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SE447250B - Nya enkafalinderivat - Google Patents

Nya enkafalinderivat

Info

Publication number
SE447250B
SE447250B SE8004254A SE8004254A SE447250B SE 447250 B SE447250 B SE 447250B SE 8004254 A SE8004254 A SE 8004254A SE 8004254 A SE8004254 A SE 8004254A SE 447250 B SE447250 B SE 447250B
Authority
SE
Sweden
Prior art keywords
hydrogen
formula
compound according
acid
pharmaceutically acceptable
Prior art date
Application number
SE8004254A
Other languages
English (en)
Swedish (sv)
Other versions
SE8004254L (sv
Inventor
A A Carr
R A Farr
J M Kane
Original Assignee
Richardson Merrell Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richardson Merrell Inc filed Critical Richardson Merrell Inc
Publication of SE8004254L publication Critical patent/SE8004254L/xx
Publication of SE447250B publication Critical patent/SE447250B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/06—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members
    • C07D241/08—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1024—Tetrapeptides with the first amino acid being heterocyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
SE8004254A 1979-06-21 1980-06-06 Nya enkafalinderivat SE447250B (sv)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US5095079A 1979-06-21 1979-06-21
US06/130,431 US4341698A (en) 1979-06-21 1980-03-14 Enkaphalin derivatives
AU91877/82A AU559278B2 (en) 1979-06-21 1982-12-24 Piperazines

Publications (2)

Publication Number Publication Date
SE8004254L SE8004254L (sv) 1980-12-22
SE447250B true SE447250B (sv) 1986-11-03

Family

ID=36764304

Family Applications (3)

Application Number Title Priority Date Filing Date
SE8004254A SE447250B (sv) 1979-06-21 1980-06-06 Nya enkafalinderivat
SE8500878A SE460541B (sv) 1979-06-21 1985-02-22 Nya 6-oxo-2-piperazinkarboxylsyraestrar samt foerfarande foer framstaellning daerav
SE8500877A SE460540B (sv) 1979-06-21 1985-02-22 Nya 2-oxopiperazinfoereningar samt foerfarande foer framstaellning daerav

Family Applications After (2)

Application Number Title Priority Date Filing Date
SE8500878A SE460541B (sv) 1979-06-21 1985-02-22 Nya 6-oxo-2-piperazinkarboxylsyraestrar samt foerfarande foer framstaellning daerav
SE8500877A SE460540B (sv) 1979-06-21 1985-02-22 Nya 2-oxopiperazinfoereningar samt foerfarande foer framstaellning daerav

Country Status (17)

