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SG11201404979RA - Thermosensitive nanoparticle formulations and method of making the same - Google Patents

Thermosensitive nanoparticle formulations and method of making the same

Info

Publication number
SG11201404979RA
SG11201404979RA SG11201404979RA SG11201404979RA SG11201404979RA SG 11201404979R A SG11201404979R A SG 11201404979RA SG 11201404979R A SG11201404979R A SG 11201404979RA SG 11201404979R A SG11201404979R A SG 11201404979RA SG 11201404979R A SG11201404979R A SG 11201404979RA
Authority
SG
Singapore
Prior art keywords
making
same
nanoparticle formulations
thermosensitive
thermosensitive nanoparticle
Prior art date
Application number
SG11201404979RA
Other languages
English (en)
Inventor
Robert A Reed
Daishui Su
Original Assignee
Celsion Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Celsion Corp filed Critical Celsion Corp
Publication of SG11201404979RA publication Critical patent/SG11201404979RA/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1277—Preparation processes; Proliposomes
    • A61K9/1278—Post-loading, e.g. by ion or pH gradient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SG11201404979RA 2012-02-17 2013-02-15 Thermosensitive nanoparticle formulations and method of making the same SG11201404979RA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261600418P 2012-02-17 2012-02-17
PCT/US2013/026453 WO2013123407A1 (fr) 2012-02-17 2013-02-15 Formulations de nanoparticules thermosensibles et leur procédé de fabrication

Publications (1)

Publication Number Publication Date
SG11201404979RA true SG11201404979RA (en) 2014-10-30

Family

ID=48984771

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201404979RA SG11201404979RA (en) 2012-02-17 2013-02-15 Thermosensitive nanoparticle formulations and method of making the same

Country Status (16)

Country Link
US (2) US20130230457A1 (fr)
EP (1) EP2814464B1 (fr)
JP (3) JP2015507019A (fr)
KR (1) KR102161271B1 (fr)
CN (2) CN104203216A (fr)
AR (1) AR090080A1 (fr)
AU (1) AU2013221292A1 (fr)
CA (1) CA2864469C (fr)
ES (1) ES2773299T3 (fr)
HK (1) HK1200733A1 (fr)
MX (1) MX2014009827A (fr)
PH (1) PH12014501866A1 (fr)
RU (1) RU2014133467A (fr)
SG (1) SG11201404979RA (fr)
TW (2) TWI684463B (fr)
WO (1) WO2013123407A1 (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2971010B1 (fr) 2013-03-14 2020-06-10 ModernaTX, Inc. Formulation et administration de compositions de nucléosides, de nucléotides, et d'acides nucléiques modifiés
US20160194368A1 (en) 2013-09-03 2016-07-07 Moderna Therapeutics, Inc. Circular polynucleotides
JP2016530294A (ja) 2013-09-03 2016-09-29 モデルナ セラピューティクス インコーポレイテッドＭｏｄｅｒｎａ Ｔｈｅｒａｐｅｕｔｉｃｓ，Ｉｎｃ． キメラポリヌクレオチド
US20170210788A1 (en) 2014-07-23 2017-07-27 Modernatx, Inc. Modified polynucleotides for the production of intrabodies
PT3291797T (pt) * 2015-05-04 2020-10-19 Versantis AG Método para preparar vesículas de gradiente de ph transmembranar
GB201509934D0 (en) * 2015-06-08 2015-07-22 King S College London Nanoparticles
TWI678213B (zh) * 2015-07-22 2019-12-01 美商史倍壯製藥公司 用於長春新鹼硫酸鹽脂質體注射之即可使用的調配物
CN105078892B (zh) * 2015-09-06 2018-05-01 重庆医科大学 阿苯达唑热敏脂质体的制备方法
JP6564873B2 (ja) 2015-11-02 2019-08-21 富士フイルム株式会社 リポソーム組成物およびその製造方法

Family Cites Families (24)

