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SE465928B - 1,2,4-triazolonfoereningar med antidepressiv aktivitet, foerfarande foer framstaellning av dessa och en farmaceutisk komposition - Google Patents

1,2,4-triazolonfoereningar med antidepressiv aktivitet, foerfarande foer framstaellning av dessa och en farmaceutisk komposition

Info

Publication number
SE465928B
SE465928B SE8404869A SE8404869A SE465928B SE 465928 B SE465928 B SE 465928B SE 8404869 A SE8404869 A SE 8404869A SE 8404869 A SE8404869 A SE 8404869A SE 465928 B SE465928 B SE 465928B
Authority
SE
Sweden
Prior art keywords
compound
formula
hydrogen
pharmaceutically acceptable
alkyl
Prior art date
Application number
SE8404869A
Other languages
English (en)
Swedish (sv)
Other versions
SE8404869L (sv
SE8404869D0 (sv
Inventor
R E Gammans
D W Smith
J P Yevich
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24145128&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SE465928(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of SE8404869D0 publication Critical patent/SE8404869D0/xx
Publication of SE8404869L publication Critical patent/SE8404869L/xx
Publication of SE465928B publication Critical patent/SE465928B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C243/00—Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D249/12—Oxygen or sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
SE8404869A 1983-09-30 1984-09-28 1,2,4-triazolonfoereningar med antidepressiv aktivitet, foerfarande foer framstaellning av dessa och en farmaceutisk komposition SE465928B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/538,027 US4613600A (en) 1983-09-30 1983-09-30 Antidepressant 1,2,4-triazolone compounds

Publications (3)

Publication Number Publication Date
SE8404869D0 SE8404869D0 (sv) 1984-09-28
SE8404869L SE8404869L (sv) 1985-03-31
SE465928B true SE465928B (sv) 1991-11-18

Family

ID=24145128

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8404869A SE465928B (sv) 1983-09-30 1984-09-28 1,2,4-triazolonfoereningar med antidepressiv aktivitet, foerfarande foer framstaellning av dessa och en farmaceutisk komposition

Country Status (25)

Country Link
US (1) US4613600A (xx)
JP (1) JPS60100560A (xx)
KR (1) KR880002624B1 (xx)
AT (1) AT387963B (xx)
AU (1) AU561460B2 (xx)
BE (1) BE900714A (xx)
CA (1) CA1237723A (xx)
CH (1) CH661924A5 (xx)
CY (1) CY1541A (xx)
DE (1) DE3435745C2 (xx)
DK (1) DK169546B1 (xx)
ES (1) ES8601966A1 (xx)
FI (1) FI83310C (xx)
FR (1) FR2552759B1 (xx)
GB (1) GB2147297B (xx)
GR (1) GR80475B (xx)
HK (1) HK37391A (xx)
IE (1) IE58084B1 (xx)
IT (1) IT1178522B (xx)
LU (1) LU85561A1 (xx)
MY (1) MY102123A (xx)
NL (1) NL8402946A (xx)
SE (1) SE465928B (xx)
YU (1) YU45667B (xx)
ZA (1) ZA847589B (xx)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4487773A (en) * 1981-03-16 1984-12-11 Mead Johnson & Company 1,2,4-Triazol-3-one antidepressants
YU44721B (en) * 1983-11-30 1990-12-31 Bristol Myers Co Process for obtaining 4-(2-phenoxyethyl)-1,2,4-triazolone
CA1331757C (en) * 1988-02-29 1994-08-30 Janssen Pharmaceutica Naamloze Vennootschap 5-lipoxygenase inhibiting 4-(4-phenyl-1-piperazinyl)phenols
US5504086A (en) * 1989-10-17 1996-04-02 Ellinwood, Jr.; Everett H. Intraoral dosing method of administering trifluorobenzodiazepines, propoxyphene, and nefazodone
US5256664A (en) * 1992-04-28 1993-10-26 Bristol-Myers Squibb Company Antidepressant 3-halophenylpiperazinylpropyl derivatives of substituted triazolones and triazoldiones
DE4425144A1 (de) * 1994-07-15 1996-01-18 Basf Ag Triazolverbindungen und deren Verwendung
US6403593B1 (en) 1995-07-14 2002-06-11 Abbott Laboratories Triazole compounds and the use thereof
DE19728996A1 (de) 1997-07-07 1999-01-14 Basf Ag Triazolverbindungen und deren Verwendung
CA2369732A1 (en) * 1999-04-09 2000-10-19 Sepracor Inc. R-hydroxynefazodone
US6469008B2 (en) 1999-04-09 2002-10-22 Sepracor Inc. (R)-hydroxynefazodone antipsychotic therapy
JP2002541192A (ja) 1999-04-09 2002-12-03 セプラコール， インク． Ｓ−ヒドロキシネファゾドン
US6586437B2 (en) 1999-04-09 2003-07-01 Sepracor Inc. (S)-hydroxynefazodone antipsychotic therapy
US20030129186A1 (en) 2001-07-25 2003-07-10 Biomarin Pharmaceutical Inc. Compositions and methods for modulating blood-brain barrier transport
WO2005102366A2 (en) * 2004-04-19 2005-11-03 Philip Maxwell Satow Lithium combinations, and uses related thereto
DK1889198T3 (da) 2005-04-28 2015-02-09 Proteus Digital Health Inc Farma-informatiksystem
MX2009002893A (es) 2006-09-18 2009-07-10 Raptor Pharmaceutical Inc Tratamiento de trastornos hepaticos mediante la administracion de conjugados de la proteina asociada al receptor (rap).
US9339500B2 (en) * 2008-03-04 2016-05-17 Intra-Cellular Therapies, Inc. Methods of treating vasomotor symptoms
AU2010216512B2 (en) 2009-02-20 2016-06-30 2-Bbb Medicines B.V. Glutathione-based drug delivery system
MY163048A (en) 2009-05-06 2017-08-15 Laboratory Skin Care Inc Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates
WO2012072665A1 (en) 2010-11-30 2012-06-07 Pharmaneuroboost N.V. Compositions comprising pipamperone and serotonin antagonist reuptake inhibitors
EP2753179A4 (en) * 2011-09-09 2015-03-04 Univ Leland Stanford Junior TOPICAL ITRACONAZOLE FORMULATIONS AND THEIR USE

