[go: up one dir, main page]

SG10202008509WA - Novel polymers and dna copolymer coatings - Google Patents

Novel polymers and dna copolymer coatings

Info

Publication number
SG10202008509WA
SG10202008509WA SG10202008509WA SG10202008509WA SG10202008509WA SG 10202008509W A SG10202008509W A SG 10202008509WA SG 10202008509W A SG10202008509W A SG 10202008509WA SG 10202008509W A SG10202008509W A SG 10202008509WA SG 10202008509W A SG10202008509W A SG 10202008509WA
Authority
SG
Singapore
Prior art keywords
novel polymers
copolymer coatings
dna copolymer
dna
coatings
Prior art date
Application number
SG10202008509WA
Inventor
Andrew A Brown
Wayne N George
Alexandre Richez
Anne-Cecile Dingwall
Hatten Xavier Von
Original Assignee
Illumina Cambridge Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Illumina Cambridge Ltd filed Critical Illumina Cambridge Ltd
Publication of SG10202008509WA publication Critical patent/SG10202008509WA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/52—Amides or imides
    • C08F220/54—Amides, e.g. N,N-dimethylacrylamide or N-isopropylacrylamide
    • C08F220/56—Acrylamide; Methacrylamide
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F20/00—Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride, ester, amide, imide or nitrile thereof
    • C08F20/02—Monocarboxylic acids having less than ten carbon atoms, Derivatives thereof
    • C08F20/52—Amides or imides
    • C08F20/54—Amides, e.g. N,N-dimethylacrylamide or N-isopropylacrylamide
    • C08F20/60—Amides, e.g. N,N-dimethylacrylamide or N-isopropylacrylamide containing nitrogen in addition to the carbonamido nitrogen
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/10—Esters
    • C08F220/20—Esters of polyhydric alcohols or phenols, e.g. 2-hydroxyethyl (meth)acrylate or glycerol mono-(meth)acrylate
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/10—Esters
    • C08F220/22—Esters containing halogen
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/10—Esters
    • C08F220/26—Esters containing oxygen in addition to the carboxy oxygen
    • C08F220/28—Esters containing oxygen in addition to the carboxy oxygen containing no aromatic rings in the alcohol moiety
    • C08F220/282—Esters containing oxygen in addition to the carboxy oxygen containing no aromatic rings in the alcohol moiety and containing two or more oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/10—Esters
    • C08F220/26—Esters containing oxygen in addition to the carboxy oxygen
    • C08F220/32—Esters containing oxygen in addition to the carboxy oxygen containing epoxy radicals
    • C08F220/325—Esters containing oxygen in addition to the carboxy oxygen containing epoxy radicals containing glycidyl radical, e.g. glycidyl (meth)acrylate
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/10—Esters
    • C08F220/34—Esters containing nitrogen, e.g. N,N-dimethylaminoethyl (meth)acrylate
    • C08F220/343—Esters containing nitrogen, e.g. N,N-dimethylaminoethyl (meth)acrylate in the form of urethane links
    • C08F220/346—Esters containing nitrogen, e.g. N,N-dimethylaminoethyl (meth)acrylate in the form of urethane links and further oxygen
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/52—Amides or imides
    • C08F220/54—Amides, e.g. N,N-dimethylacrylamide or N-isopropylacrylamide
    • C08F220/60—Amides, e.g. N,N-dimethylacrylamide or N-isopropylacrylamide containing nitrogen in addition to the carbonamido nitrogen
    • C08F220/603—Amides, e.g. N,N-dimethylacrylamide or N-isopropylacrylamide containing nitrogen in addition to the carbonamido nitrogen and containing oxygen in addition to the carbonamido oxygen and nitrogen
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F222/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a carboxyl radical and containing at least one other carboxyl radical in the molecule; Salts, anhydrides, esters, amides, imides, or nitriles thereof
    • C08F222/36—Amides or imides
    • C08F222/38—Amides
    • C08F222/385—Monomers containing two or more (meth)acrylamide groups, e.g. N,N'-methylenebisacrylamide
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F285/00—Macromolecular compounds obtained by polymerising monomers on to preformed graft polymers
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F293/00—Macromolecular compounds obtained by polymerisation on to a macromolecule having groups capable of inducing the formation of new polymer chains bound exclusively at one or both ends of the starting macromolecule
    • C08F293/005—Macromolecular compounds obtained by polymerisation on to a macromolecule having groups capable of inducing the formation of new polymer chains bound exclusively at one or both ends of the starting macromolecule using free radical "living" or "controlled" polymerisation, e.g. using a complexing agent
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C08F8/30—Introducing nitrogen atoms or nitrogen-containing groups
    • C08F8/32—Introducing nitrogen atoms or nitrogen-containing groups by reaction with amines
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • C12Q1/6874—Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B50/00—Methods of creating libraries, e.g. combinatorial synthesis
    • C40B50/14—Solid phase synthesis, i.e. wherein one or more library building blocks are bound to a solid support during library creation; Particular methods of cleavage from the solid support
    • C40B50/18—Solid phase synthesis, i.e. wherein one or more library building blocks are bound to a solid support during library creation; Particular methods of cleavage from the solid support using a particular method of attachment to the solid support
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B01J2219/00632—Introduction of reactive groups to the surface
    • B01J2219/00637—Introduction of reactive groups to the surface by coating it with another layer
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718—Type of compounds synthesised
    • B01J2219/0072—Organic compounds
    • B01J2219/00722—Nucleotides
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F2438/00—Living radical polymerisation
    • C08F2438/03—Use of a di- or tri-thiocarbonylthio compound, e.g. di- or tri-thioester, di- or tri-thiocarbamate, or a xanthate as chain transfer agent, e.g . Reversible Addition Fragmentation chain Transfer [RAFT] or Macromolecular Design via Interchange of Xanthates [MADIX]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2565/00—Nucleic acid analysis characterised by mode or means of detection
    • C12Q2565/40—Detection characterised by signal amplification of label
    • C12Q2565/401—Signal amplification by chemical polymerisation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Structural Engineering (AREA)
  • Emergency Medicine (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
  • Surface Treatment Of Glass (AREA)
  • Laminated Bodies (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
SG10202008509WA 2014-10-31 2015-10-26 Novel polymers and dna copolymer coatings SG10202008509WA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201462073764P 2014-10-31 2014-10-31