* Cited by examiner, † Cited by third party
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US4880635B1 (en) * 1984-08-08 1996-07-02 Liposome Company Dehydrated liposomes
IT1230505B (it) * 1988-10-11 1991-10-25 Sicor Spa Procedimento per la conversione della daunorubicina in doxorubicina.
US5013556A (en) * 1989-10-20 1991-05-07 Liposome Technology, Inc. Liposomes with enhanced circulation time
US6214388B1 (en) * 1994-11-09 2001-04-10 The Regents Of The University Of California Immunoliposomes that optimize internalization into target cells
WO1998017256A1 (fr) * 1996-10-22 1998-04-30 Dmitri Kirpotin Liposomes charges de composes et leurs procedes de preparation
US6726925B1 (en) 1998-06-18 2004-04-27 Duke University Temperature-sensitive liposomal formulation
US6200598B1 (en) * 1998-06-18 2001-03-13 Duke University Temperature-sensitive liposomal formulation
US6593308B2 (en) * 1999-12-03 2003-07-15 The Regents Of The University Of California Targeted drug delivery with a hyaluronan ligand
AU2001234670B2 (en) * 2000-01-28 2005-05-19 Alza Corporation Liposomes containing an entrapped compound in supersaturated solution
US20020028237A1 (en) * 2000-04-20 2002-03-07 Colbern Gail T. Method for reducing toxicity of a cytotoxic agent
US8980310B2 (en) * 2002-12-31 2015-03-17 Bharat Serums and Vaccines, Ltd. Non-pegylated long-circulating liposomes
JP2007522085A (ja) * 2003-06-27 2007-08-09 スミスクライン・ビーチャム・コーポレイション 安定化されたトポテカンリポソーム組成物および方法
EP1689364A4 (fr) * 2003-11-20 2008-10-29 Ym Biosciences Inc Compositions liposomales stables comprenant une amine lipophile contenant des agents pharmaceutiques
AU2005303389A1 (en) * 2004-11-15 2006-05-18 Yissum Research Development Company Of The Hebrew University Of Jerusalem Combination therapy associating preferably a ceramide with a cytotoxic drug
US20060127467A1 (en) * 2004-12-14 2006-06-15 Watkin Kenneth L Nanoparticles for delivery of therapeutic agents using ultrasound and associated methods
TWI388344B (zh) * 2005-08-23 2013-03-11 Celsion Corp 儲存奈米微粒調合物之方法
US20080261913A1 (en) * 2006-12-28 2008-10-23 Idenix Pharmaceuticals, Inc. Compounds and pharmaceutical compositions for the treatment of liver disorders
WO2009040426A1 (fr) * 2007-09-28 2009-04-02 Universitätsspital Basel Immunoliposomes utilisés pour le traitement du cancer
WO2009059450A1 (fr) 2007-11-05 2009-05-14 Shanghai Jiaotong University Administration de médicament dirigée par un ligand peptidique
WO2009059449A1 (fr) * 2007-11-05 2009-05-14 Celsion Corporation Nouveaux liposomes thermosensibles contenant des agents thérapeutiques
JP2011503188A (ja) * 2007-11-14 2011-01-27 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア ステロール修飾両親媒性脂質
TWI397428B (zh) * 2009-12-29 2013-06-01 Ind Tech Res Inst 標的第四介白素受體之傳輸系統
WO2011109334A2 (fr) * 2010-03-01 2011-09-09 The Regents Of The University Of California Localisation d'agents dans un site cible comportant une composition et une source d'énergie
WO2012104277A2 (fr) * 2011-01-31 2012-08-09 Nanobiotix Procédé de surveillance de la libération par des liposomes d'un produit d'intérêt au moyen de nanoparticules superparamagnétiques

Also Published As

Publication number Publication date
AR090080A1 (es) 2014-10-15
JP6824452B2 (ja) 2021-02-03
US10251901B2 (en) 2019-04-09
CA2864469C (fr) 2020-07-07
JP2020050681A (ja) 2020-04-02
US20130230457A1 (en) 2013-09-05
CN104203216A (zh) 2014-12-10
AU2013221292A1 (en) 2014-09-11
KR20140126381A (ko) 2014-10-30
MX2014009827A (es) 2014-09-22
EP2814464A4 (fr) 2015-08-05
TW201841622A (zh) 2018-12-01
WO2013123407A1 (fr) 2013-08-22
TW201345565A (zh) 2013-11-16
RU2014133467A (ru) 2016-04-10
PH12014501866A1 (en) 2014-11-17
HK1200733A1 (en) 2015-08-14
EP2814464A1 (fr) 2014-12-24
CN106727329A (zh) 2017-05-31
CA2864469A1 (fr) 2013-08-22
ES2773299T3 (es) 2020-07-10
JP2018058858A (ja) 2018-04-12
TWI684463B (zh) 2020-02-11
KR102161271B1 (ko) 2020-09-29
EP2814464B1 (fr) 2019-12-18
US20170080003A1 (en) 2017-03-23
TWI637754B (zh) 2018-10-11
JP2015507019A (ja) 2015-03-05
CN106727329B (zh) 2020-11-03

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