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SG11201505862TA - Spiro-lactam nmda receptor modulators and uses thereof - Google Patents

Spiro-lactam nmda receptor modulators and uses thereof

Info

Publication number
SG11201505862TA
SG11201505862TA SG11201505862TA SG11201505862TA SG11201505862TA SG 11201505862T A SG11201505862T A SG 11201505862TA SG 11201505862T A SG11201505862T A SG 11201505862TA SG 11201505862T A SG11201505862T A SG 11201505862TA SG 11201505862T A SG11201505862T A SG 11201505862TA
Authority
SG
Singapore
Prior art keywords
spiro
nmda receptor
receptor modulators
lactam nmda
lactam
Prior art date
Application number
SG11201505862TA
Inventor
John A Lowe
M Amin Khan
Original Assignee
Naurex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=50071824&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SG11201505862T(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Naurex Inc filed Critical Naurex Inc
Publication of SG11201505862TA publication Critical patent/SG11201505862TA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/10—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epidemiology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Dermatology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
SG11201505862TA 2013-01-29 2014-01-29 Spiro-lactam nmda receptor modulators and uses thereof SG11201505862TA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361757942P 2013-01-29 2013-01-29
PCT/US2014/013639 WO2014120800A1 (en) 2013-01-29 2014-01-29 Spiro-lactam nmda receptor modulators and uses thereof

Publications (1)

Publication Number Publication Date
SG11201505862TA true SG11201505862TA (en) 2015-08-28

Family

ID=50071824

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201505862TA SG11201505862TA (en) 2013-01-29 2014-01-29 Spiro-lactam nmda receptor modulators and uses thereof

Country Status (16)

Country Link
US (2) US9708335B2 (en)
EP (1) EP2951185B1 (en)
JP (1) JP2016506962A (en)
KR (1) KR20150110784A (en)
CN (1) CN105308049A (en)
AU (1) AU2014212501A1 (en)
BR (1) BR112015018094A2 (en)
CA (1) CA2899191A1 (en)
EA (1) EA201591405A1 (en)
ES (1) ES2618421T3 (en)
IL (1) IL240164A0 (en)
MX (1) MX2015009785A (en)
PE (1) PE20151436A1 (en)
PH (1) PH12015501598A1 (en)
SG (1) SG11201505862TA (en)
WO (1) WO2014120800A1 (en)

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LT3514158T (en) 2013-01-29 2023-02-10 Aptinyx Inc. Spiro-lactam nmda receptor modulators and uses thereof
SG11201505862TA (en) 2013-01-29 2015-08-28 Naurex Inc Spiro-lactam nmda receptor modulators and uses thereof
PE20151427A1 (en) 2013-01-29 2015-10-10 Naurex Inc SPIRO-LACTAMA NMDA RECEIVER MODULATORS AND THEIR USES
MX2015009773A (en) * 2013-01-29 2016-08-05 Aptinyx Inc Spiro-lactam nmda receptor modulators and uses thereof.
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AU2017306164B2 (en) 2016-08-01 2021-10-21 Tenacia Biotechnology (Hong Kong) Co., Limited Spiro-lactam NMDA modulators and methods of using same
IL286107B2 (en) * 2016-08-01 2024-09-01 Aptinyx Inc Spiro-lactam NMDA receptor modulators and their uses
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WO2019152688A1 (en) * 2018-01-31 2019-08-08 Aptinyx Inc. Spiro-lactam nmda receptor modulators and uses thereof
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WO2019152696A1 (en) * 2018-01-31 2019-08-08 Aptinyx Inc. Spiro-lactam nmda receptor modulators and uses thereof
EP3746442A1 (en) * 2018-01-31 2020-12-09 Aptinyx Inc. Spiro-lactam nmda receptor modulators and uses thereof
WO2019152685A1 (en) * 2018-01-31 2019-08-08 Aptinyx Inc. Spiro-lactam nmda receptor modulators and methods of using same
JP7667097B2 (en) 2019-06-14 2025-04-22 ヤンセン ファーマシューティカ エヌ．ベー． Substituted pyrazolo-pyridine amides and their use as glun2b receptor modulators - Patents.com
JP2022536773A (en) 2019-06-14 2022-08-18 ヤンセン ファーマシューティカ エヌ．ベー． Substituted pyrazolopyrazines and their use as GLUN2B receptor modulators
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Also Published As

Publication number Publication date
AU2014212501A1 (en) 2015-07-30
IL240164A0 (en) 2015-09-24
JP2016506962A (en) 2016-03-07
EP2951185B1 (en) 2016-12-21
US20150368254A1 (en) 2015-12-24
WO2014120800A1 (en) 2014-08-07
US10316041B2 (en) 2019-06-11
KR20150110784A (en) 2015-10-02
EP2951185A1 (en) 2015-12-09
CA2899191A1 (en) 2014-08-07
US20180127430A1 (en) 2018-05-10
US9708335B2 (en) 2017-07-18
ES2618421T3 (en) 2017-06-21
PE20151436A1 (en) 2015-10-10
BR112015018094A2 (en) 2017-07-18
EA201591405A1 (en) 2017-05-31
CN105308049A (en) 2016-02-03
PH12015501598A1 (en) 2015-10-19
MX2015009785A (en) 2016-04-04

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