Publications (1)

Publication Number Publication Date
SG10202008509WA true SG10202008509WA (en) 2020-10-29

Family

ID=54478722

Family Applications (2)

Application Number Title Priority Date Filing Date
SG10202008509WA SG10202008509WA (en) 2014-10-31 2015-10-26 Novel polymers and dna copolymer coatings
SG11201703386XA SG11201703386XA (en) 2014-10-31 2015-10-26 Novel polymers and dna copolymer coatings

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG11201703386XA SG11201703386XA (en) 2014-10-31 2015-10-26 Novel polymers and dna copolymer coatings

Country Status (16)

Country Link
US (4) US9815916B2 (en)
EP (3) EP3632944B1 (en)
JP (3) JP6759197B2 (en)
KR (1) KR102462849B1 (en)
CN (3) CN111285967B (en)
AU (2) AU2015340767B2 (en)
CA (2) CA2965578C (en)
DK (1) DK3212684T3 (en)
ES (2) ES2772127T3 (en)
IL (1) IL251872B (en)
LT (1) LT3212684T (en)
PL (1) PL3212684T3 (en)
PT (1) PT3212684T (en)
SG (2) SG10202008509WA (en)
SI (1) SI3212684T1 (en)
WO (1) WO2016066586A1 (en)

Families Citing this family (75)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG10202008509WA (en) 2014-10-31 2020-10-29 Illumina Cambridge Ltd Novel polymers and dna copolymer coatings
CN107924121B (en) 2015-07-07 2021-06-08 亿明达股份有限公司 Selective Surface Patterning via Nanoimprinting
ES2873723T3 (en) 2016-07-22 2021-11-03 Univ Oregon Health & Science Single cell whole genome collections and combinatorial indexing methods to prepare them
RU2760391C2 (en) * 2016-12-22 2021-11-24 Иллюмина, Инк. Biochips including resin film and structured polymer layer
NZ754331A (en) 2016-12-22 2025-09-26 Illumina Inc Flow cell package and method for making the same
CA3059952C (en) 2017-04-23 2023-04-18 Illumina Cambridge Limited Compositions and methods for improving sample identification in indexed nucleic acid libraries
DK3872187T3 (en) 2017-04-23 2022-12-05 Illumina Cambridge Ltd COMPOSITIONS AND METHODS FOR IMPROVING SAMPLE IDENTIFICATION IN INDEXED NUCLEIC ACID LIBRARIES
AU2018259202B2 (en) 2017-04-23 2022-03-24 Illumina Cambridge Limited Compositions and methods for improving sample identification in indexed nucleic acid libraries
RU2770879C2 (en) 2017-06-07 2022-04-22 Орегон Хэлт Энд Сайенс Юниверсити Genome-wide libraries of individual cells for bisulfite sequencing
WO2019027767A1 (en) 2017-07-31 2019-02-07 Illumina Inc. Sequencing system with multiplexed biological sample aggregation
WO2019028047A1 (en) 2017-08-01 2019-02-07 Illumina, Inc Spatial indexing of genetic material and library preparation using hydrogel beads and flow cells
CA3066535C (en) 2017-12-21 2022-08-02 Illumina, Inc. Flow cells with hydrogel coating
KR102383799B1 (en) 2018-04-02 2022-04-05 일루미나, 인코포레이티드 Compositions and methods for preparing controls for sequence-based genetic testing
AU2019270185A1 (en) 2018-05-17 2020-01-16 Illumina, Inc. High-throughput single-cell sequencing with reduced amplification bias
DK3810774T3 (en) 2018-06-04 2023-12-11 Illumina Inc HIGH-THROUGH-PUT SINGLE CELL TRANSCRIPTOME LIBRARIES AND METHODS OF PREPARATION AND USE
EP3807002A1 (en) 2018-06-14 2021-04-21 Corning Incorporated Patterned microfluidic devices and methods for manufacturing the same
TWI730352B (en) * 2018-08-06 2021-06-11 英商伊路米納劍橋有限公司 Flow cells and sequencing systems and methods of preparing substrates therefor
JP7182759B2 (en) * 2018-08-27 2022-12-05 株式会社コーセー Upper critical solution temperature type temperature-responsive polymer with nucleobase structure
