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SE8804570D0 - New ciclosporin crystal form process for its produktion pharmaceutical compositions containing it and its use - Google Patents

New ciclosporin crystal form process for its produktion pharmaceutical compositions containing it and its use

Info

Publication number
SE8804570D0
SE8804570D0 SE8804570A SE8804570A SE8804570D0 SE 8804570 D0 SE8804570 D0 SE 8804570D0 SE 8804570 A SE8804570 A SE 8804570A SE 8804570 A SE8804570 A SE 8804570A SE 8804570 D0 SE8804570 D0 SE 8804570D0
Authority
SE
Sweden
Prior art keywords
ciclosporin
crystal form
new
pharmaceutical compositions
compositions containing
Prior art date
Application number
SE8804570A
Other languages
English (en)
Other versions
SE8804570L (sv
SE503174C2 (sv
Inventor
D Giron
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of SE8804570D0 publication Critical patent/SE8804570D0/sv
Publication of SE8804570L publication Critical patent/SE8804570L/sv
Publication of SE503174C2 publication Critical patent/SE503174C2/sv

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64Cyclic peptides containing only normal peptide links
    • C07K7/645Cyclosporins; Related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682Processes
    • A61K9/1688Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
SE8804570A 1987-12-21 1988-12-19 Ciclosporinkristallformer, förfarande för dess framställning, farmaceutiska kompositioner innehållande densamma samt dess användning SE503174C2 (sv)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13623087A 1987-12-21 1987-12-21
US17261388A 1988-03-24 1988-03-24
US21254888A 1988-06-28 1988-06-28

Publications (3)

Publication Number Publication Date
SE8804570D0 true SE8804570D0 (sv) 1988-12-19
SE8804570L SE8804570L (sv) 1989-06-22
SE503174C2 SE503174C2 (sv) 1996-04-15

Family

ID=27384838

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8804570A SE503174C2 (sv) 1987-12-21 1988-12-19 Ciclosporinkristallformer, förfarande för dess framställning, farmaceutiska kompositioner innehållande densamma samt dess användning

Country Status (27)

Country Link
JP (1) JPH0791316B2 (sv)
KR (1) KR100188305B1 (sv)
AT (1) AT403163B (sv)
AU (1) AU626274B2 (sv)
BE (1) BE1002665A4 (sv)
CA (1) CA1341396C (sv)
CH (1) CH677926A5 (sv)
CY (1) CY1799A (sv)
DE (1) DE3843054C2 (sv)
DK (1) DK175220B1 (sv)
ES (1) ES2012580A6 (sv)
FI (1) FI89065C (sv)
FR (1) FR2624863B1 (sv)
GB (1) GB2211848B (sv)
GR (1) GR1002486B (sv)
HK (1) HK102894A (sv)
HU (1) HU203564B (sv)
IE (1) IE62006B1 (sv)
IL (1) IL88719A0 (sv)
IT (1) IT1235356B (sv)
LU (1) LU87409A1 (sv)
MY (1) MY103943A (sv)
NL (1) NL195096C (sv)
NO (1) NO177228C (sv)
NZ (1) NZ227384A (sv)
SE (1) SE503174C2 (sv)
SG (1) SG99494G (sv)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5639724A (en) 1984-07-24 1997-06-17 Sandoz Ltd. Cyclosporin galenic forms
US6007840A (en) * 1988-09-16 1999-12-28 Novartis Ag Pharmaceutical compositions comprising cyclosporins
KR0148748B1 (ko) * 1988-09-16 1998-08-17 장 크라메르, 한스 루돌프 하우스 사이클로스포린을 함유하는 약학조성물
US7081445B2 (en) 1989-02-20 2006-07-25 Novartis Ag Cyclosporin galenic forms
US5294604A (en) * 1989-12-20 1994-03-15 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Method of treating ocular diseases by periocular administration of cyclosporine A or G
GB9105705D0 (en) * 1991-03-18 1991-05-01 Sandoz Ltd Improvements in or relating to organic compounds
US6262022B1 (en) 1992-06-25 2001-07-17 Novartis Ag Pharmaceutical compositions containing cyclosporin as the active agent
JP3631490B2 (ja) * 1992-05-13 2005-03-23 ノバルティス ファーマ株式会社 シクロスポリン含有眼科用組成物
PT589843E (pt) 1992-09-25 2002-04-29 Novartis Ag Composicoes farmaceuticas contendo ciclosporinas
DK0789580T3 (da) 1994-11-03 2002-09-09 Novartis Ag Nye præparatformer for cyclosporin til oral administration med simpel sammensætning og høj biotilgængelighed, og fremgangsmåder til deres fremstilling
US5962019A (en) * 1995-08-25 1999-10-05 Sangstat Medical Corporation Oral cyclosporin formulations
US5766629A (en) 1995-08-25 1998-06-16 Sangstat Medical Corporation Oral cyclosporin formulations
DE19544507B4 (de) 1995-11-29 2007-11-15 Novartis Ag Cyclosporin enthaltende Präparate
US6262054B1 (en) * 1996-02-01 2001-07-17 Sloan-Kettering Institute Of Cancer Research Combination therapy method for treating breast cancer using edatrexate
SK285019B6 (sk) 1997-01-30 2006-04-06 Novartis Ag Tvrdá želatínová tobolka
TW581681B (en) 1998-02-20 2004-04-01 Nektar Therapeutics Liquid crystal forms of cyclosporin
US7732404B2 (en) 1999-12-30 2010-06-08 Dexcel Ltd Pro-nanodispersion for the delivery of cyclosporin
JP2007518804A (ja) 2004-01-20 2007-07-12 アラーガン、インコーポレイテッド トリアムシノロンアセトニドおよびヒアルロン酸を好ましく含有する眼局所治療用組成物
CN1763084B (zh) * 2005-10-11 2010-04-21 山东新时代药业有限公司 高纯度环孢菌素a的制备方法
BR112013030554B1 (pt) * 2011-05-27 2020-12-15 Allergan, Inc. Forma cristalina de ciclosporina a, métodos de preparação e métodos para uso da mesma
ES2666191T3 (es) * 2011-11-15 2018-05-03 Allergan, Inc. Un proceso para la cristalización de la forma 2 de la ciclosporina A
BR112014011744A2 (pt) 2011-11-15 2017-05-02 Allergan Inc formulação de ação sustentável da forma 2 de ciclosporina
EP2779994B1 (en) * 2011-11-15 2020-02-19 Allergan, Inc. Suspensions of cyclosporin a form 2
BR112014011733A2 (pt) * 2011-11-15 2017-05-09 Allergan Inc suspensões autoclaváveis da forma 2 de ciclosporina a
JPWO2024085235A1 (sv) * 2022-10-20 2024-04-25

