SG10201913655UA - Cells expressing chimeric activating receptors and chimeric stimulating receptors and uses thereof - Google Patents
Cells expressing chimeric activating receptors and chimeric stimulating receptors and uses thereofInfo
- Publication number
- SG10201913655UA SG10201913655UA SG10201913655UA SG10201913655UA SG10201913655UA SG 10201913655U A SG10201913655U A SG 10201913655UA SG 10201913655U A SG10201913655U A SG 10201913655UA SG 10201913655U A SG10201913655U A SG 10201913655UA SG 10201913655U A SG10201913655U A SG 10201913655UA
- Authority
- SG
- Singapore
- Prior art keywords
- receptors
- chimeric
- cells expressing
- stimulating
- activating
- Prior art date
Links
- 230000003213 activating effect Effects 0.000 title 1
- 230000004936 stimulating effect Effects 0.000 title 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0636—T lymphocytes
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
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- A61K39/0011—Cancer antigens
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- A61K40/10—Cellular immunotherapy characterised by the cell type used
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- C07K—PEPTIDES
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
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- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C07K16/2827—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C07K16/283—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against Fc-receptors, e.g. CD16, CD32, CD64
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
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- C07—ORGANIC CHEMISTRY
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- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07K2317/00—Immunoglobulins specific features
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- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
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- C07—ORGANIC CHEMISTRY
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- C07K2319/00—Fusion polypeptide
- C07K2319/33—Fusion polypeptide fusions for targeting to specific cell types, e.g. tissue specific targeting, targeting of a bacterial subspecies
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- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
- C07K2319/43—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation containing a FLAG-tag
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Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
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US201762490578P | 2017-04-26 | 2017-04-26 | |
US201762490580P | 2017-04-26 | 2017-04-26 | |
US201762490576P | 2017-04-26 | 2017-04-26 |
Publications (1)
Publication Number | Publication Date |
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SG10201913655UA true SG10201913655UA (en) | 2020-03-30 |
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ID=63918704
Family Applications (5)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201909571S SG11201909571SA (en) | 2017-04-26 | 2018-04-24 | Cells expressing chimeric activating receptors and chimeric stimulating receptors and uses thereof |
SG11201909541W SG11201909541WA (en) | 2017-04-26 | 2018-04-24 | Chimeric antibody/t-cell receptor constructs and uses thereof |
SG10201913655UA SG10201913655UA (en) | 2017-04-26 | 2018-04-24 | Cells expressing chimeric activating receptors and chimeric stimulating receptors and uses thereof |
SG10201913579WA SG10201913579WA (en) | 2017-04-26 | 2018-04-24 | Chimeric antibody/t-cell receptor constructs and uses thereof |
SG10201913656TA SG10201913656TA (en) | 2017-04-26 | 2018-04-24 | Cells expressing chimeric activating receptors and chimeric stimulating receptors and uses thereof |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
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SG11201909571S SG11201909571SA (en) | 2017-04-26 | 2018-04-24 | Cells expressing chimeric activating receptors and chimeric stimulating receptors and uses thereof |
SG11201909541W SG11201909541WA (en) | 2017-04-26 | 2018-04-24 | Chimeric antibody/t-cell receptor constructs and uses thereof |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
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SG10201913579WA SG10201913579WA (en) | 2017-04-26 | 2018-04-24 | Chimeric antibody/t-cell receptor constructs and uses thereof |
SG10201913656TA SG10201913656TA (en) | 2017-04-26 | 2018-04-24 | Cells expressing chimeric activating receptors and chimeric stimulating receptors and uses thereof |
Country Status (13)
Country | Link |
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US (5) | US11965021B2 (en) |
EP (2) | EP3615046A4 (en) |
JP (4) | JP2020517287A (en) |
KR (3) | KR102762834B1 (en) |
CN (2) | CN110662547A (en) |
AU (3) | AU2018258046B2 (en) |
CA (2) | CA3059755A1 (en) |
IL (2) | IL310182A (en) |
MX (1) | MX2024007576A (en) |
PH (1) | PH12019502411A1 (en) |
SG (5) | SG11201909571SA (en) |
TW (2) | TWI874297B (en) |
WO (3) | WO2018200585A1 (en) |
Families Citing this family (51)
Publication number | Priority date | Publication date | Assignee | Title |
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