US10704094B1 (en) 2018-11-14 2020-07-07 Element Biosciences, Inc. Multipart reagents having increased avidity for polymerase binding
GB2598656B (en) 2018-11-15 2023-10-04 Element Biosciences Inc Methods for generating circular nucleic acid molecules
AU2019407218B2 (en) 2018-12-18 2024-12-05 Illumina Cambridge Limited Heterocyclic azide units and their use in polymer coatings
AU2019422318B2 (en) 2019-01-14 2025-06-05 Illumina Cambridge Limited Flow cell including a heteropolymer
SG11202102530QA (en) 2019-03-01 2021-04-29 Illumina Inc High-throughput single-nuclei and single-cell libraries and methods of making and of using
NL2023316B1 (en) 2019-03-21 2020-09-28 Illumina Inc Artificial intelligence-based sequencing
NL2023311B9 (en) 2019-03-21 2021-03-12 Illumina Inc Artificial intelligence-based generation of sequencing metadata
NL2023310B1 (en) 2019-03-21 2020-09-28 Illumina Inc Training data generation for artificial intelligence-based sequencing
US11210554B2 (en) 2019-03-21 2021-12-28 Illumina, Inc. Artificial intelligence-based generation of sequencing metadata
WO2020191387A1 (en) 2019-03-21 2020-09-24 Illumina, Inc. Artificial intelligence-based base calling
US12313627B2 (en) 2019-05-01 2025-05-27 Element Biosciences, Inc. Multivalent binding composition for nucleic acid analysis
CN110305238B (en) * 2019-06-27 2021-02-26 上海应用技术大学 A kind of preparation method of side chain sugar-containing polymer containing heterogeneous sugar units
NL2023679B1 (en) * 2019-08-09 2021-04-13 Illumina Inc System and method for patterning flow cell substrates
WO2021034791A1 (en) * 2019-08-19 2021-02-25 Inscripta, Inc. Optimizing high-throughput sequencing capacity
JP7773373B2 (en) 2019-11-27 2025-11-19 イルミナ インコーポレイテッド On-flow cell three-dimensional polymer structure
PH12021552314A1 (en) * 2019-12-02 2022-06-27 Illumina Cambridge Ltd Hydrogel
NL2024749B1 (en) * 2019-12-02 2021-08-31 Illumina Cambridge Ltd Hydrogel
CN112898575B (en) * 2019-12-03 2022-10-21 深圳清华大学研究院 Preparation method of crotch-like macromolecule modified nucleotide
CN114008199A (en) 2019-12-19 2022-02-01 伊路敏纳公司 High throughput single cell libraries and methods of making and using the same
EP4139744A1 (en) * 2020-04-24 2023-03-01 Illumina Cambridge Limited Flow cells
US11188778B1 (en) 2020-05-05 2021-11-30 Illumina, Inc. Equalization-based image processing and spatial crosstalk attenuator
US12209266B2 (en) 2020-05-12 2025-01-28 Illumina, Inc. Generating nucleic acids with modified bases using recombinant terminal deoxynucleotidyl transferase
WO2021252617A1 (en) 2020-06-09 2021-12-16 Illumina, Inc. Methods for increasing yield of sequencing libraries
JP2023532231A (en) 2020-06-30 2023-07-27 イルミナ インコーポレイテッド Sequencing by Catalytically Controlled Synthesis to Generate Unblemished DNA
AU2021306281A1 (en) 2020-07-08 2023-01-05 Illumina, Inc. Beads as transposome carriers
US11361194B2 (en) 2020-10-27 2022-06-14 Illumina, Inc. Systems and methods for per-cluster intensity correction and base calling
EP4244387A1 (en) * 2020-11-16 2023-09-20 Illumina Cambridge Limited Altering flow cell signals
CN114573764B (en) * 2020-11-30 2023-08-29 深圳市真迈生物科技有限公司 Polymer, chip and its preparation method and application
CA3199918A1 (en) 2021-01-05 2022-07-14 Randall Smith Compositions including functional groups coupled to substrates, and methods of making the same