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH614931A5 (sv) * 1975-11-04 1979-12-28 Sandoz Ag
CH640519A5 (en) * 1976-04-09 1984-01-13 Sandoz Ag Process for preparing a modified form of the antibiotic S 7481/F-1
US4117118A (en) * 1976-04-09 1978-09-26 Sandoz Ltd. Organic compounds
DE2819094A1 (de) * 1977-05-10 1978-11-23 Sandoz Ag Cyclosporin-derivate, ihre verwendung und herstellung
CH637124A5 (en) * 1978-10-18 1983-07-15 Sandoz Ag Antibiotic, its preparation and use

Also Published As

Publication number Publication date
SE8804570L (sv) 1989-06-22
GB2211848A (en) 1989-07-12
NO177228C (no) 1995-08-09
ATA309588A (de) 1997-04-15
IT8848690A0 (it) 1988-12-20
FI89065C (sv) 1993-09-30
KR100188305B1 (ko) 1999-06-01
FR2624863A1 (fr) 1989-06-23
JPH01211598A (ja) 1989-08-24
ES2012580A6 (es) 1990-04-01
NO885625L (no) 1989-06-22
KR890009975A (ko) 1989-08-05
NL195096C (nl) 2004-02-09
GR1002486B (el) 1996-12-09
DK705488D0 (da) 1988-12-19
NO885625D0 (no) 1988-12-19
GR880100850A (el) 1994-03-31
NO177228B (no) 1995-05-02
CY1799A (en) 1995-02-17
NZ227384A (en) 1991-09-25
AU2705588A (en) 1989-06-22
AU626274B2 (en) 1992-07-30
LU87409A1 (fr) 1989-07-07
MY103943A (en) 1993-10-30
FR2624863B1 (fr) 1991-04-26
FI885869A0 (fi) 1988-12-19
NL8803125A (nl) 1989-07-17
HK102894A (en) 1994-09-30
IE62006B1 (en) 1994-12-14
DE3843054C2 (de) 2003-08-21
JPH0791316B2 (ja) 1995-10-04
HU203564B (en) 1991-08-28
SE503174C2 (sv) 1996-04-15
BE1002665A4 (fr) 1991-04-30
FI885869L (fi) 1989-06-22
FI89065B (fi) 1993-04-30
IL88719A0 (en) 1989-07-31
IT1235356B (it) 1992-06-30
AT403163B (de) 1997-11-25
DE3843054A1 (de) 1989-07-27
DK175220B1 (da) 2004-07-12
GB8829556D0 (en) 1989-02-08
CH677926A5 (sv) 1991-07-15
DK705488A (da) 1989-06-22
HUT49893A (en) 1989-11-28
CA1341396C (en) 2002-11-05
SG99494G (en) 1994-10-28
IE883779L (en) 1989-06-21
GB2211848B (en) 1991-11-06

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