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1066857B (it) * 1965-12-15 1985-03-12 Acraf Derivati della s ipiazolo 4.3 a piridina e processi per la loro preparazione
IT1052119B (it) * 1972-10-16 1981-06-20 Sigma Tau Ind Farmaceuti Derivati del triazolinone e procedimento per la loro preparazione
US4338317A (en) * 1981-03-16 1982-07-06 Mead Johnson & Company Phenoxyethyl-1,2,4,-triazol-3-one antidepressants

Also Published As

Publication number Publication date
YU172184A (en) 1986-10-31
AU561460B2 (en) 1987-05-07
CY1541A (en) 1991-03-22
FI843779L (fi) 1985-03-31
CA1237723A (en) 1988-06-07
IE842476L (en) 1985-03-30
MY102123A (en) 1992-03-31
FR2552759B1 (fr) 1988-10-07
LU85561A1 (fr) 1985-06-04
SE8404869L (sv) 1985-03-31
CH661924A5 (de) 1987-08-31
NL8402946A (nl) 1985-04-16
ES536286A0 (es) 1985-11-16
GB8424535D0 (en) 1984-11-07
FR2552759A1 (fr) 1985-04-05
GB2147297A (en) 1985-05-09
DE3435745A1 (de) 1985-04-11
YU45667B (sh) 1992-07-20
ES8601966A1 (es) 1985-11-16
KR850002270A (ko) 1985-05-10
US4613600A (en) 1986-09-23
DK468284A (da) 1985-03-31
IT8422922A0 (it) 1984-09-28
KR880002624B1 (ko) 1988-12-07
BE900714A (fr) 1985-03-28
ZA847589B (en) 1985-05-29
HK37391A (en) 1991-05-24
ATA310884A (de) 1988-09-15
DK169546B1 (da) 1994-11-28
JPS60100560A (ja) 1985-06-04
IT1178522B (it) 1987-09-09
DK468284D0 (da) 1984-09-28
FI83310C (fi) 1991-06-25
AT387963B (de) 1989-04-10
IE58084B1 (en) 1993-06-30
FI83310B (fi) 1991-03-15
SE8404869D0 (sv) 1984-09-28
GB2147297B (en) 1987-04-15
JPH0542435B2 (xx) 1993-06-28
FI843779A0 (fi) 1984-09-26
DE3435745C2 (de) 1994-11-03
AU3364884A (en) 1985-04-04
GR80475B (en) 1985-01-31

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