CN117043352A (en) 2021-01-29 2023-11-10 伊鲁米纳公司 Methods, compositions and kits for improving seeding efficiency of flow cells using polynucleotides
US12398422B2 (en) 2021-05-28 2025-08-26 Illumina, Inc. Fluidic devices including fluidic channels, and methods of making the same
US11455487B1 (en) 2021-10-26 2022-09-27 Illumina Software, Inc. Intensity extraction and crosstalk attenuation using interpolation and adaptation for base calling
EP4374343B1 (en) 2021-07-19 2025-12-03 Illumina, Inc. Intensity extraction with interpolation and adaptation for base calling
EP4373958A1 (en) 2021-07-23 2024-05-29 Illumina, Inc. Methods for preparing substrate surface for dna sequencing
WO2023069927A1 (en) 2021-10-20 2023-04-27 Illumina, Inc. Methods for capturing library dna for sequencing
US20250034638A1 (en) 2021-12-17 2025-01-30 3M Innovative Properties Company Articles with Photoiniferter Attached to Inorganic Oxide Surface and Polymers Prepared Therefrom
WO2023183764A1 (en) 2022-03-22 2023-09-28 Illumina Cambridge Limited Substrate with orthogonally functional nanodomains
WO2023196572A1 (en) 2022-04-07 2023-10-12 Illumina Singapore Pte. Ltd. Altered cytidine deaminases and methods of use
WO2023239917A1 (en) 2022-06-09 2023-12-14 Illumina, Inc. Dependence of base calling on flow cell tilt
WO2024038664A1 (en) 2022-08-18 2024-02-22 日本製鉄株式会社 Plated steel sheet
WO2024064639A1 (en) 2022-09-19 2024-03-28 Illumina, Inc. Nanogel particles having dual functionality and temperature responsiveness for particle clustering in nucleic acid sequencing systems
EP4594482A1 (en) 2022-09-30 2025-08-06 Illumina, Inc. Cytidine deaminases and methods of use in mapping modified cytosine nucleotides
CN120153070A (en) 2022-09-30 2025-06-13 因美纳有限公司 Helicase-cytidine deaminase complexes and methods of use thereof
EP4594343A1 (en) 2022-09-30 2025-08-06 Illumina, Inc. Methods of using cpg binding proteins in mapping modified cytosine nucleotides
EP4630153A1 (en) 2022-12-07 2025-10-15 Illumina, Inc. Etch-free photoresist patterning in multi-depth nanowells
JPWO2024204685A1 (en) 2023-03-31 2024-10-03
WO2025006431A1 (en) 2023-06-28 2025-01-02 Illumina, Inc. Photoresist patterning in multi-depth nanowells
CN116925284B (en) * 2023-07-28 2024-08-02 深圳市大道测序生物科技有限公司 Polymer and preparation method thereof, application of polymer in gene sequencing chip and sequencing chip
WO2025072783A1 (en) 2023-09-28 2025-04-03 Illumina, Inc. Altered cytidine deaminases and methods of use
WO2025081064A2 (en) 2023-10-11 2025-04-17 Illumina, Inc. Thermophilic deaminase and methods for identifying modified cytosine
EP4567128A1 (en) 2023-12-07 2025-06-11 Max-Delbrück-Centrum für Molekulare Medizin in der Helmholtz-Gemeinschaft Improved method and means for spatial nucleic acid detection in-situ
WO2025137222A1 (en) 2023-12-19 2025-06-26 Illumina, Inc. Methylation detection assay
WO2025221895A1 (en) * 2024-04-19 2025-10-23 Illumina, Inc. Water soluble polymer scaffolds for dye labeling
WO2025264831A1 (en) 2024-06-18 2025-12-26 Illumina, Inc. Methods for increasing sequencing quality of gc-rich regions
WO2025264836A1 (en) 2024-06-18 2025-12-26 Illumina, Inc. Methods for increasing sequencing quality of gc-rich regions
WO2026006314A1 (en) 2024-06-28 2026-01-02 Illumina, Inc. Tagging target regions prior to nucleotide sequencing
WO2026006774A1 (en) 2024-06-28 2026-01-02 Illumina, Inc. Altered cytidine deaminases and methods of use

