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SE7411650L - - Google Patents

Info

Publication number
SE7411650L
SE7411650L SE7411650A SE7411650A SE7411650L SE 7411650 L SE7411650 L SE 7411650L SE 7411650 A SE7411650 A SE 7411650A SE 7411650 A SE7411650 A SE 7411650A SE 7411650 L SE7411650 L SE 7411650L
Authority
SE
Sweden
Prior art keywords
hydrogen
alkyl
carbon
pyrazole
halogen
Prior art date
Application number
SE7411650A
Other versions
SE416648B (en
Inventor
M Garber
W J Stepek
L J Ross
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of SE7411650L publication Critical patent/SE7411650L/xx
Publication of SE416648B publication Critical patent/SE416648B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Catalysts (AREA)

Abstract

1477020 3,5-Diphenylpyrazole AMERICAN CYANAMID CO 15 Aug 1974 [17 Sept 1973] 36038/74 Heading C2C Compounds (I), where R 1 and R 2 are the groups A and B respectively, where Y, Z, Y<SP>1</SP>, Z<SP>1</SP> are hydrogen, halogen, methylthio, methylsulphonyl, cyano, carboxy, C 1-4 carboalkoxy. C 1-4 alkyl, C 1-4 haloalkyl (containing 1-4 halogen atoms) or C 1-4 alkoxy, are made by refluxing a pyrazole (II) in the presence of a catalyst selected from (a) Pd on carbon, (b) Pt on carbon and (c) pre-reduced copper chromite and an inert solvent the latter having a boiling point of at least 200‹ C. when catalyst (c) above is used, and the preparation of a compound (III) where R 3 is C 1-4 alkyl, attached to one or other of the ring nitrogen atoms by alkylating the corresponding pyrazole where R 3 is hydrogen. Pyrazolines (II), where R is hydrogen are made by a ketone R 1 COCH 3 with an aldehyde R 2 CHO, in the presence of a base, in a C 1-4 alcohol at 10-70‹ C., acidifying the mixture to below pH7 and treating the product with hydrazine at below 70‹ C.
SE7411650A 1973-09-17 1974-09-16 PROCEDURE FOR PREPARATION OF PYRAZOLES SE416648B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US39828473A 1973-09-17 1973-09-17

Publications (2)

Publication Number Publication Date
SE7411650L true SE7411650L (en) 1975-03-18
SE416648B SE416648B (en) 1981-01-26

Family

ID=23574783

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7411650A SE416648B (en) 1973-09-17 1974-09-16 PROCEDURE FOR PREPARATION OF PYRAZOLES

Country Status (20)

Country Link
JP (1) JPS5855143B2 (en)
AR (1) AR225264A1 (en)
AT (1) AT339893B (en)
BE (1) BE819948A (en)
BR (1) BR7407147D0 (en)
CA (1) CA1037048A (en)
CH (1) CH596185A5 (en)
CS (1) CS178177B2 (en)
DD (1) DD115667A5 (en)
DE (1) DE2441504A1 (en)
DK (1) DK134643B (en)
ES (1) ES430129A1 (en)
FR (1) FR2243943B1 (en)
GB (1) GB1477020A (en)
IL (1) IL45399A (en)
IT (1) IT1029578B (en)
NL (1) NL168832C (en)
SE (1) SE416648B (en)
SU (1) SU645567A3 (en)
ZA (1) ZA744908B (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3910949A (en) * 1974-12-09 1975-10-07 American Cyanamid Co Manufacture of 1,2-dimethyl-3,5-diphenylpyrazolium methylsulfate in a single reaction zone
DE3029160A1 (en) * 1980-08-01 1982-03-04 Basf Ag, 6700 Ludwigshafen METHOD FOR PRODUCING PYRAZOLES
US4749812A (en) * 1985-05-27 1988-06-07 Mitsui Toatsu Chemicals, Inc. N-(3-chloro-4-isopropylphenyl) carboxamide derivative and selective herbicide
AU5467699A (en) 1998-08-07 2000-02-28 Chiron Corporation Substituted isoxazole as estrogen receptor modulators
WO2000007996A2 (en) * 1998-08-07 2000-02-17 Chiron Corporation Pyrazoles as estrogen receptor modulators
USRE39708E1 (en) 1998-08-07 2007-06-26 Chiron Corporation Estrogen receptor modulators
AU2005287170B2 (en) * 2004-09-17 2012-03-29 Exelixis, Inc Pyrazole kinase modulators and methods of use
PL2307381T3 (en) * 2008-06-09 2021-07-05 Ludwig-Maximilians-Universität München New drugs for inhibiting aggregation of proteins involved in diseases linked to protein aggregation and/or neurodegenerative diseases

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2260485C2 (en) * 1971-12-17 1983-12-29 American Cyanamid Co., Wayne, N.J. 1,2-dialkyl-3,5-diphenylpyrazolium salts and herbicidal agents containing them
DE3209148A1 (en) * 1982-03-13 1983-09-22 Basf Ag, 6700 Ludwigshafen METHOD FOR PRODUCING PYRAZOLES BY CATALYTIC DEHYDRATION OF PYRAZOLINES

Also Published As

Publication number Publication date
DK134643C (en) 1977-05-16
CH596185A5 (en) 1978-03-15
JPS5058068A (en) 1975-05-20
FR2243943B1 (en) 1986-07-04
DK134643B (en) 1976-12-13
DK487274A (en) 1975-05-12
ZA744908B (en) 1975-08-27
GB1477020A (en) 1977-06-22
BE819948A (en) 1975-03-17
NL168832B (en) 1981-12-16
CA1037048A (en) 1978-08-22
FR2243943A1 (en) 1975-04-11
BR7407147D0 (en) 1975-07-29
AU7202874A (en) 1976-03-11
IL45399A0 (en) 1974-11-29
DE2441504A1 (en) 1975-03-20
SE416648B (en) 1981-01-26
DD115667A5 (en) 1975-10-12
AR225264A1 (en) 1982-03-15
JPS5855143B2 (en) 1983-12-08
NL7412119A (en) 1975-03-19
IL45399A (en) 1979-01-31
NL168832C (en) 1982-05-17
CS178177B2 (en) 1977-08-31
AT339893B (en) 1977-11-10
IT1029578B (en) 1979-03-20
ES430129A1 (en) 1977-01-16
ATA738174A (en) 1977-03-15
SU645567A3 (en) 1979-01-30
DE2441504C2 (en) 1987-11-26

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