Country Link
US (1) US4341698A (no)
AU (1) AU559278B2 (no)
CA (1) CA1161838A (no)
CH (2) CH645363A5 (no)
DE (1) DE3022401A1 (no)
DK (1) DK265780A (no)
ES (1) ES8105720A1 (no)
FR (2) FR2459236A1 (no)
GB (3) GB2051821B (no)
IE (1) IE49834B1 (no)
IL (1) IL60245A (no)
IT (1) IT1148277B (no)
NL (1) NL8003580A (no)
NO (1) NO801855L (no)
NZ (1) NZ193934A (no)
PH (1) PH19222A (no)
SE (3) SE447250B (no)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6262047B1 (en) 1996-10-11 2001-07-17 Cor Therapeutics, Inc. Selective factor Xa inhibitors
US6063794A (en) 1996-10-11 2000-05-16 Cor Therapeutics Inc. Selective factor Xa inhibitors
US6369080B2 (en) 1996-10-11 2002-04-09 Cor Therapeutics, Inc. Selective factor Xa inhibitors
US6194435B1 (en) 1996-10-11 2001-02-27 Cor Therapeutics, Inc. Lactams as selective factor Xa inhibitors
EP0977772A1 (en) 1997-04-14 2000-02-09 Cor Therapeutics, Inc. SELECTIVE FACTOR Xa INHIBITORS
US6369063B1 (en) 1997-04-14 2002-04-09 Cor Therapeutics, Inc. Selective factor Xa inhibitors
CA2285705A1 (en) * 1997-04-14 1998-10-22 Cor Therapeutics, Inc. Selective factor xa inhibitors
US6228854B1 (en) 1997-08-11 2001-05-08 Cor Therapeutics, Inc. Selective factor Xa inhibitors
US6218382B1 (en) 1997-08-11 2001-04-17 Cor Therapeutics, Inc Selective factor Xa inhibitors
US6333321B1 (en) 1997-08-11 2001-12-25 Cor Therapeutics, Inc. Selective factor Xa inhibitors
CA2601709C (en) 2005-03-22 2017-02-14 Azevan Pharmaceuticals, Inc. Beta-lactamylalkanoic acids
RU2466991C2 (ru) 2005-07-19 2012-11-20 Эйзеван Фармасьютиклз, Инк. β-ЛАКТАМИЛЗАМЕЩЕННЫЕ АНАЛОГИ ФЕНИЛАЛАНИНА, ЦИСТЕИНА И СЕРИНА В КАЧЕСТВЕ АНТАГОНИСТОВ ВАЗОПРЕССИНА
JP2009532385A (ja) * 2006-03-30 2009-09-10 パラティン・テクノロジーズ・インコーポレーテッド 線状ナトリウム利尿ペプチド構築物
US8114844B2 (en) * 2006-03-30 2012-02-14 Palatin Technologies, Inc. Linear and cyclic melanocortin receptor-specific peptidomimetics
US8580746B2 (en) 2006-03-30 2013-11-12 Palatin Technologies, Inc. Amide linkage cyclic natriuretic peptide constructs
ATE539762T1 (de) * 2006-03-30 2012-01-15 Palatin Technologies Inc Aminosäureersatz für peptidkonstruktionen
US7964181B2 (en) * 2006-03-30 2011-06-21 Palatin Technologies, Inc. Amino acid surrogates for peptidic constructs
WO2007115175A2 (en) * 2006-03-30 2007-10-11 Palatin Technologies, Inc. Cyclic natriuretic peptide constructs
PL2354124T3 (pl) * 2006-12-19 2013-07-31 Hoffmann La Roche Pochodne heteroarylopirolidynylo- i piperydynyloketonów
JP2011524396A (ja) * 2008-06-18 2011-09-01 エフ．ホフマン−ラ ロシュ アーゲー Ｍｒｉとしてのアリールケトン
ES2858499T3 (es) 2010-07-01 2021-09-30 Azevan Pharmaceuticals Inc Compuestos para su uso en el tratamiento de trastorno explosivo intermitente
EP3122743B1 (en) 2014-03-28 2022-11-09 Azevan Pharmaceuticals, Inc. Compositions and methods for treating neurodegenerative diseases
AU2018333051B2 (en) 2017-09-15 2024-03-21 Azevan Pharmaceuticals, Inc. Compositions and methods for treating brain injury

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2604845A1 (de) * 1976-02-07 1977-08-18 Knoll Ag Neue piperazinderivate
US4254107A (en) * 1979-11-27 1981-03-03 Merck & Co., Inc. Long-lasting agonists of enkephalin

Also Published As

Publication number Publication date
SE460541B (sv) 1989-10-23
GB2132605B (en) 1985-01-03
SE8500877L (sv) 1985-02-22
IT8049032A0 (it) 1980-06-20
ES492566A0 (es) 1981-06-16
GB2051821A (en) 1981-01-21
ES8105720A1 (es) 1981-06-16
CH648835A5 (de) 1985-04-15
IE49834B1 (en) 1985-12-25
DK265780A (da) 1980-12-22
US4341698A (en) 1982-07-27
FR2459236A1 (fr) 1981-01-09
NL8003580A (nl) 1980-12-23
GB2106515A (en) 1983-04-13
IE801152L (en) 1980-12-21
AU9187782A (en) 1983-04-21
SE460540B (sv) 1989-10-23
DE3022401A1 (de) 1981-01-08
NZ193934A (en) 1983-02-15
CA1161838A (en) 1984-02-07
IL60245A (en) 1985-08-30
FR2473042B1 (no) 1983-07-01
CH645363A5 (de) 1984-09-28
FR2459236B1 (no) 1984-01-06
SE8004254L (sv) 1980-12-22
PH19222A (en) 1986-02-12
GB2132605A (en) 1984-07-11
SE8500877D0 (sv) 1985-02-22
GB2051821B (en) 1983-04-27
FR2473042A1 (fr) 1981-07-10
AU559278B2 (en) 1987-03-05
NO801855L (no) 1980-12-22
SE8500878D0 (sv) 1985-02-22
IT1148277B (it) 1986-11-26
GB2106515B (en) 1983-11-23

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