Family Cites Families (101)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4734475A (en) * 1986-12-15 1988-03-29 Ciba-Geigy Corporation Wettable surface modified contact lens fabricated from an oxirane containing hydrophobic polymer
GB8810400D0 (en) 1988-05-03 1988-06-08 Southern E Analysing polynucleotide sequences
US5130238A (en) 1988-06-24 1992-07-14 Cangene Corporation Enhanced nucleic acid amplification process
GB8822228D0 (en) 1988-09-21 1988-10-26 Southern E M Support-bound oligonucleotides
US6346413B1 (en) 1989-06-07 2002-02-12 Affymetrix, Inc. Polymer arrays
US5800992A (en) 1989-06-07 1998-09-01 Fodor; Stephen P.A. Method of detecting nucleic acids
DE3924454A1 (en) 1989-07-24 1991-02-07 Cornelis P Prof Dr Hollenberg THE APPLICATION OF DNA AND DNA TECHNOLOGY FOR THE CONSTRUCTION OF NETWORKS FOR USE IN CHIP CONSTRUCTION AND CHIP PRODUCTION (DNA CHIPS)
EP0450060A1 (en) 1989-10-26 1991-10-09 Sri International Dna sequencing
US5455166A (en) 1991-01-31 1995-10-03 Becton, Dickinson And Company Strand displacement amplification
CA2118806A1 (en) 1991-09-18 1993-04-01 William J. Dower Method of synthesizing diverse collections of oligomers
JP3939338B2 (en) 1991-11-22 2007-07-04 アフィメトリックス， インコーポレイテッド Combinatorial strategies for polymer synthesis.
CA2130562A1 (en) 1992-02-19 1993-09-02 Alexander B. Chetverin Novel oligonucleotide arrays and their use for sorting, isolating, sequencing, and manipulating nucleic acids
US5583211A (en) 1992-10-29 1996-12-10 Beckman Instruments, Inc. Surface activated organic polymers useful for location - specific attachment of nucleic acids, peptides, proteins and oligosaccharides
US5472672A (en) 1993-10-22 1995-12-05 The Board Of Trustees Of The Leland Stanford Junior University Apparatus and method for polymer synthesis using arrays
US6156501A (en) 1993-10-26 2000-12-05 Affymetrix, Inc. Arrays of modified nucleic acid probes and methods of use
EP0730663B1 (en) 1993-10-26 2003-09-24 Affymetrix, Inc. Arrays of nucleic acid probes on biological chips
US5429807A (en) 1993-10-28 1995-07-04 Beckman Instruments, Inc. Method and apparatus for creating biopolymer arrays on a solid support surface
CA2185239C (en) 1994-03-16 2002-12-17 Nanibhushan Dattagupta Isothermal strand displacement nucleic acid amplification
US5552278A (en) 1994-04-04 1996-09-03 Spectragen, Inc. DNA sequencing by stepwise ligation and cleavage
US5807522A (en) 1994-06-17 1998-09-15 The Board Of Trustees Of The Leland Stanford Junior University Methods for fabricating microarrays of biological samples
US5641658A (en) 1994-08-03 1997-06-24 Mosaic Technologies, Inc. Method for performing amplification of nucleic acid with two primers bound to a single solid support
US5556752A (en) 1994-10-24 1996-09-17 Affymetrix, Inc. Surface-bound, unimolecular, double-stranded DNA
US5750341A (en) 1995-04-17 1998-05-12 Lynx Therapeutics, Inc. DNA sequencing by parallel oligonucleotide extensions
US5624711A (en) 1995-04-27 1997-04-29 Affymax Technologies, N.V. Derivatization of solid supports and methods for oligomer synthesis
US5545531A (en) 1995-06-07 1996-08-13 Affymax Technologies N.V. Methods for making a device for concurrently processing multiple biological chip assays
JPH0959315A (en) * 1995-08-18 1997-03-04 Hiroaki Egawa Aminopolyl type resin and its production
CA2227895C (en) 1995-10-11 2012-07-17 Luminex Corporation Multiplexed analysis of clinical specimens apparatus and methods
US5658734A (en) 1995-10-17 1997-08-19 International Business Machines Corporation Process for synthesizing chemical compounds
US6458530B1 (en) 1996-04-04 2002-10-01 Affymetrix Inc. Selecting tag nucleic acids
GB9620209D0 (en) 1996-09-27 1996-11-13 Cemu Bioteknik Ab Method of sequencing DNA
GB9626815D0 (en) 1996-12-23 1997-02-12 Cemu Bioteknik Ab Method of sequencing DNA
US6297006B1 (en) 1997-01-16 2001-10-02 Hyseq, Inc. Methods for sequencing repetitive sequences and for determining the order of sequence subfragments
US7622294B2 (en) 1997-03-14 2009-11-24 Trustees Of Tufts College Methods for detecting target analytes and enzymatic reactions
