40 polypeptides |
-
2014
- 2014-03-13 US US14/210,034 patent/US9944690B2/en active Active
- 2014-03-13 JP JP2016502228A patent/JP6541639B2/ja active Active
- 2014-03-13 WO PCT/US2014/026734 patent/WO2014151960A2/en active Application Filing
- 2014-03-13 EP EP14770399.5A patent/EP2968502B1/de active Active
- 2014-03-13 SG SG11201506974XA patent/SG11201506974XA/en unknown
- 2014-03-13 KR KR1020157028844A patent/KR20150131218A/ko not_active Ceased
- 2014-03-13 CN CN201480028439.3A patent/CN105209065B/zh active Active
- 2014-03-13 AU AU2014236726A patent/AU2014236726A1/en not_active Abandoned
- 2014-03-13 HK HK16105044.7A patent/HK1217000A1/zh unknown
- 2014-03-13 CA CA2905352A patent/CA2905352A1/en not_active Abandoned
-
2018
- 2018-03-02 US US15/910,380 patent/US20180265566A1/en not_active Abandoned
- 2018-05-31 JP JP2018105044A patent/JP2018145194A/ja not_active Withdrawn
-
2019
- 2019-03-07 AU AU2019201586A patent/AU2019201586A1/en not_active Abandoned
- 2019-12-13 JP JP2019225565A patent/JP2020055863A/ja not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
CN105209065B (zh) | 2020-07-31 |
CA2905352A1 (en) | 2014-09-25 |
EP2968502A4 (de) | 2016-10-19 |
JP2016519068A (ja) | 2016-06-30 |
AU2014236726A1 (en) | 2015-09-17 |
EP2968502B1 (de) | 2020-08-26 |
US20140286987A1 (en) | 2014-09-25 |
KR20150131218A (ko) | 2015-11-24 |
EP2968502A2 (de) | 2016-01-20 |
AU2019201586A1 (en) | 2019-03-28 |
JP6541639B2 (ja) | 2019-07-10 |
CN105209065A (zh) | 2015-12-30 |
HK1217000A1 (zh) | 2016-12-16 |
JP2020055863A (ja) | 2020-04-09 |
WO2014151960A3 (en) | 2015-02-05 |
WO2014151960A2 (en) | 2014-09-25 |
JP2018145194A (ja) | 2018-09-20 |
US9944690B2 (en) | 2018-04-17 |
US20180265566A1 (en) | 2018-09-20 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
SG11201506974XA (en) | Methods for controlling t cell proliferation | |
IL241627B (en) | A method for t-cell activation | |
IL245572B (en) | cell | |
IL244320B (en) | Methods for implementing specific access control | |
IL240484A0 (en) | Gases for process control | |
EP2972645A4 (de) | Steuerungssystem zur leistungsregelung | |
AU353429S (en) | Controller | |
GB201308088D0 (en) | Control | |
PL2970845T3 (pl) | Bioreaktor | |
GB201310031D0 (en) | Cell | |
GB201317883D0 (en) | Control method | |
GB201312332D0 (en) | Cell locations | |
GB2526997B (en) | Controller | |
PL2978839T3 (pl) | Sposób hodowli komórek | |
EP3031901A4 (de) | Kulturvorrichtung | |
GB2501418B (en) | Automatically adjusting gravity-equilibrator | |
SG11201507338PA (en) | Method for culturing cells | |
GB201312803D0 (en) | Cell component | |
GB2517585B (en) | Control arrangement | |
PT2968457T (pt) | Fator h para transplante | |
EP2952987A4 (de) | Steuerung | |
GB201310354D0 (en) | Method for cell differentiation | |
GB201320573D0 (en) | T Cell | |
GB201317413D0 (en) | Controller | |
GB201309797D0 (en) | Apparatus control |