JP2001517948A (en) 1997-04-01 2001-10-09 グラクソ、グループ、リミテッド Nucleic acid sequencing
US6087102A (en) 1998-01-07 2000-07-11 Clontech Laboratories, Inc. Polymeric arrays and methods for their use in binding assays
US6287776B1 (en) 1998-02-02 2001-09-11 Signature Bioscience, Inc. Method for detecting and classifying nucleic acid hybridization
JP3944996B2 (en) 1998-03-05 2007-07-18 株式会社日立製作所 DNA probe array
US6031078A (en) 1998-06-16 2000-02-29 Millennium Pharmaceuticals, Inc. MTbx protein and nucleic acid molecules and uses therefor
AR021833A1 (en) 1998-09-30 2002-08-07 Applied Research Systems METHODS OF AMPLIFICATION AND SEQUENCING OF NUCLEIC ACID
US6277628B1 (en) 1998-10-02 2001-08-21 Incyte Genomics, Inc. Linear microarrays
US20050191698A1 (en) 1999-04-20 2005-09-01 Illumina, Inc. Nucleic acid sequencing using microsphere arrays
US6355431B1 (en) 1999-04-20 2002-03-12 Illumina, Inc. Detection of nucleic acid amplification reactions using bead arrays
AU4476900A (en) 1999-04-20 2000-11-02 Illumina, Inc. Detection of nucleic acid reactions on bead arrays
US20060275782A1 (en) 1999-04-20 2006-12-07 Illumina, Inc. Detection of nucleic acid reactions on bead arrays
US7244559B2 (en) 1999-09-16 2007-07-17 454 Life Sciences Corporation Method of sequencing a nucleic acid
US6274320B1 (en) 1999-09-16 2001-08-14 Curagen Corporation Method of sequencing a nucleic acid
US7582420B2 (en) 2001-07-12 2009-09-01 Illumina, Inc. Multiplex nucleic acid reactions
US6913884B2 (en) 2001-08-16 2005-07-05 Illumina, Inc. Compositions and methods for repetitive use of genomic DNA
DE60136166D1 (en) 2000-02-07 2008-11-27 Illumina Inc NUCLEIC ACID PROOF METHOD WITH UNIVERSAL PRIMING
US20020039728A1 (en) 2000-02-10 2002-04-04 Robert Kain Alternative substrates and formats for bead-based array of arrays
US6770441B2 (en) 2000-02-10 2004-08-03 Illumina, Inc. Array compositions and methods of making same
KR100352171B1 (en) * 2000-04-14 2002-09-12 (주) 제노텍 Method for attaching oligonucleotide to solid support and the oligonucleotide array prepared by the method thereof
AU8288101A (en) 2000-07-07 2002-01-21 Visigen Biotechnologies Inc Real-time sequence determination
FR2812296B1 (en) * 2000-07-25 2002-12-20 Rhodia Chimie Sa PROCESS FOR THE SYNTHESIS OF HYBRID AND ORGANIC COPOLYMERS BY CONTROLLED RADICAL POLYMERIZATION
EP1354064A2 (en) 2000-12-01 2003-10-22 Visigen Biotechnologies, Inc. Enzymatic nucleic acid synthesis: compositions and methods for altering monomer incorporation fidelity
AR031640A1 (en) 2000-12-08 2003-09-24 Applied Research Systems ISOTHERMAL AMPLIFICATION OF NUCLEIC ACIDS IN A SOLID SUPPORT
CA2443562A1 (en) 2001-04-20 2002-10-31 Emembrane, Inc. High capacity methods for separation, purification, concentration, immobilization and synthesis of compounds and applications based thereupon
GB0127564D0 (en) 2001-11-16 2002-01-09 Medical Res Council Emulsion compositions
US7057026B2 (en) 2001-12-04 2006-06-06 Solexa Limited Labelled nucleotides
US20040002090A1 (en) 2002-03-05 2004-01-01 Pascal Mayer Methods for detecting genome-wide sequence variations associated with a phenotype
US6878805B2 (en) * 2002-08-16 2005-04-12 Isis Pharmaceuticals, Inc. Peptide-conjugated oligomeric compounds
EP1530578B1 (en) 2002-08-23 2013-03-13 Illumina Cambridge Limited Modified nucleotides for polynucleotide sequencing
US7595883B1 (en) 2002-09-16 2009-09-29 The Board Of Trustees Of The Leland Stanford Junior University Biological analysis arrangement and approach therefor
JP4480715B2 (en) 2003-01-29 2010-06-16 ４５４ コーポレーション Double-end sequencing
EP1636337A4 (en) 2003-06-20 2007-07-04 Illumina Inc Methods and compositions for whole genome amplification and genotyping
EP1641809B2 (en) 2003-07-05 2018-10-03 The Johns Hopkins University Method and compositions for detection and enumeration of genetic variations
ES2949821T3 (en) 2004-01-07 2023-10-03 Illumina Cambridge Ltd Molecular arrays
KR20060103957A (en) * 2004-01-15 2006-10-04 알자 코포레이션 Liposomal Compositions for Therapeutic Delivery
US7302146B2 (en) 2004-09-17 2007-11-27 Pacific Biosciences Of California, Inc. Apparatus and method for analysis of molecules
CA2611671C (en) 2005-06-15 2013-10-08 Callida Genomics, Inc. Single molecule arrays for genetic and chemical analysis
US7405281B2 (en) 2005-09-29 2008-07-29 Pacific Biosciences Of California, Inc. Fluorescent nucleotide analogs and uses therefor
GB0522310D0 (en) 2005-11-01 2005-12-07 Solexa Ltd Methods of preparing libraries of template polynucleotides
GB0604911D0 (en) * 2006-03-10 2006-04-19 Warwick Effect Polymers Ltd Polymers
AU2007226348A1 (en) 2006-03-10 2007-09-20 Warwick Effect Polymers Ltd. Polymers
EP2021503A1 (en) 2006-03-17 2009-02-11 Solexa Ltd. Isothermal methods for creating clonal single molecule arrays
EP3373174A1 (en) 2006-03-31 2018-09-12 Illumina, Inc. Systems and devices for sequence by synthesis analysis
WO2008051530A2 (en) 2006-10-23 2008-05-02 Pacific Biosciences Of California, Inc. Polymerase enzymes and reagents for enhanced nucleic acid sequencing
US8349167B2 (en) 2006-12-14 2013-01-08 Life Technologies Corporation Methods and apparatus for detecting molecular interactions using FET arrays
JP5622392B2 (en) 2006-12-14 2014-11-12 ライフ テクノロジーズ コーポレーション Method and apparatus for analyte measurement using large-scale FET arrays
US8262900B2 (en) 2006-12-14 2012-09-11 Life Technologies Corporation Methods and apparatus for measuring analytes using large scale FET arrays
US8877936B2 (en) 2008-04-09 2014-11-04 California Institute Of Technology Ruthenium olefin metathesis catalysts bearing N-heterocyclic carbene ligands with substituted backbone
US20100137143A1 (en) 2008-10-22 2010-06-03 Ion Torrent Systems Incorporated Methods and apparatus for measuring analytes
FR2943344B1 (en) * 2009-03-18 2011-04-15 Commissariat Energie Atomique NOVEL SILAN COMPOUNDS CARRIED OUT FROM A CYCLIC CARBON CHAIN COMPRISING AN ALKYL FUNCTION TO FUNCTIONALIZE SOLID SUBSTRATE AND IMMOBILIZE BIOLOGICAL MOLECULES ON THESE SUBSTRATES
JP6080356B2 (en) * 2009-03-30 2017-02-15 テルモ株式会社 Surface treatment agent, filter medium, and blood treatment filter
EP2499213B1 (en) * 2009-11-09 2019-01-16 University Of Washington Center For Commercialization Functionalized chromophoric polymer dots and bioconjugates thereof
US9198972B2 (en) * 2010-01-28 2015-12-01 Alnylam Pharmaceuticals, Inc. Monomers and oligonucleotides comprising cycloaddition adduct(s)
EP2632593B1 (en) 2010-10-27 2021-09-29 Illumina, Inc. Flow cells for biological or chemical analysis
US8951781B2 (en) 2011-01-10 2015-02-10 Illumina, Inc. Systems, methods, and apparatuses to image a sample for biological or chemical analysis
US9962521B2 (en) * 2011-04-12 2018-05-08 University Of British Columbia Shape memory materials by surface modification
WO2012170936A2 (en) 2011-06-09 2012-12-13 Illumina, Inc. Patterned flow-cells useful for nucleic acid analysis
AU2012328662B2 (en) 2011-10-28 2015-12-17 Illumina, Inc. Microarray fabrication system and method
US9206271B2 (en) * 2012-03-25 2015-12-08 Wisconsin Alumni Research Foundation Fully backbone degradable and functionalizable polymers derived from the ring-opening metathesis polymerization (ROMP)
EP2672269A1 (en) * 2012-06-07 2013-12-11 Solarwell Enhanced affinity ligands
US9012022B2 (en) * 2012-06-08 2015-04-21 Illumina, Inc. Polymer coatings
JP2015527428A (en) * 2012-06-29 2015-09-17 ポリマーズ シーアールシー リミテッドＰｏｌｙｍｅｒｓ ＣＲＣ Ｌｔｄ． Method for modifying polymer surface
US9487729B2 (en) * 2012-10-24 2016-11-08 Exxonmobil Chemical Patents Inc. Functionalized polymers and oligomers as corrosion inhibitors and antiwear additives
US9512422B2 (en) 2013-02-26 2016-12-06 Illumina, Inc. Gel patterned surfaces
EP2970356B1 (en) * 2013-03-15 2018-05-30 Illumina Cambridge Limited Modified nucleosides or nucleotides
CN105431554B (en) * 2013-07-01 2019-02-15 Illumina公司 Catalyst-free surface functionalization and polymer grafting
AU2014312043A1 (en) * 2013-08-30 2016-02-25 Illumina France Manipulation of droplets on hydrophilic or variegated-hydrophilic surfaces
SG10202008509WA (en) * 2014-10-31 2020-10-29 Illumina Cambridge Ltd Novel polymers and dna copolymer coatings

Also Published As

Publication number Publication date
JP7095041B2 (en) 2022-07-04
KR20170099878A (en) 2017-09-01
US10208142B2 (en) 2019-02-19
AU2015340767A1 (en) 2017-05-18
ES2772127T3 (en) 2020-07-07
AU2015340767B2 (en) 2020-01-30
EP3632944B1 (en) 2021-12-01
SI3212684T1 (en) 2020-04-30
CA2965578C (en) 2024-03-19
US20190194363A1 (en) 2019-06-27
WO2016066586A1 (en) 2016-05-06
DK3212684T3 (en) 2020-03-02
ES2905706T3 (en) 2022-04-11
AU2020202856B2 (en) 2021-09-09
JP2022130521A (en) 2022-09-06
CN114805710B (en) 2023-11-17
US20200131285A1 (en) 2020-04-30
IL251872A0 (en) 2017-06-29
US20160122816A1 (en) 2016-05-05
US11447582B2 (en) 2022-09-20
CN111285967A (en) 2020-06-16
US10577439B2 (en) 2020-03-03
EP3212684B1 (en) 2019-12-11
JP2021001341A (en) 2021-01-07
PT3212684T (en) 2020-02-03
EP3212684A1 (en) 2017-09-06
EP3632944A1 (en) 2020-04-08
US20180155469A1 (en) 2018-06-07
EP3970849B1 (en) 2025-12-17
CN107108822B (en) 2020-02-07
IL251872B (en) 2021-01-31
CN107108822A (en) 2017-08-29
JP2017536444A (en) 2017-12-07
AU2020202856A1 (en) 2020-05-21
CN111285967B (en) 2022-04-05
KR102462849B1 (en) 2022-11-02
JP6759197B2 (en) 2020-09-23
PL3212684T3 (en) 2020-10-19
US9815916B2 (en) 2017-11-14
JP7588115B2 (en) 2024-11-21
LT3212684T (en) 2020-04-10
SG11201703386XA (en) 2017-05-30
CN114805710A (en) 2022-07-29
CA2965578A1 (en) 2016-05-06
EP3970849A1 (en) 2022-03-23
CA3188941A1 (en) 2016-05-06

Similar Documents

Publication Publication Date Title
IL251872A0 (en) Novel polymers and dna copolymer coatings
IL252277B (en) Novel polymers and methods for their manufacture
TWI563007B (en) Block copolymer
EP3183310A4 (en) Bio-based acrylic monomers and polymers thereof
SG11201700278UA (en) Poly(oxazoline-co-ethyleneimine)-epichlorohydrin copolymers and uses thereof
EP3157971A4 (en) Urethane acrylate polymers with unique physical properties
GB201503393D0 (en) Polymers and uses thereof
PL3328925T3 (en) Laser-markable polymers and coatings
EP3229842A4 (en) Lipocationic polymers and uses thereof
SG11201607082PA (en) New tetracyano-anthraquino-dimethane polymers and use thereof
PL3274411T3 (en) Durable anti-fingerprint polymers and coating compositions
IL258321B (en) Polymer coatings and methods for depositing polymer coatings
SMT202100585T1 (en) Polymer particles and uses thereof
EP3168250A4 (en) Fluorine-atom-containing polymer and use thereof
GB201402646D0 (en) Polymers
GB201516067D0 (en) Defined monomer sequence polymers
EP3134484A4 (en) Polycyclocarbonate compounds and polymers formed therefrom
GB201510461D0 (en) New polymers and methods
ZA201801160B (en) 3-methylene-2-pyrrolidone based polymers
GB201418068D0 (en) Polymer
GB201407092D0 (en) Polymers
SG11201703038VA (en) Antibacterial and/or antifouling polymers
GB201402404D0 (en) Polymer
IL252476A0 (en) Alternating and semi-alternating poly(ester-anhydride) copolymers
IL251518A0 (en) Astaxanthin based polymer and uses thereof